메뉴 건너뛰기




Volumn 27, Issue 11, 2007, Pages 2302-2309

Osteopontin: A multifunctional molecule regulating chronic inflammation and vascular disease

Author keywords

Atherosclerosis; Inflammation; Osteopontin; Osteopontin proteolytic processing

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; CYTOKINE; HETERODIMER; INTEGRIN; INTEGRIN RECEPTOR; MATRIX METALLOPROTEINASE; OSTEOPONTIN; PROTEINASE; THROMBIN;

EID: 36048959129     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.107.144824     Document Type: Short Survey
Times cited : (567)

References (114)
  • 2
    • 0033731371 scopus 로고    scopus 로고
    • Osteopontin: A versatile regulator of inflammation and biomineralization
    • Giachelli CM, Steitz S. Osteopontin: a versatile regulator of inflammation and biomineralization. Matrix Biol. 2000;19:615-622.
    • (2000) Matrix Biol , vol.19 , pp. 615-622
    • Giachelli, C.M.1    Steitz, S.2
  • 3
    • 0029644944 scopus 로고
    • Expression of osteopontin in the head process late in gastrulation in the rat
    • Thayer JM, Giachelli CM, Mirkes PE, Schwartz SM. Expression of osteopontin in the head process late in gastrulation in the rat. J Exp Zool. 1995;272:240-244.
    • (1995) J Exp Zool , vol.272 , pp. 240-244
    • Thayer, J.M.1    Giachelli, C.M.2    Mirkes, P.E.3    Schwartz, S.M.4
  • 4
    • 0027931452 scopus 로고
    • Alterations in the expression of osteonectin, osteopontin and osteocalcin mRNAs during the development of skeletal tissues in vivo
    • Nakase T, Takaoka K, Hirakawa K, Hirota S, Takemura T, Onoue H, Takebayashi K, Kitamura Y, Nomura S. Alterations in the expression of osteonectin, osteopontin and osteocalcin mRNAs during the development of skeletal tissues in vivo. Bone Miner. 1994;26:109-122.
    • (1994) Bone Miner , vol.26 , pp. 109-122
    • Nakase, T.1    Takaoka, K.2    Hirakawa, K.3    Hirota, S.4    Takemura, T.5    Onoue, H.6    Takebayashi, K.7    Kitamura, Y.8    Nomura, S.9
  • 5
    • 17144434155 scopus 로고    scopus 로고
    • Expression of genes for non-collagenous proteins during embryonic bone formation
    • discussion 36-39
    • Nomura S, Wills AJ, Edwards DR, Heath JK, Hogan BL. Expression of genes for non-collagenous proteins during embryonic bone formation. Connect Tissue Res. 21:31-35, 1989;discussion 36-39.
    • Connect Tissue Res , vol.21 , Issue.31-35 , pp. 1989
    • Nomura, S.1    Wills, A.J.2    Edwards, D.R.3    Heath, J.K.4    Hogan, B.L.5
  • 7
    • 34247343353 scopus 로고    scopus 로고
    • Osteopontin, a protein with cytokine-like properties, is associated with inflammation in Crohn's disease
    • Agnholt J, Kelsen J, Schack L, Hvas CL, Dahlerup JF, Sorensen ES. Osteopontin, a protein with cytokine-like properties, is associated with inflammation in Crohn's disease. Scand J Immunol. 2007;65:453-460.
    • (2007) Scand J Immunol , vol.65 , pp. 453-460
    • Agnholt, J.1    Kelsen, J.2    Schack, L.3    Hvas, C.L.4    Dahlerup, J.F.5    Sorensen, E.S.6
  • 8
    • 7044264360 scopus 로고    scopus 로고
    • Role of osteopontin in adhesion, migration, cell survival and bone remodeling
    • Standal T, Borset M, Sundan A. Role of osteopontin in adhesion, migration, cell survival and bone remodeling. Exp Oncol. 2004;26:179-184.
    • (2004) Exp Oncol , vol.26 , pp. 179-184
    • Standal, T.1    Borset, M.2    Sundan, A.3
  • 9
    • 0035671826 scopus 로고    scopus 로고
    • Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer
    • Fedarko NS, Jain A, Karadag A, Van Eman MR, Fisher LW. Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer. Clin Cancer Res. 2001;7:4060-4066.
    • (2001) Clin Cancer Res , vol.7 , pp. 4060-4066
    • Fedarko, N.S.1    Jain, A.2    Karadag, A.3    Van Eman, M.R.4    Fisher, L.W.5
  • 12
    • 21244447455 scopus 로고    scopus 로고
    • Elevation of plasma osteopontin concentration is correlated with disease activity in patients with systemic lupus erythematosus
    • Wong CK, Lit LC, Tam LS, Li EK, Lam CW. Elevation of plasma osteopontin concentration is correlated with disease activity in patients with systemic lupus erythematosus. Rheumatology (Oxford). 2005;44:602-606.
    • (2005) Rheumatology (Oxford) , vol.44 , pp. 602-606
    • Wong, C.K.1    Lit, L.C.2    Tam, L.S.3    Li, E.K.4    Lam, C.W.5
  • 19
    • 0036688817 scopus 로고    scopus 로고
    • Osteopontin deficiency increases mineral content and mineral crystallinity in mouse bone
    • Boskey AL, Spevak L, Paschalis E, Doty SB, McKee MD. Osteopontin deficiency increases mineral content and mineral crystallinity in mouse bone. Calcif Tissue Int. 2002;71:145-154.
