Matricellular proteins: A sticky affair with cancers

Journal of Oncology

Volumn , Issue , 2012, Pages

  Chong, Han Chung ^a   Tan, Chek Kun ^a   Huang, Royston Luke ^a   Tan, Nguan Soon ^a  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN; ANGIOPOIETIN LIKE 4 PROTEIN; BETA1 INTEGRIN; BETA5 INTEGRIN; CASPASE 3; CD36 ANTIGEN; CD47 ANTIGEN; CELL PROTEIN; CYSTEINE RICH PROTEIN 61; DICKKOPF 1 PROTEIN; FIBRONECTIN; HERMES ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 3; OSTEONECTIN; OSTEOPONTIN; PHOSPHATIDYLINOSITOL 3 KINASE; SMAD PROTEIN; STROMAL CELL DERIVED FACTOR 1; SYNDECAN 4; TENASCIN; THROMBOSPONDIN 1; THROMBOSPONDIN 2; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN RECEPTOR 2; VERY LATE ACTIVATION ANTIGEN 2; VERY LATE ACTIVATION ANTIGEN 6; VITRONECTIN; WNT PROTEIN;

ANGIOGENESIS; ANOIKIS; CANCER GROWTH; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; EPITHELIAL MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; HUMAN; IMMUNOSURVEILLANCE; IN VITRO STUDY; IN VIVO STUDY; METASTASIS; NEOPLASM; NONHUMAN; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT;

EID: 84858188758     PISSN: 16878450     EISSN: 16878469     Source Type: Journal    
DOI: 10.1155/2012/351089     Document Type: Review

References (194)

1. Joyce J. A., Pollard J. W., Microenvironmental regulation of metastasis Nature Reviews Cancer 2009 9 4 239 252
2. Chiodoni C., Colombo M. P., Sangaletti S., Matricellular proteins: from homeostasis to inflammation, cancer, and metastasis Cancer and Metastasis Reviews 2010 29 2 295 307
3. Bornstein P., Matricellular proteins: an overview Journal of Cell Communication and Signaling 2009 3 3-4 163 165
4. Bornstein P., Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1 Journal of Cell Biology 1995 130 3 503 506
5. Murphy-Ullrich J. E., The de-adhesive activity of matricellular proteins: is intermediate cell adhesion an adaptive state? Journal of Clinical Investigation 2001 107 7 785 790 (Pubitemid 32274027)
6. Larue L., Bellacosa A., Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3' kinase/AKT pathways Oncogene 2005 24 50 7443 7454 (Pubitemid 41637984)
7. Peinado H., Olmeda D., Cano A., Snail, ZEB and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nature Reviews Cancer 2007 7 6 415 428 (Pubitemid 46809165)
8. Alonso S. R., Tracey L., Ortiz P., Pérez-Gmez B., Palacios J., Polln M., Linares J., Serrano S., Sez-Castillo A. I., Snchez L., Pajares R., Snchez-Aguilera A., Artiga M. J., Piris M. A., Rodrguez-Peralto J. L., A high-throughput study in melanoma identifies epithelial-mesenchymal transition as a major determinant of metastasis Cancer Research 2007 67 7 3450 3460 (Pubitemid 46724886)
9. Robert G., Gaggioli C., Bailet O., Chavey C., Abbe P., Aberdam E., Sabatié E., Cano A., Garcia De Herreros A., Ballotti R., Tartare-Deckert S., SPARC represses E-cadherin and induces mesenchymal transition during melanoma development Cancer Research 2006 66 15 7516 7523 (Pubitemid 44289206)
10. Van Marck V., Stove C., Van Den Bossche K., Stove V., Paredes J., Vander Haeghen Y., Bracke M., P-cadherin promotes cell-cell adhesion and counteracts invasion in human melanoma Cancer Research 2005 65 19 8774 8783 (Pubitemid 41379401)
11. Hannigan G., Troussard A. A., Dedhar S., Integrin-linked kinase: a cancer therapeutic target unique among its ILK Nature Reviews Cancer 2005 5 1 51 63 (Pubitemid 40052325)
12. Barker T. H., Baneyx G., Card-Vila M., Workman G. A., Weaver M., Menon P. M., Dedhar S., Rempel S. A., Arap W., Pasqualini R., Vogel V., Sage E. H., SPARC regulates extracellular matrix organization through its modulation of integrin-linked kinase activity Journal of Biological Chemistry 2005 280 43 36483 36493 (Pubitemid 41633922)
13. De S., Chen J., Narizhneva N. V., Heston W., Brainard J., Sage E. H., Byzova T. V., Molecular pathway for cancer metastasis to bone Journal of Biological Chemistry 2003 278 40 39044 39050 (Pubitemid 37221807)
14. Furger K. A., Menon R. K., Tuck A. B., Bramwel V. H. C., Chambers A. F., The functional and clinical roles of osteopontin in cancer and metastasis Current Molecular Medicine 2001 1 5 621 632 (Pubitemid 33772040)
15. Singhai H., Bautista D. S., Tonkin K. S., O'Malley F. P., Tuck A. B., Chambers A. F., Harris J. F., Elevated plasma osteopontin in metastatic breast cancer associated with increased tumor burden and decreased survival Clinical Cancer Research 1997 3 4 605 611 (Pubitemid 27211840)
16. Thalmann G. N., Sikes R. A., Devoll R. E., Kiefer J. A., Markwalder R., Klima I., Farach-Carson C. M., Studer U. E., Chung L. W.K., Osteopontin: possible role in prostate cancer progression Clinical Cancer Research 1999 5 8 2271 2277 (Pubitemid 29399287)
17. Chambers A. F., Wilson S. M., Kerkvliet N., O'Malley F. P., Harris J. F., Casson A. G., Osteopontin expression in lung cancer Lung Cancer 1996 15 3 311 323 (Pubitemid 26399511)
18. Agrawal D., Chen T., Irby R., Quackenbush J., Chambers A. F., Szabo M., Cantor A., Coppola D., Yeatman T. J., Osteopontin identified as lead marker of colon cancer progression, using pooled sample expression profiling Journal of the National Cancer Institute 2002 94 7 513 521 (Pubitemid 34411290)
19. Goparaju C. M. V., Pass H. I., Blasberg J. D., Hirsch N., Donington J. S., Functional heterogeneity of osteopontin isoforms in non-small cell lung cancer Journal of Thoracic Oncology 2010 5 10 1516 1523
20. Holbourn K. P., Acharya K. R., Perbal B., The CCN family of proteins: structure-function relationships Trends in Biochemical Sciences 2008 33 10 461 473
21. Perbal B., CCN proteins: multifunctional signalling regulators The Lancet 2004 363 9402 62 64 (Pubitemid 38076928)
