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Volumn 113, Issue 9, 2009, Pages 1992-2002

Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: A novel mechanism of tumor-induced vasculogenesis

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN RECEPTOR; CD133 ANTIGEN; CD14 ANTIGEN; COLONY STIMULATING FACTOR 1; GREEN FLUORESCENT PROTEIN; PLEIOTROPHIN; PLEIOTROPHIN ANTIBODY; PROTEIN ANTIBODY; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2; VON WILLEBRAND FACTOR;

EID: 61849115658     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-02-133751     Document Type: Article
Times cited : (87)

References (67)
  • 1
    • 33750286135 scopus 로고    scopus 로고
    • The multifaceted circulating endothelial cell in cancer: Towards marker and target identification
    • Bertolini F, Shaked Y, Mancuso P, Kerbel RS. The multifaceted circulating endothelial cell in cancer: towards marker and target identification. Nat Rev Cancer. 2006;6:835-845.
    • (2006) Nat Rev Cancer , vol.6 , pp. 835-845
    • Bertolini, F.1    Shaked, Y.2    Mancuso, P.3    Kerbel, R.S.4
  • 2
    • 0033134604 scopus 로고    scopus 로고
    • Angiogenesis and vasculogenesis as therapeutic strategies for postnatal neovascularization
    • Isner JM, Asahara T. Angiogenesis and vasculogenesis as therapeutic strategies for postnatal neovascularization. J Clin Invest. 1999;103:1231-1236.
    • (1999) J Clin Invest , vol.103 , pp. 1231-1236
    • Isner, J.M.1    Asahara, T.2
  • 3
    • 0032528555 scopus 로고    scopus 로고
    • Evidence for circulating bone marrow-derived endothelial cells
    • Shi Q, Rafii S, Wu MH, et al. Evidence for circulating bone marrow-derived endothelial cells. Blood. 1998;92:362-367.
    • (1998) Blood , vol.92 , pp. 362-367
    • Shi, Q.1    Rafii, S.2    Wu, M.H.3
  • 4
    • 10044287079 scopus 로고    scopus 로고
    • Transplanted human bone marrow contributes to vascular endothelium
    • Jiang S, Walker L, Afentoulis M, et al. Transplanted human bone marrow contributes to vascular endothelium. Proc Natl Acad Sci U S A. 2004;101:16891-16896.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 16891-16896
    • Jiang, S.1    Walker, L.2    Afentoulis, M.3
  • 5
    • 20144388765 scopus 로고    scopus 로고
    • Circulating endothelial progenitor cells in multiple myeloma: Implications and significance
    • Zhang H, Vakil V, Braunstein M, et al. Circulating endothelial progenitor cells in multiple myeloma: implications and significance. Blood. 2005;105: 3286-3294.
    • (2005) Blood , vol.105 , pp. 3286-3294
    • Zhang, H.1    Vakil, V.2    Braunstein, M.3
  • 6
    • 38149006909 scopus 로고    scopus 로고
    • Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis
    • Gao D, Nolan DJ, Mellick AS, Bambino K, McDonnell K, Mittal V. Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis. Science. 2008;319:195-198.
    • (2008) Science , vol.319 , pp. 195-198
    • Gao, D.1    Nolan, D.J.2    Mellick, A.S.3    Bambino, K.4    McDonnell, K.5    Mittal, V.6
  • 7
    • 0037418213 scopus 로고    scopus 로고
    • Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors
    • Rehman J, Li J, Orschell CM, March KL. Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors. Circulation. 2003;107:1164-1169.
    • (2003) Circulation , vol.107 , pp. 1164-1169
    • Rehman, J.1    Li, J.2    Orschell, C.M.3    March, K.L.4
  • 8
    • 33748349659 scopus 로고    scopus 로고
    • Myeloid lineage progenitors give rise to vascular endothelium
    • Bailey AS, Willenbring H, Jiang S, et al. Myeloid lineage progenitors give rise to vascular endothelium. Proc Natl Acad Sci U SA. 2006;103:13156- 13161.
