메뉴 건너뛰기




Volumn 53, Issue 4 I, 2002, Pages 503-514

Nitric oxide as a unique signaling molecule in the vascular system: A historical overview

Author keywords

Cyclic GMP; Endothelium; Hypertension; Nitroglycerin; NO synthase; Platelet aggregation; Vasodilatation

Indexed keywords

CYCLIC GMP; GLYCERYL TRINITRATE; NEUROTRANSMITTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SPASMOLYTIC AGENT;

EID: 0036912721     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (573)

References (69)
  • 1
    • 0018311634 scopus 로고
    • Relaxation of bovine coronary artery and activation of coronary arterial guanylate cyclase by nitric oxide, nitroprusside and a carcinogenic nitrosoamine
    • Gruetter C A, Barry B K, McNamara D B, Gruetter D Y, Kadowitz P J, Ignarro L J. Relaxation of bovine coronary artery and activation of coronary arterial guanylate cyclase by nitric oxide, nitroprusside and a carcinogenic nitrosoamine. J Cyclic Nucleotide Protein Phosphor Res 1979; 5:211-224.
    • (1979) J Cyclic Nucleotide Protein Phosphor Res , vol.5 , pp. 211-224
    • Gruetter, C.A.1    Barry, B.K.2    McNamara, D.B.3    Gruetter, D.Y.4    Kadowitz, P.J.5    Ignarro, L.J.6
  • 2
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • Furchgott R F, Zawadzki J V. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980; 288:373-376.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 3
    • 0019430671 scopus 로고
    • Evidence for the inhibitory role of guanosine 3′,5′-monophosphate in ADP-induced human platelet aggregation in the presence of nitric oxide and related vasodilators
    • Mellion B T, Ignarro L J, Ohistein E H, Pontecorvo E G, Hyman A L, Kadowitz P J. Evidence for the inhibitory role of guanosine 3′,5′-monophosphate in ADP-induced human platelet aggregation in the presence of nitric oxide and related vasodilators. Blood 1981; 57:946-955.
    • (1981) Blood , vol.57 , pp. 946-955
    • Mellion, B.T.1    Ignarro, L.J.2    Ohistein, E.H.3    Pontecorvo, E.G.4    Hyman, A.L.5    Kadowitz, P.J.6
  • 4
    • 0020522496 scopus 로고
    • Inhibition of human platelet aggregation by S-nitrosothiols. Heme-dependent activation of soluble guanylate cyclase and stimulation of cyclic GMP accumulation
    • Mellion B T, Ignarro L J, Myers C B, Ohistein E H, Ballot B A, Hyman A L, Kadowitz P J. Inhibition of human platelet aggregation by S-nitrosothiols. Heme-dependent activation of soluble guanylate cyclase and stimulation of cyclic GMP accumulation. Mol Pharmacol 1983; 23:653-664.
    • (1983) Mol Pharmacol , vol.23 , pp. 653-664
    • Mellion, B.T.1    Ignarro, L.J.2    Myers, C.B.3    Ohistein, E.H.4    Ballot, B.A.5    Hyman, A.L.6    Kadowitz, P.J.7
  • 5
    • 0018936824 scopus 로고
    • Coronary arterial relaxation and guanylate cyclas activation by cigarette smoke, N′-nitrosonornicotine and nitric oxide
    • Gruetter C A, Barry B K, McNamara D B, Kadowitz P J, Ignarro L J. Coronary arterial relaxation and guanylate cyclas activation by cigarette smoke, N′-nitrosonornicotine and nitric oxide. J Pharmacol Exp Ther 1980a; 214:9-15.
    • (1980) J Pharmacol Exp Ther , vol.214 , pp. 9-15
    • Gruetter, C.A.1    Barry, B.K.2    McNamara, D.B.3    Kadowitz, P.J.4    Ignarro, L.J.5
  • 6
    • 0019179169 scopus 로고
    • Activation of coronary arterial guanylate cyclase by nitric oxide, nitroprusside, and nitrosoguanidine: Inhibition by calcium, lanthanum, and other cations, enhancement by thiols
    • Gruetter D Y, Gruetter C A, Barry B K, Baricos W H, Hyman A L, Kadowitz P J, Ignarro L J. Activation of coronary arterial guanylate cyclase by nitric oxide, nitroprusside, and nitrosoguanidine: Inhibition by calcium, lanthanum, and other cations, enhancement by thiols. Biochem Pharmacol 1980b; 29:2943-2950.
