메뉴 건너뛰기




Volumn 168, Issue 4, 2005, Pages 643-653

Inhibition of endothelial cell migration by thrombospondin-1 type-1 repeats is mediated by β1 integrins

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; CD36 ANTIGEN; MEMBRANE RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C GAMMA; PROTEIN KINASE B; THROMBOSPONDIN 1; VASCULOTROPIN; VASCULOTROPIN INHIBITOR;

EID: 13944267041     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200407060     Document Type: Article
Times cited : (123)

References (67)
  • 2
    • 2542481699 scopus 로고    scopus 로고
    • The integrin β1 subunit transmembrane domain regulates phosphatidylinositol 3-kinase-dependent tyrosine phosphorylation of Crk-associated substrate
    • Armulik, A., T. Veiling, and S. Johansson. 2004. The integrin β1 subunit transmembrane domain regulates phosphatidylinositol 3-kinase-dependent tyrosine phosphorylation of Crk-associated substrate. Mol. Biol. Cell. 15:2558-2567.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 2558-2567
    • Armulik, A.1    Veiling, T.2    Johansson, S.3
  • 4
    • 0034739854 scopus 로고    scopus 로고
    • Activated R-ras, Racl, PI 3-kinase and PKCε can each restore cell spreading inhibited by isolated integrin β1 cytoplasmic domains
    • Berrier, A.L., A.M. Mastrangelo, J. Downward, M. Ginsberg, and S.E. La-Flamme. 2000. Activated R-ras, Racl, PI 3-kinase and PKCε can each restore cell spreading inhibited by isolated integrin β1 cytoplasmic domains. J. Cell Biol. 151:1549-1560.
    • (2000) J. Cell Biol. , vol.151 , pp. 1549-1560
    • Berrier, A.L.1    Mastrangelo, A.M.2    Downward, J.3    Ginsberg, M.4    La-Flamme, S.E.5
  • 5
    • 2942670657 scopus 로고    scopus 로고
    • Blockage of VEGF-induced angiogenesis by preventing VEGF secretion
    • Bjorndahl, M., R. Cao, A. Eriksson, and Y. Cao. 2004. Blockage of VEGF-induced angiogenesis by preventing VEGF secretion. Circ. Res. 94:1443-1450.
    • (2004) Circ. Res. , vol.94 , pp. 1443-1450
    • Bjorndahl, M.1    Cao, R.2    Eriksson, A.3    Cao, Y.4
  • 6
    • 0035049231 scopus 로고    scopus 로고
    • Thrombospondins as matricellular modulators of cell function
    • Bornstein, P. 2001. Thrombospondins as matricellular modulators of cell function. J. Clin. Invest. 107:929-934.
    • (2001) J. Clin. Invest. , vol.107 , pp. 929-934
    • Bornstein, P.1
  • 7
    • 0028362876 scopus 로고
    • Requirement of vascular integrin αvβ3 for angiogenesis
    • Brooks, P.C., R.A. Clark, and D.A. Cheresh. 1994. Requirement of vascular integrin αvβ3 for angiogenesis. Science. 264:569-571.
    • (1994) Science , vol.264 , pp. 569-571
    • Brooks, P.C.1    Clark, R.A.2    Cheresh, D.A.3
  • 10
  • 11
    • 0034492232 scopus 로고    scopus 로고
    • Cell contact-dependent activation of α3β1 integrin modulates endothelial cell responses to thrombospondin-1
    • Chandrasekaran, L., C.Z. He, H. Al-Barazi, H.C. Krutzsch, M.L. Iruela-Arispe, and D.D. Roberts. 2000. Cell contact-dependent activation of α3β1 integrin modulates endothelial cell responses to thrombospondin-1. Mol. Biol. Cell. 11:2885-2900.