    • (2002) Calcif Tissue Int , vol.71 , pp. 145-154
    • Boskey, A.L.1    Spevak, L.2    Paschalis, E.3    Doty, S.B.4    McKee, M.D.5
  • 21
    • 0027249892 scopus 로고
    • Osteopontin-hydroxyapatite interactions in vitro: Inhibition of hydroxyapatite formation and growth in a gelatin-gel
    • Boskey AL, Maresca M, Ullrich W, Doty SB, Butler WT, Prince CW. Osteopontin-hydroxyapatite interactions in vitro: inhibition of hydroxyapatite formation and growth in a gelatin-gel. Bone Miner. 1993;22:147-159.
    • (1993) Bone Miner , vol.22 , pp. 147-159
    • Boskey, A.L.1    Maresca, M.2    Ullrich, W.3    Doty, S.B.4    Butler, W.T.5    Prince, C.W.6
  • 22
    • 0042855996 scopus 로고    scopus 로고
    • The integrin alpha(v)beta(3) and CD44 regulate the actions of osteopontin on osteoclast motility
    • Chellaiah MA, Hruska KA. The integrin alpha(v)beta(3) and CD44 regulate the actions of osteopontin on osteoclast motility. Calcif Tissue Int. 2003;72:197-205.
    • (2003) Calcif Tissue Int , vol.72 , pp. 197-205
    • Chellaiah, M.A.1    Hruska, K.A.2
  • 24
    • 0031959536 scopus 로고    scopus 로고
    • Control of calcium oxalate crystal structure and cell adherence by urinary macromolecules
    • Wesson JA, Worcester EM, Wiessner JH, Mandel NS, Kleinman JG. Control of calcium oxalate crystal structure and cell adherence by urinary macromolecules. Kidney Int. 1998;53:952-957.
    • (1998) Kidney Int , vol.53 , pp. 952-957
    • Wesson, J.A.1    Worcester, E.M.2    Wiessner, J.H.3    Mandel, N.S.4    Kleinman, J.G.5
  • 25
    • 0027367239 scopus 로고
    • Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques
    • Giachelli CM, Bae N, Almeida M, Denhardt DT, Alpers CE, Schwartz SM. Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques. J Clin Invest. 1993;92:1686-1696.
    • (1993) J Clin Invest , vol.92 , pp. 1686-1696
    • Giachelli, C.M.1    Bae, N.2    Almeida, M.3    Denhardt, D.T.4    Alpers, C.E.5    Schwartz, S.M.6
  • 26
    • 0037152187 scopus 로고    scopus 로고
    • Inactivation of the osteopontin gene enhances vascular calcification of matrix Gla protein-deficient mice: Evidence for osteopontin as an inducible inhibitor of vascular calcification in vivo
    • Speer MY, McKee MD, Guldberg RE, Liaw L, Yang HY, Tung E, Karsenty G, Giachelli CM. Inactivation of the osteopontin gene enhances vascular calcification of matrix Gla protein-deficient mice: evidence for osteopontin as an inducible inhibitor of vascular calcification in vivo. J Exp Med. 2002;196:1047-1055.
    • (2002) J Exp Med , vol.196 , pp. 1047-1055
    • Speer, M.Y.1    McKee, M.D.2    Guldberg, R.E.3    Liaw, L.4    Yang, H.Y.5    Tung, E.6    Karsenty, G.7    Giachelli, C.M.8
  • 27
    • 0035824898 scopus 로고    scopus 로고
    • Smooth muscle cell phenotypic transition associated with calcification: Upregulation of Cbfa1 and downregulation of smooth muscle lineage markers
    • Steitz SA, Speer MY, Curinga G, Yang HY, Haynes P, Aebersold R, Schinke T, Karsenty G, Giachelli CM. Smooth muscle cell phenotypic transition associated with calcification: upregulation of Cbfa1 and downregulation of smooth muscle lineage markers. Circ Res. 2001;89:1147-1154.
    • (2001) Circ Res , vol.89 , pp. 1147-1154
    • Steitz, S.A.1    Speer, M.Y.2    Curinga, G.3    Yang, H.Y.4    Haynes, P.5    Aebersold, R.6    Schinke, T.7    Karsenty, G.8    Giachelli, C.M.9
  • 28
    • 0033623454 scopus 로고    scopus 로고
    • Osteopontin (Eta-1) in cell-mediated immunity: Teaching an old dog new tricks
    • O'Regan AW, Nau GJ, Chupp GL, Berman JS. Osteopontin (Eta-1) in cell-mediated immunity: teaching an old dog new tricks. Immunol Today. 2000;21:475-478.
    • (2000) Immunol Today , vol.21 , pp. 475-478
    • O'Regan, A.W.1    Nau, G.J.2    Chupp, G.L.3    Berman, J.S.4
  • 29
    • 0028118893 scopus 로고
    • Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro
    • Liaw L, Almeida M, Hart CE, Schwartz SM, Giachelli CM. Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro. Circ Res. 1994;74:214-224.
