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Volumn 28, Issue 34, 2010, Pages 5533-5542

J-LEAPS vaccines initiate murine Th1 responses by activating dendritic cells

Author keywords

Adoptive transfer; Dendritic cells; HIV; HSV; IL12; LEAPS; Th1; Vaccines

Indexed keywords

ASPARTYLLEUCYLLEUCYLLYSYLASPARAGINYLGLYCYLGLUTAMYLARGINYLISOLEUCYLGLUTAMYLLYSYLVALYLGLUTAMIC ACID; CD11 ANTIGEN; CD8 ANTIGEN; CD86 ANTIGEN; EPITOPE; GAG PROTEIN; GAMMA INTERFERON; GLYCOPROTEIN D; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 6; SERYLLEUCYLLYSYLMETHIONYLALANYLASPARTYLPROLYLASPARAGINYLARGINYLPHENYLALANYLARGINYLGLYCYLLYSYLASPARTYLLEUCYLPROLINE; TUMOR NECROSIS FACTOR ALPHA; TYROSYLSERYLVALYLHISTIDYLGLUTAMINYLARGINYLISOLEUCYLASPARTYLVALYLLYSYLASPARTYLTHREONYLLYSYLGLUTAMYLALANYLLEUCYLGLUTAMYLLYSYLISOLEUCYLGLUTAMYLGLUTAMYLGLUTAMYLGLUTAMINYLASPARAGINYLLYSYLSERYLLYSYLLYSYLLYSYLALANINE; UNCLASSIFIED DRUG; VIRUS VACCINE; GLYCOPROTEIN D, HUMAN HERPESVIRUS 1; INTERLEUKIN 12; VIRUS ENVELOPE PROTEIN;

EID: 77955052320     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.06.043     Document Type: Article
Times cited : (17)

References (37)
  • 1
    • 0021111991 scopus 로고
    • Arginine 45 is a major part of the igenic determinant of human beta-2-microglobulin recognized by mouse monoclonal antibody BBM.1
    • Parham P., Androlewicz M., Holmes N., Rothenberg B. Arginine 45 is a major part of the igenic determinant of human beta-2-microglobulin recognized by mouse monoclonal antibody BBM.1. J Biol Chem 1983, 258:6179-6186.
    • (1983) J Biol Chem , vol.258 , pp. 6179-6186
    • Parham, P.1    Androlewicz, M.2    Holmes, N.3    Rothenberg, B.4
  • 2
    • 17444374626 scopus 로고    scopus 로고
    • Immune peptide enhancement of peptide based vaccines
    • Rosenthal K.S. Immune peptide enhancement of peptide based vaccines. Front Biosci 2005, 10:478-482.
    • (2005) Front Biosci , vol.10 , pp. 478-482
    • Rosenthal, K.S.1
  • 3
    • 32844465107 scopus 로고    scopus 로고
    • Ligand epitope antigen presentation system vaccines against herpes simplex virus
    • Goel N., Zimmerman D., Rosenthal K.S. Ligand epitope antigen presentation system vaccines against herpes simplex virus. Front Biosci 2005, 10:966-974.
    • (2005) Front Biosci , vol.10 , pp. 966-974
    • Goel, N.1    Zimmerman, D.2    Rosenthal, K.S.3
  • 4
    • 0029759944 scopus 로고    scopus 로고
    • A new approach to T cell activation: natural and synthetic conjugates capable of activating T cells
    • Zimmerman D.H., Bergmann K.F., Rosenthal K.S., Elliott D.A. A new approach to T cell activation: natural and synthetic conjugates capable of activating T cells. Vaccine Res 1996, 5:91-102.
    • (1996) Vaccine Res , vol.5 , pp. 91-102
    • Zimmerman, D.H.1    Bergmann, K.F.2    Rosenthal, K.S.3    Elliott, D.A.4
  • 5
    • 0029784256 scopus 로고    scopus 로고
    • Immunization with peptide heteroconjugates primes a TH1 associated antibody (IgG2a) response which recognize the native epitope on the 38kDa protein of Mycobacterium tuberculosis
    • Zimmerman D.H., Morris S., Rouse D., Worthington K.F.W., Elliott D.A., Rosenthal K.S. Immunization with peptide heteroconjugates primes a TH1 associated antibody (IgG2a) response which recognize the native epitope on the 38kDa protein of Mycobacterium tuberculosis. Vaccine Res 1996, 5:103-118.