    • (2000) Mol. Biol. Cell , vol.11 , pp. 2885-2900
    • Chandrasekaran, L.1    He, C.Z.2    Al-Barazi, H.3    Krutzsch, H.C.4    Iruela-Arispe, M.L.5    Roberts, D.D.6
  • 12
    • 0033734494 scopus 로고    scopus 로고
    • The cell biology of thrombospondin-1
    • Chen, H., M.E. Herndon, and J. Lawler. 2000. The cell biology of thrombospondin-1. Matrix Biol. 19:597-614.
    • (2000) Matrix Biol. , vol.19 , pp. 597-614
    • Chen, H.1    Herndon, M.E.2    Lawler, J.3
  • 13
    • 0026162515 scopus 로고
    • The integrin complex αvβ3 participates in the adhesion of microvascular endothelial cells to fibronectin
    • Cheng, Y.F., R.I. Clyman, J. Enenstein, N. Waleh, R. Pytela, and R.H. Kramer. 1991. The integrin complex αvβ3 participates in the adhesion of microvascular endothelial cells to fibronectin. Exp. Cell Res. 194:69-77.
    • (1991) Exp. Cell Res. , vol.194 , pp. 69-77
    • Cheng, Y.F.1    Clyman, R.I.2    Enenstein, J.3    Waleh, N.4    Pytela, R.5    Kramer, R.H.6
  • 14
    • 0026769440 scopus 로고
    • β1 and β3 integrins have different roles in the adhesion and migration of vascular smooth muscle cells on extracellular matrix
    • Clyman, R.I., F. Mauray, and R.H. Kramer. 1992. β1 and β3 integrins have different roles in the adhesion and migration of vascular smooth muscle cells on extracellular matrix. Exp. Cell Res. 200:272-284.
    • (1992) Exp. Cell Res. , vol.200 , pp. 272-284
    • Clyman, R.I.1    Mauray, F.2    Kramer, R.H.3
  • 15
    • 0032905431 scopus 로고    scopus 로고
    • Local delivery of TNF by retrovirus-transduced T lymphocytes exacerbates experimental autoimmune encephalomyelitis
    • Dal Canto, R.A., M.K. Shaw, G.P. Nolan, L. Steinman, and C.G. Fathman. 1999. Local delivery of TNF by retrovirus-transduced T lymphocytes exacerbates experimental autoimmune encephalomyelitis. Clin. Immunol. 90:10-14.
    • (1999) Clin. Immunol. , vol.90 , pp. 10-14
    • Dal Canto, R.A.1    Shaw, M.K.2    Nolan, G.P.3    Steinman, L.4    Fathman, C.G.5
  • 17
    • 0033027727 scopus 로고    scopus 로고
    • Three distinct D-amino acid substitutions confer potent antiangiogenic activity on an inactive peptide derived from a thrombospondin-1 type 1 repeat
    • Dawson, D.W., O.V. Volpert, S.F. Pearce, A.J. Schneider, R.L. Silverstein, J. Henkin, and N.P. Bouck. 1999. Three distinct D-amino acid substitutions confer potent antiangiogenic activity on an inactive peptide derived from a thrombospondin-1 type 1 repeat. Mol. Pharmacol. 55:332-338.
    • (1999) Mol. Pharmacol. , vol.55 , pp. 332-338
    • Dawson, D.W.1    Volpert, O.V.2    Pearce, S.F.3    Schneider, A.J.4    Silverstein, R.L.5    Henkin, J.6    Bouck, N.P.7
  • 18
    • 0034698284 scopus 로고    scopus 로고
    • Phosphorylation of the endothelial nitric oxide synthase at ser-1177 is required for VEGF-induced endothelial cell migration
    • Dimmeler, S., E. Dernbach, and A.M. Zeiher. 2000. Phosphorylation of the endothelial nitric oxide synthase at ser-1177 is required for VEGF-induced endothelial cell migration. FEBS Lett. 477:258-262.
