Atm-deficient mice exhibit increased sensitivity to dextran sulfate sodium-induced colitis characterized by elevated DNA damage and persistent immune activation

Cancer Research

Volumn 70, Issue 5, 2010, Pages 1875-1884

  Westbrook, Aya M ^b   Schiestl, Robert H ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; 8 HYDROXYGUANINE; ATM PROTEIN; CD69 ANTIGEN; DEXTRAN SULFATE; DOUBLE STRANDED DNA; GAMMA INTERFERON; HERMES ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 4; NITROGEN; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD; COLITIS; CONTROLLED STUDY; DESCENDING COLON; DISEASE ACTIVITY; DISEASE MODEL; DNA DAMAGE; DNA STRAND BREAKAGE; ERYTHROBLAST; GENETIC SUSCEPTIBILITY; GENOMIC INSTABILITY; GENOTOXICITY; HETEROZYGOTE; HOMEOSTASIS; IMMUNE RESPONSE; IMMUNOPATHOGENESIS; IMMUNOREACTIVITY; IMMUNOREGULATION; LEUKOCYTE; MICRONUCLEUS; MOUSE; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REMISSION; T LYMPHOCYTE ACTIVATION; UPREGULATION; WILD TYPE;

ANIMALS; CELL CYCLE PROTEINS; COLITIS; COLON; CYTOKINES; DEXTRAN SULFATE; DNA DAMAGE; DNA-BINDING PROTEINS; GUANINE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PROTEIN-SERINE-THREONINE KINASES; T-LYMPHOCYTES; TUMOR SUPPRESSOR PROTEINS;

EID: 77950249024     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-2584     Document Type: Article

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