    • (1980) Biochem Pharmacol , vol.29 , pp. 2943-2950
    • Gruetter, D.Y.1    Gruetter, C.A.2    Barry, B.K.3    Baricos, W.H.4    Hyman, A.L.5    Kadowitz, P.J.6    Ignarro, L.J.7
  • 7
    • 0019443140 scopus 로고
    • Relationship between cyclic guanosine 3′,5′-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrite and nitric oxide: Effects of methylene blue and methemoglobin
    • Gruetter C A, Gruetter D Y, Lyon J E, Kadowitz P J, Ignarro L J. Relationship between cyclic guanosine 3′,5′-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrite and nitric oxide: Effects of methylene blue and methemoglobin. J Pharmacol Exp Ther 1981; 219:181-186.
    • (1981) J Pharmacol Exp Ther , vol.219 , pp. 181-186
    • Gruetter, C.A.1    Gruetter, D.Y.2    Lyon, J.E.3    Kadowitz, P.J.4    Ignarro, L.J.5
  • 8
    • 0019313372 scopus 로고
    • Requirement ofthiols for activation of coronary arterial guanylate cyclase by glyceryl trinitrate and sodium nitrite: Possible involvement of S-nitrosothiols
    • Ignarro L J, Gruetter C A. Requirement ofthiols for activation of coronary arterial guanylate cyclase by glyceryl trinitrate and sodium nitrite: Possible involvement of S-nitrosothiols. Biochim Biophys Acta 1980; 631:221-231.
    • (1980) Biochim Biophys Acta , vol.631 , pp. 221-231
    • Ignarro, L.J.1    Gruetter, C.A.2
  • 9
    • 0019322058 scopus 로고
    • Possible involvement of S-nitrosothiols in the activation of guanylate cyclase by nitroso compounds
    • Ignarro L J, Edwards J C, Gruetter D Y, Barry B K, Gruetter C A. Possible involvement of S-nitrosothiols in the activation of guanylate cyclase by nitroso compounds. FEBS Lett 1980a; 110:275-278.
    • (1980) FEBS Lett , vol.110 , pp. 275-278
    • Ignarro, L.J.1    Edwards, J.C.2    Gruetter, D.Y.3    Barry, B.K.4    Gruetter, C.A.5
  • 11
    • 0019388174 scopus 로고
    • Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: Evidence for the involvement of S-nitrosothiols as active intermediates
    • Ignarro L J, Lippton H, Edwards J C, Baricos W H, Hyman A L, Kadowitz P J, Gruetter C A. Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: Evidence for the involvement of S-nitrosothiols as active intermediates. J Pharmacol Exp Ther 1981; 218:739-749.
    • (1981) J Pharmacol Exp Ther , vol.218 , pp. 739-749
    • Ignarro, L.J.1    Lippton, H.2    Edwards, J.C.3    Baricos, W.H.4    Hyman, A.L.5    Kadowitz, P.J.6    Gruetter, C.A.7
  • 12
    • 0018388658 scopus 로고
    • Methemoglobin blockade of coronary arterial soluble guanylate cyclase activation by nitroso compounds and its reversal with dithiothreitol
    • Ohistein E H, Barry B K, Gruetter D Y, Ignarro L J. Methemoglobin blockade of coronary arterial soluble guanylate cyclase activation by nitroso compounds and its reversal with dithiothreitol. FEES Lett 1979; 102:316-320.
    • (1979) FEES Lett , vol.102 , pp. 316-320
    • Ohistein, E.H.1    Barry, B.K.2    Gruetter, D.Y.3    Ignarro, L.J.4
  • 13
    • 0017365359 scopus 로고
    • Stimulation of guanylate cyclase by sodium nitroprusside, nitroglycerin and nitric oxide in various tissue preparations and comparison to the effects of sodium azide and hydroxylamine
    • Katsuki S, Arnold W, Mittal C, Murad F. Stimulation of guanylate cyclase by sodium nitroprusside, nitroglycerin and nitric oxide in various tissue preparations and comparison to the effects of sodium azide and hydroxylamine. J Cyclic Nucleotide Res 1977; 3:23-35.
    • (1977) J Cyclic Nucleotide Res , vol.3 , pp. 23-35
    • Katsuki, S.1    Arnold, W.2    Mittal, C.3    Murad, F.4
  • 14
    • 0015595425 scopus 로고
    • Mechanism of tolerance development to organic nitrates
    • Needleman P, Johnson E M. Mechanism of tolerance development to organic nitrates. J Pharmacol Exp Ther 1973; 184:709-715.