    • (2000) FEBS Lett. , vol.477 , pp. 258-262
    • Dimmeler, S.1    Dernbach, E.2    Zeiher, A.M.3
  • 19
    • 0034747320 scopus 로고    scopus 로고
    • Thrombospondin-1, vascular endothelial growth factor and fibroblast growth factor-2 are key functional regulators of angiogenesis in the prostate
    • Doll, J.A., F.K. Reiher, S.E. Crawford, M.R. Pins, S.C. Campbell, and N.P. Bouck. 2001. Thrombospondin-1, vascular endothelial growth factor and fibroblast growth factor-2 are key functional regulators of angiogenesis in the prostate. Prostate. 49:293-305.
    • (2001) Prostate , vol.49 , pp. 293-305
    • Doll, J.A.1    Reiher, F.K.2    Crawford, S.E.3    Pins, M.R.4    Campbell, S.C.5    Bouck, N.P.6
  • 20
    • 2942590261 scopus 로고    scopus 로고
    • Vascular endothelial growth factor as a target for anticancer therapy
    • Ferrara, N. 2004. Vascular endothelial growth factor as a target for anticancer therapy. Oncologist. 9(Suppl 1):2-10.
    • (2004) Oncologist , vol.9 , Issue.SUPPL. 1 , pp. 2-10
    • Ferrara, N.1
  • 21
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman, J. 1995. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med. 1:27-31.
    • (1995) Nat. Med. , vol.1 , pp. 27-31
    • Folkman, J.1
  • 23
    • 0032515047 scopus 로고    scopus 로고
    • Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation
    • Gerber, H.P., A. McMurtrey, J. Kowalski, M. Yan, B.A. Keyt, V. Dixit, and N. Ferrara. 1998. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J. Biol. Chem. 273:30336-30343.
    • (1998) J. Biol. Chem. , vol.273 , pp. 30336-30343
    • Gerber, H.P.1    McMurtrey, A.2    Kowalski, J.3    Yan, M.4    Keyt, B.A.5    Dixit, V.6    Ferrara, N.7
  • 24
    • 0025147371 scopus 로고
    • A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin
    • Good, D.J., P.J. Polverini, F. Rastinejad, M.M. Le Beau, R.S. Lemons, W.A. Frazier, and N.P. Bouck. 1990. A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin. Proc. Natl. Acad. Sci. USA. 87:6624-6628.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 6624-6628
    • Good, D.J.1    Polverini, P.J.2    Rastinejad, F.3    Le Beau, M.M.4    Lemons, R.S.5    Frazier, W.A.6    Bouck, N.P.7
  • 25
    • 0033538832 scopus 로고    scopus 로고
    • Role of cholesterol in formation and function of a signaling complex involving αvβ3, integrin-associated protein (CD47), and heterotrinieric G proteins
    • Green, J.M., A. Zhelesnyak, J. Chung, F.P. Lindberg, M. Sarfati, W.A. Frazier, and E.J. Brown. 1999. Role of cholesterol in formation and function of a signaling complex involving αvβ3, integrin-associated protein (CD47), and heterotrinieric G proteins. J. Cell Biol. 146:673-682.
    • (1999) J. Cell Biol. , vol.146 , pp. 673-682
    • Green, J.M.1    Zhelesnyak, A.2    Chung, J.3    Lindberg, F.P.4    Sarfati, M.5    Frazier, W.A.6    Brown, E.J.7
  • 28
    • 0025372477 scopus 로고
    • Fibronectin controls capillary endothelial cell growth by modulating cell shape
    • Ingber, D.E. 1990. Fibronectin controls capillary endothelial cell growth by modulating cell shape. Proc. Natl. Acad. Sci. USA. 87:3579-3583.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 3579-3583
    • Ingber, D.E.1
  • 29
    • 0033613226 scopus 로고    scopus 로고
    • Inhibition of angiogenesis by thrombospondin-1 is mediated by 2 independent regions within the type 1 repeats
    • Iruela-Arispe, M.L., M. Lombardo, H.C. Krutzsch, J. Lawler, and D.D. Roberts. 1999. Inhibition of angiogenesis by thrombospondin-1 is mediated by 2 independent regions within the type 1 repeats. Circulation. 100:1423-1431.