22. Xie D., Yin D., Tong X., O'Kelly J., Mori A., Miller C., Black K., Gui D., Said J. W., Koeffler H. P., Cyr61 is overexpressed in gliomas and involved in integrin-linked kinase-mediated akt and -catenin-TCF/Lef signaling pathways Cancer Research 2004 64 6 1987 1996 (Pubitemid 38339444)
23. Haque I., Mehta S., Majumder M., Dhar K., De A., McGregor D., Van Veldhuizen P. J., Banerjee S. K., Banerjee S., Cyr61/CCN1 signaling is critical for epithelial-mesenchymal transition and stemness and promotes pancreatic carcinogenesis Molecular Cancer 2011 10, article 8
24. Sun Z. J., Wang Y., Cai Z., Chen P. P., Tong X. J., Xie D., Involvement of Cyr61 in growth, migration, and metastasis of prostate cancer cells British Journal of Cancer 2008 99 10 1656 1667
25. Tsai M. S., Bogart D. F., Castaeda J. M., Li P., Lupu R., Cyr61 promotes breast tumorigenesis and cancer progression Oncogene 2002 21 53 8178 8185 (Pubitemid 35454421)
26. Huang W., Gonzalez M. E., Toy K. A., Banerjee M., Kleer C. G., Blockade of CCN6 (WISP3) activates growth factor-independent survival and resistance to anoikis in human mammary epithelial cells Cancer Research 2010 70 8 3340 3350
27. Huang W., Zhang Y., Varambally S., Chinnaiyan A. M., Banerjee M., Merajver S. D., Kleer C. G., Inhibition of CCN6 (Wnt-1-induced signaling protein 3) down-regulates E-cadherin in the breast epithelium through induction of snail and ZEB1 American Journal of Pathology 2008 172 4 893 904 (Pubitemid 351519987)
28. Kleer C. G., Zhang Y., Pan Q., Van Golen K. L., Wu Z. F., Livant D., Merajver S. D., WISP3 is a novel tumor suppressor gene of inflammatory breast cancer Oncogene 2002 21 20 3172 3180 (Pubitemid 34552242)
29. Zhang Y., Pan Q., Zhong H., Merajver S. D., Kleer C. G., Inhibition of CCN6 (WISP3) expression promotes neoplastic progression and enhances the effects of insulin-like growth factor-1 on breast epithelial cells Breast Cancer Research 2005 7 6 R1080 R1089
30. Lorenzatti G., Huang W., Pal A., Cabanillas A. M., Kleer C. G., CCN6 (WISP3) decreases ZEB1-mediated EMT and invasion by attenuation of IGF-1 receptor signaling in breast cancer Journal of Cell Science 2011 124 10 1752 1758
31. Chiquet-Ehrismann R., Hagios C., Matsumoto K., The tenascin gene family Perspectives on Developmental Neurobiology 1994 2 1 3 7
32. Orend G., Chiquet-Ehrismann R., Tenascin-C induced signaling in cancer Cancer Letters 2006 244 2 143 163 (Pubitemid 44508708)
33. Midwood K. S., Orend G., The role of tenascin-C in tissue injury and tumorigenesis Journal of Cell Communication and Signaling 2009 3 3-4 287 310
34. Fukunaga-Kalabis M., Martinez G., Nguyen T. K., Kim D., Santiago-Walker A., Roesch A., Herlyn M., Tenascin-C promotes melanoma progression by maintaining the ABCB5-positive side population Oncogene 2010 29 46 6115 6124
35. Nagaharu K., Zhang X., Yoshida T., Katoh D., Hanamura N., Kozuka Y., Ogawa T., Shiraishi T., Imanaka-Yoshida K., Tenascin C induces epithelial-mesenchymal transition-like change accompanied by SRC activation and focal adhesion kinase phosphorylation in human breast cancer cells American Journal of Pathology 2011 178 2 754 763
36. Framson P. E., Sage E. H., SPARC and tumor growth: where the seed meets the soil? Journal of Cellular Biochemistry 2004 92 4 679 690 (Pubitemid 44264259)
37. Socha M. J., Said N., Dai Y., Kwong J., Ramalingam P., Trieu V., Desai N., Mok S. C., Motamed K., Aberrant promoter methulation of sparc in ovarian cancer Neoplasia 2009 11 2 126 135
38. Mok S. C., Chan W. Y., Wong K. K., Muto M. G., Berkowitz R. S., SPARC, an extracellular matrix protein with tumor-suppressing activity in human ovarian epithelial cells Oncogene 1996 12 9 1895 1901 (Pubitemid 26154661)
39. Huck-Hui N., Bird A., DNA methylation and chromatin modification Current Opinion in Genetics and Development 1999 9 2 158 163 (Pubitemid 29158549)
40. Nakanishi H., Oguri K., Takenaga K., Hosoda S., Okayama M., Differential fibrotic stromal responses of host tissue to low-and high-metastatic cloned Lewis lung carcinoma cells Laboratory Investigation 1994 70 3 324 332 (Pubitemid 24116526)
41. Sasaki T., Hohenester E., Ghring W., Timpl R., Crystal structure and mapping by site-directed mutagenesis of the collagen-binding epitope of an activated form of BM-40/SPARC/osteonectin EMBO Journal 1998 17 6 1625 1634 (Pubitemid 28119116)
42. Sasaki T., Miosge N., Timpl R., Immunochemical and tissue analysis of protease generated neoepitopes of BM-40 (osteonectin, SPARC) which are correlated to a higher affinity binding to collagens Matrix Biology 1999 18 5 499 508
43. Haber C. L., Gottifredi V., Llera A. S., Salvatierra E., Prada F., Alonso L., Helene S. E., Podhajcer O. L., SPARC modulates the proliferation of stromal but not melanoma cells unless endogenous SPARC expression is downregulated International Journal of Cancer 2008 122 7 1465 1475 (Pubitemid 351294954)
44. Menendez J. A., Vellon L., Mehmi I., Teng P. K., Griggs D. W., Lupu R., A novel CYR61-triggered CYR61- v 3 integrin loop regulates breast cancer cell survival and chemosensitivity through activation of ERK1/ERK2 MAPK signaling pathway Oncogene 2005 24 5 761 779 (Pubitemid 40216085)
45. Dobroff A. S., Wang H., Melnikova V. O., Villares G. J., Zigler M., Huang L., Bar-Eli M., Silencing cAMP-response element-binding protein (CREB) identifies CYR61 as a tumor suppressor gene in melanoma Journal of Biological Chemistry 2009 284 38 26194 26205
46. Huang W., Chiquet-Ehrismann R., Moyano J. V., Garcia-Pardo A., Orend G., Interference of tenascin-C with syndecan-4 binding to fibronectin blocks cell adhesion and stimulates tumor cell proliferation Cancer Research 2001 61 23 8586 8594 (Pubitemid 33131143)
47. Ruiz C., Huang W., Hegi M. E., Lange K., Hamou M. F., Fluri E., Oakeley E. J., Chiquet-Ehrismann R., Orend G., Differential gene expression analysis reveals activation of growth promoting signaling pathways by tenascin-C Cancer Research 2004 64 20 7377 7385 (Pubitemid 39372077)
