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Volumn 85, Issue 12, 2005, Pages 1471-1480

ATM deficiency induces oxidative stress and endoplasmic reticulum stress in astrocytes

Author keywords

Astrocyte; Ataxia telangiectasia mutated; Cerebellar Bergmann glia; Endoplasmic reticulum stress; Extracellular signal regulated protein kinases; Oxidative stress

Indexed keywords

ATM PROTEIN; CASPASE 12; COPPER; HEAT SHOCK PROTEIN 70; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE; SUPEROXIDE DISMUTASE; ZINC;

EID: 27944476980     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.3700354     Document Type: Article
Times cited : (81)

References (63)
  • 1
    • 0035449355 scopus 로고    scopus 로고
    • Cell cycle checkpoint signaling through the ATM and ATR kinases
    • Abraham RT. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev 2001;15:2177-2196.
    • (2001) Genes Dev , vol.15 , pp. 2177-2196
    • Abraham, R.T.1
  • 2
    • 0036012789 scopus 로고    scopus 로고
    • ATM deficiency and oxidative stress: A new dimension of defective response to DNA damage
    • Amsterdam
    • Barzilai A, Rotman G, Shiloh Y. ATM deficiency and oxidative stress: a new dimension of defective response to DNA damage. DNA Repair (Amsterdam) 2002;1:3-25.
    • (2002) DNA Repair , vol.1 , pp. 3-25
    • Barzilai, A.1    Rotman, G.2    Shiloh, Y.3
  • 3
    • 4444339751 scopus 로고    scopus 로고
    • ATM and ataxia telangiectasia
    • McKinnon PJ. ATM and ataxia telangiectasia. EMBO Rep 2004;5:772-776.
    • (2004) EMBO Rep , vol.5 , pp. 772-776
    • McKinnon, P.J.1
  • 4
    • 0035253615 scopus 로고    scopus 로고
    • ATM and ATR: Networking cellular responses to DNA damage
    • Shiloh Y. ATM and ATR: networking cellular responses to DNA damage. Curr Opin Genet Dev 2001;11:71-77.
    • (2001) Curr Opin Genet Dev , vol.11 , pp. 71-77
    • Shiloh, Y.1
  • 5
    • 7244250309 scopus 로고    scopus 로고
    • Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells
    • Ito K, Hirao A, Arai F, et al. Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells. Nature 2004;431:997-1002.
    • (2004) Nature , vol.431 , pp. 997-1002
    • Ito, K.1    Hirao, A.2    Arai, F.3
  • 6
    • 0033578411 scopus 로고    scopus 로고
    • Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs
    • USA
    • Barlow C, Dennery PA, Shigenaga MK, et al. Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs. Proc Natl Acad Sci USA 1999;96:9915-9919.
    • (1999) Proc Natl Acad Sci , vol.96 , pp. 9915-9919
    • Barlow, C.1    Dennery, P.A.2    Shigenaga, M.K.3
  • 7
    • 0035266308 scopus 로고    scopus 로고
    • Increased oxidative stress in ataxia telangiectasia evidenced by alterations in redox state of brains from Atm-deficient mice
    • Kamsler A, Daily D, Hochman A, et al. Increased oxidative stress in ataxia telangiectasia evidenced by alterations in redox state of brains from Atm-deficient mice. Cancer Res 2001;61:1849-1854.
    • (2001) Cancer Res , vol.61 , pp. 1849-1854
    • Kamsler, A.1    Daily, D.2    Hochman, A.3
  • 8
    • 1542500475 scopus 로고    scopus 로고
    • Treatment with a catalytic antioxidant corrects the neuro-behavioral defect in ataxia-telangiectasia mice
    • Browne SE, Roberts II LJ, Dennery PA, et al. Treatment with a catalytic antioxidant corrects the neuro-behavioral defect in ataxia-telangiectasia mice. Free Radic Biol Med 2004;36:938-942.
    • (2004) Free Radic Biol Med , vol.36 , pp. 938-942
    • Browne, S.E.1    Roberts, I.I.L.J.2    Dennery, P.A.3
  • 9
    • 0347479231 scopus 로고    scopus 로고
    • Oxidative stress is responsible for deficient survival and dendritogenesis in Purkinje neurons from ataxia-telangiectasia mutated mutant mice
    • Chen P, Peng C, Luff J, et al. Oxidative stress is responsible for deficient survival and dendritogenesis in Purkinje neurons from ataxia-telangiectasia mutated mutant mice. J Neurosci 2003;23:11453-11460.