    • (1999) Circulation , vol.100 , pp. 1423-1431
    • Iruela-Arispe, M.L.1    Lombardo, M.2    Krutzsch, H.C.3    Lawler, J.4    Roberts, D.D.5
  • 30
    • 0342445431 scopus 로고    scopus 로고
    • Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1
    • Jimenez, B., O.V. Volpert, S.E. Crawford, M. Febbraio, R.L. Silverstein, and N. Bouck. 2000. Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1. Nat. Med. 6:41-48.
    • (2000) Nat. Med. , vol.6 , pp. 41-48
    • Jimenez, B.1    Volpert, O.V.2    Crawford, S.E.3    Febbraio, M.4    Silverstein, R.L.5    Bouck, N.6
  • 31
    • 0033230597 scopus 로고    scopus 로고
    • Role of thrombospondin-1-derived peptide, 4N1K, in FGF-2-induced angiogenesis
    • Kanda, S., T. Shono, B. Tomasini-Johansson, P. Klint, and Y. Saito. 1999. Role of thrombospondin-1-derived peptide, 4N1K, in FGF-2-induced angiogenesis. Exp. Cell Res. 252:262-272.
    • (1999) Exp. Cell Res. , vol.252 , pp. 262-272
    • Kanda, S.1    Shono, T.2    Tomasini-Johansson, B.3    Klint, P.4    Saito, Y.5
  • 32
    • 0033843942 scopus 로고    scopus 로고
    • Regulation of angiogenesis in vivo by ligation of integrin α5β1 with the central cell-binding domain of fibronectin
    • Kim, S., K. Bell, S.A. Mousa, and J.A. Varner. 2000. Regulation of angiogenesis in vivo by ligation of integrin α5β1 with the central cell-binding domain of fibronectin. Am. J. Pathol. 156:1345-1362.
    • (2000) Am. J. Pathol. , vol.156 , pp. 1345-1362
    • Kim, S.1    Bell, K.2    Mousa, S.A.3    Varner, J.A.4
  • 33
    • 0034912850 scopus 로고    scopus 로고
    • Targeting of vasculature in cancer and other angiogenic diseases
    • Kumar, S., and C. Li. 2001. Targeting of vasculature in cancer and other angiogenic diseases. Trends Immunol. 22:129.
    • (2001) Trends Immunol. , vol.22 , pp. 129
    • Kumar, S.1    Li, C.2
  • 34
    • 0033924882 scopus 로고    scopus 로고
    • Opposing effects of hypoxia on expression of the angiogenic inhibitor thrombospondin 1 and the angiogenic inducer vascular endothelial growth factor
    • Laderoute, K.R., R.M. Alarcon, M.D. Brody, J.M. Calaoagan, E.Y. Chen, A.M. Knapp, Z. Yun, N.C. Denko, and A.J. Giaccia. 2000. Opposing effects of hypoxia on expression of the angiogenic inhibitor thrombospondin 1 and the angiogenic inducer vascular endothelial growth factor. Clin. Cancer Res. 6:2941-2950.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 2941-2950
    • Laderoute, K.R.1    Alarcon, R.M.2    Brody, M.D.3    Calaoagan, J.M.4    Chen, E.Y.5    Knapp, A.M.6    Yun, Z.7    Denko, N.C.8    Giaccia, A.J.9
  • 35
    • 0036362236 scopus 로고    scopus 로고
    • Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth
    • Lawler, J. 2002. Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth. J. Cell. Mol. Med. 6:1-12.
    • (2002) J. Cell. Mol. Med. , vol.6 , pp. 1-12
    • Lawler, J.1
  • 37
  • 38
    • 0035503689 scopus 로고    scopus 로고
    • Thrombospondin-1 type 1 repeat recombinant proteins inhibit tumor growth through transforming growth factor-β-dependent and -independent mechanisms
    • Miao, W.M., W.L. Seng, M. Duquette, P. Lawler, C. Laus, and J. Lawler. 2001. Thrombospondin-1 type 1 repeat recombinant proteins inhibit tumor growth through transforming growth factor-β-dependent and -independent mechanisms. Cancer Res. 61:7830-7839.