    • (2006) Proc Natl Acad Sci U SA , vol.103 , pp. 13156-13161
    • Bailey, A.S.1    Willenbring, H.2    Jiang, S.3
  • 9
    • 4644345036 scopus 로고    scopus 로고
    • Tumor-infiltrating dendritic cell precursors recruited by a beta-defensin contribute to vasculogenesis under the influence of Vegf-A
    • Conejo-Garcia JR, Benencia F, Courreges MC, et al. Tumor-infiltrating dendritic cell precursors recruited by a beta-defensin contribute to vasculogenesis under the influence of Vegf-A. Nat Med. 2004;10:950-958.
    • (2004) Nat Med , vol.10 , pp. 950-958
    • Conejo-Garcia, J.R.1    Benencia, F.2    Courreges, M.C.3
  • 10
    • 31044433663 scopus 로고    scopus 로고
    • Macrophages: Obligate partners for tumor cell migration, invasion, and metastasis
    • Condeelis J, Pollard JW. Macrophages: obligate partners for tumor cell migration, invasion, and metastasis. Cell. 2006;124:263-266.
    • (2006) Cell , vol.124 , pp. 263-266
    • Condeelis, J.1    Pollard, J.W.2
  • 11
    • 39149138136 scopus 로고    scopus 로고
    • Amacrophage gene expression signature defines a field effect in the lung tumor microenvironment
    • Stearman RS, Dwyer-Nield L, Grady MC, Malkinson AM, Geraci MW. Amacrophage gene expression signature defines a field effect in the lung tumor microenvironment. Cancer Res. 2008; 68:34-43.
    • (2008) Cancer Res , vol.68 , pp. 34-43
    • Stearman, R.S.1    Dwyer-Nield, L.2    Grady, M.C.3    Malkinson, A.M.4    Geraci, M.W.5
  • 12
    • 0032525099 scopus 로고    scopus 로고
    • Upregulation of pleiotrophin gene expression in developing microvasculature, macrophages, and astrocytes after acute ischemic brain injury
    • Yeh HJ, He YY, Xu J, Hsu CY, Deuel TF. Upregulation of pleiotrophin gene expression in developing microvasculature, macrophages, and astrocytes after acute ischemic brain injury. J Neurosci. 1998;18:3699-3707.
    • (1998) J Neurosci , vol.18 , pp. 3699-3707
    • Yeh, H.J.1    He, Y.Y.2    Xu, J.3    Hsu, C.Y.4    Deuel, T.F.5
  • 13
    • 20444407292 scopus 로고    scopus 로고
    • Pleiotrophin induces formation of functional neovasculature in vivo
    • Christman KL, Fang Q, Kim AJ, et al. Pleiotrophin induces formation of functional neovasculature in vivo. Biochem Biophys Res Commun. 2005;332:1146-1152.
    • (2005) Biochem Biophys Res Commun , vol.332 , pp. 1146-1152
    • Christman, K.L.1    Fang, Q.2    Kim, A.J.3
  • 14
    • 0029805056 scopus 로고    scopus 로고
    • Localization of pleiotrophin and its mRNA in subpopulations of neurons and their corresponding axonal tracts suggests important roles in neuralglial interactions during development and in maturity
    • Silos-Santiago I, Yeh HJ, Gurrieri MA, et al. Localization of pleiotrophin and its mRNA in subpopulations of neurons and their corresponding axonal tracts suggests important roles in neuralglial interactions during development and in maturity. J Neurobiol. 1996;31:283-296.
    • (1996) J Neurobiol , vol.31 , pp. 283-296
    • Silos-Santiago, I.1    Yeh, H.J.2    Gurrieri, M.A.3
  • 15
    • 0025615372 scopus 로고
    • Cloning and expression of a developmentally regulated protein that induces mitogenic and neurite outgrowth activity
    • Li YS, Milner PG, Chauhan AK, et al. Cloning and expression of a developmentally regulated protein that induces mitogenic and neurite outgrowth activity. Science. 1990;250:1690-1694.