    • (2003) J Neurosci , vol.23 , pp. 11453-11460
    • Chen, P.1    Peng, C.2    Luff, J.3
  • 10
    • 0035011079 scopus 로고    scopus 로고
    • Superoxide stress identifies neurons at risk in a model of ataxia-telangiectasia
    • Quick KL, Dugan LL. Superoxide stress identifies neurons at risk in a model of ataxia-telangiectasia. Ann Neurol 2001;49:627-635.
    • (2001) Ann Neurol , vol.49 , pp. 627-635
    • Quick, K.L.1    Dugan, L.L.2
  • 11
    • 0142123580 scopus 로고    scopus 로고
    • Late degeneration of nigro-striatal neurons in ATM-/- mice
    • Eilam R, Peter Y, Groner Y, et al. Late degeneration of nigro-striatal neurons in ATM-/- mice. Neuroscience 2003;121:83-98.
    • (2003) Neuroscience , vol.121 , pp. 83-98
    • Eilam, R.1    Peter, Y.2    Groner, Y.3
  • 12
    • 0030730292 scopus 로고    scopus 로고
    • Degeneration of neurons, synapses, and neuropil and glial activation in a murine Atm knockout model of ataxia-telangiectasia
    • Kuljis RO, Xu Y, Aguila MC, et al. Degeneration of neurons, synapses, and neuropil and glial activation in a murine Atm knockout model of ataxia-telangiectasia. Proc Natl Acad Sci 1997;94:12688-12693.
    • (1997) Proc Natl Acad Sci , vol.94 , pp. 12688-12693
    • Kuljis, R.O.1    Xu, Y.2    Aguila, M.C.3
  • 13
    • 14944346310 scopus 로고    scopus 로고
    • Loss of neuronal cell cycle control in ataxia-telangiectasia: A unified disesase mechanism
    • Yang Y, Herrup K. Loss of neuronal cell cycle control in ataxia-telangiectasia: a unified disesase mechanism. J Neurosci 2005;15:2522-2529.
    • (2005) J Neurosci , vol.15 , pp. 2522-2529
    • Yang, Y.1    Herrup, K.2
  • 14
    • 0034977186 scopus 로고    scopus 로고
    • Astrocytes protect neurons from nitric oxide toxicity by a glutathione-dependent mechanism
    • Chen Y, Vartiainen NE, Ying W, et al. Astrocytes protect neurons from nitric oxide toxicity by a glutathione-dependent mechanism. J Neurochem 2001;77:1601-1610.
    • (2001) J Neurochem , vol.77 , pp. 1601-1610
    • Chen, Y.1    Vartiainen, N.E.2    Ying, W.3
  • 15
    • 0029990439 scopus 로고    scopus 로고
    • Astrocytes protect neurons from hydrogen peroxide toxicity
    • Desagher S, Glowinski J, Premont J. Astrocytes protect neurons from hydrogen peroxide toxicity. J Neurosci 1996;16:2553-2562.
    • (1996) J Neurosci , vol.16 , pp. 2553-2562
    • Desagher, S.1    Glowinski, J.2    Premont, J.3
  • 16
    • 0029915162 scopus 로고    scopus 로고
    • Glia conditioned medium protects fetal rat midbrain neurons in culture from L-DOPA toxicity
    • Mena MA, Casarejos MJ, Carazo A, et al. Glia conditioned medium protects fetal rat midbrain neurons in culture from L-DOPA toxicity. Neuroreport 1996;7:441-445.
    • (1996) Neuroreport , vol.7 , pp. 441-445
    • Mena, M.A.1    Casarejos, M.J.2    Carazo, A.3
  • 17
    • 0037996661 scopus 로고    scopus 로고
    • Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress
    • Shih AY, Johnson DA, Wong G, et al. Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress. J Neurosci 2003;23:3394-3406.
    • (2003) J Neurosci , vol.23 , pp. 3394-3406
    • Shih, A.Y.1    Johnson, D.A.2    Wong, G.3
  • 18
    • 0027482761 scopus 로고
    • Human immunodeficiency virus type 1 infection of the brain
    • Atwood WJ, Berger JR, Kaderman R, et al. Human immunodeficiency virus type 1 infection of the brain. Clin Microbiol Rev 1993;6:339-366.
