메뉴 건너뛰기




Volumn 53, Issue 10, 2010, Pages 778-786

Molecular genetic characterization of Drosophila ATM conserved functional domains

Author keywords

Ataxia telangiectasia mutated; FATC domain; HEAT repeat; Telomere

Indexed keywords

ATM PROTEIN; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; PROTEIN SERINE THREONINE KINASE; TUMOR SUPPRESSOR PROTEIN;

EID: 78650105973     PISSN: 08312796     EISSN: None     Source Type: Journal    
DOI: 10.1139/G10-067     Document Type: Article
Times cited : (10)

References (48)
  • 1
    • 0033049578 scopus 로고    scopus 로고
    • Telomere loss in somatic cells of Drosophila causes cell cycle arrest and apoptosis
    • PMID:10049921.
    • Ahmad, K., and Golic, K.G. 1999. Telomere loss in somatic cells of Drosophila causes cell cycle arrest and apoptosis. Genetics, 151(3): 1041-1051. PMID:10049921.
    • (1999) Genetics , vol.151 , Issue.3 , pp. 1041-1051
    • Ahmad, K.1    Golic, K.G.2
  • 2
    • 0029392854 scopus 로고
    • HEAT repeats in the Huntington's disease protein
    • doi:10.1038/ ng1095-115. PMID:7550332.
    • Andrade, M.A., and Bork, P. 1995. HEAT repeats in the Huntington's disease protein. Nat. Genet. 11(2): 115-116. doi:10.1038/ ng1095-115. PMID:7550332.
    • (1995) Nat. Genet. , vol.11 , Issue.2 , pp. 115-116
    • Andrade, M.A.1    Bork, P.2
  • 3
    • 4143075951 scopus 로고    scopus 로고
    • Telomere protection without a telomerase: The role of ATM and Mre11 in Drosophila telomere maintenance
    • doi:10.1016/ j.cub.2004.06.063. PMID: 15296751.
    • Bi, X., Wei, S.C., and Rong, Y.S. 2004. Telomere protection without a telomerase: the role of ATM and Mre11 in Drosophila telomere maintenance. Curr. Biol. 14(15): 1348-1353. doi:10.1016/ j.cub.2004.06.063. PMID: 15296751.
    • (2004) Curr. Biol. , vol.14 , Issue.15 , pp. 1348-1353
    • Bi, X.1    Wei, S.C.2    Rong, Y.S.3
  • 4
    • 31544437686 scopus 로고    scopus 로고
    • 2/M checkpoint induced by low-dose irradiation
    • doi: 10.1534/ genetics. 105.047720. PMID: 16020777.
    • 2/M checkpoint induced by low-dose irradiation. Genetics, 171(2): 845-847. doi: 10.1534/ genetics. 105.047720. PMID: 16020777.
    • (2005) Genetics , vol.171 , Issue.2 , pp. 845-847
    • Bi, X.1    Gong, M.2    Srikanta, D.3    Rong, Y.4
  • 5
    • 27244436111 scopus 로고    scopus 로고
    • Drosophila ATM and ATR checkpoint kinases control partially redundant pathways for telomere maintenance
    • doi:10.1073/pnas.0504981102. PMID:16203987.
    • Bi, X., Srikanta, D., Fanti, L., Pimpinelli, S., Badugu, R., Kellum, R., and Rong, Y.S. 2005b. Drosophila ATM and ATR checkpoint kinases control partially redundant pathways for telomere maintenance. Proc. Natl. Acad. Sci. U.S.A. 102(42): 15167-15172. doi:10.1073/pnas.0504981102. PMID:16203987.
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , Issue.42 , pp. 15167-15172
    • Bi, X.1    Srikanta, D.2    Fanti, L.3    Pimpinelli, S.4    Badugu, R.5    Kellum, R.6    Rong, Y.S.7
  • 6
    • 0034193150 scopus 로고    scopus 로고
    • FAT: A novel domain in PIK-related kinases
    • doi:10.1016/S0968-0004(00)01563-2. PMID: 10782091.
    • Bosotti, R., Isacchi, A., and Sonnhammer, E.L. 2000. FAT: a novel domain in PIK-related kinases. Trends Biochem. Sci. 25(5): 225-227. doi:10.1016/S0968-0004(00)01563-2. PMID: 10782091.
