Targeting Toll-like receptor 7/8 enhances uptake of apoptotic leukemic cells by monocyte-derived dendritic cells but interferes with subsequent cytokine-induced maturation

Cancer Immunology, Immunotherapy

Volumn 60, Issue 1, 2011, Pages 37-47

  Van Den Ancker, Willemijn ^a   Van Luijn, Marvin M ^a   Ruben, Jurjen M ^a   Westers, Theresia M ^a   Bontkes, Hetty J ^a   Ossenkoppele, Gert J ^a   De Gruijl, Tanja D ^a   Van De Loosdrecht, Arjan A ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Acute myeloid leukemia; Dendritic cell vaccination; Immunotherapy; Toll like receptors

Indexed keywords

INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 6; LEUKEMIA ANTIGEN; PROSTAGLANDIN E2; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CELL LYSATE; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; HEAT SHOCK; HUMAN; HUMAN CELL; LEUKEMIA CELL; LYMPHOCYTE ACTIVATION; MIXED LYMPHOCYTE REACTION; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTIGEN PRESENTATION; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; ANTIGENS, NEOPLASM; CANCER VACCINES; CELL MOVEMENT; CELLS, CULTURED; CYTOKINES; DENDRITIC CELLS; ENDOCYTOSIS; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; IMIDAZOLES; IMMUNOTHERAPY; LEUKEMIA, MYELOID, ACUTE; LYMPHOCYTE ACTIVATION; MONOCYTES; PEPTIDE FRAGMENTS; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8;

EID: 79953735244     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-010-0917-y     Document Type: Article

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