    • (1993) Clin Microbiol Rev , vol.6 , pp. 339-366
    • Atwood, W.J.1    Berger, J.R.2    Kaderman, R.3
  • 19
    • 0032989672 scopus 로고    scopus 로고
    • Astrocytes: HIV cellular reservoirs and important participants in neuropathogenesis
    • Brack-Werner R. Astrocytes: HIV cellular reservoirs and important participants in neuropathogenesis. Aids 1999;13:1-22.
    • (1999) Aids , vol.13 , pp. 1-22
    • Brack-Werner, R.1
  • 20
    • 0037417220 scopus 로고    scopus 로고
    • Apoptosis and caspases in neurodegenerative diseases
    • Friedlander RM. Apoptosis and caspases in neurodegenerative diseases. N Engl J Med 2003;348:1365-1375.
    • (2003) N Engl J Med , vol.348 , pp. 1365-1375
    • Friedlander, R.M.1
  • 21
    • 0038784588 scopus 로고    scopus 로고
    • Differential transcriptional regulation by human immunodeficiency virus type 1 and gp120 in human astrocytes
    • Galey D, Becker K, Haughey N, et al. Differential transcriptional regulation by human immunodeficiency virus type 1 and gp120 in human astrocytes. J Neurovirol 2003;9:358-371.
    • (2003) J Neurovirol , vol.9 , pp. 358-371
    • Galey, D.1    Becker, K.2    Haughey, N.3
  • 22
    • 3042847441 scopus 로고    scopus 로고
    • Possible involvement of both endoplasmic reticulum- and mitochondria-dependent pathways in MoMuLV-ts1-induced apoptosis in astrocytes
    • Liu N, Kuang X, Kim HT, et al. Possible involvement of both endoplasmic reticulum- and mitochondria-dependent pathways in MoMuLV-ts1-induced apoptosis in astrocytes. J Neurovirol 2004;10:189-198.
    • (2004) J Neurovirol , vol.10 , pp. 189-198
    • Liu, N.1    Kuang, X.2    Kim, H.T.3
  • 24
    • 12444328663 scopus 로고    scopus 로고
    • Control of Atm-/-thymic lymphoma cell proliferation in vitro and in vivo by dexamethasone
    • Kuang X, Yan M, Liu N, et al. Control of Atm-/-thymic lymphoma cell proliferation in vitro and in vivo by dexamethasone. Cancer Chemother Pharmacol 2005;55:203-212.
    • (2005) Cancer Chemother Pharmacol , vol.55 , pp. 203-212
    • Kuang, X.1    Yan, M.2    Liu, N.3
  • 25
    • 0037105720 scopus 로고    scopus 로고
    • Prevention of thymic lymphoma development in Atm-/- mice by dexamethasone
    • Yan M, Kuang X, Qiang W, et al. Prevention of thymic lymphoma development in Atm-/- mice by dexamethasone. Cancer Res 2002;62:5153-5157.
    • (2002) Cancer Res , vol.62 , pp. 5153-5157
    • Yan, M.1    Kuang, X.2    Qiang, W.3
  • 26
    • 0035019463 scopus 로고    scopus 로고
    • The ataxia-telangiectasia gene product may modulate DNA turnover and control cell fate by regulating cellular redox in lymphocytes
    • Yan M, Qiang W, Liu N, et al. The ataxia-telangiectasia gene product may modulate DNA turnover and control cell fate by regulating cellular redox in lymphocytes. FASEB J 2001;15:1132-1138.
    • (2001) FASEB J , vol.15 , pp. 1132-1138
    • Yan, M.1    Qiang, W.2    Liu, N.3
  • 27
    • 0029117261 scopus 로고
    • Neuroimmunodegeneration: Do neurons and T cells use common pathways for cell death?
    • Lynn WS, Wong PKY. Neuroimmunodegeneration: do neurons and T cells use common pathways for cell death? FASEB J 1995;9:1147-1156.