    • (2000) Trends Biochem. Sci. , vol.25 , Issue.5 , pp. 225-227
    • Bosotti, R.1    Isacchi, A.2    Sonnhammer, E.L.3
  • 7
    • 1642540218 scopus 로고    scopus 로고
    • Drosophila melanogaster MNK/ Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage
    • doi:10.1128/MCB.24.3.1219-1231.2004. PMID:14729967.
    • Brodsky, M.H., Weinert, B.T., Tsang, G., Rong, Y.S., McGinnis, N.M., Golic, K.G., et al. 2004. Drosophila melanogaster MNK/ Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage. Mol. Cell. Biol. 24(3): 1219-1231. doi:10.1128/MCB.24.3.1219-1231.2004. PMID:14729967.
    • (2004) Mol. Cell. Biol. , vol.24 , Issue.3 , pp. 1219-1231
    • Brodsky, M.H.1    Weinert, B.T.2    Tsang, G.3    Rong, Y.S.4    McGinnis, N.M.5    Golic, K.G.6
  • 8
    • 25144468434 scopus 로고    scopus 로고
    • The mechanism of telomere protection: A comparison between Drosophila and humans
    • doi:10.1007/s00412-005-0005-9. PMID: 16012858.
    • Cenci, G., Ciapponi, L., and Gatti, M. 2005. The mechanism of telomere protection: a comparison between Drosophila and humans. Chromosoma, 114(3): 135-145. doi:10.1007/s00412-005-0005-9. PMID: 16012858.
    • (2005) Chromosoma , vol.114 , Issue.3 , pp. 135-145
    • Cenci, G.1    Ciapponi, L.2    Gatti, M.3
  • 9
    • 59649089118 scopus 로고    scopus 로고
    • Telomere capping and cellular checkpoints: Clues from fruit flies
    • doi:10.1159/000167824. PMID:19188707.
    • Ciapponi, L., and Cenci, G. 2008. Telomere capping and cellular checkpoints: clues from fruit flies. Cytogenet. Genome Res. 122(3-4): 365-373. doi:10.1159/000167824. PMID:19188707.
    • (2008) Cytogenet. Genome Res. , vol.122 , Issue.3-4 , pp. 365-373
    • Ciapponi, L.1    Cenci, G.2
  • 10
    • 33746429164 scopus 로고    scopus 로고
    • The Drosophila Nbs protein functions in multiple pathways for the maintenance of genome stability
    • doi: 10.1534/ genetics.106.058081.PMID:16648644.
    • Ciapponi, L., Cenci, G., and Gatti, M. 2006. The Drosophila Nbs protein functions in multiple pathways for the maintenance of genome stability. Genetics, 173(3): 1447-1454. doi: 10.1534/ genetics.106.058081.PMID:16648644.
    • (2006) Genetics , vol.173 , Issue.3 , pp. 1447-1454
    • Ciapponi, L.1    Cenci, G.2    Gatti, M.3
  • 11
    • 17644362355 scopus 로고    scopus 로고
    • DNA damage-induced association of ATM with its target proteins requires a protein interaction domain in the N terminus of ATM
    • doi:10.1074/jbc.M412065200. PMID: 15713674.
    • Fernandes, N., Sun, Y., Chen, S., Paul, P., Shaw, R.J., Cantley, L.C., and Price, B.D. 2005. DNA damage-induced association of ATM with its target proteins requires a protein interaction domain in the N terminus of ATM. J. Biol. Chem. 280(15): 15158-15164. doi:10.1074/jbc.M412065200. PMID: 15713674.
    • (2005) J. Biol. Chem. , vol.280 , Issue.15 , pp. 15158-15164
    • Fernandes, N.1    Sun, Y.2    Chen, S.3    Paul, P.4    Shaw, R.J.5    Cantley, L.C.6    Price, B.D.7
  • 12
    • 40549111934 scopus 로고    scopus 로고
    • Protective mechanisms of p53-p21pRb proteins against DNA damage-induced cell death
    • PMID:18235223.
    • Garner, E., and Raj, K. 2008. Protective mechanisms of p53-p21pRb proteins against DNA damage-induced cell death. Cell Cycle, 7(3): 277-282. PMID:18235223.
    • (2008) Cell Cycle , vol.7 , Issue.3 , pp. 277-282
    • Garner, E.1    Raj, K.2
  • 13
    • 33644753146 scopus 로고    scopus 로고
    • Nipped-A, the Tral/TRRAP subunit of the Drosophila SAGA and Tip60 complexes, has multiple roles in Notch signaling during wing development
    • doi: 10.1128/MCB .26.6.2347-2359.2006. PMID:16508010.