    • (1973) J Pharmacol Exp Ther , vol.184 , pp. 709-715
    • Needleman, P.1    Johnson, E.M.2
  • 15
    • 0015713177 scopus 로고
    • Sulfhydryl requirement for relaxation of vascular smooth muscle
    • Needleman P, Jakschik B, Johnson E M, Sulfhydryl requirement for relaxation of vascular smooth muscle. J Pharmacol Exp Ther 1973; 187:324-331.
    • (1973) J Pharmacol Exp Ther , vol.187 , pp. 324-331
    • Needleman, P.1    Jakschik, B.2    Johnson, E.M.3
  • 16
    • 0019967216 scopus 로고
    • Vascular smooth muscle relaxation by nitro compounds: Reduced relaxation and cGMP elevation in tolerant vessels and reversal of tolerance by dithiothreitol
    • Axelsson K L, Anderson R G G, Wikberg J E S. Vascular smooth muscle relaxation by nitro compounds: Reduced relaxation and cGMP elevation in tolerant vessels and reversal of tolerance by dithiothreitol. Acta Pharmacol Toxicol 1982; 50:350-357.
    • (1982) Acta Pharmacol Toxicol , vol.50 , pp. 350-357
    • Axelsson, K.L.1    Anderson, R.G.G.2    Wikberg, J.E.S.3
  • 17
    • 0020614041 scopus 로고
    • Tolerance towards nitroglycerin, induced in vivo, is correlated to a reduced cGMP response and an alteration in cGMP turnover
    • Axelsson K L, Andersson R G. Tolerance towards nitroglycerin, induced in vivo, is correlated to a reduced cGMP response and an alteration in cGMP turnover. Eur J Pharmacol 1983; 88:71-79.
    • (1983) Eur J Pharmacol , vol.88 , pp. 71-79
    • Axelsson, K.L.1    Andersson, R.G.2
  • 18
    • 0021019453 scopus 로고
    • Potentiation of the cardiovascular effects of nitroglycerin by N-acetylcysteine
    • Horowitz J D, Antman E M, Lorell B H, Barry W H, Smith T W, Potentiation of the cardiovascular effects of nitroglycerin by N-acetylcysteine. Circulation 1983; 68:1247-1253.
    • (1983) Circulation , vol.68 , pp. 1247-1253
    • Horowitz, J.D.1    Antman, E.M.2    Lorell, B.H.3    Barry, W.H.4    Smith, T.W.5
  • 19
    • 0019990987 scopus 로고
    • Vascular tolerance to nitroglycerin and cyclic GMP generation in rat aortic smooth muscle
    • Keith R A, Burkman A M, Sokoloski T D, Fertel R. H. Vascular tolerance to nitroglycerin and cyclic GMP generation in rat aortic smooth muscle. J Pharmacol Exp Ther 1982; 221:525-531.
    • (1982) J Pharmacol Exp Ther , vol.221 , pp. 525-531
    • Keith, R.A.1    Burkman, A.M.2    Sokoloski, T.D.3    Fertel, R.H.4
  • 21
    • 0023240541 scopus 로고
    • Prevention and reversal of nitrate tolerance in patients with congestive heart failure
    • Packer M, Lee W H, Kessler P D, Gottlieb S S, Medina N, Yushak M. Prevention and reversal of nitrate tolerance in patients with congestive heart failure. N Engl J Med 1987; 317:799-804.
    • (1987) N Engl J Med , vol.317 , pp. 799-804
    • Packer, M.1    Lee, W.H.2    Kessler, P.D.3    Gottlieb, S.S.4    Medina, N.5    Yushak, M.6
  • 22
    • 0022574514 scopus 로고
    • Potentiation of nitroglycerin-induced coronary dilatation by N-acetylcysteine
    • Winniford M D, Kennedy P L, Wells P J, Hillis L D. Potentiation of nitroglycerin-induced coronary dilatation by N-acetylcysteine. Circulation 1986; 73:138-142.
    • (1986) Circulation , vol.73 , pp. 138-142
    • Winniford, M.D.1    Kennedy, P.L.2    Wells, P.J.3    Hillis, L.D.4
  • 23
    • 0017146235 scopus 로고
    • Calcium-independent modulation of cyclic GMP and activation of guanylate cyclase by nitrosamines
    • DeRubertis F R, Craven P A. Calcium-independent modulation of cyclic GMP and activation of guanylate cyclase by nitrosamines. Science 1976; 193:897-899.
    • (1976) Science , vol.193 , pp. 897-899
    • DeRubertis, F.R.1    Craven, P.A.2
  • 24
    • 0021894599 scopus 로고
    • The pharmacological and physiological role of cyclic GMP in vascular smooth muscle relaxation
    • Ignarro L J, Kadowitz P J. The pharmacological and physiological role of cyclic GMP in vascular smooth muscle relaxation. Annu Rev Pharmacol Toxicol 1985; 25:171-191.