    • (1995) FASEB J , vol.9 , pp. 1147-1156
    • Lynn, W.S.1    Wong, P.K.Y.2
  • 28
    • 0027408211 scopus 로고
    • Correlation of specific virus-astrocyte interactions and cytopathic effects induced by ts1, a neurovirulent mutant of Moloney murine leukemia virus
    • Shikova E, Lin YC, Saha K, et al. Correlation of specific virus-astrocyte interactions and cytopathic effects induced by ts1, a neurovirulent mutant of Moloney murine leukemia virus. J Virol 1993;67:1137-1147.
    • (1993) J Virol , vol.67 , pp. 1137-1147
    • Shikova, E.1    Lin, Y.C.2    Saha, K.3
  • 29
    • 0036692295 scopus 로고    scopus 로고
    • The peroxisome proliferator phenylbutyric acid (PBA) protects astrocytes from ts1 MoMuLV-induced oxidative cell death
    • Liu N, Qiang W, Kuang X, et al. The peroxisome proliferator phenylbutyric acid (PBA) protects astrocytes from ts1 MoMuLV-induced oxidative cell death. J Neurovirol 2002;8:318-325.
    • (2002) J Neurovirol , vol.8 , pp. 318-325
    • Liu, N.1    Qiang, W.2    Kuang, X.3
  • 30
    • 10644264422 scopus 로고    scopus 로고
    • Abundant expression of zinc transporters in Bergman glia of mouse cerebellum
    • Wang ZY, Stoltenberg M, Huang L, et al. Abundant expression of zinc transporters in Bergman glia of mouse cerebellum. Brain Res Bull 2005;64:441-448.
    • (2005) Brain Res Bull , vol.64 , pp. 441-448
    • Wang, Z.Y.1    Stoltenberg, M.2    Huang, L.3
  • 31
    • 0032697807 scopus 로고    scopus 로고
    • Ataxia telangiectasia mutated deficiency affects astrocyte growth but not radiosensitivity
    • Gosink EC, Chong MJ, McKinnon PJ. Ataxia telangiectasia mutated deficiency affects astrocyte growth but not radiosensitivity. Cancer Res 1999;59:5294-5298.
    • (1999) Cancer Res , vol.59 , pp. 5294-5298
    • Gosink, E.C.1    Chong, M.J.2    McKinnon, P.J.3
  • 32
    • 13144251195 scopus 로고    scopus 로고
    • Possible control of cell death pathways in ataxia telangiectasia. A case report
    • Lynn WS, Wong PKY. Possible control of cell death pathways in ataxia telangiectasia. A case report. Neuroimmunomodulation 1997;4:277-284.
    • (1997) Neuroimmunomodulation , vol.4 , pp. 277-284
    • Lynn, W.S.1    Wong, P.K.Y.2
  • 33
    • 12944301005 scopus 로고    scopus 로고
    • L-serine and glycine serve as major astroglia-derived trophic factors for cerebellar Purkinje neurons
    • USA
    • Furuya S, Tabata T, Mitoma J, et al. L-serine and glycine serve as major astroglia-derived trophic factors for cerebellar Purkinje neurons. Proc Natl Acad Sci USA 2000;97:11528-11533.
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 11528-11533
    • Furuya, S.1    Tabata, T.2    Mitoma, J.3
  • 34
    • 0038636003 scopus 로고    scopus 로고
    • Glutathione pathways in the brain
    • Dringen R, Hirrlinger J. Glutathione pathways in the brain. Biol Chem 2003;384:505-516.
    • (2003) Biol Chem , vol.384 , pp. 505-516
    • Dringen, R.1    Hirrlinger, J.2
  • 35
    • 0001412747 scopus 로고    scopus 로고
    • Astrocytes provide cysteine to neurons by releasing glutathione
    • Wang XF, Cynader MS. Astrocytes provide cysteine to neurons by releasing glutathione. J Neurochem 2000;74:1434-1442.
    • (2000) J Neurochem , vol.74 , pp. 1434-1442
    • Wang, X.F.1    Cynader, M.S.2
  • 36
    • 0035873398 scopus 로고    scopus 로고
    • Pyruvate released by astrocytes protects neurons from copper-catalyzed cysteine neurotoxicity
    • Wang XF, Cynader MS. Pyruvate released by astrocytes protects neurons from copper-catalyzed cysteine neurotoxicity. J Neurosci 2001;21:3322-3331.