    • (1994) Circ Res , vol.74 , pp. 214-224
    • Liaw, L.1    Almeida, M.2    Hart, C.E.3    Schwartz, S.M.4    Giachelli, C.M.5
  • 30
    • 0028982713 scopus 로고
    • Osteopontin and beta 3 integrin are coordinately expressed in regenerating endothelium in vivo and stimulate Arg-Gly-Asp-dependent endothelial migration in vitro
    • Liaw L, Lindner V, Schwartz SM, Chambers AF, Giachelli CM. Osteopontin and beta 3 integrin are coordinately expressed in regenerating endothelium in vivo and stimulate Arg-Gly-Asp-dependent endothelial migration in vitro. Circ Res. 1995;77:665-672.
    • (1995) Circ Res , vol.77 , pp. 665-672
    • Liaw, L.1    Lindner, V.2    Schwartz, S.M.3    Chambers, A.F.4    Giachelli, C.M.5
  • 31
    • 0028855585 scopus 로고
    • The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. Role of alpha v beta 3 in smooth muscle cell migration to osteopontin in vitro
    • Liaw L, Skinner MP, Raines EW, Ross R, Cheresh DA, Schwartz SM, Giachelli CM. The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. Role of alpha v beta 3 in smooth muscle cell migration to osteopontin in vitro. J Clin Invest. 1995;95:713-724.
    • (1995) J Clin Invest , vol.95 , pp. 713-724
    • Liaw, L.1    Skinner, M.P.2    Raines, E.W.3    Ross, R.4    Cheresh, D.A.5    Schwartz, S.M.6    Giachelli, C.M.7
  • 33
    • 0029957772 scopus 로고    scopus 로고
    • Autocrine secretion of osteopontin by vascular smooth muscle cells regulates their adhesion to collagen gels
    • Weintraub AS, Giachelli CM, Krauss RS, Almeida M, Taubman MB. Autocrine secretion of osteopontin by vascular smooth muscle cells regulates their adhesion to collagen gels. Am J Pathol. 1996;149:259-272.
    • (1996) Am J Pathol , vol.149 , pp. 259-272
    • Weintraub, A.S.1    Giachelli, C.M.2    Krauss, R.S.3    Almeida, M.4    Taubman, M.B.5
  • 34
    • 33750579753 scopus 로고    scopus 로고
    • Osteopontin regulates renal apoptosis and interstitial fibrosis in neonatal chronic unilateral ureteral obstruction
    • Yoo KH, Thornhill BA, Forbes MS, Coleman CM, Marcinko ES, Liaw L, Chevalier RL. Osteopontin regulates renal apoptosis and interstitial fibrosis in neonatal chronic unilateral ureteral obstruction. Kidney Int. 2006;70:1735-1741.
    • (2006) Kidney Int , vol.70 , pp. 1735-1741
    • Yoo, K.H.1    Thornhill, B.A.2    Forbes, M.S.3    Coleman, C.M.4    Marcinko, E.S.5    Liaw, L.6    Chevalier, R.L.7
  • 35
    • 0031711338 scopus 로고    scopus 로고
    • Upregulation of osteopontin expression in renal cortex of streptozotocininduced diabetic rats is mediated by bradykinin
    • Fischer JW, Tschope C, Reinecke A, Giachelli CM, Unger T. Upregulation of osteopontin expression in renal cortex of streptozotocininduced diabetic rats is mediated by bradykinin. Diabetes. 1998;47:1512-1518.
    • (1998) Diabetes , vol.47 , pp. 1512-1518
    • Fischer, J.W.1    Tschope, C.2    Reinecke, A.3    Giachelli, C.M.4    Unger, T.5
  • 38
  • 39
    • 36749002101 scopus 로고    scopus 로고
    • Thomas SE, Lombardi D, Giachelli C, Bohle A, Johnson RJ. Osteopontin expression, tubulointerstitial disease, and essential hypertension
    • Thomas SE, Lombardi D, Giachelli C, Bohle A, Johnson RJ. Osteopontin expression, tubulointerstitial disease, and essential hypertension.
  • 40
    • 0030926461 scopus 로고    scopus 로고
    • Osteopontin and p53 expression are associated with tumor progression in a case of synchronous, bilateral, invasive mammary carcinomas
    • Tuck AB, O'Malley FP, Singhal H, Tonkin KS, Harris JF, Bautista D, Chambers AF. Osteopontin and p53 expression are associated with tumor progression in a case of synchronous, bilateral, invasive mammary carcinomas. Arch Pathol Lab Med. 1997;121:578-584.
    • (1997) Arch Pathol Lab Med , vol.121 , pp. 578-584
    • Tuck, A.B.1    O'Malley, F.P.2    Singhal, H.3    Tonkin, K.S.4    Harris, J.F.5    Bautista, D.6    Chambers, A.F.7
  • 41
    • 0028148368 scopus 로고
    • Osteopontin is synthesized by macrophage, smooth muscle, and endothelial cells in primary and restenotic human coronary atherosclerotic plaques
    • O'Brien ER, Garvin MR, Stewart DK, Hinohara T, Simpson JB, Schwartz SM, Giachelli CM. Osteopontin is synthesized by macrophage, smooth muscle, and endothelial cells in primary and restenotic human coronary atherosclerotic plaques. Arterioscler Thromb. 1994;14:1648-1656.