    • (1985) Annu Rev Pharmacol Toxicol , vol.25 , pp. 171-191
    • Ignarro, L.J.1    Kadowitz, P.J.2
  • 25
    • 0019495457 scopus 로고
    • Purification of a soluble, sodium-nitroprussidestimulated guanylate cyclase from bovine lung
    • Gerzer R, Hofmann F, Schultz G. Purification of a soluble, sodium-nitroprussidestimulated guanylate cyclase from bovine lung. Eur J Biochem 1981; 116:479-486.
    • (1981) Eur J Biochem , vol.116 , pp. 479-486
    • Gerzer, R.1    Hofmann, F.2    Schultz, G.3
  • 26
    • 0020494044 scopus 로고
    • The separation of the heme and apoheme forms of soluble guanylate cyclase
    • Gerzer R, Radany E W, Garbers D L. The separation of the heme and apoheme forms of soluble guanylate cyclase. Biochem Biophys Res Commun 1982; 108:678-686.
    • (1982) Biochem Biophys Res Commun , vol.108 , pp. 678-686
    • Gerzer, R.1    Radany, E.W.2    Garbers, D.L.3
  • 27
    • 0006109789 scopus 로고
    • Activation of purified soluble guanylate cyclase by protoporphyrin IX
    • Ignarro L J, Wood K S, Wolin M S. Activation of purified soluble guanylate cyclase by protoporphyrin IX Proc Natl Acad Sci USA 1982a; 79:2870-2873.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 2870-2873
    • Ignarro, L.J.1    Wood, K.S.2    Wolin, M.S.3
  • 28
    • 0020485917 scopus 로고
    • Activation of purified guanylate cyclase by nitric oxide requires heme: Comparison of heme-deficient, hemereconstituted and heme-containing forms of soluble enzyme from bovine lung
    • Ignarro L J, Degnan J N, Baricos W H, Kadowitz P J, Wolin M S. Activation of purified guanylate cyclase by nitric oxide requires heme: Comparison of heme-deficient, hemereconstituted and heme-containing forms of soluble enzyme from bovine lung. Biochim Biophys Acta 1982b; 718:49-59.
    • (1982) Biochim Biophys Acta , vol.718 , pp. 49-59
    • Ignarro, L.J.1    Degnan, J.N.2    Baricos, W.H.3    Kadowitz, P.J.4    Wolin, M.S.5
  • 29
    • 0021323975 scopus 로고
    • Guanylate cyclase from bovine lung: Evidence that enzyme activation by phenylhydrazine is mediated by iron-phenyl hemoprotein complexes
    • Ignarro L J, Wood K S, Ballot B, Wolin M S. Guanylate cyclase from bovine lung: Evidence that enzyme activation by phenylhydrazine is mediated by iron-phenyl hemoprotein complexes. J Biol Chem 1984a; 259:5923-5931.
    • (1984) J Biol Chem , vol.259 , pp. 5923-5931
    • Ignarro, L.J.1    Wood, K.S.2    Ballot, B.3    Wolin, M.S.4
  • 30
    • 0021275463 scopus 로고
    • Regulation of soluble guanylate cyclase activity by porphyrins and metalloporphyrins
    • Ignarro L J, Ballot B, Wood K S. Regulation of soluble guanylate cyclase activity by porphyrins and metalloporphyrins. J Biol Chem 1984b; 259:6201-6207.
    • (1984) J Biol Chem , vol.259 , pp. 6201-6207
    • Ignarro, L.J.1    Ballot, B.2    Wood, K.S.3
  • 31
    • 0020198013 scopus 로고
    • Purification and properties of heme-deficient hepatic soluble guanylate cyclase: Effects of heme and other factors on enzyme activation by NO, NO-heme, and protoporphyrin IX
    • Ohistein E H, Wood K S, Ignarro L J. Purification and properties of heme-deficient hepatic soluble guanylate cyclase: Effects of heme and other factors on enzyme activation by NO, NO-heme, and protoporphyrin IX Arch Biochem Biophys 1982; 218:187-198.
    • (1982) Arch Biochem Biophys , vol.218 , pp. 187-198
    • Ohistein, E.H.1    Wood, K.S.2    Ignarro, L.J.3
  • 32
    • 0020491331 scopus 로고
    • Guanylate cyclase from bovine lung: A kinetic analysis of the regulation of the purified soluble enzyme by protoporphyrin IX, heme, and nitrosyl-heme
    • Wolin M S, Wood K S, Ignarro L J. Guanylate cyclase from bovine lung: A kinetic analysis of the regulation of the purified soluble enzyme by protoporphyrin IX, heme, and nitrosyl-heme. J Biol Chem 1982; 257:13312-13320.