    • (2001) J Neurosci , vol.21 , pp. 3322-3331
    • Wang, X.F.1    Cynader, M.S.2
  • 37
    • 0042661173 scopus 로고    scopus 로고
    • The effect of oxidative stress on accumulation of apolipoprotein E3 and E4 in a cell culture model of beta-amyloid angiopathy (CAA)
    • Mazur-Kolecka B, Kowal D, Sukontasup T, et al. The effect of oxidative stress on accumulation of apolipoprotein E3 and E4 in a cell culture model of beta-amyloid angiopathy (CAA). Brain Res 2003;983:48-57.
    • (2003) Brain Res , vol.983 , pp. 48-57
    • Mazur-Kolecka, B.1    Kowal, D.2    Sukontasup, T.3
  • 38
    • 6344291668 scopus 로고    scopus 로고
    • Activation of transcription factor Nrf-2 and its downstream targets in response to moloney murine leukemia virus ts1-induced thiol depletion and oxidative stress in astrocytes
    • Qiang W, Cahill JM, Liu J, et al. Activation of transcription factor Nrf-2 and its downstream targets in response to moloney murine leukemia virus ts1-induced thiol depletion and oxidative stress in astrocytes. J Virol 2004;78:11926-11938.
    • (2004) J Virol , vol.78 , pp. 11926-11938
    • Qiang, W.1    Cahill, J.M.2    Liu, J.3
  • 39
    • 9444267679 scopus 로고    scopus 로고
    • Reoxygenation after severe hypoxia induces cardiomyocyte hypertrophy in vitro: Activation of CREB downstream of GSK3beta
    • El Jamali A, Freund C, Rechner C, et al. Reoxygenation after severe hypoxia induces cardiomyocyte hypertrophy in vitro: activation of CREB downstream of GSK3beta. FASEB J 2004;18:1096-1098.
    • (2004) FASEB J , vol.18 , pp. 1096-1098
    • El Jamali, A.1    Freund, C.2    Rechner, C.3
  • 40
    • 3543084994 scopus 로고    scopus 로고
    • Distinct roles of c-Abl and Atm in oxidative stress response are mediated by protein kinase C delta
    • Li B, Wang X, Rasheed N, et al. Distinct roles of c-Abl and Atm in oxidative stress response are mediated by protein kinase C delta. Genes Dev 2004;18:1824-1837.
    • (2004) Genes Dev , vol.18 , pp. 1824-1837
    • Li, B.1    Wang, X.2    Rasheed, N.3
  • 41
    • 2942608911 scopus 로고    scopus 로고
    • Aldosterone potentiates angiotensin II-induced signaling in vascular smooth muscle cells
    • Mazak I, Fiebeler A, Muller DN, et al. Aldosterone potentiates angiotensin II-induced signaling in vascular smooth muscle cells. Circulation 2004;109:2792-2800.
    • (2004) Circulation , vol.109 , pp. 2792-2800
    • Mazak, I.1    Fiebeler, A.2    Muller, D.N.3
  • 42
    • 15844426692 scopus 로고    scopus 로고
    • Atm-deficient mice: A paradigm of ataxia telangiectasia
    • Barlow C, Hirotsune S, Paylor R, et al. Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell 1996;86:159-171.
    • (1996) Cell , vol.86 , pp. 159-171
    • Barlow, C.1    Hirotsune, S.2    Paylor, R.3
  • 43
    • 0029848286 scopus 로고    scopus 로고
    • Pleiotropic defects in ataxia-telangiectasia protein-deficient mice
    • USA
    • Elson A, Wang Y, Daugherty CJ, et al. Pleiotropic defects in ataxia-telangiectasia protein-deficient mice. Proc Natl Acad Sci USA 1996;93:13084-13089.
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 13084-13089
    • Elson, A.1    Wang, Y.2    Daugherty, C.J.3
  • 44
    • 0030933152 scopus 로고    scopus 로고
    • The genetic defect in ataxia-telangiectasia
    • Lavin MF, Shiloh Y. The genetic defect in ataxia-telangiectasia. Annu Rev Immunol 1997;15:177-202.
    • (1997) Annu Rev Immunol , vol.15 , pp. 177-202
    • Lavin, M.F.1    Shiloh, Y.2
  • 45
    • 0029821651 scopus 로고    scopus 로고
    • Dual roles of ATM in the cellular response to radiation and in cell growth control
    • Xu Y, Baltimore D. Dual roles of ATM in the cellular response to radiation and in cell growth control. Genes Dev 1996;10:2401-2410.