    • (1996) Vaccine Res , vol.5 , pp. 103-118
    • Zimmerman, D.H.1    Morris, S.2    Rouse, D.3    Worthington, K.F.W.4    Elliott, D.A.5    Rosenthal, K.S.6
  • 6
    • 33646936414 scopus 로고    scopus 로고
    • The L.E.A.P.S. approach to vaccine development
    • Zimmerman D.H., Rosenthal K.S. The L.E.A.P.S. approach to vaccine development. Front Biosci 2005, 10:790-798.
    • (2005) Front Biosci , vol.10 , pp. 790-798
    • Zimmerman, D.H.1    Rosenthal, K.S.2
  • 7
    • 0016592110 scopus 로고
    • Effect of anti-beta-2-microglobulin on antigen and allogenic lymphocyte-induced proliferation of human lymphocytes
    • McCalmon R.T., Kubo R.T., Grey H.M. Effect of anti-beta-2-microglobulin on antigen and allogenic lymphocyte-induced proliferation of human lymphocytes. J Immunol 1975, 114:1766-1770.
    • (1975) J Immunol , vol.114 , pp. 1766-1770
    • McCalmon, R.T.1    Kubo, R.T.2    Grey, H.M.3
  • 8
    • 0033547872 scopus 로고    scopus 로고
    • Immunization with a L.E.A.P.S. heteroconjugate containing a CTL epitope and a peptide from beta-2-microglobulin elicits a protective and DTH response to herpes simplex virus type 1
    • Rosenthal K.S., Mao H., Horne W., Wright C., Zimmerman D. Immunization with a L.E.A.P.S. heteroconjugate containing a CTL epitope and a peptide from beta-2-microglobulin elicits a protective and DTH response to herpes simplex virus type 1. Vaccine 1999, 17:535-542.
    • (1999) Vaccine , vol.17 , pp. 535-542
    • Rosenthal, K.S.1    Mao, H.2    Horne, W.3    Wright, C.4    Zimmerman, D.5
  • 9
    • 0346186985 scopus 로고    scopus 로고
    • A L.E.A.P.S. heteroconjugate vaccine containing a T cell epitope from HSV-1 glycoprotein D elicits Th1 responses and protection
    • Goel N., Rong Q., Zimmerman D., Rosenthal K.S. A L.E.A.P.S. heteroconjugate vaccine containing a T cell epitope from HSV-1 glycoprotein D elicits Th1 responses and protection. Vaccine 2003, 21:4410-4420.
    • (2003) Vaccine , vol.21 , pp. 4410-4420
    • Goel, N.1    Rong, Q.2    Zimmerman, D.3    Rosenthal, K.S.4
  • 10
    • 41149180875 scopus 로고    scopus 로고
    • L.E.A.P.S. heteroconjugate is able to prevent and treat experimental autoimmune myocarditis by altering trafficking of autoaggressive cells to the heart
    • Cihakova D., Barin J.G., Baldeviano G.C., Talor M.V., Zimmerman D.H., Talor E., et al. L.E.A.P.S. heteroconjugate is able to prevent and treat experimental autoimmune myocarditis by altering trafficking of autoaggressive cells to the heart. Int Immunol 2008, 8:624-633.
    • (2008) Int Immunol , vol.8 , pp. 624-633
    • Cihakova, D.1    Barin, J.G.2    Baldeviano, G.C.3    Talor, M.V.4    Zimmerman, D.H.5    Talor, E.6
  • 11
    • 77949485280 scopus 로고    scopus 로고
    • CEL-2000: a therapeutic vaccine for rheumatoid arthritis arrests disease development and alters serum cytokine/chemokine patterns in the bovine collagen type II induced arthritis in the DBA mouse model
    • Zimmerman D.H., Taylor P., Bendele A., CArambula R., Duzant Y., Lowe V., et al. CEL-2000: a therapeutic vaccine for rheumatoid arthritis arrests disease development and alters serum cytokine/chemokine patterns in the bovine collagen type II induced arthritis in the DBA mouse model. Int Immunopharmacol 2010, 10:412-421.
    • (2010) Int Immunopharmacol , vol.10 , pp. 412-421
    • Zimmerman, D.H.1    Taylor, P.2    Bendele, A.3    CArambula, R.4    Duzant, Y.5    Lowe, V.6
  • 12
    • 0035860621 scopus 로고    scopus 로고
    • Induction of cross clade reactive antibodies in mice conjugates of HGP-30 peptide analog of HIV-1 (SF2 p17) and peptide segments of human beta-2-microglobulin or MHC II beta chain
    • Zimmerman D.H., Lloyd J.P., Heisey D., Winship M.D., Siwek M., Taylor E., et al. Induction of cross clade reactive antibodies in mice conjugates of HGP-30 peptide analog of HIV-1 (SF2 p17) and peptide segments of human beta-2-microglobulin or MHC II beta chain. Vaccine 2001, 19:4750-4759.