48. Jinnin M., Ihn H., Asano Y., Yamane K., Trojanowska M., Tamaki K., Tenascin-C upregulation by transforming growth factor- in human dermal fibroblasts involves Smad3, Sp1, and Ets1 Oncogene 2004 23 9 1656 1667 (Pubitemid 38445158)
49. Oskarsson T., Acharyya S., Zhang X. H.-F., Vanharanta S., Tavazoie S. F., Morris P. G., Downey R. J., Manova-Todorova K., Brogi E., Massagué J., Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs Nature Medicine 2011 17 7 867 874
50. Pancewicza J., Taylora J. M., Dattaa A., Baydouna H. H., Waldmann T. A., Herminec O., Nicota C., Notch signaling contributes to proliferation and tumor formation of human T-cell leukemia virus type 1Associated adult T-cell leukemia Proceedings of the National Academy of Sciences of the United States of America 2010 107 38 16619 16624
51. Schlange T., Matsuda Y., Lienhard S., Huber A., Hynes N. E., Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation Breast Cancer Research 2007 9 5 R63
52. Cook A. C., Tuck A. B., McCarthy S., Turner J. G., Irby R. B., Bloom G. C., Yeatman T. J., Chambers A. F., Osteopontin induces multiple changes in gene expression that reflect the six hallmarks of cancer in a model of breast cancer progression Molecular Carcinogenesis 2005 43 4 225 236 (Pubitemid 41134430)
53. Rudland P. S., Platt-Higgins A., El-Tanani M., De Silva Rudland S., Barraclough R., Winstanley J. H. R., Howitt R., West C. R., Prognostic significance of the metastasis-associated protein osteopontin in human breast cancer Cancer Research 2002 62 12 3417 3427 (Pubitemid 34651388)
54. Bramwell V. H. C., Doig G. S., Tuck A. B., Wilson S. M., Tonkin K. S., Tomiak A., Perera F., Vandenberg T. A., Chambers A. F., Serial plasma osteopontin levels have prognostic value in metastatic breast cancer Clinical Cancer Research 2006 12 11 I 3337 3343
55. Zhao B., Sun T., Meng F., Qu A., Li C., Shen H., Jin Y., Li W., Osteopontin as a potential biomarker of proliferation and invasiveness for lung cancer Journal of Cancer Research and Clinical Oncology 2011 137 7 1061 1070
56. Kersten S., Mandard S., Tan N. S., Escher P., Metzger D., Chambon P., Gonzalez F. J., Desvergne B., Wahli W., Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene Journal of Biological Chemistry 2000 275 37 28488 28493
57. Cliff Yoon J., Chickering T. W., Rosen E. D., Dussault B., Qin Y., Soukas A., Friedman J. M., Holmes W. E., Spiegelman B. M., Peroxisome proliferator-activated receptor target gene encoding a novel angiopoietin-related protein associated with adipose differentiation Molecular and Cellular Biology 2000 20 14 5343 5349 (Pubitemid 30431587)
58. Xu A., Lam M. C., Chan K. W., Wang Y., Zhang J., Boo R. L. C., Xu J. Y., Chen B., Chow W. S., Tso A. W. K., Lam K. S. L., Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice Proceedings of the National Academy of Sciences of the United States of America 2005 102 17 6086 6091 (Pubitemid 40594259)
59. Goh Y. Y., Pal M., Chong H. C., Zhu P., Tan M. J., Punugu L., Tan C. K., Huang R. L., Sze S. K., Tang M. B. Y., Ding J. L., Kersten S., Tan N. S., Angiopoietin-like 4 interacts with matrix proteins to modulate wound healing Journal of Biological Chemistry 2010 285 43 32999 33009
60. Goh Y. Y., Pal M., Chong H. C., Zhu P., Tan M. J., Punugu L., Lam C. R. I., Yau Y. H., Tan C. K., Huang R. L., Tan S. M., Tang M. B. Y., Ding J. L., Kersten S., Tan N. S., Angiopoietin-like 4 interacts with integrins 1 and 5 to modulate keratinocyte migration American Journal of Pathology 2010 177 6 2791 2803
61. Kim S., Park Y., Kim S., Lee J., Wang D., Dubois R., ANGPTL4 induction by prostaglandin E 2 under hypoxic conditions promotes colorectal cancer progression Cancer Research 2011 71 7010
62. Verine J., Lehmann-Che J., Soliman H., Feugeas J. P., Vidal J., Mongiat-Artus P., Belhadj S., Philippe J., Lesage M., Wittmer E., Chanel S., Couvelard A., Ferlicot S., Rioux-Leclercq N., Vignaud J. M., Janin A., Germain S., Determination of angptl4 mRNA as a diagnostic marker of primary and metastatic clear cell renal-cell carcinoma PLoS ONE 2010 5 4
63. Zhu P., Tan M., Huang R.-L., Tan C., Chong H., Pal M., Lam C., Boukamp P., Pan J., Tan S., Kersten S., Li H., Ding J., Tan N., Angiopoietin-like 4 protein elevates the prosurvival intracellular O 2 -:H 2 O 2 ratio and confers anoikis resistance to tumors Cancer Cell 2011 19 3 401 415
64. Zetter B. R., Angiogenesis and tumor metastasis Annual Review of Medicine 1998 49 407 424 (Pubitemid 28197463)
65. Verheul H. M. W., Voest E. E., Schlingemann R. O., Are tumours angiogenesis-dependent? Journal of Pathology 2004 202 1 5 13 (Pubitemid 38072840)
66. Folkman J., Merler E., Abernathy C., Williams G., Isolation of a tumor factor responsible or angiogenesis Journal of Experimental Medicine 1971 133 2 275 288
67. Ribatti D., Vacca A., Presta M., The discovery of angiogenic factors: a historical review General Pharmacology 2000 35 5 227 231 (Pubitemid 34215114)
68. Schlingemann R. O., Rietveld F. J. R., De Waal R. M. W., Ferrone S., Ruiter D. J., Expression of the high molecular weight melanoma-associated antigen by pericytes during angiogenesis in tumors and in healing wounds American Journal of Pathology 1990 136 6 1393 1405 (Pubitemid 20210338)
69. Bingle L., Brown N. J., Lewis C. E., The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies Journal of Pathology 2002 196 3 254 265 (Pubitemid 34189413)
70. Schlingemann R. O., Oosterwijk E., Wesseling P., Rietveld F. J. R., Ruiter D. J., Aminopeptidase A is a constituent of activated pericytes in angiogenesis Journal of Pathology 1996 179 4 436 442 (Pubitemid 26276116)
71. Chen Y., Du X. Y., Functional properties and intracellular signaling of CCN1/Cyr61 Journal of Cellular Biochemistry 2007 100 6 1337 1345 (Pubitemid 46515568)