    • Gause, M., Eissenberg, J.C, Macrae, A.F., Dorsett, M., Misulovin, Z., and Dorsett, D. 2006. Nipped-A, the Tral/TRRAP subunit of the Drosophila SAGA and Tip60 complexes, has multiple roles in Notch signaling during wing development. Mol. Cell. Biol. 26(6): 2347-2359. doi: 10.1128/MCB .26.6.2347-2359.2006. PMID:16508010.
    • (2006) Mol. Cell. Biol. , vol.26 , Issue.6 , pp. 2347-2359
    • Gause, M.1    Eissenberg, J.C.2    Macrae, A.F.3    Dorsett, M.4    Misulovin, Z.5    Dorsett, D.6
  • 14
    • 33646201928 scopus 로고    scopus 로고
    • Mutations in the extra sex combs and Enhancer of Polycomb genes increase homologous recombination in somatic cells of Drosophila melanogaster
    • doi:10.1534/ genetics. 105.042473. PMID: 16452150.
    • Holmes, A.M., Weedmark, K.A., and Gloor, G.B. 2006. Mutations in the extra sex combs and Enhancer of Polycomb genes increase homologous recombination in somatic cells of Drosophila melanogaster. Genetics, 172(4): 2367-2377. doi:10.1534/ genetics. 105.042473. PMID: 16452150.
    • (2006) Genetics , vol.172 , Issue.4 , pp. 2367-2377
    • Holmes, A.M.1    Weedmark, K.A.2    Gloor, G.B.3
  • 15
    • 33744942683 scopus 로고    scopus 로고
    • The FATC domains of PIKK proteins are functionally equivalent and participate in the Tip60-dependent activation of DNA-PKcs and ATM
    • doi:10.1074/ jbc.M513172200. PMID: 16603769.
    • Jiang, X., Sun, Y., Chen, S., Roy, K., and Price, B.D. 2006. The FATC domains of PIKK proteins are functionally equivalent and participate in the Tip60-dependent activation of DNA-PKcs and ATM. J. Biol. Chem. 281(23): 15741-15746. doi:10.1074/ jbc.M513172200. PMID: 16603769.
    • (2006) J. Biol. Chem. , vol.281 , Issue.23 , pp. 15741-15746
    • Jiang, X.1    Sun, Y.2    Chen, S.3    Roy, K.4    Price, B.D.5
  • 16
    • 69249240178 scopus 로고    scopus 로고
    • The combined status of ATM and p53 link tumor development with therapeutic response
    • doi:10.1101/gad.1815309. PMID: 19608766.
    • Jiang, H., Reinhardt, H.C, Bartkova, J., Tommiska, J., Blomqvist, C., Nevanlinna, H., et al. 2009. The combined status of ATM and p53 link tumor development with therapeutic response. Genes Dev. 23(16): 1895-1909. doi:10.1101/gad.1815309. PMID: 19608766.
    • (2009) Genes Dev. , vol.23 , Issue.16 , pp. 1895-1909
    • Jiang, H.1    Reinhardt, H.C.2    Bartkova, J.3    Tommiska, J.4    Blomqvist, C.5    Nevanlinna, H.6
  • 17
    • 38849135851 scopus 로고    scopus 로고
    • DNA double-strand break repair defects in syndromes associated with acute radiation response: At least two different assays to predict intrinsic radiosensitivity?
    • doi:10.1080/ 09553000701797039. PMID: 18246480.
    • Joubert, A., Zimmerman, K.M., Bencokova, Z., Gastaldo, J., Chavaudra, N., Favaudon, V., et al. 2008. DNA double-strand break repair defects in syndromes associated with acute radiation response: at least two different assays to predict intrinsic radiosensitivity? Int. J. Radiat. Biol. 84(2): 107-125. doi:10.1080/ 09553000701797039. PMID: 18246480.
    • (2008) Int. J. Radiat. Biol. , vol.84 , Issue.2 , pp. 107-125
    • Joubert, A.1    Zimmerman, K.M.2    Bencokova, Z.3    Gastaldo, J.4    Chavaudra, N.5    Favaudon, V.6
  • 18
    • 33845468254 scopus 로고    scopus 로고
    • ATM and ATR pathways signal alternative splicing of Drosophila TAF1 pre-mRNA in response to DNA damage
    • doi:10.1128/MCB.01125-06. PMID: 17030624.