    • (1990) Science , vol.250 , pp. 1690-1694
    • Li, Y.S.1    Milner, P.G.2    Chauhan, A.K.3
  • 16
    • 0032951527 scopus 로고    scopus 로고
    • Pleiotrophin and midkine, a family of mitogenic and angiogenic heparin-binding growth and differentiation factors
    • Zhang N, Deuel TF. Pleiotrophin and midkine, a family of mitogenic and angiogenic heparin-binding growth and differentiation factors. Curr Opin Hematol. 1999;6:44-650.
    • (1999) Curr Opin Hematol , vol.6 , pp. 44-650
    • Zhang, N.1    Deuel, T.F.2
  • 17
    • 34547486821 scopus 로고    scopus 로고
    • Secretion of pleiotrophin stimulates breast cancer progression through remodeling of the tumor microenvironment
    • Chang Y, Zuka M, Perez-Pinera P, et al. Secretion of pleiotrophin stimulates breast cancer progression through remodeling of the tumor microenvironment. Proc Natl Acad Sci U S A. 2007;104:10888-10893.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 10888-10893
    • Chang, Y.1    Zuka, M.2    Perez-Pinera, P.3
  • 18
    • 0028940896 scopus 로고
    • Differential expression of pleiotrophin and midkine in advanced neuroblastomas
    • Nakagawara A, Milbrandt J, Muramatsu T, et al. Differential expression of pleiotrophin and midkine in advanced neuroblastomas. Cancer Res. 1995;55:1792-1797.
    • (1995) Cancer Res , vol.55 , pp. 1792-1797
    • Nakagawara, A.1    Milbrandt, J.2    Muramatsu, T.3
  • 19
    • 0030878183 scopus 로고    scopus 로고
    • Human breast cancer growth inhibited in vivo by a dominant negative pleiotrophin mutant
    • Zhang N, Zhong R, Wang ZY, Deuel TF. Human breast cancer growth inhibited in vivo by a dominant negative pleiotrophin mutant. J Biol Chem. 1997;272:16733-16736.
    • (1997) J Biol Chem , vol.272 , pp. 16733-16736
    • Zhang, N.1    Zhong, R.2    Wang, Z.Y.3    Deuel, T.F.4
  • 20
    • 33645111064 scopus 로고    scopus 로고
    • Identification of the angiogenesis signaling domain in pleiotrophin defines a mechanism of the angiogenic switch
    • Zhang N, Zhong R, Perez-Pinera P, et al. Identification of the angiogenesis signaling domain in pleiotrophin defines a mechanism of the angiogenic switch. Biochem Biophys Res Commun. 2006;343:653-658.
    • (2006) Biochem Biophys Res Commun , vol.343 , pp. 653-658
    • Zhang, N.1    Zhong, R.2    Perez-Pinera, P.3
  • 21
    • 34347371570 scopus 로고    scopus 로고
    • Pleiotrophin is highly expressed by myeloma cells and promotes myeloma tumor growth
    • Chen H, Gordon MS, Campbell RA, et al. Pleiotrophin is highly expressed by myeloma cells and promotes myeloma tumor growth. Blood. 2007;110:287-295.
    • (2007) Blood , vol.110 , pp. 287-295
    • Chen, H.1    Gordon, M.S.2    Campbell, R.A.3
  • 22
    • 33646239174 scopus 로고    scopus 로고
    • Serum pleiotrophin levels are elevated in multiple myeloma patients and correlate with disease status
    • Yeh HS, Chen H, Manyak SJ, et al. Serum pleiotrophin levels are elevated in multiple myeloma patients and correlate with disease status. Br J Haematol. 2006;133:526-529.
    • (2006) Br J Haematol , vol.133 , pp. 526-529
    • Yeh, H.S.1    Chen, H.2    Manyak, S.J.3
  • 23
    • 18344389157 scopus 로고    scopus 로고
    • Serum levels of the angiogenic factor pleiotrophin in relation to disease stage in lung cancer patients
    • Jäger R, List B, Knabbe C, et al. Serum levels of the angiogenic factor pleiotrophin in relation to disease stage in lung cancer patients. Br J Cancer. 2002;86:858-863.