    • (2001) Cancer Res. , vol.61 , pp. 7830-7839
    • Miao, W.M.1    Seng, W.L.2    Duquette, M.3    Lawler, P.4    Laus, C.5    Lawler, J.6
  • 39
    • 0032587404 scopus 로고    scopus 로고
    • The engagement of β1 integrins on promonocytic cells promotes phosphorylation of Syk and formation of a protein complex containing Lyn and β1 integrin
    • Miller, L.A., J.J. Hong, M.S. Kinch, M.L. Harrison, and R.L. Geahlen. 1999. The engagement of β1 integrins on promonocytic cells promotes phosphorylation of Syk and formation of a protein complex containing Lyn and β1 integrin. Eur. J. Immunol. 29:1425-1434.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 1425-1434
    • Miller, L.A.1    Hong, J.J.2    Kinch, M.S.3    Harrison, M.L.4    Geahlen, R.L.5
  • 40
    • 0030453194 scopus 로고    scopus 로고
    • Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: Roles of integrin aggregation and occupancy of receptors
    • Miyamoto, S., H. Teramoto, J.S. Gutkind, and K.M. Yamada. 1996. Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors. J. Cell Biol. 135:1633-1642.
    • (1996) J. Cell Biol. , vol.135 , pp. 1633-1642
    • Miyamoto, S.1    Teramoto, H.2    Gutkind, J.S.3    Yamada, K.M.4
  • 41
    • 3843099220 scopus 로고    scopus 로고
    • Inhibition of α5 integrin decreases PI3K activation and cell adhesion of human colon cancers
    • Murillo, C.A., P.G. Rychahou, and B.M. Evers. 2004. Inhibition of α5 integrin decreases PI3K activation and cell adhesion of human colon cancers. Surgery. 136:143-149.
    • (2004) Surgery , vol.136 , pp. 143-149
    • Murillo, C.A.1    Rychahou, P.G.2    Evers, B.M.3
  • 42
    • 0028357885 scopus 로고
    • Quantitation of angiogenesis and antiangiogenesis in the chick embryo chorioallantoic membrane
    • Nguyen, M., Y. Shing, and J. Folkman. 1994. Quantitation of angiogenesis and antiangiogenesis in the chick embryo chorioallantoic membrane. Microvasc. Res. 47:31-40.
    • (1994) Microvasc. Res. , vol.47 , pp. 31-40
    • Nguyen, M.1    Shing, Y.2    Folkman, J.3
  • 43
    • 0027164524 scopus 로고
    • Rapid induction and isolation of focal adhesion complexes
    • Plopper, G., and D.E. Ingber. 1993. Rapid induction and isolation of focal adhesion complexes. Biochem. Biophys. Res. Commun. 193:571-578.
    • (1993) Biochem. Biophys. Res. Commun. , vol.193 , pp. 571-578
    • Plopper, G.1    Ingber, D.E.2
  • 44
    • 0035242371 scopus 로고    scopus 로고
    • VEGF-induced activation of phosphoinositide 3-kinase is dependent on focal adhesion kinase
    • Qi, J.H., and L. Claesson-Welsh. 2001. VEGF-induced activation of phosphoinositide 3-kinase is dependent on focal adhesion kinase. Exp. Cell Res. 263:173-182.
    • (2001) Exp. Cell Res. , vol.263 , pp. 173-182
    • Qi, J.H.1    Claesson-Welsh, L.2
  • 46
    • 0035010472 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase mediates integrin-dependent NF-κB and MAPK activation through separate signaling pathways
    • Reyes-Reyes, M., N. Mora, A. Zentella, and C. Rosales. 2001. Phosphatidylinositol 3-kinase mediates integrin-dependent NF-κB and MAPK activation through separate signaling pathways. J. Cell Sci. 114:1579-1589.