    • (1994) Arterioscler Thromb , vol.14 , pp. 1648-1656
    • O'Brien, E.R.1    Garvin, M.R.2    Stewart, D.K.3    Hinohara, T.4    Simpson, J.B.5    Schwartz, S.M.6    Giachelli, C.M.7
  • 44
    • 0028152707 scopus 로고
    • Macrophages express osteopontin during repair of myocardial necrosis
    • Murry CE, Giachelli CM, Schwartz SM, Vracko R. Macrophages express osteopontin during repair of myocardial necrosis. Am J Pathol. 1994;145:1450-1462.
    • (1994) Am J Pathol , vol.145 , pp. 1450-1462
    • Murry, C.E.1    Giachelli, C.M.2    Schwartz, S.M.3    Vracko, R.4
  • 45
    • 0031904534 scopus 로고
    • Osteopontin and its integrin receptor alpha(v) beta3 are upregulated during formation of the glial scar after focal stroke
    • discussion
    • Ellison JA, Velier JJ, Spera P, Jonak ZL, Wang X, Barone FC, Feuerstein GZ. Osteopontin and its integrin receptor alpha(v) beta3 are upregulated during formation of the glial scar after focal stroke. Stroke. 1998;29:1698-1706; discussion 1707.
    • (1707) Stroke. 1998 , vol.29 , pp. 1698-1706
    • Ellison, J.A.1    Velier, J.J.2    Spera, P.3    Jonak, Z.L.4    Wang, X.5    Barone, F.C.6    Feuerstein, G.Z.7
  • 46
    • 0036499086 scopus 로고    scopus 로고
    • Jansson M, Panoutsakopoulou V, Baker J, Klein L, Cantor H. Cutting edge: Attenuated experimental autoimmune encephalomyelitis in eta-1/osteopontin- deficient mice. J Immunol. 2002;168:2096-2099.
    • Jansson M, Panoutsakopoulou V, Baker J, Klein L, Cantor H. Cutting edge: Attenuated experimental autoimmune encephalomyelitis in eta-1/osteopontin- deficient mice. J Immunol. 2002;168:2096-2099.
  • 47
    • 0036229093 scopus 로고    scopus 로고
    • Expression of osteopontin at sites of bone erosion in a murine experimental arthritis model of collagen-induced arthritis: Possible involvement of osteopontin in bone destruction in arthritis
    • Ohshima S, Kobayashi H, Yamaguchi N, Nishioka K, Umeshita-Sasai M, Mima T, Nomura S, Kon S, Inobe M, Uede T, Saeki Y. Expression of osteopontin at sites of bone erosion in a murine experimental arthritis model of collagen-induced arthritis: possible involvement of osteopontin in bone destruction in arthritis. Arthritis Rheum. 2002;46:1094-1101.
    • (2002) Arthritis Rheum , vol.46 , pp. 1094-1101
    • Ohshima, S.1    Kobayashi, H.2    Yamaguchi, N.3    Nishioka, K.4    Umeshita-Sasai, M.5    Mima, T.6    Nomura, S.7    Kon, S.8    Inobe, M.9    Uede, T.10    Saeki, Y.11
  • 48
    • 0042164569 scopus 로고    scopus 로고
    • Modification of elastin by pentosidine is associated with the calcification of aortic media in patients with end-stage renal disease
    • Sakata N, Noma A, Yamamoto Y, Okamoto K, Meng J, Takebayashi S, Nagai R, Horiuchi S. Modification of elastin by pentosidine is associated with the calcification of aortic media in patients with end-stage renal disease. Nephrol Dial Transplant. 2003;18:1601-1609.
    • (2003) Nephrol Dial Transplant , vol.18 , pp. 1601-1609
    • Sakata, N.1    Noma, A.2    Yamamoto, Y.3    Okamoto, K.4    Meng, J.5    Takebayashi, S.6    Nagai, R.7    Horiuchi, S.8
  • 49
    • 0030799667 scopus 로고    scopus 로고
    • Osteopontin is strongly expressed by histiocytes in granulomas of diverse etiology
    • Carlson I, Tognazzi K, Manseau EJ, Dvorak HF, Brown LF. Osteopontin is strongly expressed by histiocytes in granulomas of diverse etiology. Lab Invest. 1997;77:103-108.
    • (1997) Lab Invest , vol.77 , pp. 103-108
    • Carlson, I.1    Tognazzi, K.2    Manseau, E.J.3    Dvorak, H.F.4    Brown, L.F.5
  • 51
    • 0032770008 scopus 로고    scopus 로고
    • Attenuated host resistance against Mycobacterium bovis BCG infection in mice lacking osteopontin
    • Nau GJ, Liaw L, Chupp GL, Berman JS, Hogan BL, Young RA. Attenuated host resistance against Mycobacterium bovis BCG infection in mice lacking osteopontin. Infect Immun. 1999;67:4223-4230.
    • (1999) Infect Immun , vol.67 , pp. 4223-4230
    • Nau, G.J.1    Liaw, L.2    Chupp, G.L.3    Berman, J.S.4    Hogan, B.L.5    Young, R.A.6
  • 52
    • 0028981367 scopus 로고
    • The human integrin alpha 8 beta 1 functions as a receptor for tenascin, fibronectin, and vitronectin
    • Schnapp LM, Hatch N, Ramos DM, Klimanskaya IV, Sheppard D, Pytela R. The human integrin alpha 8 beta 1 functions as a receptor for tenascin, fibronectin, and vitronectin. J Biol Chem. 1995;270:23196-23202.