    • (2001) Vaccine , vol.19 , pp. 4750-4759
    • Zimmerman, D.H.1    Lloyd, J.P.2    Heisey, D.3    Winship, M.D.4    Siwek, M.5    Taylor, E.6
  • 13
    • 0000625869 scopus 로고
    • Analyzing tables of statistical tests
    • Rice W.B. Analyzing tables of statistical tests. Evolution 1989, 43:223-225.
    • (1989) Evolution , vol.43 , pp. 223-225
    • Rice, W.B.1
  • 14
    • 0026653220 scopus 로고
    • LPS activation of bone marrow natural suppressor cells
    • Holda J.H. LPS activation of bone marrow natural suppressor cells. Cell Immunol 1992, 141:518-527.
    • (1992) Cell Immunol , vol.141 , pp. 518-527
    • Holda, J.H.1
  • 15
    • 0026481133 scopus 로고
    • Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with agranulocytes macrophage stimulating factor
    • Inaba K., Inaba M., Romani N., Ava H., Deguchi M., Ikehara S., et al. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with agranulocytes macrophage stimulating factor. J Exp Med 1992, 176:1693-1702.
    • (1992) J Exp Med , vol.176 , pp. 1693-1702
    • Inaba, K.1    Inaba, M.2    Romani, N.3    Ava, H.4    Deguchi, M.5    Ikehara, S.6
  • 16
    • 52649109063 scopus 로고    scopus 로고
    • Stat 3 and Stat 5 dependent pathways competitively regulate the pan differentiation of CD 34 pos cells into tumor competent dendritic cells
    • Cohen P., Koski G., Czerniecki B., Bunting K., Fu X.-Y., Wang Z., et al. Stat 3 and Stat 5 dependent pathways competitively regulate the pan differentiation of CD 34 pos cells into tumor competent dendritic cells. Blood 2008, 112:1832-1843.
    • (2008) Blood , vol.112 , pp. 1832-1843
    • Cohen, P.1    Koski, G.2    Czerniecki, B.3    Bunting, K.4    Fu, X.-Y.5    Wang, Z.6
  • 17
    • 0345358584 scopus 로고    scopus 로고
    • The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses
    • Trinchieri G., Pflanz S., Kastelein R.A. The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses. Immunity 2003, 19:641-644.
    • (2003) Immunity , vol.19 , pp. 641-644
    • Trinchieri, G.1    Pflanz, S.2    Kastelein, R.A.3
  • 18
    • 0034332450 scopus 로고    scopus 로고
    • Generation of murine dendritic cells from flt3-ligand-supplemented bone marrow cultures
    • Brasel K., De Smedt T., Smith J.L., Maliszewski C.R. Generation of murine dendritic cells from flt3-ligand-supplemented bone marrow cultures. Blood 2000, 96:3029-3039.
    • (2000) Blood , vol.96 , pp. 3029-3039
    • Brasel, K.1    De Smedt, T.2    Smith, J.L.3    Maliszewski, C.R.4
  • 19
    • 0029661945 scopus 로고    scopus 로고
    • Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand0treated mice: multiple dendritic cell subpopulations identified
    • Maraskovsky E., Brasel K., Teepe M. Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand0treated mice: multiple dendritic cell subpopulations identified. J Exp Med 1996, 184:1953-1962.
    • (1996) J Exp Med , vol.184 , pp. 1953-1962
    • Maraskovsky, E.1    Brasel, K.2    Teepe, M.3
  • 20
    • 3042521047 scopus 로고    scopus 로고
    • Modulating Th1/Th2 responses with microbes, dendritic cells, and pathogen recognition receptors
    • Pulendran B. Modulating Th1/Th2 responses with microbes, dendritic cells, and pathogen recognition receptors. Immunol Res 2004, 29:187-196.