    • (2001) J. Cell Sci. , vol.114 , pp. 1579-1589
    • Reyes-Reyes, M.1    Mora, N.2    Zentella, A.3    Rosales, C.4
  • 47
    • 0034581635 scopus 로고    scopus 로고
    • The discovery of angiogenic factors: A historical review
    • Ribatti, D., A. Vacca, and M. Presta. 2000. The discovery of angiogenic factors: a historical review. Gen. Pharmacol. 35:227-231.
    • (2000) Gen. Pharmacol. , vol.35 , pp. 227-231
    • Ribatti, D.1    Vacca, A.2    Presta, M.3
  • 48
    • 1642385055 scopus 로고    scopus 로고
    • Low density lipoprotein receptor-related protein-1 promotes β1 integrin maturation and transport to the cell surface
    • Salicioni, A.M., A. Gaultier, C. Brownlee, M.K. Cheezum, and S.L. Gonias. 2004. Low density lipoprotein receptor-related protein-1 promotes β1 integrin maturation and transport to the cell surface. J. Biol. Chem. 279:10005-10012.
    • (2004) J. Biol. Chem. , vol.279 , pp. 10005-10012
    • Salicioni, A.M.1    Gaultier, A.2    Brownlee, C.3    Cheezum, M.K.4    Gonias, S.L.5
  • 49
    • 0031858633 scopus 로고    scopus 로고
    • Integrin-mediated signaling events in human endothelial cells
    • Short, S.M., G.A. Talbott, and R.L. Juliano. 1998. Integrin-mediated signaling events in human endothelial cells. Mol. Biol. Cell. 9:1969-1980.
    • (1998) Mol. Biol. Cell , vol.9 , pp. 1969-1980
    • Short, S.M.1    Talbott, G.A.2    Juliano, R.L.3
  • 50
    • 0032253109 scopus 로고    scopus 로고
    • The mechanics of vascular cell motility
    • Shuster, C.B., and I.M. Herman. 1998. The mechanics of vascular cell motility. Microcirculation. 5:239-257.
    • (1998) Microcirculation , vol.5 , pp. 239-257
    • Shuster, C.B.1    Herman, I.M.2
  • 51
    • 0037446897 scopus 로고    scopus 로고
    • Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by αvβ3 and α5β1 integrins
    • Sudhakar, A., H. Sugimoto, C. Yang, J. Lively, M. Zeisberg, and R. Kalluri. 2003. Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by αvβ3 and α5β1 integrins. Proc. Natl. Acad. Sci. USA. 100:4766-4771.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 4766-4771
    • Sudhakar, A.1    Sugimoto, H.2    Yang, C.3    Lively, J.4    Zeisberg, M.5    Kalluri, R.6
  • 52
    • 0026567377 scopus 로고
    • Human dermal microvascular endothelial but not human umbilical vein endothelial cells express CD36 in vivo and in vitro
    • Swerlick, R.A., K.H. Lee, T.M. Wick, and T.J. Lawley. 1992. Human dermal microvascular endothelial but not human umbilical vein endothelial cells express CD36 in vivo and in vitro. J. Immunol. 148:78-83.
    • (1992) J. Immunol. , vol.148 , pp. 78-83
    • Swerlick, R.A.1    Lee, K.H.2    Wick, T.M.3    Lawley, T.J.4
  • 53
    • 0037191047 scopus 로고    scopus 로고
    • Crystal structure of the TSP-1 type 1 repeats: A novel layered fold and its biological implication
    • Tan, K., M. Duquette, J.H. Liu, Y. Dong, R. Zhang, A. Joachimiak, J. Lawler, and J.H. Wang. 2002. Crystal structure of the TSP-1 type 1 repeats: a novel layered fold and its biological implication. J. Cell Biol. 159:373-382.
    • (2002) J. Cell Biol. , vol.159 , pp. 373-382
    • Tan, K.1    Duquette, M.2    Liu, J.H.3    Dong, Y.4    Zhang, R.5    Joachimiak, A.6    Lawler, J.7    Wang, J.H.8
  • 54
    • 0033538057 scopus 로고    scopus 로고
    • The role of phosphatidylinositol 3-kinase in vascular endothelial growth factor signaling
    • Thakker, G.D., D.P. Hajjar, W.A. Muller, and T.K. Rosengart. 1999. The role of phosphatidylinositol 3-kinase in vascular endothelial growth factor signaling. J. Biol. Chem. 274:10002-10007.