    • (2002) Br J Cancer , vol.86 , pp. 858-863
    • Jäger, R.1    List, B.2    Knabbe, C.3
  • 24
    • 0032494487 scopus 로고    scopus 로고
    • Relationship between serum concentrations of the growth factor pleiotrophin and pleiotrophin-positive tumors
    • Souttou B, Juhl H, Hackenbruck J, et al. Relationship between serum concentrations of the growth factor pleiotrophin and pleiotrophin-positive tumors. J Natl Cancer Inst. 1998;90:1468-1473.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1468-1473
    • Souttou, B.1    Juhl, H.2    Hackenbruck, J.3
  • 25
    • 14644395513 scopus 로고    scopus 로고
    • Ribozyme targeting of the growth factor pleiotrophin in established tumors: A gene therapy approach
    • Malerczyk C, Schulte AM, Czubayko F, et al. Ribozyme targeting of the growth factor pleiotrophin in established tumors: a gene therapy approach. Gene Ther. 2005;12:339-346.
    • (2005) Gene Ther , vol.12 , pp. 339-346
    • Malerczyk, C.1    Schulte, A.M.2    Czubayko, F.3
  • 26
    • 33746267422 scopus 로고    scopus 로고
    • RNA interference-mediated gene silencing of pleiotrophin through polyethylenimine-complexed small interfering RNAs in vivo exerts antitumoral effects in glioblastoma xenografts
    • Grzelinski M, Urban-Klein B, Martens T, et al. RNA interference-mediated gene silencing of pleiotrophin through polyethylenimine-complexed small interfering RNAs in vivo exerts antitumoral effects in glioblastoma xenografts. Hum Gene Ther. 2006;17:751-766.
    • (2006) Hum Gene Ther , vol.17 , pp. 751-766
    • Grzelinski, M.1    Urban-Klein, B.2    Martens, T.3
  • 27
    • 32944463899 scopus 로고    scopus 로고
    • Angiogenesis
    • Folkman J. Angiogenesis. Annu Rev Med. 2006;57:1-18.
    • (2006) Annu Rev Med , vol.57 , pp. 1-18
    • Folkman, J.1
  • 28
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med. 2003;9:669-676.
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 29
    • 33947310737 scopus 로고    scopus 로고
    • Inhibition of VEGF signaling pathways in multiple myeloma and other malignancies
    • Podar K, Anderson KC. Inhibition of VEGF signaling pathways in multiple myeloma and other malignancies. Cell Cycle. 2007;6:538-542.
    • (2007) Cell Cycle , vol.6 , pp. 538-542
    • Podar, K.1    Anderson, K.C.2
  • 30
    • 61849092466 scopus 로고    scopus 로고
    • Anti-VEGF antibody treatment markedly inhibits tumor growth in SCID-hu models of human multiple myeloma [abstract]
    • Campbell RA, Sanchez E, Chen H, et al. Anti-VEGF antibody treatment markedly inhibits tumor growth in SCID-hu models of human multiple myeloma [abstract]. Blood. 2006;108:846a.
    • (2006) Blood , vol.108
    • Campbell, R.A.1    Sanchez, E.2    Chen, H.3
  • 31
    • 0023771429 scopus 로고
    • Effects of granulocyte-macrophage colony-stimulating factor and colony-stimulating factor-1 on the proliferation and differentiation of murine alveolar macrophages
    • Akagawa KS, Kamoshita K, Tokunaga T. Effects of granulocyte-macrophage colony-stimulating factor and colony-stimulating factor-1 on the proliferation and differentiation of murine alveolar macrophages. J Immunol. 1988;141:3383-3390.
    • (1988) J Immunol , vol.141 , pp. 3383-3390
    • Akagawa, K.S.1    Kamoshita, K.2    Tokunaga, T.3
  • 32
    • 0031050397 scopus 로고    scopus 로고
    • Macrophage colony-stimulating factor gene transduction into human lung cancer cells differentially regulates metastasis formations in various organ microenvironments of natural killer cell-depleted SCID mice
    • Yano S, Nishioka Y, Nokihara H, Sone S. Macrophage colony-stimulating factor gene transduction into human lung cancer cells differentially regulates metastasis formations in various organ microenvironments of natural killer cell-depleted SCID mice. Cancer Res. 1997;57:784-790.