    • (1996) Genes Dev , vol.10 , pp. 2401-2410
    • Xu, Y.1    Baltimore, D.2
  • 46
    • 4444246996 scopus 로고    scopus 로고
    • Reactive oxygen species induced by the deletion of peroxiredoxin II(PrxII) increases the number of thymocytes resulting in the enlargement of PrxII-null thymus
    • Moon EY, Han YH, Lee DS, et al. Reactive oxygen species induced by the deletion of peroxiredoxin II(PrxII) increases the number of thymocytes resulting in the enlargement of PrxII-null thymus. Eur J Immunol 2004;34:2119-2128.
    • (2004) Eur J Immunol , vol.34 , pp. 2119-2128
    • Moon, E.Y.1    Han, Y.H.2    Lee, D.S.3
  • 47
    • 8644273225 scopus 로고    scopus 로고
    • Cell-density-dependent regulation of neural precursor cell function
    • USA
    • Limoli CL, Rola R, Giedzinski E, et al. Cell-density-dependent regulation of neural precursor cell function. Proc Natl Acad Sci USA 2004;101:16052-16057.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 16052-16057
    • Limoli, C.L.1    Rola, R.2    Giedzinski, E.3
  • 48
    • 0034873185 scopus 로고    scopus 로고
    • Reactive oxygen species as intracellular messengers during cell growth and differentiation
    • Sauer H, Wartenberg M, Hescheler J. Reactive oxygen species as intracellular messengers during cell growth and differentiation. Cell Physiol Biochem 2001;11:173-186.
    • (2001) Cell Physiol Biochem , vol.11 , pp. 173-186
    • Sauer, H.1    Wartenberg, M.2    Hescheler, J.3
  • 49
    • 0023160233 scopus 로고
    • Impaired glutathione biosynthesis in cultured human ataxia-telangiectasia cells
    • Meredith MJ, Dodson ML. Impaired glutathione biosynthesis in cultured human ataxia-telangiectasia cells. Cancer Res 1987;47:4576-4581.
    • (1987) Cancer Res , vol.47 , pp. 4576-4581
    • Meredith, M.J.1    Dodson, M.L.2
  • 50
    • 3442902484 scopus 로고    scopus 로고
    • Effect of N-acetyl cysteine on oxidative DNA damage and the frequency of DNA deletions in atm-deficient mice
    • Reliene R, Fischer E, Schiestl RH. Effect of N-acetyl cysteine on oxidative DNA damage and the frequency of DNA deletions in atm-deficient mice. Cancer Res 2004;64:5148-5153.
    • (2004) Cancer Res , vol.64 , pp. 5148-5153
    • Reliene, R.1    Fischer, E.2    Schiestl, R.H.3
  • 51
    • 19244365393 scopus 로고    scopus 로고
    • Stress, protein (mis)folding, and signaling: The redox connection
    • Sitia R, Molteni SN. Stress, protein (mis)folding, and signaling: the redox connection. Sci STKE 2004;239:pe27.
    • (2004) Sci STKE , vol.239
    • Sitia, R.1    Molteni, S.N.2
  • 52
    • 0033562966 scopus 로고    scopus 로고
    • Stress signaling from the lumen of the endoplasmic reticulum: Coordination of gene transcriptional and translational controls
    • Kaufman RJ. Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev 1999;13:1211-1233.
    • (1999) Genes Dev , vol.13 , pp. 1211-1233
    • Kaufman, R.J.1
  • 53
    • 0035966320 scopus 로고    scopus 로고
    • The unfolding tale of the unfolded protein response
    • Ma Y, Hendershot LM. The unfolding tale of the unfolded protein response. Cell 2001;107:827-830.
    • (2001) Cell , vol.107 , pp. 827-830
    • Ma, Y.1    Hendershot, L.M.2
  • 54
    • 0035212589 scopus 로고    scopus 로고
    • The ups and downs of MEK kinase interactions
    • Hagemann C, Blank JL. The ups and downs of MEK kinase interactions. Cell Signal 2001;13:863-875.
    • (2001) Cell Signal , vol.13 , pp. 863-875
    • Hagemann, C.1    Blank, J.L.2
  • 55
    • 0030049439 scopus 로고    scopus 로고
    • 2. Role in cell survival following oxidant injury
    • 2. Role in cell survival following oxidant injury. J Biol Chem 1996;271:4138-4142.
