Characterization of four conventional dendritic cell subsets in human skin-draining lymph nodes in relation to T-cell activation

Blood

Volumn 118, Issue 9, 2011, Pages 2502-2510

  Van De Ven, Rieneke ^a   Van Den Hout, Mari F C M ^a   Lindenberg, Jelle J ^a   Sluijter, Berbel J R ^a   Van Leeuwen, Paul A M ^a   Lougheed, Sinéad M ^a   Meijer, Sybren ^a   Van Den Tol, M Petrousjka ^a   Scheper, Rik J ^a   De Gruijl, Tanja D ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD11 ANTIGEN; CD14 ANTIGEN; GAMMA INTERFERON; LANGERIN; UVOMORULIN;

ADULT; AGED; ARTICLE; CELL MATURATION; CELL MIGRATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; FEMALE; HUMAN; LANGERHANS CELL; MALE; MELANOMA; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENTINEL LYMPH NODE; SKIN CELL; T LYMPHOCYTE ACTIVATION;

EID: 80052406212     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-03-344838     Document Type: Article

References (50)

1. Whiteside T.L., Odoux C. Dendritic cell biology and cancer therapy. Cancer Immunol Immunother. 2004;53(3):240-248. (Pubitemid 38328047)
2. Lesterhuis W.J., Aarntzen E.H., De Vries I.J., et al. Dendritic cell vaccines in melanoma: From promise to proof? Crit Rev Oncol Hematol. 2008;66(2):118-134.
3. Fay J.W., Palucka A.K., Paczesny S., et al. Long-term outcomes in patients with metastatic melanoma vaccinated with melanoma peptide-pulsed CD34(+) progenitor-derived dendritic cells. Cancer Immunol Immunother. 2006;55(10):1209-1218. (Pubitemid 43992047)
4. Steinman R.M. Dendritic cells in vivo: A key target for a new vaccine science. Immunity. 2008;29(3):319-324.
5. Barratt-Boyes S.M., Figdor C.G. Current issues in delivering DCs for immunotherapy. Cytotherapy. 2004;6(2):105-110. (Pubitemid 38714806)
6. Figdor C.G., De Vries I.J., Lesterhuis W.J., Melief C.J. Dendritic cell immunotherapy: Mapping the way. Nat Med. 2004;10(5):475-480. (Pubitemid 38667904)
7. De Vries I.J., Adema G.J., Punt C.J., Figdor C.G. Phenotypical and functional characterization of clinical-grade dendritic cells. Methods Mol Med. 2005;109:113-126.
8. Merad M., Manz M.G. Dendritic cell homeostasis. Blood. 2009;113(15):3418-3427.
9. Jongbloed S.L., Kassianos A.J., McDonald K.J., et al. Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens. J Exp Med. 2010;207(6):1247-1260.
10. Bachem A., Guttler S., Hartung E., et al. Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells. J Exp Med. 2010;207(6):1273-1281.
11. Poulin L.F., Salio M., Griessinger E., et al. Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8{alpha}+ dendritic cells. J Exp Med. 2010;207(6):1261-1271.
12. Naik S.H. Demystifying the development of dendritic cell subtypes, a little. Immunol Cell Biol. 2008;86(5):439-452. (Pubitemid 351948216)
13. Pulendran B., Tang H., Denning T.L. Division of labor, plasticity, and crosstalk between dendritic cell subsets. Curr Opin Immunol. 2008;20(1):61-67.
14. Merad M., Ginhoux F., Collin M. Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cells. Nat Rev Immunol. 2008;8(12):935-947.
15. Angel C.E., Chen C.J., Horlacher O.C., et al. Distinctive localization of antigen-presenting cells in human lymph nodes. Blood. 2009;113(6):1257-1267.
16. Vuylsteke R.J., Van Leeuwen P.A., Meijer S., et al. Sampling tumor-draining lymph nodes for phenotypic and functional analysis of dendritic cells and T cells. Am J Pathol. 2002;161(1):19-26. (Pubitemid 34760766)