    • (1982) J Biol Chem , vol.257 , pp. 13312-13320
    • Wolin, M.S.1    Wood, K.S.2    Ignarro, L.J.3
  • 33
    • 0021306536 scopus 로고
    • Regulation of purified soluble guanylate cyclase by porphyrins and metalloporphyrins: A unifying concept
    • Ignarro L J, Wood K S, Wolin M S. Regulation of purified soluble guanylate cyclase by porphyrins and metalloporphyrins: A unifying concept. Adv Cyclic Nucleotide Protein Phosphor Res 1984c; 17:267-274.
    • (1984) Adv Cyclic Nucleotide Protein Phosphor Res , vol.17 , pp. 267-274
    • Ignarro, L.J.1    Wood, K.S.2    Wolin, M.S.3
  • 35
    • 0030010784 scopus 로고    scopus 로고
    • Decomposition of S-nitrosoglutathione in the presence of copper ions and glutathione
    • Gorren A C, Schrammel A, Schmidt K, Mayer B, Decomposition of S-nitrosoglutathione in the presence of copper ions and glutathione. Arch Biochem Biophys 1996; 330:219-228.
    • (1996) Arch Biochem Biophys , vol.330 , pp. 219-228
    • Gorren, A.C.1    Schrammel, A.2    Schmidt, K.3    Mayer, B.4
  • 36
    • 0029836873 scopus 로고    scopus 로고
    • S-nitrosothiols and role of metal ions in decomposition to nitric oxide
    • Williams D L. S-nitrosothiols and role of metal ions in decomposition to nitric oxide. Methods Enzymol 1996; 268:299-308.
    • (1996) Methods Enzymol , vol.268 , pp. 299-308
    • Williams, D.L.1
  • 37
    • 0023505509 scopus 로고
    • Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
    • Ignarro L J, Buga G M, Wood K S, Byrns R E, Chaudhuri G. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci USA 1987a; 84:9265-9269.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 9265-9269
    • Ignarro, L.J.1    Buga, G.M.2    Wood, K.S.3    Byrns, R.E.4    Chaudhuri, G.5
  • 38
    • 0023518452 scopus 로고
    • Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical
    • Ignarro L J, Byrns R E, Buga G M, Wood K S. Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical. Circ Res 1987b; 61:866-879.
    • (1987) Circ Res , vol.61 , pp. 866-879
    • Ignarro, L.J.1    Byrns, R.E.2    Buga, G.M.3    Wood, K.S.4
  • 39
    • 0023198721 scopus 로고
    • Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
    • Palmer R M, Ferrige A G, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987; 327:524-526.
    • (1987) Nature , vol.327 , pp. 524-526
    • Palmer, R.M.1    Ferrige, A.G.2    Moncada, S.3
  • 40
    • 0022461711 scopus 로고
    • Activation of purified soluble guanylate cyclase by endothelium-derived relaxing factor from intrapulmonary artery and vein: Stimulation by acetylcholine, bradykinin and arachidonic acid
    • Ignarro L J, Harbison R G, Wood K S, Kadowitz P J. Activation of purified soluble guanylate cyclase by endothelium-derived relaxing factor from intrapulmonary artery and vein: Stimulation by acetylcholine, bradykinin and arachidonic acid. J Pharmacol Exp Ther 1986a; 237:893-900.
    • (1986) J Pharmacol Exp Ther , vol.237 , pp. 893-900
    • Ignarro, L.J.1    Harbison, R.G.2    Wood, K.S.3    Kadowitz, P.J.4
  • 41
    • 0001447798 scopus 로고
    • Pharmacological and biochemical properties of endothelium-derived relaxing factor (EDRF): Evidence that EDRF is closely related to nitric oxide (NO) radical
    • Ignarro L J, Wood K S, Byrns R E. Pharmacological and biochemical properties of endothelium-derived relaxing factor (EDRF): Evidence that EDRF is closely related to nitric oxide (NO) radical (abstract). Circulation 1986b; 74:11-287.
    • (1986) Circulation , vol.74 , pp. 11-287
    • Ignarro, L.J.1    Wood, K.S.2    Byrns, R.E.3
  • 42
    • 0022640297 scopus 로고
    • Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor
    • Gryglewski R J, Palmer R M J, Moncada S. Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature 1986; 320:454-456.