    • (1995) J Biol Chem , vol.270 , pp. 23196-23202
    • Schnapp, L.M.1    Hatch, N.2    Ramos, D.M.3    Klimanskaya, I.V.4    Sheppard, D.5    Pytela, R.6
  • 53
    • 0029946457 scopus 로고    scopus 로고
    • Osteopontin N-terminal domain contains a cryptic adhesive sequence recognized by alpha9beta1 integrin
    • Smith LL, Cheung HK, Ling LE, Chen J, Sheppard D, Pytela R, Giachelli CM. Osteopontin N-terminal domain contains a cryptic adhesive sequence recognized by alpha9beta1 integrin. J Biol Chem. 1996;271:28485-28491.
    • (1996) J Biol Chem , vol.271 , pp. 28485-28491
    • Smith, L.L.1    Cheung, H.K.2    Ling, L.E.3    Chen, J.4    Sheppard, D.5    Pytela, R.6    Giachelli, C.M.7
  • 55
    • 0035918153 scopus 로고    scopus 로고
    • Identification of dual alpha 4beta1 integrin binding sites within a 38 amino acid domain in the N-terminal thrombin fragment of human osteopontin
    • Bayless KJ, Davis GE. Identification of dual alpha 4beta1 integrin binding sites within a 38 amino acid domain in the N-terminal thrombin fragment of human osteopontin. J Biol Chem. 2001;276:13483-13489.
    • (2001) J Biol Chem , vol.276 , pp. 13483-13489
    • Bayless, K.J.1    Davis, G.E.2
  • 57
    • 0035839024 scopus 로고    scopus 로고
    • Structural elements of the osteopontin SVVYGLR motif important for the interaction with alpha(4) integrins
    • Green PM, Ludbrook SB, Miller DD, Horgan CM, Barry ST. Structural elements of the osteopontin SVVYGLR motif important for the interaction with alpha(4) integrins. FEBS Lett. 2001;503:75-79.
    • (2001) FEBS Lett , vol.503 , pp. 75-79
    • Green, P.M.1    Ludbrook, S.B.2    Miller, D.D.3    Horgan, C.M.4    Barry, S.T.5
  • 58
    • 0031845051 scopus 로고    scopus 로고
    • Structural requirements for alpha 9 beta 1-mediated adhesion and migration to thrombin-cleaved osteopontin
    • Smith LL, Giachelli CM. Structural requirements for alpha 9 beta 1-mediated adhesion and migration to thrombin-cleaved osteopontin. Exp Cell Res. 1998;242:351-360.
    • (1998) Exp Cell Res , vol.242 , pp. 351-360
    • Smith, L.L.1    Giachelli, C.M.2
  • 59
    • 0035958935 scopus 로고    scopus 로고
    • Osteopontin, a novel substrate for matrix metalloproteinase-3 (stromelysin-1) and matrix metalloproteinase-7 (matrilysin)
    • Agnihotri R, Crawford HC, Haro H, Matrisian LM, Havrda MC, Liaw L. Osteopontin, a novel substrate for matrix metalloproteinase-3 (stromelysin-1) and matrix metalloproteinase-7 (matrilysin). J Biol Chem. 2001;276:28261-28267.
    • (2001) J Biol Chem , vol.276 , pp. 28261-28267
    • Agnihotri, R.1    Crawford, H.C.2    Haro, H.3    Matrisian, L.M.4    Havrda, M.C.5    Liaw, L.6
  • 61
    • 28844482875 scopus 로고    scopus 로고
    • Distinct structural requirements for binding of the integrins alphavbeta6, alphavbeta3, alphavbeta5, alpha5beta1 and alpha9beta1 to osteopontin
    • Yokosaki Y, Tanaka K, Higashikawa F, Yamashita K, Eboshida A. Distinct structural requirements for binding of the integrins alphavbeta6, alphavbeta3, alphavbeta5, alpha5beta1 and alpha9beta1 to osteopontin. Matrix Biol. 2005;24:418-427.
    • (2005) Matrix Biol , vol.24 , pp. 418-427
    • Yokosaki, Y.1    Tanaka, K.2    Higashikawa, F.3    Yamashita, K.4    Eboshida, A.5
  • 62
    • 0028228866 scopus 로고
    • Adhesive properties of osteopontin: Regulation by a naturally occurring thrombin-cleavage in close proximity to the GRGDS cell-binding domain
    • Senger DR, Perruzzi CA, Papadopoulos Sergiou A, Van de Water L. Adhesive properties of osteopontin: regulation by a naturally occurring thrombin-cleavage in close proximity to the GRGDS cell-binding domain. Mol Biol Cell. 1994;5:565-574.
    • (1994) Mol Biol Cell , vol.5 , pp. 565-574
    • Senger, D.R.1    Perruzzi, C.A.2    Papadopoulos Sergiou, A.3    Van de Water, L.4
  • 63
    • 9644281627 scopus 로고    scopus 로고
    • Expression and characterization of recombinant osteopontin peptides representing matrix metalloproteinase proteolytic fragments
    • Gao YA, Agnihotri R, Vary CP, Liaw L. Expression and characterization of recombinant osteopontin peptides representing matrix metalloproteinase proteolytic fragments. Matrix Biol. 2004;23:457-466.