    • Katzenberger, R.J., Marengo, M.S., and Wassarman, D.A. 2006. ATM and ATR pathways signal alternative splicing of Drosophila TAF1 pre-mRNA in response to DNA damage. Mol. Cell. Biol. 26(24): 9256-9267. doi:10.1128/MCB.01125-06. PMID: 17030624.
    • (2006) Mol. Cell. Biol. , vol.26 , Issue.24 , pp. 9256-9267
    • Katzenberger, R.J.1    Marengo, M.S.2    Wassarman, D.A.3
  • 19
    • 36949013395 scopus 로고    scopus 로고
    • ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks
    • doi:10.1038/sj.onc.1210880. PMID:18066087.
    • Lavin, M.F. 2007. ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks. Oncogene, 26(56): 7749-7758. doi:10.1038/sj.onc.1210880. PMID:18066087.
    • (2007) Oncogene , vol.26 , Issue.56 , pp. 7749-7758
    • Lavin, M.F.1
  • 20
    • 52449114574 scopus 로고    scopus 로고
    • Ataxia-telangiectasia: From a rare disorder to a paradigm for cell signalling and cancer
    • doi:10.1038/nrm2514. PMID: 18813293.
    • Lavin, M.F. 2008. Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer. Nat. Rev. Mol. Cell Biol. 9(10): 759-769. doi:10.1038/nrm2514. PMID: 18813293.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , Issue.10 , pp. 759-769
    • Lavin, M.F.1
  • 21
    • 70350324640 scopus 로고    scopus 로고
    • Emerging common themes in regulation of PIKKs and PI3Ks
    • doi:10.1038/emboj.2009.281. PMID: 19779456.
    • Lempiäinen, H., and Halazonetis, T.D. 2009. Emerging common themes in regulation of PIKKs and PI3Ks. EMBO J. 28(20): 3067-3073. doi:10.1038/emboj.2009.281. PMID: 19779456.
    • (2009) EMBO J. , vol.28 , Issue.20 , pp. 3067-3073
    • Lempiäinen, H.1    Halazonetis, T.D.2
  • 22
    • 4544281398 scopus 로고    scopus 로고
    • Choreography of the DNA damage response: Spatiotemporal relationships among checkpoint and repair proteins
    • doi:10.1016/j.cell.2004.08.015. PMID: 15369670.
    • Lisby, M., Barlow, J.H., Burgess, R.C., and Rothstein, R. 2004. Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins. Cell, 118(6): 699-713. doi:10.1016/j.cell.2004. 08.015. PMID: 15369670.
    • (2004) Cell , vol.118 , Issue.6 , pp. 699-713
    • Lisby, M.1    Barlow, J.H.2    Burgess, R.C.3    Rothstein, R.4
  • 23
    • 34247260964 scopus 로고    scopus 로고
    • Distant N- And C-terminal domains are required for intrinsic kinase activity of SMG-1, a critical component of nonsense-mediated mRNA decay
    • doi:10.1074/jbc.M610159200. PMID: 17229728.
    • Morita, T., Yamashita, A., Kashima, I., Ogata, K., Ishiura, S., and Ohno, S. 2007. Distant N- and C-terminal domains are required for intrinsic kinase activity of SMG-1, a critical component of nonsense-mediated mRNA decay. J. Biol. Chem. 282(11): 7799-7808. doi:10.1074/jbc.M610159200. PMID: 17229728.
    • (2007) J. Biol. Chem. , vol.282 , Issue.11 , pp. 7799-7808
    • Morita, T.1    Yamashita, A.2    Kashima, I.3    Ogata, K.4    Ishiura, S.5    Ohno, S.6
  • 24
    • 27644482826 scopus 로고    scopus 로고
    • Role of the C terminus of Mec1 checkpoint kinase in its localization to sites of DNA damage
    • doi:10.1091/mbc.E05-05-0405. PMID: 16148046.
    • Nakada, D., Hirano, Y., Tanaka, Y., and Sugimoto, K. 2005. Role of the C terminus of Mec1 checkpoint kinase in its localization to sites of DNA damage. Mol. Biol. Cell, 16(11): 5227-5235. doi:10.1091/mbc.E05-05-0405. PMID: 16148046.