    • (1997) Cancer Res , vol.57 , pp. 784-790
    • Yano, S.1    Nishioka, Y.2    Nokihara, H.3    Sone, S.4
  • 33
    • 0037962287 scopus 로고    scopus 로고
    • MCSF expression is induced in healing myocardial infarcts and may regulate monocyte and endothelial cell phenotype
    • Frangogiannis NG, Mendoza LH, Ren G, et al. MCSF expression is induced in healing myocardial infarcts and may regulate monocyte and endothelial cell phenotype. Am J Physiol Heart Circ Physiol. 2003;285:H483-H492.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • Frangogiannis, N.G.1    Mendoza, L.H.2    Ren, G.3
  • 34
    • 20444422949 scopus 로고    scopus 로고
    • Macrophage colony-stimulating factor induces vascular endothelial growth factor production in skeletal muscle and promotes tumor angiogenesis
    • Okazaki T, Ebihara S, Takahashi H,Asada M, Kanda A, Sasaki H. Macrophage colony-stimulating factor induces vascular endothelial growth factor production in skeletal muscle and promotes tumor angiogenesis. J Immunol. 2005;174:7531-7538.
    • (2005) J Immunol , vol.174 , pp. 7531-7538
    • Okazaki, T.1    Ebihara, S.2    Takahashi, H.3    Asada, M.4    Kanda, A.5    Sasaki, H.6
  • 35
    • 3142753475 scopus 로고    scopus 로고
    • Cell fusion-independent differentiation of neural stem cells to the endothelial lineage
    • Wurmser AE, Nakashima K, Summers RG, et al. Cell fusion-independent differentiation of neural stem cells to the endothelial lineage. Nature. 2004;430:350-356.
    • (2004) Nature , vol.430 , pp. 350-356
    • Wurmser, A.E.1    Nakashima, K.2    Summers, R.G.3
  • 36
    • 26844551297 scopus 로고    scopus 로고
    • Transdifferentiation of mesenchymal stem cells into cardiomyocytes by direct cell-to-cell contact with neonatal cardiomyocyte but not adult cardiomyocytes
    • Yoon J, Shim WJ, Ro YM, Lim DS. Transdifferentiation of mesenchymal stem cells into cardiomyocytes by direct cell-to-cell contact with neonatal cardiomyocyte but not adult cardiomyocytes. Ann Hematol. 2005;84:715-721.
    • (2005) Ann Hematol , vol.84 , pp. 715-721
    • Yoon, J.1    Shim, W.J.2    Ro, Y.M.3    Lim, D.S.4
  • 38
    • 22944465060 scopus 로고    scopus 로고
    • Pleiotrophin cellular localization in nerve regeneration after peripheral nerve injury
    • Blondet B, Carpentier G, Lafdil F, Courty J. Pleiotrophin cellular localization in nerve regeneration after peripheral nerve injury. J Histochem Cytochem. 2005;53:971-977.
    • (2005) J Histochem Cytochem , vol.53 , pp. 971-977
    • Blondet, B.1    Carpentier, G.2    Lafdil, F.3    Courty, J.4
  • 39
    • 4344701270 scopus 로고    scopus 로고
    • Optimization of human T-cell expansion ex vivo using magnetic beads conjugated with anti-CD3 and Anti-CD28 antibodies
    • Kalamasz D, Long SA, Taniguchi R, Buckner JH, Berenson RJ, Bonyhadi M. Optimization of human T-cell expansion ex vivo using magnetic beads conjugated with anti-CD3 and Anti-CD28 antibodies. J Immunother. 2004;27:405-418.