17. Elliott B., Cook M.G., John R.J., et al. Successful live cell harvest from bisected sentinel lymph nodes research report. J Immunol Methods. 2004;291(1-2):71-78. (Pubitemid 39164338)
18. Molenkamp B.G., Van Leeuwen P.A., Meijer S., et al. Intradermal CpG-B activates both plasmacytoid and myeloid dendritic cells in the sentinel lymph node of melanoma patients. Clin Cancer Res. 2007;13(10):2961-2969. (Pubitemid 46849571)
19. Molenkamp B.G., Sluijter B.J., Van Leeuwen P.A., et al. Local administration of PF-3512676 CpG-B instigates tumor-specific CD8+ T-cell reactivity in melanoma patients. Clin Cancer Res. 2008;14(14):4532-4542.
20. Vuylsteke R.J., Molenkamp B.G., Gietema H.A., et al. Local administration of granulocyte/macrophage colony-stimulating factor increases the number and activation state of dendritic cells in the sentinel lymph node of early-stage melanoma. Cancer Res. 2004;64(22):8456-8460. (Pubitemid 39491787)
21. Vuylsteke R.J., Molenkamp B.G., Van Leeuwen P.A., et al. Tumor-specific CD8+ T cell reactivity in the sentinel lymph node of GM-CSF-treated stage I melanoma patients is associated with high myeloid dendritic cell content. Clin Cancer Res. 2006;12(9):2826-2833.
22. Ginhoux F., Collin M.P., Bogunovic M., et al. Bloodderived dermal langerin+ dendritic cells survey the skin in the steady state. J Exp Med. 2007;204(13):3133-3146.
23. Poulin L.F., Henri S., De Bovis B., et al. The dermis contains langerin+ dendritic cells that develop and function independently of epidermal Langerhans cells. J Exp Med. 2007;204(13):3119-3131.
24. Bursch L.S., Wang L., Igyarto B., et al. Identification of a novel population of Langerin+ dendritic cells. J Exp Med. 2007;204(13):3147-3156.
25. Nagao K., Ginhoux F., Leitner W.W., et al. Murine epidermal Langerhans cells and langerin-expressing dermal dendritic cells are unrelated and exhibit distinct functions. Proc Natl Acad Sci U S A. 2009;106(9):3312-3317.
26. De Gruijl T.D., Luykx-de Bakker S.A., Tillman B.W., et al. Prolonged maturation and enhanced transduction of dendritic cells migrated from human skin explants after in situ delivery of CD40-targeted adenoviral vectors. J Immunol. 2002;169(9):5322-5331. (Pubitemid 35217206)
27. Ueta M., Kweon M.N., Sano Y., et al. Immunosuppressive properties of human amniotic membrane for mixed lymphocyte reaction. Clin Exp Immunol. 2002;129(3):464-470. (Pubitemid 35024915)
28. De Gruijl T.D., Sombroek C.C., Lougheed S.M., et al. A postmigrational switch among skin-derived dendritic cells to a macrophage-like phenotype is predetermined by the intracutaneous cytokine balance. J Immunol. 2006;176(12):7232-7242. (Pubitemid 43849023)
29. Nestle F.O., Di Meglio P., Qin J.Z., Nickoloff B.J. Skin immune sentinels in health and disease. Nat Rev Immunol. 2009;9(10):679-691.
30. Douillard P., Stoitzner P., Tripp C.H., et al. Mouse lymphoid tissue contains distinct subsets of langerin/CD207 dendritic cells, only one of which represents epidermal-derived Langerhans cells. J Invest Dermatol. 2005;125(5):983-994.
31. Flacher V., Douillard P., Ait-Yahia S., et al. Expression of langerin/CD207 reveals dendritic cell heterogeneity between inbred mouse strains. Immunology. 2008;123(3):339-347. (Pubitemid 351171198)
32. Laffont S., Siddiqui K.R., Powrie F. Intestinal inflammation abrogates the tolerogenic properties of MLN CD103+ dendritic cells. Eur J Immunol. 2010;40(7):1877-1883.