    • (2004) Matrix Biol , vol.23 , pp. 457-466
    • Gao, Y.A.1    Agnihotri, R.2    Vary, C.P.3    Liaw, L.4
  • 64
    • 0035733907 scopus 로고    scopus 로고
    • Distinct roles of osteopontin fragments in the development of the pulmonary involvement in sarcoidosis
    • Maeda K, Takahashi K, Takahashi F, Tamura N, Maeda M, Kon S, Uede T, Fukuchi Y. Distinct roles of osteopontin fragments in the development of the pulmonary involvement in sarcoidosis. Lung. 2001;179:279-291.
    • (2001) Lung , vol.179 , pp. 279-291
    • Maeda, K.1    Takahashi, K.2    Takahashi, F.3    Tamura, N.4    Maeda, M.5    Kon, S.6    Uede, T.7    Fukuchi, Y.8
  • 66
    • 0030064334 scopus 로고    scopus 로고
    • Receptor-ligand interaction between CD44 and osteopontin (Eta-1)
    • Weber GF, Ashkar S, Glimcher MJ, Cantor H. Receptor-ligand interaction between CD44 and osteopontin (Eta-1). Science. 1996;271:509-512.
    • (1996) Science , vol.271 , pp. 509-512
    • Weber, G.F.1    Ashkar, S.2    Glimcher, M.J.3    Cantor, H.4
  • 67
    • 0030941056 scopus 로고    scopus 로고
    • Interaction between CD44 and osteopontin as a potential basis for metastasis formation
    • Weber GF, Ashkar S, Cantor H. Interaction between CD44 and osteopontin as a potential basis for metastasis formation. Proc Assoc Am Physicians. 1997;109:1-9.
    • (1997) Proc Assoc Am Physicians , vol.109 , pp. 1-9
    • Weber, G.F.1    Ashkar, S.2    Cantor, H.3
  • 68
    • 0042707709 scopus 로고    scopus 로고
    • Rho-dependent Rho kinase activation increases CD44 surface expression and bone resorption in osteoclasts
    • Chellaiah MA, Biswas RS, Rittling SR, Denhardt DT, Hruska KA. Rho-dependent Rho kinase activation increases CD44 surface expression and bone resorption in osteoclasts. J Biol Chem. 2003;278:29086-29097.
    • (2003) J Biol Chem , vol.278 , pp. 29086-29097
    • Chellaiah, M.A.1    Biswas, R.S.2    Rittling, S.R.3    Denhardt, D.T.4    Hruska, K.A.5
  • 75
    • 0030983922 scopus 로고    scopus 로고
    • Transglutaminase-catalyzed cross-linking of osteopontin is inhibited by osteocalcin
    • Kaartinen MT, Pirhonen A, Linnala Kankkunen A, Maenpaa PH. Transglutaminase-catalyzed cross-linking of osteopontin is inhibited by osteocalcin. J Biol Chem. 1997;272:22736-22741.
    • (1997) J Biol Chem , vol.272 , pp. 22736-22741
    • Kaartinen, M.T.1    Pirhonen, A.2    Linnala Kankkunen, A.3    Maenpaa, P.H.4
  • 76
    • 3042722398 scopus 로고    scopus 로고
    • Enhancing the biological activity of immobilized osteopontin using a type-1 collagen affinity coating
    • Martin SM, Schwartz JL, Giachelli CM, Ratner BD. Enhancing the biological activity of immobilized osteopontin using a type-1 collagen affinity coating. J Biomed Mater Res A. 2004;70:10-19.
    • (2004) J Biomed Mater Res A , vol.70 , pp. 10-19
    • Martin, S.M.1    Schwartz, J.L.2    Giachelli, C.M.3    Ratner, B.D.4
  • 77
    • 0032533862 scopus 로고    scopus 로고
    • Distinct roles of osteopontin in host defense activity and tumor survival during squamous cell carcinoma progression in vivo
    • Crawford HC, Matrisian LM, Liaw L. Distinct roles of osteopontin in host defense activity and tumor survival during squamous cell carcinoma progression in vivo. Cancer Res. 1998;58:5206-5215.
    • (1998) Cancer Res , vol.58 , pp. 5206-5215
    • Crawford, H.C.1    Matrisian, L.M.2    Liaw, L.3
  • 78
    • 0029910184 scopus 로고    scopus 로고
    • Osteopontin expression in platelet-derived growth factor-stimulated vascular smooth muscle cells and carotid artery after balloon angioplasty
    • Wang X, Louden C, Ohlstein EH, Stadel JM, Gu JL, Yue TL. Osteopontin expression in platelet-derived growth factor-stimulated vascular smooth muscle cells and carotid artery after balloon angioplasty. Arterioscler Thromb Vasc Biol. 1996;16:1365-1372.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 1365-1372
    • Wang, X.1    Louden, C.2    Ohlstein, E.H.3    Stadel, J.M.4    Gu, J.L.5    Yue, T.L.6
  • 82
    • 0031906847 scopus 로고    scopus 로고
    • Evidence for a role of osteopontin in macrophage infiltration in response to pathological stimuli in vivo
    • Giachelli CM, Lombardi D, Johnson RJ, Murry CE, Almeida M. Evidence for a role of osteopontin in macrophage infiltration in response to pathological stimuli in vivo. Am J Pathol. 1998;152:353-358.