    • (2004) J Immunother , vol.27 , pp. 405-418
    • Kalamasz, D.1    Long, S.A.2    Taniguchi, R.3    Buckner, J.H.4    Berenson, R.J.5    Bonyhadi, M.6
  • 40
    • 33747121704 scopus 로고    scopus 로고
    • LAG-lambda-1: A clinically relevant drug resistant human multiple myeloma tumor murine model that enables rapid evaluation of treatments for multiple myeloma
    • Campbell RA, Manyak SJ, Yang HH, et al. LAG-lambda-1: a clinically relevant drug resistant human multiple myeloma tumor murine model that enables rapid evaluation of treatments for multiple myeloma. Int J Oncol. 2006;28:1409-1417.
    • (2006) Int J Oncol , vol.28 , pp. 1409-1417
    • Campbell, R.A.1    Manyak, S.J.2    Yang, H.H.3
  • 41
    • 0030575911 scopus 로고    scopus 로고
    • Emmert-Buck MR, Bonner RF, Smith PD, et al. Laser capture microdissection. Science. 1996;274:998-1001.
    • Emmert-Buck MR, Bonner RF, Smith PD, et al. Laser capture microdissection. Science. 1996;274:998-1001.
  • 43
    • 1542471167 scopus 로고
    • Alu polymerase chain reaction: A method for rapid isolation of human-specific sequences from complex DNA sources
    • Nelson DL, Ledbetter SA, Corbo L, et al. Alu polymerase chain reaction: a method for rapid isolation of human-specific sequences from complex DNA sources. Proc Natl Acad Sci USA. 1989;86:6686-6690.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 6686-6690
    • Nelson, D.L.1    Ledbetter, S.A.2    Corbo, L.3
  • 44
    • 0036704390 scopus 로고    scopus 로고
    • Stem cell properties of human dental pulp stem cells
    • Gronthos S, Brahim J, Li W, et al. Stem cell properties of human dental pulp stem cells. J Dent Res. 2002;81:531-535.
    • (2002) J Dent Res , vol.81 , pp. 531-535
    • Gronthos, S.1    Brahim, J.2    Li, W.3
  • 45
    • 0037687418 scopus 로고    scopus 로고
    • SHED: Stem cells from human exfoliated deciduous teeth
    • Miura M, Gronthos S, Zhao M, et al. SHED: stem cells from human exfoliated deciduous teeth. Proc Natl Acad Sci USA. 2003;100:5807-5812.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 5807-5812
    • Miura, M.1    Gronthos, S.2    Zhao, M.3
  • 46
    • 34249979533 scopus 로고    scopus 로고
    • Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer
    • Venneri MA, De Palma M, Ponzoni M, et al. Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer. Blood. 2007;109:5276-5285.
    • (2007) Blood , vol.109 , pp. 5276-5285
    • Venneri, M.A.1    De Palma, M.2    Ponzoni, M.3
  • 47
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med. 2004;350:2335-2342.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 48
    • 37549040613 scopus 로고    scopus 로고
    • Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
    • Miller K, Wang M, Gralow J, et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med. 2007;357:2666-2676.
    • (2007) N Engl J Med , vol.357 , pp. 2666-2676
    • Miller, K.1    Wang, M.2    Gralow, J.3
  • 49
    • 34547856611 scopus 로고    scopus 로고
    • Systemic inhibition of tumour angiogenesis by endothelial cell-based gene therapy
    • Dudek AZ, Bodempudi V, Welsh BW, et al. Systemic inhibition of tumour angiogenesis by endothelial cell-based gene therapy. Br J Cancer. 2007;97:513-522.
    • (2007) Br J Cancer , vol.97 , pp. 513-522
    • Dudek, A.Z.1    Bodempudi, V.2    Welsh, B.W.3
  • 50
    • 33745020251 scopus 로고    scopus 로고
    • Pleiotrophin induces transdifferentiation of monocytes into functional endothelial cells
    • Sharifi BG, Zeng Z, Wang L, et al. Pleiotrophin induces transdifferentiation of monocytes into functional endothelial cells. Arterioscler Thromb Vasc Biol. 2006;26:1273-1280.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1273-1280
    • Sharifi, B.G.1    Zeng, Z.2    Wang, L.3
  • 51
    • 20144386931 scopus 로고    scopus 로고
    • Contribution of bone marrow-derived endothelial cells to human tumor vasculature
    • Peters BA, Diaz LA, Polyak K, et al. Contribution of bone marrow-derived endothelial cells to human tumor vasculature. Nat Med. 2005;11:261-262.