33. Bedoui S., Whitney P.G., Waithman J., et al. Crosspresentation of viral and self antigens by skinderived CD103+ dendritic cells. Nat Immunol. 2009;10(5):488-495.
34. Geissmann F., Manz M.G., Jung S., et al. Development of monocytes, macrophages, and dendritic cells. Science. 2010;327:656-661.
35. Klechevsky E., Liu M., Morita R., et al. Understanding human myeloid dendritic cell subsets for the rational design of novel vaccines. Hum Immunol. 2009;70(5):281-288.
36. Farrand K.J., Dickgreber N., Stoitzner P., et al. Langerin+ CD8alpha+ dendritic cells are critical for cross-priming and IL-12 production in response to systemic antigens. J Immunol. 2009;183(12):7732-7742.
37. McDonnell A.M., Prosser A.C., Van Bruggen I., Robinson B.W., Currie A.J. CD8alpha+ DC are not the sole subset cross-presenting cell-associated tumor antigens from a solid tumor. Eur J Immunol. 2010;40(6):1617-1627.
38. Molenkamp B.G., Vuylsteke R.J., Van Leeuwen P.A., et al. Matched skin and sentinel lymph node samples of melanoma patients reveal exclusive migration of mature dendritic cells. Am J Pathol. 2005;167(5):1301-1307. (Pubitemid 41541416)
39. Von Bubnoff D., Bausinger H., Matz H., et al. Human epidermal langerhans cells express the immunoregulatory enzyme indoleamine 2,3-dioxygenase. J Invest Dermatol. 2004(2):123:298-304.
40. Elnekave M., Furmanov K., Nudel I., et al. Directly transfected langerin+ dermal dendritic cells potentiate CD8+ T cell responses following intradermal plasmid DNA immunization. J Immunol. 2010;185(6):3463-3471
41. Romani N., Clausen B.E., Stoitzner P. Langerhans cells and more: Langerin-expressing dendritic cell subsets in the skin. Immunol Rev. 2010;234(1):120-141.
42. Angel C.E., Lala A., Chen C.J. et al. CD14+ antigen-presenting cells in human dermis are less mature than their CD1a+ counterparts. Int Immunol. 2007;19(11):1271-1279. (Pubitemid 47604728)
43. Zaba L.C., Krueger J.G., Lowes M.A. Resident and "inflammatory" dendritic cells in human skin. J Invest Dermatol. 2009;129(2):302-308.
44. Den Haan J.M., Lehar S.M., Bevan M.J. CD8(+) but not CD8(-) dendritic cells cross-prime cytotoxic T cells in vivo. J Exp Med. 2000;192(12):1685-1696.
45. Qiu C.H., Miyake Y., Kaise H., et al. Novel subset of CD8{alpha}+ dendritic cells localized in the marginal zone is responsible for tolerance to cell-associated antigens. J Immunol. 2009;182(7):4127-4136.
46. Robbins S.H., Walzer T., Dembele D., et al. Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling. Genome Biol. 2008;9(1):R17.
47. Contreras V., Urien C., Guiton R., et al. Existence of CD8alpha-like dendritic cells with a conserved functional specialization and a common molecular signature in distant mammalian species. J Immunol. 2010;185(6):3313-3325.
48. Crozat K., Guiton R., Contreras V., et al. The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8alpha+ dendritic cells. J Exp Med. 2010;207(6):1283-1292.
49. Gerlini G., Urso C., Mariotti G., et al. Plasmacytoid dendritic cells represent a major dendritic cell subset in sentinel lymph nodes of melanoma patients and accumulate in metastatic nodes. Clin Immunol. 2007;125(2):184-193. (Pubitemid 47562900)
50. Matteoli G., Mazzini E., Iliev I.D., et al. Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction. Gut. 2010;59(5):595-604.