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Volumn 10, Issue 10, 2012, Pages 2101-2112

New synthetic approach to paullones and characterization of their SIRT1 inhibitory activity

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE LEUKEMIA; AMIDE FORMATION; C-H ACTIVATION; CELL CYCLE; ENZYMATIC ASSAY; IN-VITRO; INHIBITORY ACTIVITY; INHIBITORY PROFILES; ONE POT; SUZUKI-MIYAURA CROSS-COUPLING; SYNTHETIC APPROACH;

EID: 84857531968     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/c2ob06695e     Document Type: Article
Times cited : (52)

References (82)
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    • 2, CsOAc, DMA) with aryl iodides in both intra- and intermolecular fashion led to dehalogenated (21%) or recovered starting materials
    • X. Wang D. V. Gribkov D. Sames J. Org. Chem. 2007 72 1476
    • (2007) J. Org. Chem. , vol.72 , pp. 1476
    • Wang, X.1    Gribkov, D.V.2    Sames, D.3
  • 67
    • 34249936878 scopus 로고    scopus 로고
    • 2, excess silver oxidant (AgOAc, 3 equiv.) to favor C-2 substitution and excess pivalic acid (6 equiv) also led to recovered starting material
    • D. R. Stuart K. Fagnou Science 2007 316 1172
    • (2007) Science , vol.316 , pp. 1172
    • Stuart, D.R.1    Fagnou, K.2
  • 68
    • 41449108490 scopus 로고    scopus 로고
    • 2O and o-nitrobenzoic acid (to generate in situ the corresponding silver(I) carboxylate) led to starting material for intermolecular reactions and partial decomposition in case of the intramolecular version (see ESI)
    • N. Lebrasseur I. Larrosa J. Am. Chem. Soc. 2008 130 2926
    • (2008) J. Am. Chem. Soc. , vol.130 , pp. 2926
    • Lebrasseur, N.1    Larrosa, I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.