    • (2005) Nat Med , vol.11 , pp. 261-262
    • Peters, B.A.1    Diaz, L.A.2    Polyak, K.3
  • 52
    • 33750359173 scopus 로고    scopus 로고
    • PRL-3 initiates tumor angiogenesis by recruiting endothelial cells in vitro and in vivo
    • Guo K, Li J, Wang H, et al. PRL-3 initiates tumor angiogenesis by recruiting endothelial cells in vitro and in vivo. Cancer Res. 2006;66:9625-9635.
    • (2006) Cancer Res , vol.66 , pp. 9625-9635
    • Guo, K.1    Li, J.2    Wang, H.3
  • 53
    • 33644770150 scopus 로고    scopus 로고
    • Neoplastic circulating endothelial cells in multiple myeloma with 13q14 deletion
    • Rigolin GM, Fraulini C, Ciccone M, et al. Neoplastic circulating endothelial cells in multiple myeloma with 13q14 deletion. Blood. 2006;107:2531-2535.
    • (2006) Blood , vol.107 , pp. 2531-2535
    • Rigolin, G.M.1    Fraulini, C.2    Ciccone, M.3
  • 54
    • 14044271973 scopus 로고    scopus 로고
    • Transcriptional regulation of vascular endothelial growth factor in cancer
    • Loureiro RM, D'Amore PA. Transcriptional regulation of vascular endothelial growth factor in cancer. Cytokine Growth Factor Rev. 2005;16:77-89.
    • (2005) Cytokine Growth Factor Rev , vol.16 , pp. 77-89
    • Loureiro, R.M.1    D'Amore, P.A.2
  • 55
    • 0032952010 scopus 로고    scopus 로고
    • Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal
    • Benjamin LE, Golijanin D, Itin A, Pode D, Keshet E. Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal. J Clin Invest. 1999;103:159-165.
    • (1999) J Clin Invest , vol.103 , pp. 159-165
    • Benjamin, L.E.1    Golijanin, D.2    Itin, A.3    Pode, D.4    Keshet, E.5
  • 56
    • 0347133261 scopus 로고    scopus 로고
    • The role of CSF-1 in normal physiology of mammary gland and breast cancer: An update
    • Sapi E. The role of CSF-1 in normal physiology of mammary gland and breast cancer: an update. Exp Biol Med (Maywood). 2004;229:1-11.
    • (2004) Exp Biol Med (Maywood) , vol.229 , pp. 1-11
    • Sapi, E.1
  • 57
    • 0035911221 scopus 로고    scopus 로고
    • Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy
    • Lin EY, Nguyen AV, Russell RG, Pollard JW. Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J Exp Med. 2001;193:727-740.
    • (2001) J Exp Med , vol.193 , pp. 727-740
    • Lin, E.Y.1    Nguyen, A.V.2    Russell, R.G.3    Pollard, J.W.4
  • 58
    • 0041929158 scopus 로고    scopus 로고
    • M-CSF induces vascular endothelial growth factor production and angiogenic activity from human monocytes
    • Eubank TD, Galloway M, Montague CM, Waldman WJ, Marsh CB. M-CSF induces vascular endothelial growth factor production and angiogenic activity from human monocytes. J Immunol. 2003;171:2637-2643.
    • (2003) J Immunol , vol.171 , pp. 2637-2643
    • Eubank, T.D.1    Galloway, M.2    Montague, C.M.3    Waldman, W.J.4    Marsh, C.B.5
  • 59
    • 39649083396 scopus 로고    scopus 로고
    • FGFR-1 regulates angiogenesis through cytokines interleukin-4 and pleiotrophin
    • Magnusson PU, Dimberg A, Mellberg S, Lukinius A, Claesson-Welsh L. FGFR-1 regulates angiogenesis through cytokines interleukin-4 and pleiotrophin. Blood. 2007;110:4214-4222.