    • (1999) J. Biol. Chem. , vol.274 , pp. 10002-10007
    • Thakker, G.D.1    Hajjar, D.P.2    Muller, W.A.3    Rosengart, T.K.4
  • 55
    • 0027235410 scopus 로고
    • Transformation of NIH/3T3 to anchorage independence by H-ras is accompanied by loss of suppressor activity
    • Tolsma, S.S., J.D. Cohen, L.S. Ehrlich, and N.P. Bouck. 1993a. Transformation of NIH/3T3 to anchorage independence by H-ras is accompanied by loss of suppressor activity. Exp. Cell Res. 205:232-239.
    • (1993) Exp. Cell Res. , vol.205 , pp. 232-239
    • Tolsma, S.S.1    Cohen, J.D.2    Ehrlich, L.S.3    Bouck, N.P.4
  • 56
    • 0027290714 scopus 로고
    • Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity
    • Tolsma, S.S., O.V. Volpert, D.J. Good, W.A. Frazier, P.J. Polverini, and N. Bouck. 1993b. Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity. J. Cell Biol. 122:497-511.
    • (1993) J. Cell Biol. , vol.122 , pp. 497-511
    • Tolsma, S.S.1    Volpert, O.V.2    Good, D.J.3    Frazier, W.A.4    Polverini, P.J.5    Bouck, N.6
  • 57
    • 0034793669 scopus 로고    scopus 로고
    • Integrin activation is required for VEGF and FGF receptor protein presence on human microvascular endothelial cells
    • Tsou, R., and F.F. Isik. 2001. Integrin activation is required for VEGF and FGF receptor protein presence on human microvascular endothelial cells. Mol. Cell. Biochem. 224:81-89.
    • (2001) Mol. Cell. Biochem. , vol.224 , pp. 81-89
    • Tsou, R.1    Isik, F.F.2
  • 58
    • 0027449459 scopus 로고
    • Modulation of endothelial cell proliferation, adhesion, and motility by recombinant heparin-binding domain and synthetic peptides from the type I repeats of thrombospondin
    • Vogel, T., N.H. Guo, H.C. Krutzsch, D.A. Blake, J. Hartman, S. Mendelovitz, A. Panet, and D.D. Roberts. 1993. Modulation of endothelial cell proliferation, adhesion, and motility by recombinant heparin-binding domain and synthetic peptides from the type I repeats of thrombospondin. J. Cell. Biochem. 53:74-84.
    • (1993) J. Cell. Biochem. , vol.53 , pp. 74-84
    • Vogel, T.1    Guo, N.H.2    Krutzsch, H.C.3    Blake, D.A.4    Hartman, J.5    Mendelovitz, S.6    Panet, A.7    Roberts, D.D.8
  • 59
    • 0032568607 scopus 로고    scopus 로고
    • A human fibrosarcoma inhibits systemic angiogenesis and the growth of experimental metastases via thrombospondin-1
    • Volpert, O.V., J. Lawler, and N.P. Bouck. 1998. A human fibrosarcoma inhibits systemic angiogenesis and the growth of experimental metastases via thrombospondin-1. Proc. Natl. Acad. Sci. USA. 95:6343-6348.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 6343-6348
    • Volpert, O.V.1    Lawler, J.2    Bouck, N.P.3
  • 60
    • 0042972556 scopus 로고    scopus 로고
    • Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis
    • Watnick, R.S., Y.N. Cheng, A. Rangarajan, T.A. Ince, and R.A. Weinberg. 2003. Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis. Cancer Cell. 3:219-231.
