Development and characterization of lysine based tripeptide analogues as inhibitors of Sir2 activity

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 23, 2009, Pages 8060-8072

  Chakrabarty, Subhra Prakash ^a   Ramapanicker, Ramesh ^b   Mishra, Roli ^b   Chandrasekaran, Srinivasan ^b   Balaram, Hemalatha ^a  

^a JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH   (India)

^b INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

Carbohydrate conjugates; Click chemistry; Parabolic inhibition; Peptide inhibitors; Sir2 activity

Indexed keywords

LYSINE; NICOTINAMIDE; PROTEIN INHIBITOR; SILENT INFORMATION REGULATOR PROTEIN 2; TRIPEPTIDE DERIVATIVE;

ARTICLE; CHEMICAL MODIFICATION; COMPETITIVE INHIBITION; CYCLOADDITION; DRUG MECHANISM; NONHUMAN; PLASMODIUM FALCIPARUM;

ANTIMALARIALS; BINDING SITES; BINDING, COMPETITIVE; ENZYME INHIBITORS; KINETICS; LYSINE; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; OLIGOPEPTIDES; PLASMODIUM FALCIPARUM; SIRTUIN 2; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

PLASMODIUM FALCIPARUM;

EID: 71849111550     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.10.003     Document Type: Article

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