    • (2007) Blood , vol.110 , pp. 4214-4222
    • Magnusson, P.U.1    Dimberg, A.2    Mellberg, S.3    Lukinius, A.4    Claesson-Welsh, L.5
  • 60
    • 0030904197 scopus 로고    scopus 로고
    • An angiogenic role for the neurokines midkine and pleiotrophin in tumorigenesis
    • Choudhuri R, Zhang HT, Donnini S, Ziche M, Bicknell R. An angiogenic role for the neurokines midkine and pleiotrophin in tumorigenesis. Cancer Res. 1997;57:1814-1819.
    • (1997) Cancer Res , vol.57 , pp. 1814-1819
    • Choudhuri, R.1    Zhang, H.T.2    Donnini, S.3    Ziche, M.4    Bicknell, R.5
  • 61
    • 37549023012 scopus 로고    scopus 로고
    • Pleiotrophin, a multifunctional tumor promoter through induction of tumor angiogenesis, remodeling of the tumor microenvironment, and activation of stromal fibroblasts
    • Perez-Pinera P, Chang Y, Deuel TF. Pleiotrophin, a multifunctional tumor promoter through induction of tumor angiogenesis, remodeling of the tumor microenvironment, and activation of stromal fibroblasts. Cell Cycle. 2007;6:2877-2883.
    • (2007) Cell Cycle , vol.6 , pp. 2877-2883
    • Perez-Pinera, P.1    Chang, Y.2    Deuel, T.F.3
  • 62
    • 33744963068 scopus 로고    scopus 로고
    • PTEN deletion leads to up-regulation of a secreted growth factor pleiotrophin
    • Li G, Hu Y, Huo Y, et al. PTEN deletion leads to up-regulation of a secreted growth factor pleiotrophin. J Biol Chem. 2006;281:10663-10668.
    • (2006) J Biol Chem , vol.281 , pp. 10663-10668
    • Li, G.1    Hu, Y.2    Huo, Y.3
  • 63
    • 0036529988 scopus 로고    scopus 로고
    • Macrophage colony stimulating factor modulates the development of hematopoiesis by stimulating the differentiation of endothelial cells in the AGM region
    • Minehata K, Mukouyama YS, Sekiguchi T, Hara T, Miyajima A. Macrophage colony stimulating factor modulates the development of hematopoiesis by stimulating the differentiation of endothelial cells in the AGM region. Blood. 2002;99:2360-2368.
    • (2002) Blood , vol.99 , pp. 2360-2368
    • Minehata, K.1    Mukouyama, Y.S.2    Sekiguchi, T.3    Hara, T.4    Miyajima, A.5
  • 64
    • 33344467123 scopus 로고    scopus 로고
    • VEGF function in vascular pathogenesis
    • Ng YS, Krilleke D, Shima DT. VEGF function in vascular pathogenesis. Exp Cell Res. 2006;312:527-537.
    • (2006) Exp Cell Res , vol.312 , pp. 527-537
    • Ng, Y.S.1    Krilleke, D.2    Shima, D.T.3
  • 65
    • 20744445377 scopus 로고    scopus 로고
    • Gene expression profile in corneal neovascularization identified by immunology related macroarray
    • Usui T, Yamagami S, Yokoo S, Mimura T, Ono K, Amano S. Gene expression profile in corneal neovascularization identified by immunology related macroarray. Mol Vis. 2004;10:832-836.
    • (2004) Mol Vis , vol.10 , pp. 832-836
    • Usui, T.1    Yamagami, S.2    Yokoo, S.3    Mimura, T.4    Ono, K.5    Amano, S.6
  • 66
    • 0038692859 scopus 로고    scopus 로고
    • Endothelial progenitor cells: Isolation and characterization
    • Hristov M, Erl W, Weber PC. Endothelial progenitor cells: isolation and characterization. Trends Cardiovasc Med. 2003;13:201-206.
    • (2003) Trends Cardiovasc Med , vol.13 , pp. 201-206
    • Hristov, M.1    Erl, W.2    Weber, P.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.