    • (1986) Nature , vol.320 , pp. 454-456
    • Gryglewski, R.J.1    Palmer, R.M.J.2    Moncada, S.3
  • 43
    • 0022456638 scopus 로고
    • Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor
    • Rubanyi G M, Vanhoutte P M. Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor. Am J Physiol 1986; 250:H822-H827.
    • (1986) Am J Physiol , vol.250
    • Rubanyi, G.M.1    Vanhoutte, P.M.2
  • 44
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
    • Beckman J S, Beckman T W, Chen J, Marshall P A, Freeman B A. Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 1990; 87:1620-1624.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1620-1624
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 45
    • 0022599662 scopus 로고
    • Endothelium-dependent inhibition of platelet aggregation
    • Azuma H, Ishikawa M, Sekizaki S. Endothelium-dependent inhibition of platelet aggregation. Br J Pharmacol 1986; 88:411-415.
    • (1986) Br J Pharmacol , vol.88 , pp. 411-415
    • Azuma, H.1    Ishikawa, M.2    Sekizaki, S.3
  • 46
    • 0024706628 scopus 로고
    • Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein
    • Ignarro L J. Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein. Circ Res 1989; 65:1-21.
    • (1989) Circ Res , vol.65 , pp. 1-21
    • Ignarro, L.J.1
  • 47
    • 0023145898 scopus 로고
    • Endothelium-dependent modulation of cGMP levels and intrinsic smooth muscle tone in isolated bovine intrapulmonary artery and vein
    • Ignarro L J, Byrns R E, Wood K S. Endothelium-dependent modulation of cGMP levels and intrinsic smooth muscle tone in isolated bovine intrapulmonary artery and vein. Circ Res 1987c; 60:82-92.
    • (1987) Circ Res , vol.60 , pp. 82-92
    • Ignarro, L.J.1    Byrns, R.E.2    Wood, K.S.3
  • 48
    • 0024475102 scopus 로고
    • NO-methylarginine, an inhibitor of endothelium-derived nitric oxide synthesis, is a potent pressor agent in the guinea pig: Does nitric oxide regulate blood pressure in vivo?
    • Aisaka K, Gross S S, Griffith O W, Levi R. NO-methylarginine, an inhibitor of endothelium-derived nitric oxide synthesis, is a potent pressor agent in the guinea pig: Does nitric oxide regulate blood pressure in vivo? Biochem Biophys Res Commun 1989; 160:881-886.
    • (1989) Biochem Biophys Res Commun , vol.160 , pp. 881-886
    • Aisaka, K.1    Gross, S.S.2    Griffith, O.W.3    Levi, R.4
  • 49
    • 0001599370 scopus 로고
    • Role of endothelium-derived nitric oxide in the regulation of blood pressure
    • Rees D D, Palmer R M, Moncada S. Role of endothelium-derived nitric oxide in the regulation of blood pressure. Proc Natl Acad Sci USA 1989; 86:3375-3378.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 3375-3378
    • Rees, D.D.1    Palmer, R.M.2    Moncada, S.3
  • 50
    • 0025812495 scopus 로고
    • Comparison of the inhibitory potencies of N(G)-methyl-, N(G)-nitro- and N(G)-amino-L-arginine on EDRF function in the rat: Evidence for continuous basal EDRF release
    • Vargas H M, Cuevas J M, Ignarro L J, Chaudhuri G. Comparison of the inhibitory potencies of N(G)-methyl-, N(G)-nitro- and N(G)-amino-L-arginine on EDRF function in the rat: Evidence for continuous basal EDRF release. J Pharmacol Exp Ther 1991; 257:1208-1215.
    • (1991) J Pharmacol Exp Ther , vol.257 , pp. 1208-1215
    • Vargas, H.M.1    Cuevas, J.M.2    Ignarro, L.J.3    Chaudhuri, G.4
  • 51
    • 84940621549 scopus 로고
    • Flow-dependent dilation in myograph-mounted resistance artery segments
    • Bevan J A, Joyce E H. Flow-dependent dilation in myograph-mounted resistance artery segments. Blood Vessels 1988; 25:101-104.
    • (1988) Blood Vessels , vol.25 , pp. 101-104
    • Bevan, J.A.1    Joyce, E.H.2
  • 52
    • 0026032652 scopus 로고
    • Shear stress-induced release of nitric oxide from endothelial cells grown on beads
    • Buga G M, Gold M E, Fukuto J M, Ignarro L J. Shear stress-induced release of nitric oxide from endothelial cells grown on beads. Hypertension 1991; 17:187-193.