    • (1998) Am J Pathol , vol.152 , pp. 353-358
    • Giachelli, C.M.1    Lombardi, D.2    Johnson, R.J.3    Murry, C.E.4    Almeida, M.5
  • 83
    • 1142273152 scopus 로고    scopus 로고
    • Transient expression of osteopontin mRNA and protein in amoeboid microglia in developing rat brain
    • Choi JS, Cha JH, Park HJ, Chung JW, Chun MH, Lee MY. Transient expression of osteopontin mRNA and protein in amoeboid microglia in developing rat brain. Exp Brain Res. 2004;154:275-280.
    • (2004) Exp Brain Res , vol.154 , pp. 275-280
    • Choi, J.S.1    Cha, J.H.2    Park, H.J.3    Chung, J.W.4    Chun, M.H.5    Lee, M.Y.6
  • 84
    • 9044241690 scopus 로고    scopus 로고
    • Osteopontin at mineralized tissue interfaces in bone, teeth, and osseointegrated implants: Ultrastructural distribution and implications for mineralized tissue formation, turnover, and repair
    • McKee MD, Nanci A. Osteopontin at mineralized tissue interfaces in bone, teeth, and osseointegrated implants: ultrastructural distribution and implications for mineralized tissue formation, turnover, and repair. Microsc Res Tech. 1996;33:141-164.
    • (1996) Microsc Res Tech , vol.33 , pp. 141-164
    • McKee, M.D.1    Nanci, A.2
  • 89
    • 20244386058 scopus 로고    scopus 로고
    • Phosphorylation-dependent interaction of osteopontin with its receptors regulates macrophage migration and activation
    • Weber GF, Zawaideh S, Hikita S, Kumar VA, Cantor H, Ashkar S. Phosphorylation-dependent interaction of osteopontin with its receptors regulates macrophage migration and activation. J Leukoc Biol. 2002;72:752-761.
    • (2002) J Leukoc Biol , vol.72 , pp. 752-761
    • Weber, G.F.1    Zawaideh, S.2    Hikita, S.3    Kumar, V.A.4    Cantor, H.5    Ashkar, S.6
  • 91
    • 1642340048 scopus 로고    scopus 로고
    • Impaired anti-tumor cytotoxicity of macrophages from osteopontin-deficient mice
    • Bourassa B, Monaghan S, Rittling SR. Impaired anti-tumor cytotoxicity of macrophages from osteopontin-deficient mice. Cell Immunol. 2004;227:1-11.
    • (2004) Cell Immunol , vol.227 , pp. 1-11
    • Bourassa, B.1    Monaghan, S.2    Rittling, S.R.3
  • 92
    • 33947249865 scopus 로고    scopus 로고
    • A constitutive endogenous osteopontin production is important for macrophage function and differentiation
    • Nystrom T, Duner P, Hultgardh-Nilsson A. A constitutive endogenous osteopontin production is important for macrophage function and differentiation. Exp Cell Res. 2007.
    • (2007) Exp Cell Res
    • Nystrom, T.1    Duner, P.2    Hultgardh-Nilsson, A.3
  • 93
    • 0033555820 scopus 로고    scopus 로고
    • Osteopontin is associated with T cells in sarcoid granulomas and has T cell adhesive and cytokine-like properties in vitro
    • O'Regan AW, Chupp GL, Lowry JA, Goetschkes M, Mulligan N, Berman JS. Osteopontin is associated with T cells in sarcoid granulomas and has T cell adhesive and cytokine-like properties in vitro. J Immunol. 1999;162:1024-1031.
    • (1999) J Immunol , vol.162 , pp. 1024-1031
    • O'Regan, A.W.1    Chupp, G.L.2    Lowry, J.A.3    Goetschkes, M.4    Mulligan, N.5    Berman, J.S.6
  • 94
    • 0033780805 scopus 로고    scopus 로고
    • Osteopontin augments CD3-mediated interferon-gamma and CD40 ligand expression by T cells, which results in IL-12 production from peripheral blood mononuclear cells
    • O'Regan AW, Hayden JM, Berman JS. Osteopontin augments CD3-mediated interferon-gamma and CD40 ligand expression by T cells, which results in IL-12 production from peripheral blood mononuclear cells. J Leukoc Biol. 2000;68:495-502.
    • (2000) J Leukoc Biol , vol.68 , pp. 495-502
    • O'Regan, A.W.1    Hayden, J.M.2    Berman, J.S.3
  • 95
    • 33846998653 scopus 로고    scopus 로고
    • Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells
    • Hur EM, Youssef S, Haws ME, Zhang SY, Sobel RA, Steinman L. Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells. Nat Immunol. 2007;8:74-83.
    • (2007) Nat Immunol , vol.8 , pp. 74-83
    • Hur, E.M.1    Youssef, S.2    Haws, M.E.3    Zhang, S.Y.4    Sobel, R.A.5    Steinman, L.6
  • 98
    • 1642313676 scopus 로고    scopus 로고
    • Concerted regulation of inorganic pyrophosphate and osteopontin by akp2, enpp1, and ank: An integrated model of the pathogenesis of mineralization disorders
    • Harmey D, Hessle L, Narisawa S, Johnson KA, Terkeltaub R, Millan JL. Concerted regulation of inorganic pyrophosphate and osteopontin by akp2, enpp1, and ank: an integrated model of the pathogenesis of mineralization disorders. Am J Pathol. 2004;164:1199-1209.