72. Chen C. C., Lau L. F., Functions and mechanisms of action of CCN matricellular proteins International Journal of Biochemistry and Cell Biology 2009 41 4 771 783
73. Xie D., Miller C. W., O'Kelly J., Nakachi K., Sakashita A., Said J. W., Gornbein J., Koeffler H. P., Breast cancer: Cyr61 is overexpressed, estrogen-inducible, and associated with more advanced disease Journal of Biological Chemistry 2001 276 17 14187 14194
74. Tsai M. S., Bogart D. F., Li P., Mehmi I., Lupu R., Expression and regulation of Cyr61 in human breast cancer cell lines Oncogene 2002 21 6 964 973 (Pubitemid 34146310)
75. Lin M. T., Chang C. C., Chen S. T., Chang H. L., Su J. L., Chau Y. P., Kuo M. L., Cyr61 expression confers resistance to apoptosis in breast cancer MCF-7 cells by a mechanism of NF- B-dependent XIAP up-regulation Journal of Biological Chemistry 2004 279 23 24015 24023
76. Mo F. E., Muntean A. G., Chen C. C., Stolz D. B., Watkins S. C., Lau L. F., CYR61 (CCN1) is essential for placental development and vascular integrity Molecular and Cellular Biology 2002 22 24 8709 8720 (Pubitemid 35397184)
77. Leu S. J., Lam S. C. T., Lau L. F., Pro-angiogenic activities of CYR61 (CCN1) mediated through integrins v 3 and 6 1 in human umbilical vein endothelial cells Journal of Biological Chemistry 2002 277 48 46248 46255
78. Menéndez J. A., Mehmi I., Griggs D. W., Lupu R., The angiogenic factor CYR61 in breast cancer: molecular pathology and therapeutic perspectives Endocrine-Related Cancer 2003 10 2 141 152 (Pubitemid 36758643)
79. Weber G. F., The metastasis gene osteopontin: a candidate target for cancer therapy Biochimica et Biophysica Acta 2001 1552 2 61 85 (Pubitemid 34124131)
80. Denhardt D. T., Noda M., O'Regan A. W., Pavlin D., Berman J. S., Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival Journal of Clinical Investigation 2001 107 9 1055 1061 (Pubitemid 32422899)
81. Takahashi F., Akutagawa S., Fukumoto H., Tsukiyama S., Ohe Y., Takahashi K., Fukuchi Y., Saijo N., Nishio K., Osteopontin induces angiogenesis of murine neuroblastoma cells in mice International Journal of Cancer 2002 98 5 707 712 (Pubitemid 34225620)
82. Chakraborty G., Jain S., Kundu G. C., Osteopontin promotes vascular endothelial growth factor-dependent breast tumor growth and angiogenesis via autocrine and paracrine mechanisms Cancer Research 2008 68 1 152 161 (Pubitemid 351380116)
83. Shevde L. A., Das S., Clark D. W., Samant R. S., Osteopontin: an effector and an effect of tumor metastasis Current Molecular Medicine 2010 10 1 71 81
84. Tanaka K., Hiraiwa N., Hashimoto H., Yamazaki Y., Kusakabe M., Tenascin-C regulates angiogenesis in tumor through the regulation of vascular endothelial growth factor expression International Journal of Cancer 2004 108 1 31 40 (Pubitemid 37444440)
85. Jallo G. I., Friedlander D. R., Kelly P. J., Wisoff J. H., Grumet M., Zagzag D., Tenascin-C expression in the cyst wall and fluid of human brain tumors correlates with angiogenesis Neurosurgery 1997 41 5 1052 1059 (Pubitemid 27475465)
86. Schenk S., Chiquet-Ehrismann R., Battegay E. J., The fibrinogen globe of tenascin-C promotes basic fibroblast growth factor-induced endothelial cell elongation Molecular Biology of the Cell 1999 10 9 2933 2943 (Pubitemid 29441573)
87. Bornstein P., Thrombospondins function as regulators of angiogenesis Journal of Cell Communication and Signaling 2009 3 3-4 189 200
88. Armstrong L. C., Bjrkblom B., Hankenson K. D., Siadak A. W., Stiles C. E., Bornstein P., Thrombospondin 2 inhibits microvascular endothelial cell proliferation by a caspase-independent mechanism Molecular Biology of the Cell 2002 13 6 1893 1905 (Pubitemid 34651480)
89. Armstrong L. C., Bornstein P., Thrombospondins 1 and 2 function as inhibitors of angiogenesis Matrix Biology 2003 22 1 63 71 (Pubitemid 36444508)
90. Tuszynski G. P., Gasic T. B., Rothman V. L., Thrombospondin, a potentiator of tumor cell metastasis Cancer Research 1987 47 15 4130 4133 (Pubitemid 17108482)
91. Campbell S. C., Volpert O. V., Ivanovich M., Bouck N. P., Molecular mediators of angiogenesis in bladder cancer Cancer Research 1998 58 6 1298 1304 (Pubitemid 28183222)
92. Isenberg J. S., Ridnour L. A., Perruccio E. M., Espey M. G., Wink D. A., Roberts D. D., Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner Proceedings of the National Academy of Sciences of the United States of America 2005 102 37 13141 13146 (Pubitemid 41324992)
93. Ignarro L. J., Nitric oxide as a unique signaling molecule in the vascular system: a historical overview Journal of Physiology and Pharmacology 2002 53 4 I 503 514 (Pubitemid 36014797)
94. Harpel J. G., Schultz-Cherry S., Murphy-Ullrich J. E., Rifkin D. B., Tamoxifen and estrogen effects on TGF- formation: role of thrombospondin-1, v 3, and integrin-associated protein Biochemical and Biophysical Research Communications 2001 284 1 11 14 (Pubitemid 32924301)
95. Hanamura N., Yoshida T., Matsumoto E. I., Kawarada Y., Sakakura T., Expression of fibronectin and tenascin-C mRNA by myofibroblasts, vascular cells and epithelial cells in human colon adenomas and carcinomas International Journal of Cancer 1997 73 1 10 15 (Pubitemid 27445983)
96. Short S. M., Derrien A., Narsimhan R. P., Lawler J., Ingber D. E., Zetter B. R., Inhibition of endothelial cell migration by thrombospondin-1 type-1 repeats is mediated by 1 integrins Journal of Cell Biology 2005 168 4 643 653 (Pubitemid 40271029)
97. Isenberg J. S., Martin-Manso G., Maxhimer J. B., Roberts D. D., Regulation of nitric oxide signalling by thrombospondin 1: implications for anti-angiogenic therapies Nature Reviews Cancer 2009 9 3 182 194
98. Nicosia R. F., Tuszynski G. P., Matrix-bound thrombospondin promotes angiogenesis in vitro Journal of Cell Biology 1994 124 1-2 183 193 (Pubitemid 24054620)