    • (2005) Mol. Biol. Cell , vol.16 , Issue.11 , pp. 5227-5235
    • Nakada, D.1    Hirano, Y.2    Tanaka, Y.3    Sugimoto, K.4
  • 25
    • 3543088493 scopus 로고    scopus 로고
    • Drosophila atm/telomere fusion is required for telomeric localization of HPl and telomere position effect
    • doi:10.1101/gad.1202504. PMID:15256487.
    • Oikemus, S.R., McGinnis, N., Queiroz-Machado, J., Tukachinsky, H., Takada, S., Sunkel, C.E., and Brodsky, M.H. 2004. Drosophila atm/telomere fusion is required for telomeric localization of HPl and telomere position effect. Genes Dev. 18(15): 1850-1861. doi:10.1101/gad.1202504. PMID:15256487.
    • (2004) Genes Dev , vol.18 , Issue.15 , pp. 1850-1861
    • Oikemus, S.R.1    McGinnis, N.2    Queiroz-Machado, J.3    Tukachinsky, H.4    Takada, S.5    Sunkel, C.E.6    Brodsky, M.H.7
  • 26
    • 33646946743 scopus 로고    scopus 로고
    • Epigenetic telomere protection by Drosophila DNA damage response pathways
    • doi:10.1371/journal.pgen.0020071. PMID:16710445.
    • Oikemus, S.R., Queiroz-Machado, J., Lai, K., McGinnis, N., Sunkel, C., and Brodsky, M.H. 2006. Epigenetic telomere protection by Drosophila DNA damage response pathways. PLoS Genet. 2(5): e71. doi:10.1371/journal.pgen.0020071. PMID:16710445.
    • (2006) PLoS Genet. , vol.2 , Issue.5
    • Oikemus, S.R.1    Queiroz-Machado, J.2    Lai, K.3    McGinnis, N.4    Sunkel, C.5    Brodsky, M.H.6
  • 27
    • 0346786214 scopus 로고    scopus 로고
    • Retrotransposons provide an evolutionarily robust non-telomerase mechanism to maintain telomeres
    • doi:10.1146/ annurev.genet.38.072902.093115. PMID:14616071.
    • Pardue, M.L., and DeBaryshe, P.G. 2003. Retrotransposons provide an evolutionarily robust non-telomerase mechanism to maintain telomeres. Annu. Rev. Genet. 37(1): 485-511. doi:10.1146/ annurev.genet.38.072902.093115. PMID:14616071.
    • (2003) Annu. Rev. Genet. , vol.37 , Issue.1 , pp. 485-511
    • Pardue, M.L.1    DeBaryshe, P.G.2
  • 28
    • 0037462453 scopus 로고    scopus 로고
    • The ATRs, ATMs, and TORs are giant HEAT repeat proteins
    • doi:10.1016/ S0092-8674(03)00033-3. PMID: 12553904.
    • Perry, J., and Kleckner, N. 2003. The ATRs, ATMs, and TORs are giant HEAT repeat proteins. Cell, 112(2): 151-155. doi:10.1016/ S0092-8674(03)00033-3. PMID: 12553904.
    • (2003) Cell , vol.112 , Issue.2 , pp. 151-155
    • Perry, J.1    Kleckner, N.2
  • 29
    • 33748897493 scopus 로고    scopus 로고
    • Drosophila Reptin and other TIP60 complex components promote generation of silent chromatin
    • doi:10.1534/ genetics.106.059980. PMID: 16816423.
    • Qi, D., Jin, H., Lilja, T., and Mannervik, M. 2006. Drosophila Reptin and other TIP60 complex components promote generation of silent chromatin. Genetics, 174(1): 241-251. doi:10.1534/ genetics.106.059980. PMID: 16816423.
    • (2006) Genetics , vol.174 , Issue.1 , pp. 241-251
    • Qi, D.1    Jin, H.2    Lilja, T.3    Mannervik, M.4
  • 30
    • 67651251435 scopus 로고    scopus 로고
    • Hyperactivation of DNA-PK by double-strand break mimicking molecules disorganizes DNA damage response
    • doi:10.1371/journal. pone.0006298. PMID: 19621083.
    • Quanz, M., Chassoux, D., Berthault, N., Agrario, C., Sun, J.S., Dutreix, M., and Fugmann, S.D. 2009. Hyperactivation of DNA-PK by double-strand break mimicking molecules disorganizes DNA damage response. PLoS One, 4(7): e6298. doi:10.1371/journal. pone.0006298. PMID: 19621083.