    • (2004) Immunol Res , vol.29 , pp. 187-196
    • Pulendran, B.1
  • 21
    • 40849140631 scopus 로고    scopus 로고
    • Effective treatment of spontaneous metastases derived from a poorly immunogenic murine mammary carcinoma by combined dendritic tumor hybrid vaccination and adoptive transfer of sensitized T cells
    • Tamai H., Watanabe S., Zheng R., Deguchi K., Cohen P.A., Koski G.K., et al. Effective treatment of spontaneous metastases derived from a poorly immunogenic murine mammary carcinoma by combined dendritic tumor hybrid vaccination and adoptive transfer of sensitized T cells. Clin Immunol 2008, 127:66-77.
    • (2008) Clin Immunol , vol.127 , pp. 66-77
    • Tamai, H.1    Watanabe, S.2    Zheng, R.3    Deguchi, K.4    Cohen, P.A.5    Koski, G.K.6
  • 22
    • 33645734929 scopus 로고    scopus 로고
    • Toll-dependent selection of microbial antigens for presentation by dendritic cells
    • Blander J.M., Medzhitov R. Toll-dependent selection of microbial antigens for presentation by dendritic cells. Nature 2006, 440:808-812.
    • (2006) Nature , vol.440 , pp. 808-812
    • Blander, J.M.1    Medzhitov, R.2
  • 23
    • 0031725838 scopus 로고    scopus 로고
    • High level IL-12 production by human DCs requires 2 signals
    • Snijders A., Kaliniski P., Hilkens C.M., Kaspenberg M.L. High level IL-12 production by human DCs requires 2 signals. Int Immunol 1998, 10(11):1593-1598.
    • (1998) Int Immunol , vol.10 , Issue.11 , pp. 1593-1598
    • Snijders, A.1    Kaliniski, P.2    Hilkens, C.M.3    Kaspenberg, M.L.4
  • 24
    • 49249128648 scopus 로고    scopus 로고
    • Paired TLR agonists enhance vaccine therapy through induction of IL-12
    • Zheng R., Cohen P.A., Paustian C., Johnson T.C., Lee W.T., Shu S., et al. Paired TLR agonists enhance vaccine therapy through induction of IL-12. Cancer Res 2008, 68(11):4045-4049.
    • (2008) Cancer Res , vol.68 , Issue.11 , pp. 4045-4049
    • Zheng, R.1    Cohen, P.A.2    Paustian, C.3    Johnson, T.C.4    Lee, W.T.5    Shu, S.6
  • 25
    • 23944489407 scopus 로고    scopus 로고
    • Selected toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
    • Napolitani G., Rinaldi A., Bertoni F., Sallusto F., Lazavecchia A. Selected toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat Immunol 2000, 6:769-776.
    • (2000) Nat Immunol , vol.6 , pp. 769-776
    • Napolitani, G.1    Rinaldi, A.2    Bertoni, F.3    Sallusto, F.4    Lazavecchia, A.5
  • 26
    • 0034670053 scopus 로고    scopus 로고
    • A subset of human monocyte-derived DCs expresses high levels of IL-12 in response to combines CD40L and IFN-gamma treatment
    • Mosca P.J., Hobeika A.C., Clay T.M., Nair S.K., Thomas E.K., Morse M.A., et al. A subset of human monocyte-derived DCs expresses high levels of IL-12 in response to combines CD40L and IFN-gamma treatment. Blood 2000, 96(10):3499-3504.
    • (2000) Blood , vol.96 , Issue.10 , pp. 3499-3504
    • Mosca, P.J.1    Hobeika, A.C.2    Clay, T.M.3    Nair, S.K.4    Thomas, E.K.5    Morse, M.A.6
  • 27
    • 0035339882 scopus 로고    scopus 로고
    • Differential production of IL-12, IFN-alpha, and IFN-gamma by mouse dendritic cell subsets
    • Hochrein H., Shortman K., Vremec D., Scott B., Hertzog P., O'Keefe M. Differential production of IL-12, IFN-alpha, and IFN-gamma by mouse dendritic cell subsets. J Immunol 2001, 166:5448-5455.
    • (2001) J Immunol , vol.166 , pp. 5448-5455
    • Hochrein, H.1    Shortman, K.2    Vremec, D.3    Scott, B.4    Hertzog, P.5    O'Keefe, M.6
  • 28
    • 33750282677 scopus 로고    scopus 로고
    • The IL-23/Th17 axis: therapeutic targets of autoimmune inflammation
    • Kikly K., Liu L., Na S., Sedgwick J.D. The IL-23/Th17 axis: therapeutic targets of autoimmune inflammation. Curr Opin Immunol 2006, 18:670-675.