99. Staniszewska I., Zaveri S., Valle L. D., Oliva I., Rothman V. L., Croul S. E., Roberts D. D., Mosher D. F., Tuszynski G. P., Marcinkiewicz C., Interaction of 9 1 integrin with thrombospondin-1 promotes angiogenesis Circulation Research 2007 100 9 1308 1316 (Pubitemid 46742921)
100. Sprenger C. C., Plymate S. R., Reed M. J., Extracellular influences on tumour angiogenesis in the aged host British Journal of Cancer 2008 98 2 250 255 (Pubitemid 351161245)
101. Bellahcene A., Castronovo V., Increased expression of osteonectin and osteopontin, two bone matrix proteins, in human breast cancer American Journal of Pathology 1995 146 1 95 100
102. Fernanda Ledda M., Adris S., Bravo A. I., Kairiyama C., Bover L., Chernajovsky Y., Mordoh J., Podhajcer O. L., Suppression of SPARC expression by antisense RNA abrogates the tumorigenicity of human melanoma cells Nature Medicine 1997 3 2 171 176 (Pubitemid 27064701)
103. Porte H., Chastre E., Prevot S., Nordlinger B., Empereur S., Basset P., Chambon P., Gespach C., Neoplastic progression of human colorectal cancer is associated with overexpression of the stromelysin-3 and BM-40/SPARC genes International Journal of Cancer 1995 64 1 70 75
104. Rempel S. A., Ge S., Gutiérrez J. A., SPARC: a potential diagnostic marker of invasive meningiomas Clinical Cancer Research 1999 5 2 237 241 (Pubitemid 29085174)
105. Chlenski A., Liu S., Crawford S. E., Volpert O. V., DeVries G. H., Evangelista A., Yang Q., Salwen H. R., Farrer R., Bray J., Cohn S. L., SPARC is a key Schwannian-derived inhibitor controlling neuroblastoma tumor angiogenesis Cancer Research 2002 62 24 7357 7363 (Pubitemid 36032697)
106. Lau C. P. Y., Poon R. T. P., Cheung S. T., Yu W. C., Fan S. T., SPARC and Hevin expression correlate with tumour angiogenesis in hepatocellular carcinoma Journal of Pathology 2006 210 4 459 468
107. Shankavaram U. T., DeWitt D. L., Funk S. E., Sage E. H., Wahl L. M., Regulation of human monocyte matrix metalloproteinases by SPARC Journal of Cellular Physiology 1997 173 3 327 334 (Pubitemid 27481089)
108. Chlenski A., Guerrero L. J., Peddinti R., Spitz J. A., Leonhardt P. T., Yang Q., Tian Y., Salwen H. R., Cohn S. L., Anti-angiogenic SPARC peptides inhibit progression of neuroblastoma tumors Molecular Cancer 2010 9, article 138
109. Wang Z., Han B., Zhang Z., Pan J., Xia H., Expression of angiopoietin-like 4 and tenascin C but not cathepsin C mRNA predicts prognosis of oral tongue squamous cell carcinoma Biomarkers 2010 15 1 39 46
110. Toshiyuki N., Hiroshi H., Kenichiro S., Arifa N., Kuniko A., Takeshi N. A., Takashi T., Expression of angiopoietin-like 4 (ANGPTL4) in human colorectal cancer: ANGPTL4 promotes venous invasion and distant metastasis Oncology Reports 2011 25 4 929 935
111. Shibata K., Nakayama T., Hirakawa H., Hidaka S., Nagayasu T., Clinicopathological significance of angiopoietin-like protein 4 expression in oesophageal squamous cell carcinoma Journal of Clinical Pathology 2010 63 12 1054 1058
112. Kim I., Kim H. G., Kim H., Kim H. H., Park S. K., Uhm C. S., Lee Z. H., Koh G. Y., Hepatic expression, synthesis and secretion of a novel fibrinogen/angiopoietin-related protein that prevents endothelial-cell apoptosis Biochemical Journal 2000 346 3 603 610 (Pubitemid 30171019)
113. Le Jan S., Amy C., Cazes A., Monnot C., Lamandé N., Favier J., Philippe J., Sibony M., Gasc J. M., Corvol P., Germain S., Angiopoietin-like 4 is a proangiogenic factor produced during ischemia and in conventional renal cell carcinoma American Journal of Pathology 2003 162 5 1521 1528 (Pubitemid 36512834)
114. Galaup A., Cazes A., Le Jan S., Philippe J., Connault E., Le Coz E., Mekid H., Mir L. M., Opolon P., Corvol P., Monnot C., Germain S., Angiopoietin-like 4 prevents metastasis through inhibition of vascular permeability and tumor cell motility and invasiveness Proceedings of the National Academy of Sciences of the United States of America 2006 103 49 18721 18726 (Pubitemid 44913477)
115. Ito Y., Oike Y., Yasunaga K., Hamada K., Miyata K., Matsumoto S. I., Sugano S., Tanihara H., Masuho Y., Suda T., Inhibition of angiogenesis and vascular leakiness by angiopoietin-related protein 4 Cancer Research 2003 63 20 6651 6657 (Pubitemid 37322943)
116. Huang R.-L., Teo Z., Chong H. C., Zhu P., Tan M. J., Tan C. K., Lam C. R. I., Sng M. K., Leong D. T. W., Tan S. M., Kersten S., Ding J. L., Li H. Y., Tan N. S., ANGPTL4 modulates vascular junction integrity by integrin signaling and disruption of intercellular VE-cadherin and claudin-5 clusters Blood 2011 118 14 3990 4002
117. Hillen F., Griffioen A. W., Tumour vascularization: sprouting angiogenesis and beyond Cancer and Metastasis Reviews 2007 26 3-4 489 502 (Pubitemid 350115123)
118. Chiang A. C., Massagué J., Molecular basis of metastasis New England Journal of Medicine 2008 359 26 2814 2823
119. Genda T., Sakamoto M., Ichida T., Asakura H., Hirohashi S., Loss of cell-cell contact is induced by integrin-mediated cell-substratum adhesion in highly-motile and highly-metastatic hepatocellular carcinoma cells Laboratory Investigation 2000 80 3 387 394 (Pubitemid 30167798)
120. Timar J., Trikha M., Szekeres K., Bazaz R., Tovari J., Silletti S., Raz A., Honn K. V., Autocrine motility factor signals integrin-mediated metastatic melanoma cell adhesion and invasion Cancer Research 1996 56 8 1902 1908 (Pubitemid 26118230)
121. Enns A., Korb T., Schlter K., Gassmann P., Spiegel H.-U., Senninger N., Mitjans F., Haier J., v 5-integrins mediate early steps of metastasis formation European Journal of Cancer 2005 41 7 1065 1072 (Pubitemid 40602860)
122. Sargiannidou I., Zhou J., Tuszynski G. P., The role of thrombospondin-1 in tumor progression Experimental Biology and Medicine 2001 226 8 726 733 (Pubitemid 32785967)