    • (2004) Am J Pathol , vol.164 , pp. 1199-1209
    • Harmey, D.1    Hessle, L.2    Narisawa, S.3    Johnson, K.A.4    Terkeltaub, R.5    Millan, J.L.6
  • 101
    • 0034733562 scopus 로고    scopus 로고
    • Phosphorylation of osteopontin is required for inhibition of vascular smooth muscle cell calcification
    • Jono S, Peinado C, Giachelli CM. Phosphorylation of osteopontin is required for inhibition of vascular smooth muscle cell calcification. J Biol Chem. 2000;275:20197-20203.
    • (2000) J Biol Chem , vol.275 , pp. 20197-20203
    • Jono, S.1    Peinado, C.2    Giachelli, C.M.3
  • 102
    • 22344448703 scopus 로고    scopus 로고
    • Mitigation of ectopic calcification in osteopontin-deficient mice by exogenous osteopontin
    • Ohri R, Tung E, Rajachar R, Giachelli CM. Mitigation of ectopic calcification in osteopontin-deficient mice by exogenous osteopontin. Calcif Tissue Int. 2005;76:307-315.
    • (2005) Calcif Tissue Int , vol.76 , pp. 307-315
    • Ohri, R.1    Tung, E.2    Rajachar, R.3    Giachelli, C.M.4
  • 103
    • 0033524663 scopus 로고    scopus 로고
    • Calcification of vascular smooth muscle cell cultures: Inhibition by osteopontin
    • Wada T, McKee MD, Stietz S, Giachelli CM. Calcification of vascular smooth muscle cell cultures: inhibition by osteopontin. Circ Res. 1999;84:1-6.
    • (1999) Circ Res , vol.84 , pp. 1-6
    • Wada, T.1    McKee, M.D.2    Stietz, S.3    Giachelli, C.M.4
  • 104
    • 0035071294 scopus 로고    scopus 로고
    • Ectopic calcification: New concepts in cellular regulation
    • Giachelli CM. Ectopic calcification: new concepts in cellular regulation. Z Kardiol. 2001;90 Suppl 3:31-37.
    • (2001) Z Kardiol , vol.90 , Issue.SUPPL. 3 , pp. 31-37
    • Giachelli, C.M.1
  • 105
    • 0029239541 scopus 로고
    • Calcification of valved aortic allografts in rats: Effects of age, crosslinking,and inhibitors
    • Levy RJ, Qu X, Underwood T, Trachy J, Schoen FJ. Calcification of valved aortic allografts in rats: effects of age, crosslinking,and inhibitors. J Biomed Mater Res. 1995;29:217-226.
    • (1995) J Biomed Mater Res , vol.29 , pp. 217-226
    • Levy, R.J.1    Qu, X.2    Underwood, T.3    Trachy, J.4    Schoen, F.J.5
  • 107
    • 0037438638 scopus 로고    scopus 로고
    • Gene therapy of apolipoprotein E-deficient mice using a novel macrophage-specific retroviral vector
    • Gough PJ, Raines EW. Gene therapy of apolipoprotein E-deficient mice using a novel macrophage-specific retroviral vector. Blood. 2003;101:485-491.
    • (2003) Blood , vol.101 , pp. 485-491
    • Gough, P.J.1    Raines, E.W.2
  • 109
    • 0029146741 scopus 로고
    • Osteopontin mRNA expression in a chemically-induced model of atherogenesis
    • Parrish AR, Ramos KS. Osteopontin mRNA expression in a chemically-induced model of atherogenesis. Ann N Y Acad Sci. 1995;760:354-356.
    • (1995) Ann N Y Acad Sci , vol.760 , pp. 354-356
    • Parrish, A.R.1    Ramos, K.S.2
  • 111
    • 0037432181 scopus 로고    scopus 로고
    • Osteopontin transgenic mice fed a high-cholesterol diet develop early fatty-streak lesions
    • Isoda K, Kamezawa Y, Ayaori M, Kusuhara M, Tada N, Ohsuzu F. Osteopontin transgenic mice fed a high-cholesterol diet develop early fatty-streak lesions. Circulation. 2003;107:679-681.
    • (2003) Circulation , vol.107 , pp. 679-681
    • Isoda, K.1    Kamezawa, Y.2    Ayaori, M.3    Kusuhara, M.4    Tada, N.5    Ohsuzu, F.6
  • 113
    • 1842559450 scopus 로고    scopus 로고
    • Extracellular matrix components in atherosclerotic arteries of Apo E/LDL receptor deficient mice: An immunohistochemical study
    • Strom A, Ahlqvist E, Franzen A, Heinegard D, Hultgardh-Nilsson A. Extracellular matrix components in atherosclerotic arteries of Apo E/LDL receptor deficient mice: an immunohistochemical study. Histol Histopathol. 2004;19:337-347.
    • (2004) Histol Histopathol , vol.19 , pp. 337-347
    • Strom, A.1    Ahlqvist, E.2    Franzen, A.3    Heinegard, D.4    Hultgardh-Nilsson, A.5
  • 114
    • 31344469271 scopus 로고    scopus 로고
    • Atherosclerosis and proteinase activation
    • Dollery CM, Libby P. Atherosclerosis and proteinase activation. Cardiovasc Res. 2006;69:625-635.
    • (2006) Cardiovasc Res , vol.69 , pp. 625-635
    • Dollery, C.M.1    Libby, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.