    • (1996) J Biol Chem , vol.271 , pp. 4138-4142
    • Guyton, K.Z.1    Liu, Y.2    Gorospe, M.3
  • 56
    • 0003029344 scopus 로고    scopus 로고
    • ts1 MoMuLV: A murine model of neuroimmunodegeneration
    • Wong PKY, Lynn WS (eds). R.G. Landes: Heidelberg
    • Wong PKY, Lynn WS, Lin YC, et al. ts1 MoMuLV: a murine model of neuroimmunodegeneration. In: Wong PKY, Lynn WS (eds). Neuroimmunodegeneration. R.G. Landes: Heidelberg, 1998, pp 75-93.
    • (1998) Neuroimmunodegeneration , pp. 75-93
    • Wong, P.K.Y.1    Lynn, W.S.2    Lin, Y.C.3
  • 57
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Xia Z, Dickens M, Raingeaud J, et al. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995;270:1326-1331.
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3
  • 58
    • 0032921811 scopus 로고    scopus 로고
    • Hydrogen peroxide activation of multiple mitogen-activated protein kinases in an oligodendrocyte cell line: Role of extracellular signal-regulated kinase in hydrogen peroxide-induced cell death
    • Bhat NR, Zhang P. Hydrogen peroxide activation of multiple mitogen-activated protein kinases in an oligodendrocyte cell line: role of extracellular signal-regulated kinase in hydrogen peroxide-induced cell death. J Neurochem 1999;72:112-119.
    • (1999) J Neurochem , vol.72 , pp. 112-119
    • Bhat, N.R.1    Zhang, P.2
  • 59
    • 0036325892 scopus 로고    scopus 로고
    • Immature and mature cortical neurons engage different apoptotic mechanisms involving caspase-3 and the mitogen-activated protein kinase pathway
    • Lesuisse C, Martin LJ. Immature and mature cortical neurons engage different apoptotic mechanisms involving caspase-3 and the mitogen-activated protein kinase pathway. J Cereb Blood Flow Metab 2002;22:935-950.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 935-950
    • Lesuisse, C.1    Martin, L.J.2
  • 60
    • 0037107185 scopus 로고    scopus 로고
    • Copper/zinc superoxide dismutase attenuates neuronal cell death by preventing extracellular signal-regulated kinase activation after transient focal cerebral ischemia in mice
    • Noshita N, Sugawara T, Hayashi T, et al. Copper/zinc superoxide dismutase attenuates neuronal cell death by preventing extracellular signal-regulated kinase activation after transient focal cerebral ischemia in mice. J Neurosci 2002;22:7923-7930.
    • (2002) J Neurosci , vol.22 , pp. 7923-7930
    • Noshita, N.1    Sugawara, T.2    Hayashi, T.3
  • 61
    • 0034697364 scopus 로고    scopus 로고
    • Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and primary cortical neuron cultures
    • Stanciu M, Wang Y, Kentor R, et al. Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and primary cortical neuron cultures. J Biol Chem 2000;275:12200-12206.
    • (2000) J Biol Chem , vol.275 , pp. 12200-12206
    • Stanciu, M.1    Wang, Y.2    Kentor, R.3
  • 62
    • 2442608520 scopus 로고    scopus 로고
    • ERK activation promotes neuronal degeneration predominantly through plasma membrane damage and independently of caspase-3
    • Subramaniam S, Zirrgiebel U, von Bohlen Und Halbach O, et al. ERK activation promotes neuronal degeneration predominantly through plasma membrane damage and independently of caspase-3. J Cell Biol 2004;165:357-369.
    • (2004) J Cell Biol , vol.165 , pp. 357-369
    • Subramaniam, S.1    Zirrgiebel, U.2    Von Bohlen Und Halbach, O.3
  • 63
    • 2942517676 scopus 로고    scopus 로고
    • Oxidative neuronal injury: The dark side of ERK1/2
    • Chu CT, Levinthal DJ, Kulich SM, et al. Oxidative neuronal injury: the dark side of ERK1/2. Eur J Biochem 2004;271:2060-2066.
    • (2004) Eur J Biochem , vol.271 , pp. 2060-2066
    • Chu, C.T.1    Levinthal, D.J.2    Kulich, S.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.