A novel CYR61-triggered 'CYR61-αvβ3 integrin loop' regulates breast cancer cell survival and chemosensitivity through activation of ERK1/ERK2 MAPK signaling pathway

Oncogene

Volumn 24, Issue 5, 2005, Pages 761-779

  Menendez, Javier A ^a,b   Vellon, Luciano ^a,b   Mehmi, Inderjit ^a   Teng, Poh K ^a   Griggs, David W ^c   Lupu, Ruth ^a,b,d  

^a Breast Cancer Translational Res Lab   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c PFIZER INC   (United States)

^d Evanston NW Hlthcare Res Institute ^*  (United States)

Author keywords

v 3; Breast cancer; CCN1; Chemotherapy; CYR61; ERK1 ERK2 MAPK; Heregulin; Paclitaxel; Taxol

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; ANTINEOPLASTIC AGENT; CYSTEINE RICH PROTEIN 61; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NEU DIFFERENTIATION FACTOR; PACLITAXEL; S 196; S 205; S 247; SC 56631; SC 68448; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

APOPTOSIS; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CANCER PREVENTION; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CHEMOSENSITIVITY; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYME INHIBITION; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INHIBITION KINETICS; NICK END LABELING; PHENOTYPIC VARIATION; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UPREGULATION;

ANGIOGENESIS INDUCING AGENTS; APOPTOSIS; BREAST NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMEDIATE-EARLY PROTEINS; INTEGRINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PACLITAXEL; RECEPTORS, VITRONECTIN; TUMOR SUPPRESSOR PROTEIN P53;

MINK CELL FOCUS-FORMING VIRUS;

EID: 13444291204     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208238     Document Type: Article

References (69)