    • (2006) Curr Opin Immunol , vol.18 , pp. 670-675
    • Kikly, K.1    Liu, L.2    Na, S.3    Sedgwick, J.D.4
  • 30
    • 0025733855 scopus 로고
    • The role of IL-10 in crossregulation of TH1 and TH2 responses
    • Mosmann T.R., Moore K.W. The role of IL-10 in crossregulation of TH1 and TH2 responses. Immunol Today 1991, 2:49-53.
    • (1991) Immunol Today , vol.2 , pp. 49-53
    • Mosmann, T.R.1    Moore, K.W.2
  • 31
    • 0025763807 scopus 로고
    • IL-10 acts on the antigen presenting cell to inhibit cytokine production by Th1 cells
    • Fiorentino D., Zlotnik A., Vieira P., Mosmann T., Howard M., Moore K., et al. IL-10 acts on the antigen presenting cell to inhibit cytokine production by Th1 cells. J Immunol 1991, 146:3444-3451.
    • (1991) J Immunol , vol.146 , pp. 3444-3451
    • Fiorentino, D.1    Zlotnik, A.2    Vieira, P.3    Mosmann, T.4    Howard, M.5    Moore, K.6
  • 32
    • 77955055508 scopus 로고    scopus 로고
    • IL-10 inhibits CD28 and ICOS costimulates of T cells via src homology 2 domain-containing protein tyrosine phosphotase 1
    • Taylor A., Akdis M., Joss A., Akkoc T., Wenig R., Colonna M., et al. IL-10 inhibits CD28 and ICOS costimulates of T cells via src homology 2 domain-containing protein tyrosine phosphotase 1. J Allergy Ashthma Res 2007, 12:76-83.
    • (2007) J Allergy Ashthma Res , vol.12 , pp. 76-83
    • Taylor, A.1    Akdis, M.2    Joss, A.3    Akkoc, T.4    Wenig, R.5    Colonna, M.6
  • 33
  • 34
    • 0032534684 scopus 로고    scopus 로고
    • Peptide modification of blocking of CD8, resulting in weak TCR signaling, can activate CTL for FAS-but not perforin-dependent cytotoxicity or cytokine production
    • Kessler B., Hudrisier D., Schroeter M., Tschopp J., Cerottini J.C., Luescher I.F. Peptide modification of blocking of CD8, resulting in weak TCR signaling, can activate CTL for FAS-but not perforin-dependent cytotoxicity or cytokine production. J Immunol 1998, 161:6939-6946.
    • (1998) J Immunol , vol.161 , pp. 6939-6946
    • Kessler, B.1    Hudrisier, D.2    Schroeter, M.3    Tschopp, J.4    Cerottini, J.C.5    Luescher, I.F.6
  • 35
    • 0030947317 scopus 로고    scopus 로고
    • Are CD8+ dendritic cells (DC) veto cells? The role of CD8 in DC development and in the regulation of CD4 and CD8 T cell responses
    • Kronin V., Vremec D., Winkel K., Classon B.J., Miller R.G., Mak T.W., et al. Are CD8+ dendritic cells (DC) veto cells? The role of CD8 in DC development and in the regulation of CD4 and CD8 T cell responses. Int Immunol 1997, 9:1061-1064.
    • (1997) Int Immunol , vol.9 , pp. 1061-1064
    • Kronin, V.1    Vremec, D.2    Winkel, K.3    Classon, B.J.4    Miller, R.G.5    Mak, T.W.6
  • 36
    • 0035070641 scopus 로고    scopus 로고
    • Differential effect of CD8+ and CD8-dendritic cells in the stimulation of secondary CD4+ T cells
    • Kronin V., Fitzmaurice C., Caminschi I., Shortman K., Jackson D., Brown L. Differential effect of CD8+ and CD8-dendritic cells in the stimulation of secondary CD4+ T cells. Int Immunol 2001, 13:465-473.
    • (2001) Int Immunol , vol.13 , pp. 465-473
    • Kronin, V.1    Fitzmaurice, C.2    Caminschi, I.3    Shortman, K.4    Jackson, D.5    Brown, L.6
  • 37
    • 0035433575 scopus 로고    scopus 로고
    • Dendritic cell subsets and costimulation for effector T-cell responses
    • Lane P., McConnell F. Dendritic cell subsets and costimulation for effector T-cell responses. Curr Opin Pharmacol 2001, 1:409-416.
    • (2001) Curr Opin Pharmacol , vol.1 , pp. 409-416
    • Lane, P.1    McConnell, F.2


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