    • (1991) Hypertension , vol.17 , pp. 187-193
    • Buga, G.M.1    Gold, M.E.2    Fukuto, J.M.3    Ignarro, L.J.4
  • 53
    • 0021360664 scopus 로고
    • Reactive dilation of large coronary arteries in conscious dogs
    • Hintze T H, Vatner S F. Reactive dilation of large coronary arteries in conscious dogs. Circ Res 1984; 54:50-57.
    • (1984) Circ Res , vol.54 , pp. 50-57
    • Hintze, T.H.1    Vatner, S.F.2
  • 54
    • 0021000747 scopus 로고
    • Two dilatory mechanisms of antianginal drugs on epicardial coronary arteries in vivo: Indirect, flow-dependent, endothelium-mediated dilation and direct smooth muscle relaxation
    • Holtz J, Giesler M, Bassenge E. Two dilatory mechanisms of antianginal drugs on epicardial coronary arteries in vivo: Indirect, flow-dependent, endothelium-mediated dilation and direct smooth muscle relaxation. Z Kardiol 1983; 72:98-106.
    • (1983) Z Kardiol , vol.72 , pp. 98-106
    • Holtz, J.1    Giesler, M.2    Bassenge, E.3
  • 55
    • 0021719788 scopus 로고
    • Flow-dependent, endothelium-mediated dilation of epicardial coronary arteries in conscious dogs: Effects of cyclooxygenase inhibition
    • Holtz J, Forstermann U, Poh, U, Giesler M, Bassenge E. Flow-dependent, endothelium-mediated dilation of epicardial coronary arteries in conscious dogs: Effects of cyclooxygenase inhibition. J Cardiovasc Pharmacol 1984; 6:1161-1169.
    • (1984) J Cardiovasc Pharmacol , vol.6 , pp. 1161-1169
    • Holtz, J.1    Forstermann, U.2    Poh, U.3    Giesler, M.4    Bassenge, E.5
  • 56
    • 84939685037 scopus 로고
    • Endothelium-dependent flow-induced dilation of canine femoral and saphenous arteries
    • Hull S S, Kaiser L, Jaffe M D, Sparks H V. Endothelium-dependent flow-induced dilation of canine femoral and saphenous arteries. Blood Vessels 1986; 23:183-198.
    • (1986) Blood Vessels , vol.23 , pp. 183-198
    • Hull, S.S.1    Kaiser, L.2    Jaffe, M.D.3    Sparks, H.V.4
  • 57
    • 0022545202 scopus 로고
    • Methylene blue and ETYA block flow-dependent dilation in canine femoral artery
    • Kaiser L, Hull S S, Jr., Sparks H V, Jr. Methylene blue and ETYA block flow-dependent dilation in canine femoral artery. Am J Physiol 1986; 250:H974-H981.
    • (1986) Am J Physiol , vol.250
    • Kaiser, L.1    Hull S.S., Jr.2    Sparks H.V., Jr.3
  • 58
    • 0022516979 scopus 로고
    • Flow-induced release of endothelium-derived relaxing factor
    • Rubanyi G M, Romero J C, Vanhoutte P M. Flow-induced release of endothelium-derived relaxing factor. Am J Physiol 1986; 250:H1145-H1149.
    • (1986) Am J Physiol , vol.250
    • Rubanyi, G.M.1    Romero, J.C.2    Vanhoutte, P.M.3
  • 59
    • 84940134338 scopus 로고
    • Effects of perfusion and endothelium on the reactivity of isolated resistance arteries
    • Tesfamariam B, Halpern W, Osol G. Effects of perfusion and endothelium on the reactivity of isolated resistance arteries. Blood Vessels 1985; 22:301-305.
    • (1985) Blood Vessels , vol.22 , pp. 301-305
    • Tesfamariam, B.1    Halpern, W.2    Osol, G.3
  • 60
    • 0029914567 scopus 로고    scopus 로고
    • Intracellular pH and tyrosine phosphorylation but not calcium determine shear stress-induced nitric oxide production in native endothelial cells
    • Ayajiki K, Kindermann M, Hecker M, Fleming I, Busse R. Intracellular pH and tyrosine phosphorylation but not calcium determine shear stress-induced nitric oxide production in native endothelial cells. Circ Res 1996; 78:750-758.
    • (1996) Circ Res , vol.78 , pp. 750-758
    • Ayajiki, K.1    Kindermann, M.2    Hecker, M.3    Fleming, I.4    Busse, R.5
  • 61
    • 0030990083 scopus 로고    scopus 로고
    • Calcium-dependent and calcium-independent activation of the endothelial NO synthase
    • Fleming I, Bauersachs J, Busse R. Calcium-dependent and calcium-independent activation of the endothelial NO synthase. J Vasc Res 1997; 34:165-174.