    • (2009) PLoS One , vol.4 , Issue.7
    • Quanz, M.1    Chassoux, D.2    Berthault, N.3    Agrario, C.4    Sun, J.S.5    Dutreix, M.6    Fugmann, S.D.7
  • 31
    • 0035036503 scopus 로고    scopus 로고
    • Tef: A mutation that causes telomere fusion and severe genome rearrangements in Drosophila melanogaster
    • doi:10.1007/ s004120000116. PMID:11398972.
    • Queiroz-Machado, J., Perdigão, J., Simões-Carvalho, P., Herrmann, S., and Sunkel, CE. 2001. tef: a mutation that causes telomere fusion and severe genome rearrangements in Drosophila melanogaster. Chromosoma, 110(1): 10-23. doi:10.1007/ s004120000116. PMID:11398972.
    • (2001) Chromosoma , vol.110 , Issue.1 , pp. 10-23
    • Queiroz-Machado, J.1    Perdigão, J.2    Simões-Carvalho, P.3    Herrmann, S.4    Sunkel, C.E.5
  • 32
    • 43249103898 scopus 로고    scopus 로고
    • Mutations in String/ CDC25 inhibit cell cycle re-entry and neurodegeneration in a Drosophila model of ataxia telangiectasia
    • doi:10.1101/gad.1639608. PMID: 18408079.
    • Rimkus, S.A., Katzenberger, R.J., Trinh, A.T., Dodson, G.E., Tibbetts, R.S., and Wassarman, D.A. 2008. Mutations in String/ CDC25 inhibit cell cycle re-entry and neurodegeneration in a Drosophila model of ataxia telangiectasia. Genes Dev. 22(9): 1205-1220. doi:10.1101/gad.1639608. PMID: 18408079.
    • (2008) Genes Dev. , vol.22 , Issue.9 , pp. 1205-1220
    • Rimkus, S.A.1    Katzenberger, R.J.2    Trinh, A.T.3    Dodson, G.E.4    Tibbetts, R.S.5    Wassarman, D.A.6
  • 33
    • 13844253934 scopus 로고    scopus 로고
    • Three-dimensional structure and regulation of the DNA-dependent protein kinase catalytic subunit (DNAPKcs)
    • doi:10.1016/j.str.2004.12.006. PMID:15698568.
    • Rivera-Calzada, A., Maman, J.P., Spagnolo, L., Pearl, L.H., and Llorca, O. 2005. Three-dimensional structure and regulation of the DNA-dependent protein kinase catalytic subunit (DNAPKcs). Structure, 13(2): 243-255. doi:10.1016/j.str.2004.12.006. PMID:15698568.
    • (2005) Structure , vol.13 , Issue.2 , pp. 243-255
    • Rivera-Calzada, A.1    Maman, J.P.2    Spagnolo, L.3    Pearl, L.H.4    Llorca, O.5
  • 34
    • 0037097866 scopus 로고    scopus 로고
    • Targeted mutagenesis by homologous recombination in D. melanogaster
    • doi:10.1101/gad.986602. PMID: 12080094.
    • Rong, Y.S., Titen, S.W., Xie, H.B., Golic, M.M., Bastiani, M., Bandyopadhyay, P., et al. 2002. Targeted mutagenesis by homologous recombination in D. melanogaster. Genes Dev. 16(12): 1568-1581. doi:10.1101/gad.986602. PMID: 12080094.
    • (2002) Genes Dev. , vol.16 , Issue.12 , pp. 1568-1581
    • Rong, Y.S.1    Titen, S.W.2    Xie, H.B.3    Golic, M.M.4    Bastiani, M.5    Bandyopadhyay, P.6
  • 35
    • 0035210210 scopus 로고    scopus 로고
    • ATM (ataxia telangiectasia mutated): Expanding roles in the DNA damage response and cellular homeostasis
    • doi:10.1042/ BST0290661. PMID: 11709050.
    • Shiloh, Y. 2001. ATM (ataxia telangiectasia mutated): expanding roles in the DNA damage response and cellular homeostasis. Biochem. Soc. Trans. 29(6): 661-666. doi:10.1042/ BST0290661. PMID: 11709050.
    • (2001) Biochem. Soc. Trans. , vol.29 , Issue.6 , pp. 661-666
    • Shiloh, Y.1
  • 36
    • 33745823159 scopus 로고    scopus 로고
    • The ATM-mediated DNA-damage response: Taking shape
    • doi:10.1016/j. tibs.2006.05.004. PMID:16774833.