123. Brown L. F., Guidi A. J., Schnitt S. J., Van De Water L., Iruela-Arispe M. L., Yeo T.-K., Tognazzi K., Dvorak H. F., Vascular stroma formation in carcinoma in situ, invasive carcinoma, and metastatic carcinoma of the breast Clinical Cancer Research 1999 5 5 1041 1056 (Pubitemid 29233218)
124. Varani J., Riser B. L., Hughes L. A., Carey T. E., Fligiel S. E. G., Dixit V. M., Characterization of thrombospondin synthesis, secretion and cell surface expression by human tumor cells Clinical and Experimental Metastasis 1989 7 3 265 276 (Pubitemid 19093312)
125. Incardona F., Calvo F., Fauvel-Lafeve F., Legrand Y., Legrand C., Involvement of thrombospondin in the adherence of the human breast- adenocarcinoma cells: a possible role in the metastatic process International Journal of Cancer 1993 55 3 471 477 (Pubitemid 23300601)
126. Grossfeld G. D., Ginsberg D. A., Stein J. P., Bochner B. H., Esrig D., Groshen S., Dunn M., Nichols P. W., Taylor C. R., Skinner D. G., Cote R. J., Thrombospondin-1 expression in bladder cancer: association with p53 alterations, tumor angiogenesis, and tumor progression Journal of the National Cancer Institute 1997 89 3 219 227 (Pubitemid 27073759)
127. Weinstat-Saslow D. L., Zabrenetzky V. S., VanHoutte K., Frazier W. A., Roberts D. D., Steeg P. S., Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis Cancer Research 1994 54 24 6504 6511
128. Gao A. G., Lindberg F. P., Finn M. B., Blystone S. D., Brown E. J., Frazier W. A., Integrin-associated protein is a receptor for the C-terminal domain of thrombospondin Journal of Biological Chemistry 1996 271 1 21 24 (Pubitemid 26026555)
129. Wang X. Q., Lindberg F. P., Frazier W. A., Integrin-associated protein stimulates 2 1-dependent chemotaxis via Gi-mediated inhibition of adenylate cyclase and extracellular-regulated kinases Journal of Cell Biology 1999 147 2 389 399 (Pubitemid 29496346)
130. Albo D., Berger D. H., Wang T. N., Hu X., Rothman V., Tuszynski G. P., Thrombospondin-1 and transforming growth factor-beta l promote breast tumor cell invasion through up-regulation of the plasminogen/plasmin system Surgery 1997 122 2 493 499
131. Albo D., Rothman V. L., Roberts D. D., Tuszynski G. P., Tumour cell thrombospondn-1 regulates tumour cell adhesion and invasion through the urokinase plasminogen activator receptor British Journal of Cancer 2000 83 3 298 306 (Pubitemid 30453567)
132. De Wever O., Nguyen Q.-D., Van Hoorde L., Bracke M., Bruyneel E., Gespach C., Mareel M., Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent pro-invasive signals to human colon cancer cells through RhoA and Rac FASEB Journal 2004 18 9 1016 1018 (Pubitemid 39561510)
133. Iyer A. K. V., Tran K. T., Griffith L., Wells A., Cell surface restriction of EGFR by a tenascin cytotactin-encoded EGF-like repeat is preferential for motility-related signaling Journal of Cellular Physiology 2008 214 2 504 512 (Pubitemid 350309007)
134. Lange K., Kammerer M., Hegi M. E., Grotegut S., Dittmann A., Huang W., Fluri E., Yip G. W., Gtte M., Ruiz C., Orend G., Endothelin receptor type B counteracts tenascin-C-induced endothelin receptor type A-dependent focal adhesion and actin stress fiber disorganization Cancer Research 2007 67 13 6163 6173 (Pubitemid 47037497)
135. Bradshaw A. D., Sage E. H., SPARC, a matricellular protein that functions in cellular differentiation and tissue response to injury Journal of Clinical Investigation 2001 107 9 1049 1054 (Pubitemid 32422898)
136. Arnold S. A., Brekken R. A., SPARC: a matricellular regulator of tumorigenesis Journal of Cell Communication and Signaling 2009 3 3-4 255 273
137. Schultz C., Lemke N., Ge S., Golembieski W. A., Rempel S. A., Secreted protein acidic and rich in cysteine promotes glioma invasion and delays tumor growth in vivo Cancer Research 2002 62 21 6270 6277 (Pubitemid 35244481)
138. Rich J. N., Shi Q., Hjelmeland M., Cummings T. J., Kuan C. T., Bigner D. D., Counter C. M., Wang X. F., Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model Journal of Biological Chemistry 2003 278 18 15951 15957 (Pubitemid 36799713)
139. Prenzel K. L., Warnecke-Eberz U., Xi H., Brabender J., Baldus S. E., Bollschweiler E., Gutschow C. A., Hlscher A. H., Schneider P. M., Significant overexpression of SPARC/osteonectin mRNA in pancreatic cancer compared to cancer of the papilla of Vater Oncology Reports. 2006 15 5 1397 1401
140. Iacobuzio-Donahue C. A., Argani P., Hempen P. M., Jones J., Kern S. E., The desmoplastic response to infiltrating breast carcinoma: gene expression at the site of primary invasion and implications for comparisons between tumor types Cancer Research 2002 62 18 5351 5357 (Pubitemid 35024612)
141. Seno T., Harada H., Kohno S., Teraoka M., Inoue A., Ohnishi T., Downregulation of SPARC expression inhibits cell migration and invasion in malignant gliomas International Journal of Oncology 2009 34 3 707 715
142. Mayer U., Aumailley M., Mann K., Timpl R., Engel J., Calcium-dependent binding of basement membranbe protein BM-40 (osteonectin, SPARC) to basement membrane collagen type IV European Journal of Biochemistry 1991 198 1 141 150
143. Brekken R. A., Sage E. H., SPARC, a matricellular protein: at the crossroads of cell-matrix Matrix Biology 2000 19 7 569 580
144. Gilles C., Bassuk J. A., Pulyaeva H., Sage E. H., Foidart J. M., Thompson E. W., SPARC/osteonectin induces matrix metalloproteinase 2 activation in human breast cancer cell lines Cancer Research 1998 58 23 5529 5536 (Pubitemid 28551141)
145. Fujita T., Shiba H., Sakata M., Uchida Y., Nakamura S., Kurihara H., SPARC stimulates the synthesis of OPG/OCIF, MMP-2 and DNA in human periodontal ligament cells Journal of Oral Pathology and Medicine 2002 31 6 345 352
146. Shi Q., Bao S., Song L., Wu Q., Bigner D. D., Hjelmeland A. B., Rich J. N., Targeting SPARC expression decreases glioma cellular survival and invasion associated with reduced activities of FAK and ILK kinases Oncogene 2007 26 28 4084 4094 (Pubitemid 46920166)