    • (2003) Cancer Cell , vol.3 , pp. 219-231
    • Watnick, R.S.1    Cheng, Y.N.2    Rangarajan, A.3    Ince, T.A.4    Weinberg, R.A.5
  • 61
    • 0036790094 scopus 로고    scopus 로고
    • Endostatin associates with integrin α5β1 and caveolin-1, and activates Src via a tyrosyl phosphatase-dependent pathway in human endothelial cells
    • Wickstrom, S.A., K. Alitalo, and J. Keski-Oja. 2002. Endostatin associates with integrin α5β1 and caveolin-1, and activates Src via a tyrosyl phosphatase-dependent pathway in human endothelial cells. Cancer Res. 62:5580-5589.
    • (2002) Cancer Res. , vol.62 , pp. 5580-5589
    • Wickstrom, S.A.1    Alitalo, K.2    Keski-Oja, J.3
  • 62
    • 2442555007 scopus 로고    scopus 로고
    • An endostatin-derived peptide interacts with integrins and regulates actin cytoskeleton and migration of endothelial cells
    • Wickstrom, S.A., K. Alitalo, and J. Keski-Oja. 2004. An endostatin-derived peptide interacts with integrins and regulates actin cytoskeleton and migration of endothelial cells. J. Biol. Chem. 279:20178-20185.
    • (2004) J. Biol. Chem. , vol.279 , pp. 20178-20185
    • Wickstrom, S.A.1    Alitalo, K.2    Keski-Oja, J.3
  • 63
    • 0035868761 scopus 로고    scopus 로고
    • A novel function for the Tec family tyrosine kinase Itk in activation of β1 integrins by the T-cell receptor
    • Woods, M.L., W.J. Kivens, M.A. Adelsman, Y. Qiu, A. August, and Y. Shimizu. 2001. A novel function for the Tec family tyrosine kinase Itk in activation of β1 integrins by the T-cell receptor. EMBO J. 20:1232-1244.
    • (2001) EMBO J. , vol.20 , pp. 1232-1244
    • Woods, M.L.1    Kivens, W.J.2    Adelsman, M.A.3    Qiu, Y.4    August, A.5    Shimizu, Y.6
  • 64
    • 0029945524 scopus 로고    scopus 로고
    • Differential endothelial migration and proliferation to basic fibroblast growth factor and vascular endothelial growth factor
    • Yoshida, A., B. Anand-Apte, and B.R. Zetter. 1996. Differential endothelial migration and proliferation to basic fibroblast growth factor and vascular endothelial growth factor. Growth Factors. 13:57-64.
    • (1996) Growth Factors , vol.13 , pp. 57-64
    • Yoshida, A.1    Anand-Apte, B.2    Zetter, B.R.3
  • 65
    • 0035895711 scopus 로고    scopus 로고
    • Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family
    • Zachary, I., and G. Gliki. 2001. Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family. Cardiovasc. Res. 49:568-581.
    • (2001) Cardiovasc. Res. , vol.49 , pp. 568-581
    • Zachary, I.1    Gliki, G.2
  • 66
    • 0035920244 scopus 로고    scopus 로고
    • Vascular permeability factor (VPF)/vascular endothelial growth factor (VEGF) receptor-1 down-modulates VPF/VEGF receptor-2-mediated endothelial cell proliferation, but not migration, through phosphatidylinositol 3-kinase-dependent pathways
    • Zeng, H., H.F. Dvorak, and D. Mukhopadhyay. 2001. Vascular permeability factor (VPF)/vascular endothelial growth factor (VEGF) receptor-1 down-modulates VPF/VEGF receptor-2-mediated endothelial cell proliferation, but not migration, through phosphatidylinositol 3-kinase-dependent pathways. J. Biol. Chem. 276:26969-26979.
    • (2001) J. Biol. Chem. , vol.276 , pp. 26969-26979
    • Zeng, H.1    Dvorak, H.F.2    Mukhopadhyay, D.3
  • 67
    • 0019152389 scopus 로고
    • Migration of capillary endothelial cells is stimulated by tumour-derived factors
    • Zetter, B.R. 1980. Migration of capillary endothelial cells is stimulated by tumour-derived factors. Nature. 285:41-43.
    • (1980) Nature , vol.285 , pp. 41-43
    • Zetter, B.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.