    • Shiloh, Y. 2006. The ATM-mediated DNA-damage response: taking shape. Trends Biochem. Sci. 31(7): 402-410. doi:10.1016/j. tibs.2006.05.004. PMID:16774833.
    • (2006) Trends Biochem. Sci. , vol.31 , Issue.7 , pp. 402-410
    • Shiloh, Y.1
  • 37
    • 61649093808 scopus 로고    scopus 로고
    • Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks
    • doi:10.1016/j.molcel.2009.01.024. PMID: 19285939.
    • Shiotani, B., and Zou, L. 2009. Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks. Mol. Cell, 33(5): 547-558. doi:10.1016/j. molcel.2009.01.024. PMID: 19285939.
    • (2009) Mol. Cell , vol.33 , Issue.5 , pp. 547-558
    • Shiotani, B.1    Zou, L.2
  • 38
    • 4143123447 scopus 로고    scopus 로고
    • ATM is required for telomere maintenance and chromosome stability during Drosophila development
    • doi:10.1016/j.cub.2004.06.056. PMID: 15296750.
    • Silva, E., Tiong, S., Pedersen, M., Homola, E., Royou, A., Fasulo, B., et al. 2004. ATM is required for telomere maintenance and chromosome stability during Drosophila development. Curr. Biol. 14(15): 1341-1347. doi:10.1016/j.cub.2004.06.056. PMID: 15296750.
    • (2004) Curr. Biol. , vol.14 , Issue.15 , pp. 1341-1347
    • Silva, E.1    Tiong, S.2    Pedersen, M.3    Homola, E.4    Royou, A.5    Fasulo, B.6
  • 39
    • 0037447069 scopus 로고    scopus 로고
    • Drosophila p53 preserves genomic stability by regulating cell death
    • doi:10.1073/pnas. 0736384100. PMID: 12672954.
    • Sogame, N., Kim, M., and Abrams, J.M. 2003. Drosophila p53 preserves genomic stability by regulating cell death. Proc. Natl. Acad. Sci. U.S.A. 100(8): 4696-4701. doi:10.1073/pnas. 0736384100. PMID: 12672954.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , Issue.8 , pp. 4696-4701
    • Sogame, N.1    Kim, M.2    Abrams, J.M.3
  • 40
    • 4143134403 scopus 로고    scopus 로고
    • The Drosophila ATM ortholog, dATM, mediates the response to ionizing radiation and to spontaneous DNA damage during development
    • doi:10. 1016/j.cub.2004.06.064. PMID: 15296752.
    • Song, Y.H., Mirey, G., Betson, M., Haber, D.A., and Settleman, J. 2004. The Drosophila ATM ortholog, dATM, mediates the response to ionizing radiation and to spontaneous DNA damage during development. Curr. Biol. 14(15): 1354-1359. doi:10. 1016/j.cub.2004.06.064. PMID: 15296752.
    • (2004) Curr. Biol. , vol.14 , Issue.15 , pp. 1354-1359
    • Song, Y.H.1    Mirey, G.2    Betson, M.3    Haber, D.A.4    Settleman, J.5
  • 41
    • 24944516931 scopus 로고    scopus 로고
    • A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM
    • doi:10.1073/pnas.0504211102. PMID: 16141325.
    • Sun, Y., Jiang, X., Chen, S., Fernandes, N., and Price, B.D. 2005. A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM. Proc. Natl. Acad. Sci. U.S.A. 102(37): 13182-13187. doi:10.1073/pnas. 0504211102. PMID: 16141325.
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , Issue.37 , pp. 13182-13187
    • Sun, Y.1    Jiang, X.2    Chen, S.3    Fernandes, N.4    Price, B.D.5
  • 42
    • 70449518412 scopus 로고    scopus 로고
    • Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60
    • doi:10.1038/ncb1982. PMID:19783983.
    • Sun, Y., Jiang, X., Xu, Y., Ayrapetov, M.K., Moreau, L.A., Whetstine, J.R., and Price, B.D. 2009. Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60. Nat. Cell Biol. 11(11): 1376-1382. doi:10.1038/ncb1982. PMID:19783983.
    • (2009) Nat. Cell Biol. , vol.11 , Issue.11 , pp. 1376-1382
    • Sun, Y.1    Jiang, X.2    Xu, Y.3    Ayrapetov, M.K.4    Moreau, L.A.5    Whetstine, J.R.6    Price, B.D.7
  • 43
    • 0033833810 scopus 로고    scopus 로고
    • Carboxyl-terminal region conserved among phosphoinositide-kinase-related kinases is indispensable for mTOR function in vivo and in vitro
    • doi:10.1046/j.1365-2443.2000.00365.x. PMID: 10971657.