    • (1997) J Vasc Res , vol.34 , pp. 165-174
    • Fleming, I.1    Bauersachs, J.2    Busse, R.3
  • 62
    • 0027096817 scopus 로고
    • Constitutive nitric oxide synthase from cerebellum is reversibly inhibited by nitric oxide formed from L-arginine
    • Rogers N E, Ignarro L J. Constitutive nitric oxide synthase from cerebellum is reversibly inhibited by nitric oxide formed from L-arginine. Biochem Biophys Res Commun 1992; 189:242-249.
    • (1992) Biochem Biophys Res Commun , vol.189 , pp. 242-249
    • Rogers, N.E.1    Ignarro, L.J.2
  • 63
    • 0027436619 scopus 로고
    • Negative feedback regulation of endothelial cell function by nitric oxide
    • Buga G M, Griscavage J M, Rogers N E, Ignarro L J. Negative feedback regulation of endothelial cell function by nitric oxide. Circ Res 1993; 73:808-812.
    • (1993) Circ Res , vol.73 , pp. 808-812
    • Buga, G.M.1    Griscavage, J.M.2    Rogers, N.E.3    Ignarro, L.J.4
  • 64
    • 33750824305 scopus 로고    scopus 로고
    • Nitric oxide regulates endothelium-dependent vasodilator responses in rabbit hindquarters vascular bed in vivo
    • Cohen G A, Hobbs A J, Fitch R M, Zinner M J, Chaudhuri G, Ignarro L J. Nitric oxide regulates endothelium-dependent vasodilator responses in rabbit hindquarters vascular bed in vivo. Am J Physiol 1996; 271:H133-H139.
    • (1996) Am J Physiol , vol.271
    • Cohen, G.A.1    Hobbs, A.J.2    Fitch, R.M.3    Zinner, M.J.4    Chaudhuri, G.5    Ignarro, L.J.6
  • 65
    • 0029092658 scopus 로고
    • Neuronal nitric oxide synthase self-inactivates by forming a ferrous-nitrosyl complex during aerobic catalysis
    • Abu-Soud H M, Wang J, Rousseau D L, Fukuto J M, Ignarro L J, Stuehr D J. Neuronal nitric oxide synthase self-inactivates by forming a ferrous-nitrosyl complex during aerobic catalysis. J Biol Chem 1995; 270:22997-23006.
    • (1995) J Biol Chem , vol.270 , pp. 22997-23006
    • Abu-Soud, H.M.1    Wang, J.2    Rousseau, D.L.3    Fukuto, J.M.4    Ignarro, L.J.5    Stuehr, D.J.6
  • 66
    • 0025081992 scopus 로고
    • Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle
    • Ignarro L J, Bush P A, Buga G M, Wood K S, Fukuto J M, Rajfer J. Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle. Biochem Biophys Res Commun 1990; 170:843-850.
    • (1990) Biochem Biophys Res Commun , vol.170 , pp. 843-850
    • Ignarro, L.J.1    Bush, P.A.2    Buga, G.M.3    Wood, K.S.4    Fukuto, J.M.5    Rajfer, J.6
  • 67
    • 0026353632 scopus 로고
    • Nitric oxide as a mediator of relaxation of the corpus cavernosum in response to nonadrenergic, noncholinergic neurotransmission
    • Rajfer J, Aronson W J, Bush P A, Dorey F J, Ignarro L J. Nitric oxide as a mediator of relaxation of the corpus cavernosum in response to nonadrenergic, noncholinergic neurotransmission. N Engl J Med 1992; 326:90-94.
    • (1992) N Engl J Med , vol.326 , pp. 90-94
    • Rajfer, J.1    Aronson, W.J.2    Bush, P.A.3    Dorey, F.J.4    Ignarro, L.J.5
  • 69
    • 0026731333 scopus 로고
    • Biosynthesis of nitric oxide and citrulline from L-arginine by constitutive nitric oxide synthase present in rabbit corpus cavernosum
    • Bush P A, Gonzalez N E, Ignarro L J. Biosynthesis of nitric oxide and citrulline from L-arginine by constitutive nitric oxide synthase present in rabbit corpus cavernosum. Biochem Biophys Res Commun 1992; 186:308-314.
    • (1992) Biochem Biophys Res Commun , vol.186 , pp. 308-314
    • Bush, P.A.1    Gonzalez, N.E.2    Ignarro, L.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.