147. Smit D. J., Gardiner B. B., Sturm R. A., Osteonectin downregulates E-cadherin, induces Osteopontin and Focal Adhesion Kinase activity stimulating an invasive melanoma phenotype International Journal of Cancer 2007 121 12 2653 2660 (Pubitemid 350136408)
148. Said N., Najwer I., Motamed K., Secreted protein acidic and rich in cysteine (SPARC) inhibits integrin-mediated adhesion and growth factor-dependent survival signaling in ovarian cancer American Journal of Pathology 2007 170 3 1054 1063 (Pubitemid 47339372)
149. Lin M. T., Zuon C. Y., Chang C. C., Chen S. T., Chen C. P., Lin B. R., Wang M. Y., Jeng Y. M., Chang K. J., Lee P. H., Chen W. J., Kuo M. L., Cyr61 induces gastric cancer cell motility/invasion via activation of the integrin/nuclear factor- B/cyclooxygenase-2 signaling pathway Clinical Cancer Research 2005 11 16 5809 5820
150. Lin B. R., Chang C. C., Chen L. R., Wu M. H., Wang M. Y., Kuo I. H., Chu C. Y., Chang K. J., Lee P. H., Chen W. J., Kuo M. L., Lin M. T., Cysteine-rich 61 (CCN1) enhances chemotactic migration, transendothelial cell migration, and intravasation by concomitantly up-regulating chemokine receptor 1 and 2 Molecular Cancer Research 2007 5 11 1111 1123
151. Lin M. T., Kuo I. H., Chang C. C., Chu C. Y., Chen H. Y., Lin B. R., Sureshbabu M., Shih H. J., Kuo M. L., Involvement of hypoxia-inducing factor-1 -dependent plasminogen activator inhibitor-1 up-regulation in Cyr61/CCN1-induced gastric cancer cell invasion Journal of Biological Chemistry 2008 283 23 15807 15815
152. Holst-Hansen C., Johannessen B., Hyer-Hansen G., Rmer J., Ellis V., Brnner N., Urokinase-type plasminogen activation in three human breast cancer cell lines correlates with their in vitro invasiveness Clinical and Experimental Metastasis 1996 14 3 297 307 (Pubitemid 26246575)
153. Minn A. J., Gupta G. P., Siegel P. M., Bos P. D., Shu W., Giri D. D., Viale A., Olshen A. B., Gerald W. L., Massagué J., Genes that mediate breast cancer metastasis to lung Nature 2005 436 7050 518 524 (Pubitemid 41112921)
154. Li H., Ge C., Zhao F., Yan M., Hu C., Jia D., Tian H., Zhu M., Chen T., Jiang G., Xie H., Cui Y., Gu J., Tu H., He X., Yao M., Liu Y., Li J., Hypoxia-inducible factor 1 alpha-activated angiopoietin-like protein 4 contributes to tumor metastasis via vascular cell adhesion molecule-1/integrin 1 signaling in human hepatocellular carcinoma Hepatology 2011 54 3 910 919
155. Padua D., Zhang X. H. F., Wang Q., Nadal C., Gerald W. L., Gomis R. R., Massagué J., TGF primes breast tumors for lung metastasis seeding through angiopoietin-like 4 Cell 2008 133 1 66 77 (Pubitemid 351442989)
156. Mehlen P., Puisieux A., Metastasis: a question of life or death Nature Reviews Cancer 2006 6 6 449 458
157. Hanahan D., Weinberg R. A., Hallmarks of cancer: the next generation Cell 2011 144 5 646 674
158. Llera A. S., Girotti M. R., Benedetti L. G., Podhajcer O. L., Matricellular proteins and inflammatory cells: a task force to promote or defeat cancer? Cytokine and Growth Factor Reviews 2010 21 1 67 76
159. Sangaletti S., Colombo M. P., Matricellular proteins at the crossroad of inflammation and cancer Cancer Letters 2008 267 2 245 253
160. Alvarez M. J., Prada F., Salvatierra E., Bravo A. I., Lutzky V. P., Carbone C., Pitossi F. J., Chuluyan H. E., Podhajcer O. L., Secreted protein acidic and rich in cysteine produced by human melanoma cells modulates polymorphonuclear leukocyte recruitment and antitumor cytotoxic capacity Cancer Research 2005 65 12 5123 5132 (Pubitemid 40827321)
161. Prada F., Benedetti L. G., Bravo A. I., Alvarez M. J., Carbone C., Podhajcer O. L., SPARC endogenous level, rather than fibroblast-produced SPARC or stroma reorganization induced by SPARC, is responsible for melanoma cell growth Journal of Investigative Dermatology 2007 127 11 2618 2628 (Pubitemid 47585072)
162. Weaver M. S., Workman G., Sage E. H., The copper binding domain of SPARC mediates cell survival in vitro via interaction with integrin 1 and activation of integrin-linked kinase Journal of Biological Chemistry 2008 283 33 22826 22837
163. Lupetti R., Mortarini R., Panceri P., Sensi M., Anichini A., Interaction with fibronectin regulates cytokine gene expression in human melanoma cells International Journal of Cancer 1996 66 1 110 116 (Pubitemid 26122326)
164. White E. S., Livant D. L., Markwart S., Arenberg D. A., Monocyte-fibronectin interactions, via 5 1 integrin, induce expression of CXC chemokine-dependent angiogenic activity Journal of Immunology 2001 167 9 5362 5366 (Pubitemid 33009776)
165. Crawford H. C., Matrisian L. M., Liaw L., Distinct roles of osteopontin in host defense activity and tumor survival during squamous cell carcinoma progression in vivo Cancer Research 1998 58 22 5206 5215 (Pubitemid 28521184)
166. Scatena M., Liaw L., Giachelli C. M., Osteopontin: a multifunctional molecule regulating chronic inflammation and vascular disease Arteriosclerosis, Thrombosis, and Vascular Biology 2007 27 11 2302 2309 (Pubitemid 350203943)
167. Nishimichi N., Hayashita-Kinoh H., Chen C., Matsuda H., Sheppard D., Yokosaki Y., Osteopontin undergoes polymerization in vivo and gains chemotactic activity for neutrophils mediated by integrin alpha9beta1 The Journal of Biological Chemistry 2011 286 13 11170 11178
168. Ramankulov A., Lein M., Kristiansen G., Loening S. A., Jung K., Plasma osteopontin in comparison with bone markers as indicator of bone metastasis and survival outcome in patients with prostate cancer Prostate 2007 67 3 330 340
169. Fedarko N. S., Jain A., Karadag A., Van Eman M. R., Fisher L. W., Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer Clinical Cancer Research 2001 7 12 4060 4066 (Pubitemid 34044628)