1. Aoudjit F and Vuori K. (2001). Oncogene, 20, 4995-5004.
2. Atlas E, Mehmi I, Cardilla M, Tang CK and Lupu R. (2003). Mol. Cancer Res., 1, 165-175.
3. Babic AM, Chen CC and Lau LF. (1999). Mol. Cell. Biol., 19, 2958-2966.
4. Babic AM, Kireeva ML, Kolesnikova TV and Lau LF. (1998). Proc. Natl. Acad. Sci. USA, 95, 6355-6360.
5. Berenbaum MC. (1989). Pharmacol. Rev., 41, 93-141.
6. Blagosklonny MV and Fojo T. (1999). Int. J. Cancer, 83, 151-156.
7. Blagosklonny MV, Schulte TW, Nguyen P, Mimnaugh EG, Trepel J and Neckers L. (1995). Cancer Res., 55, 4623-4626.
8. Blagosklonny MV, Schulte T, Nguyen P, Trepel J and Neckers LM. (1996). Cancer Res., 56, 1851-1854.
9. Brigstock DR. (1999). Endocr. Rev., 20, 189-206.
10. Brigstock DR, Goldschmeding R, Katsube KI, Lam SC, Lau LF, Lyons K, Naus C, Perbal B, Riser B, Takigawa M and Yeger H. (2003). Mol. Pathol., 56, 127-128.
11. Chen CC, Chen N and Lau LF. (2001). J. Biol. Chem., 276, 10443-10452.
12. Chen N, Chen CC and Lau LF. (2000). J. Biol. Chem., 275, 24953-24961.
13. Cruet-Hennequart S, Maubant S, Luis J, Gauduchon P, Staedel C and Dedhar S. (2003). Oncogene, 22, 1688-1702.
14. Damiano JS, Cress AE, Hazlehurst LA, Shtil AA and Dalton WS. (1999). Blood, 93, 1658-1667.
15. Gasparini G, Brooks PC, Biganzoli E, Vermeulen PB, Bonoldi E, Dirix LY, Raneiri G, Miceli R and Cheresh DA. (1998). Clin. Cancer Res., 4, 2625-2634.
16. Giannakakau P, Robey R, Fojo T and Blagosklonny MV. (2001). Oncogene, 20, 3806-3813.
17. Gilmore AP, Metcalfe AD, Romer LH and Streuli CH. (2000). J. Cell Biol., 149, 431-446.
18. Griggs D, Shannon K, Settle S, Duffin T, Nickols M, Schroeter S, Nickols G and Westlin W. (2001). Proc. Am. Assoc. Cancer Res., 42, 263.
19. Grzeszkiewicz TM, Kirschling DJ, Chen N and Lau LF. (2001). J. Biol. Chem., 276, 21943-21950.
20. Harris LN, Yang L, Tang C, Yang D and Lupu R. (1998). Clin. Cancer Res., 4, 1005-1012.
21. Hortobagyi GN, Holmes FA, Ibrahim N, Champlin R and Buzdar AU. (1997). Semin. Oncol., 24, S30-S33.
22. Jedsadayanmata A, Chen CC, Kireeva ML, Lau LF and Lam SCT. (1999). J. Biol. Chem., 274, 24321-24327.
23. King WG, Mattaliano MD, Chan TO, Tsichlis PN and Brugge JS. (1997). Mol. Cell. Biol., 17, 4406-4418.
24. Kireeva ML, Lam SCT and Lau LF. (1998). J. Biol. Chem., 273, 3090-3096.
25. Lau LF and Lam SC-T. (1999). Exp. Cell Res., 248, 44-57.
26. Lee JW and Juliano RL. (2000). Mol. Biol. Cell, 11, 1973-1987.
27. Leu SJ, Lam SC and Lau LF. (2002). J. Biol. Chem., 277, 46248-46255.
28. Lin MT, Chang CC, Chen ST, Chang HL, Su JL, Chau YP and Kuo ML. (2004). J. Biol. Chem., 279, 24015-24023.
29. Lupu R, Cardillo M, Cho C, Harris L, Hijazi M, Perez C, Rosenberg K, Yang D and Tang C. (1996). Breast Cancer Res. Treat., 38, 57-66.
30. MacKeigan JP, Collins TS and Ting JP-Y. (2000). J. Biol. Chem., 275, 38953-38956.
31. MacKeigan JP, Taxman DJ, Hunter D, Earp III HS, Graves LM and Ting JP. (2002). Clin. Cancer Res., 8, 2091-2099.
32. McDaid HM and Horwitz SB. (2001). Mol. Pharmacol., 60, 290-301.
33. Menendez JA, Mehmi I, Griggs DW and Lupu R. (2003). Endocrine Rel. Cancer, 10, 141-152.
34. Meyer D, Nickols G, Pegg J and Westlin W. (2001). Proc. Am. Assoc. Cancer Res., 42, 825.
35. Meyer T, Marshall JF and Hart TR. (1998). Br. J. Cancer, 77, 530-536.
36. Novak A, Hsu SC, Leung-Hagesteijn C, Radeva G, Papkoff J, Montesano R, Roskelley C, Grosschedl R and Dedhar S. (1998). Proc. Natl. Acad. Sci. USA, 95, 4374-4379.
37. O'Kelly J, Xie D, Tong X-J, Lemp N, Miller and Koefller P. (2002). Proc. Am. Assoc. Cancer Res., 42, (abstract 5629).
38. Parness J and Horwitz SB. (1981). J. Cell Biol., 91, 479-487.
39. Perbal B. (2001). Mol. Pathol., 54, 103-104.
40. Perbal B. (2004). Lancet, 363, 62-64.
41. Perez EA. (1998). Oncologist, 3, 373-389.
42. Planque N and Perbal B. (2003). Cancer Cell Int., 3, 15.
43. Radeva G, Petrocelli T, Behrend E, Leung-Hagesteijn C, Filmus J, Slingerland J and Dedhar S. (1997). J. Biol. Chem., 272, 13937-13944.
44. Rasouli-Nia A, Liu D, Perdue S and Britten RA. (1998). Clin. Cancer Res., 4, 1111-1116.
45. Reinmuth N, Liu W, Ahmad SA, Fan F, Stoeltzing O, Parikh AA, Bucana CD, Gallick GE, Nickols MA, Westlin WF and Ellis LM. (2003). Cancer Res., 63, 2079-2087.
46. Roberts MS, Woods AJ, Shaw PE and Norman JC. (2003). J. Biol. Chem., 278, 1975-1985.
47. Rosen K, Rak J, Leung T, Dean NM, Kerbel RS and Filmus J. (2000). J. Cell Biol., 149, 447-456.
48. Sampath D, Winneker RC and Zhang Z. (2001). Endocrinology, 142, 2540-2548.
49. Schiff PB, Fant J and Horwitz SB. (1979). Nature, 277, 665-667.
50. Seidman R, Gitelman I, Sagi O, Horwitz SB and Wolfson M. (2001). Exp. Cell. Res., 268, 84-92.
51. Staebler A, Sommers C, Mueller SC, Byers S, Thompson EW and Lupu R. (1994). Breast Cancer Res. Treat., 31, 175-182.
52. Torres K and Horwitz SB. (1998). Cancer Res., 58, 3620-3626.
53. Tsai M-S, Bogart DF, Castaneda JM, Li P and Lupu R. (2002). Oncogene, 21, 8178-8185.
54. Tsai M-S, Hornby AE, Lakins J and Lupu R. (2000). Cancer Res., 60, 5603-5607.
55. Tsai MS, Shamon-Taylor LA, Mehmi I, Tang CK and Lupu R. (2003). Oncogene, 22, 761-768.
56. Vellon L, Menendez JA and Lupu R. (2004). Proc. Am. Assoc. Cancer Res., 45, (abstract LB-77, p.74).
57. Wiseman LR and Spencer CM. (1998). Drugs Aging, 12, 305-334.
58. Xie D, Miller CW, O'Kelly J, Nakachi K, Sakashita A, Said JW, Gorbein J and Koeffler HP. (2001a). J. Biol. Chem., 276, 14187-14194.
59. Xie D, Nakachi K, Wang H, Elashoff R and Koeffler P. (2001b). Cancer Res., 61, 8917-8923.
60. Xie D, Yin D, Tong X, O'Kelly J, Mori A, Miller C, Black K, Gui D, Said JW and Koeffler HP. (2004). Cancer Res., 64, 1987-1996.
61. Yang PG and Lau FL. (1991). Cell Growth Differ., 2, 351-357.
62. Yoganathan TN, Costello P, Chen X, Jabali M, Yan J, Leung D, Zhang Z, Yee A, Dedhar S and Sanghera J. (2000). Biochem. Pharmacol., 60, 1115-1159.
63. Yu C, Wang S, Dent P and Grant S. (2001). Mol. Pharmacol., 60, 143-154.
64. Yu D. (2001). Semin. Oncol., 28, 12-17.
65. Yu D and Hung MC. (2000). BioEssays, 22, 673-680.
66. Yu D, Jing T, Liu B, Yao J, Tan M, McDonnell TJ and Hung MC. (1998). Mol. Cell, 2, 581-591.
67. Yu D, Liu B, Tan M, Li J, Wang SS and Hung MC. (1996). Oncogene, 13, 1359-1365.
68. Zhang L, Bewick M and Lafrenie RM. (2002). Carcinogenesis, 23, 1251-1258.
69. Zimmermann S and Moelling K. (1999). Science, 286, 1741-1744.