    • Takahashi, T., Hara, K., Inoue, H., Kawa, Y., Tokunaga, C., Hidayat, S., et al. 2000. Carboxyl-terminal region conserved among phosphoinositide-kinase- related kinases is indispensable for mTOR function in vivo and in vitro. Genes Cells, 5(9): 765-775. doi:10.1046/j.1365-2443.2000.00365.x. PMID: 10971657.
    • (2000) Genes Cells , vol.5 , Issue.9 , pp. 765-775
    • Takahashi, T.1    Hara, K.2    Inoue, H.3    Kawa, Y.4    Tokunaga, C.5    Hidayat, S.6
  • 44
    • 0029890959 scopus 로고    scopus 로고
    • Ataxia-telangiectasia: Mutations in ATM cDNA detected by protein-truncation screening
    • PMID:8659541
    • Telatar, M., Wang, Z., Udar, N., Liang, T., Bernatowska-Matuszkiewicz, E., Lavin, M., et al. 1996. Ataxia-telangiectasia: mutations in ATM cDNA detected by protein-truncation screening. Am. J. Hum. Genet. 59(1): 40-44. PMID:8659541.
    • (1996) Am. J. Hum. Genet. , vol.59 , Issue.1 , pp. 40-44
    • Telatar, M.1    Wang, Z.2    Udar, N.3    Liang, T.4    Bernatowska-Matuszkiewicz, E.5    Lavin, M.6
  • 45
    • 0038745419 scopus 로고    scopus 로고
    • Contributions of ATM mutations to familial breast and ovarian cancer
    • PMID:12810666.
    • Thorstenson, Y.R., Roxas, A., Kroiss, R., Jenkins, M.A., Yu, K.M., Bachrich, T., et al. 2003. Contributions of ATM mutations to familial breast and ovarian cancer. Cancer Res. 63(12): 3325-3333. PMID:12810666.
    • (2003) Cancer Res. , vol.63 , Issue.12 , pp. 3325-3333
    • Thorstenson, Y.R.1    Roxas, A.2    Kroiss, R.3    Jenkins, M.A.4    Yu, K.M.5    Bachrich, T.6
  • 46
    • 0002576958 scopus 로고    scopus 로고
    • Histological techniques for the Drosophila eye. Part II: Adult
    • Edited by W. Sullivan, M. Ashburner, and R.S. Hawley. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • Wolff, T. 2000 Histological techniques for the Drosophila eye. Part II: Adult. In Drosophila protocols. Edited by W. Sullivan, M. Ashburner, and R.S. Hawley. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y. pp. 229-244.
    • (2000) Drosophila Protocols. , pp. 229-244
    • Wolff, T.1
  • 47
    • 20744436198 scopus 로고    scopus 로고
    • ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbsl
    • doi:10.1128/MCB.25.13.5363-5379.2005. PMID: 15964794.
    • You, Z., Chahwan, C., Bailis, J., Hunter, T., and Russell, P. 2005. ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbsl. Mol. Cell. Biol. 25(13): 5363-5379. doi:10.1128/MCB.25.13.5363-5379. 2005. PMID: 15964794.
    • (2005) Mol. Cell. Biol. , vol.25 , Issue.13 , pp. 5363-5379
    • You, Z.1    Chahwan, C.2    Bailis, J.3    Hunter, T.4    Russell, P.5
  • 48
    • 34249061716 scopus 로고    scopus 로고
    • The cloning and characterization of the histone acetyltransferase human homolog Dmel\TIP60 in Drosophila melanogaster: Dmel\TIP60 is essential for multicellular development
    • doi:10.1534/genetics.106.063685. PMID: 17179074.
    • Zhu, X., Singh, N., Donnelly, C., Boimel, P., and Elefant, F. 2007. The cloning and characterization of the histone acetyltransferase human homolog Dmel\TIP60 in Drosophila melanogaster: Dmel\TIP60 is essential for multicellular development. Genetics, 175(3): 1229-1240. doi:10.1534/genetics.106.063685. PMID: 17179074.
    • (2007) Genetics , vol.175 , Issue.3 , pp. 1229-1240
    • Zhu, X.1    Singh, N.2    Donnelly, C.3    Boimel, P.4    Elefant, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.