170. Hotte S. J., Winquist E. W., Stitt L., Wilson S. M., Chambers A. F., Plasma osteopontin: associations with survival and metastasis to bone in men with hormone-refractory prostate carcinoma Cancer 2002 95 3 506 512 (Pubitemid 34810175)
171. Rittling S. R., Chen Y., Feng F., Wu Y., Tumor-derived osteopontin is soluble, not matrix associated Journal of Biological Chemistry 2002 277 11 9175 9182 (Pubitemid 34952996)
172. Feng B., Rollo E. E., Denhardt D. T., Osteopontin (OPN) may facilitate metastasis by protecting cells from macrophage NO-mediated cytotoxicity: evidence from cell lines down-regulated for OPN expression by a targeted ribozyme Clinical and Experimental Metastasis 1995 13 6 453 462
173. Rollo E. E., Laskin D. L., Denhardt D. T., Osteopontin inhibits nitric oxide production and cytotoxicity by activated RAW264.7 macrophages Journal of Leukocyte Biology 1996 60 3 397 404 (Pubitemid 26325622)
174. Bourassa B., Monaghan S., Rittling S. R., Impaired anti-tumor cytotoxicity of macrophages from osteopontin-deficient mice Cellular Immunology 2004 227 1 1 11 (Pubitemid 38393724)
175. Takahashi K., Takahashi F., Hirama M., Tanabe K. K., Fukuchi Y., Restoration of CD44S in non-small cell lung cancer cells enhanced their susceptibility to the macrophage cytotoxicity Lung Cancer 2003 41 2 145 153 (Pubitemid 36842777)
176. Kulla A., Liigant A., Piirsoo A., Rippin G., Asser T., Tenascin expression patterns and cells of monocyte lineage: relationship in human gliomas Modern Pathology 2000 13 1 56 67 (Pubitemid 30077905)
177. Parekh K., Ramachandran S., Cooper J., Bigner D., Patterson A., Mohanakumar T., Tenascin-C, over expressed in lung cancer down regulates effector functions of tumor infiltrating lymphocytes Lung Cancer 2005 47 1 17 29 (Pubitemid 39643238)
178. Talts J. F., Wirl G., Dictor M., Muller W. J., Fssler R., Tenascin-C modulates tumor stroma and monocyte/macrophage recruitment but not tumor growth or metastasis in a mouse strain with spontaneous mammary cancer Journal of Cell Science 1999 112 12 1855 1864 (Pubitemid 29338811)
179. Hauzenberger D., Olivier P., Gundersen D., Regg C., Tenascin-C inhibits 1 integrin-dependent T lymphocyte adhesion to fibronectin through the binding of its fnIII 1-5 repeats to fibronectin European Journal of Immunology 1999 29 5 1435 1447 (Pubitemid 29224448)
180. Gundersen D., Trn-Thang C., Sordat B., Mourali F., Regg C., Plasmin-induced proteolysis of tenascin-C: modulation by T lymphocyte-derived urokinase-type plasminogen activator and effect on T lymphocyte adhesion, activation, and cell clustering Journal of Immunology 1997 158 3 1051 1060 (Pubitemid 127469924)
181. Riser B. L., Mitra R., Perry D., Dixit V., Varani J., Monocyte killing of human squamous epithelial cells: role for thrombospondin Cancer Research 1989 49 21 6123 6129 (Pubitemid 19274179)
182. Martin-Manso G., Galli S., Ridnour L. A., Tsokos M., Wink D. A., Roberts D. D., Thrombospondin 1 promotes tumor macrophage recruitment and enhances tumor cell cytotoxicity of differentiated U937 cells Cancer Research 2008 68 17 7090 7099
183. Agah A., Kyriakides T. R., Lawler J., Bornstein P., The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice American Journal of Pathology 2002 161 3 831 839 (Pubitemid 34988370)
184. Vallejo A. N., Mgge L. O., Klimiuk P. A., Weyand C. M., Goronzy J. J., Central role of thrombospondin-1 in the activation and clonal expansion of inflammatory T cells Journal of Immunology 2000 164 6 2947 2954 (Pubitemid 30148952)
185. Li S. S., Liu Z., Uzunel M., Sundqvist K. G., Endogenous thrombospondin-1 is a cell-surface ligand for regulation of integrin-dependent T-lymphocyte adhesion Blood 2006 108 9 3112 3120
186. Grimbert P., Bouguermouh S., Baba N., Nakajima T., Allakhverdi Z., Braun D., Saito H., Rubio M., Delespesse G., Sarfati M., Thrombospondin/CD47 interaction: a pathway to generate regulatory T cells-from human CD4+CD25-T cells in response to inflammation Journal of Immunology 2006 177 6 3534 3541 (Pubitemid 44359884)
187. Baumgartner J. M., Palmer B. E., Banerjee A., McCarter M. D., Role of melanoma secreted thrombospondin-1 on induction of immunosuppressive regulatory T cells through CD47 Journal of Cancer Molecules 2008 4 5 145 152
188. Schultz-Cherry S., Chen H., Mosher D. F., Misenheimer T. M., Krutzsch H. C., Roberts D. D., Murphy-Ullrich J. E., Regulation of transforming growth factor- activation by discrete sequences of thrombospondin 1 Journal of Biological Chemistry 1995 270 13 7304 7310
189. Tuck A. B., Chambers A. F., Allan A. L., Osteopontin overexpression in breast cancer: knowledge gained and possible implications for clinical management Journal of Cellular Biochemistry 2007 102 4 859 868 (Pubitemid 350036926)
190. Podhajcer O. L., Benedetti L. G., Girotti M. R., Prada F., Salvatierra E., Llera A. S., The role of the matricellular protein SPARC in the dynamic interaction between the tumor and the host Cancer and Metastasis Reviews 2008 27 4 691 705
191. Rusnati M., Urbinati C., Bonifacio S., Presta M., Taraboletti G., Thrombospondin-1 as a paradigm for the development of antiangiogenic agents endowed with multiple mechanisms of action Pharmaceuticals 2010 3 4 1241 1278
192. Furrer J., Luy B., Basrur V., Roberts D. D., Barchi J. J., Conformational analysis of an 3 1 integrin-binding peptide from thrombospondin-1: implications for antiangiogenic drug design Journal of Medicinal Chemistry 2006 49 21 6324 6333 (Pubitemid 44595209)
193. Orian-Rousseau V., CD44, a therapeutic target for metastasising tumours European Journal of Cancer 2010 46 7 1271 1277
194. Yin J., Chen G., Liu Y., Liu S., Wang P., Wan Y., Wang X., Zhu J., Gao H., Downregulation of SPARC expression decreases gastric cancer cellular invasion and survival Journal of Experimental and Clinical Cancer Research 2010 29 1, article 59