메뉴 건너뛰기




Volumn 18, Issue 7, 2012, Pages 981-1004

Role of the Renin-Angiotensin-Aldosterone system in the pathogenesis of atherosclerosis

Author keywords

Aldosterone; Angiotensin; Atherosclerosis; RAAS; Renin

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ALDOSTERONE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR ANTAGONIST; ANGIOTENSINOGEN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FENOFIBRATE; PRORENIN; PRORENIN RECEPTOR; REACTIVE OXYGEN METABOLITE; THIAZIDE DIURETIC AGENT;

EID: 84857136034     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/138161212799436467     Document Type: Review
Times cited : (62)

References (294)
  • 1
    • 0025027754 scopus 로고
    • Recruitment of renin gene-expressing cells in adult rat kidneys
    • Gomez RA, Chevalier RL, Everett AD, et al. Recruitment of renin gene-expressing cells in adult rat kidneys. Am J Physiol 1990; 259: F660-5.
    • (1990) Am J Physiol , vol.259
    • Gomez, R.A.1    Chevalier, R.L.2    Everett, A.D.3
  • 2
    • 0027056387 scopus 로고
    • Renin release from microdissected superficial, midcortical, and juxtamedullary afferent arterioles in rabbits
    • Nushiro N, Ito S, Misawa S, Abe K. Renin release from microdissected superficial, midcortical, and juxtamedullary afferent arterioles in rabbits. Nihon Jinzo Gakkai Shi 1992; 34: 1113-6.
    • (1992) Nihon Jinzo Gakkai Shi , vol.34 , pp. 1113-1116
    • Nushiro, N.1    Ito, S.2    Misawa, S.3    Abe, K.4
  • 4
    • 0038053724 scopus 로고    scopus 로고
    • A novel angiotensinconverting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9
    • Donoghue M, Hsieh F, Baronas E, et al. A novel angiotensinconverting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ Res 2000; 87: E1-9.
    • (2000) Circ Res , vol.87
    • Donoghue, M.1    Hsieh, F.2    Baronas, E.3
  • 5
    • 0037142101 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 is an essential regulator of heart function
    • Crackower MA, Sarao R, Oudit GY, et al. Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature 2002; 417: 822-8.
    • (2002) Nature , vol.417 , pp. 822-828
    • Crackower, M.A.1    Sarao, R.2    Oudit, G.Y.3
  • 6
    • 0030594604 scopus 로고    scopus 로고
    • Angiotensin receptors and their antagonists
    • Goodfriend TL, Elliott ME, Catt KJ, et al. Angiotensin receptors and their antagonists. N Engl J Med 1996; 334: 1649-54.
    • (1996) N Engl J Med , vol.334 , pp. 1649-1654
    • Goodfriend, T.L.1    Elliott, M.E.2    Catt, K.J.3
  • 7
    • 0024446505 scopus 로고
    • Selective inhibition of angiotensin II-mediated vasoconstriction by lipoxygenase blockade
    • Stern N, Golub M, Nozawa K, et al. Selective inhibition of angiotensin II-mediated vasoconstriction by lipoxygenase blockade. Am J Physiol 1989; 257: H434-43.
    • (1989) Am J Physiol , vol.257
    • Stern, N.1    Golub, M.2    Nozawa, K.3
  • 8
    • 0026589950 scopus 로고
    • Morphometric analysis of the actions of angiotensin II on renal arterioles and glomeruli
    • Denton KM, Fennessy PA, Alcorn D, et al. Morphometric analysis of the actions of angiotensin II on renal arterioles and glomeruli. Am J Physiol 1992; 262: F367-72.
    • (1992) Am J Physiol , vol.262
    • Denton, K.M.1    Fennessy, P.A.2    Alcorn, D.3
  • 9
    • 0024378763 scopus 로고
    • Interaction of vasopressin and angiotensin II in stimulation of prostacyclin synthesis in vascular smooth muscle cells
    • Vallotton MB, Gerber-Wicht C, Dolci W, Wüthrich RP. Interaction of vasopressin and angiotensin II in stimulation of prostacyclin synthesis in vascular smooth muscle cells. Am J Physiol 1989; 257: E617-24.
    • (1989) Am J Physiol , vol.257
    • Vallotton, M.B.1    Gerber-Wicht, C.2    Dolci, W.3    Wüthrich, R.P.4
  • 10
    • 78651363548 scopus 로고    scopus 로고
    • Angiotensin II receptors and drug discovery incardiovascular disease
    • Dasgupta C, Zhang L. Angiotensin II receptors and drug discovery incardiovascular disease. Drug Discov Today 2011; 16: 22-34.
    • (2011) Drug Discov Today , vol.16 , pp. 22-34
    • Dasgupta, C.1    Zhang, L.2
  • 11
    • 0029026164 scopus 로고
    • Disulfide bridges in extracellular domains of angiotensin II receptor type IA
    • Ohyama K, Yamano Y, Sano T, et al. Disulfide bridges in extracellular domains of angiotensin II receptor type IA. Regul Pept 1995; 57: 141-7.
    • (1995) Regul Pept , vol.57 , pp. 141-147
    • Ohyama, K.1    Yamano, Y.2    Sano, T.3
  • 12
    • 0037834636 scopus 로고    scopus 로고
    • Angiotensin receptors: Distribution,signaling and function
    • Dinh DT, Frauman AG, Johnston CI, Fabiani ME. Angiotensin receptors: distribution,signaling and function. Clin Sci 2001; 100: 481-92.
    • (2001) Clin Sci , vol.100 , pp. 481-492
    • Dinh, D.T.1    Frauman, A.G.2    Johnston, C.I.3    Fabiani, M.E.4
  • 13
    • 0030341151 scopus 로고    scopus 로고
    • Distribution and signaltransduction of angiotensin II AT1 and AT2 receptors
    • Capponi AM. Distribution and signaltransduction of angiotensin II AT1 and AT2 receptors. Blood Press Suppl 1996; 2: 41-6.
    • (1996) Blood Press Suppl , vol.2 , pp. 41-46
    • Capponi, A.M.1
  • 14
    • 0029917332 scopus 로고    scopus 로고
    • Importance of tyrosine phosphorylation in angiotensin II type 1 receptor signaling
    • Schieffer B, Paxton WG, Marrero MB and Bernstein KE. Importance of tyrosine phosphorylation in angiotensin II type 1 receptor signaling. Hypertension 1996; 27: 476-80.
    • (1996) Hypertension , vol.27 , pp. 476-480
    • Schieffer, B.1    Paxton, W.G.2    Marrero, M.B.3    Bernstein, K.E.4
  • 15
    • 0027197933 scopus 로고
    • Signal transduction pathways of angiotensin II--induced c-fos gene expression in cardiac myocytes in vitro. Roles of phospholipid-derived second messengers
    • Sadoshima J, Izumo S. Signal transduction pathways of angiotensin II--induced c-fos gene expression in cardiac myocytes in vitro. Roles of phospholipid-derived second messengers. Circ Res 1993; 73: 424-38.
    • (1993) Circ Res , vol.73 , pp. 424-438
    • Sadoshima, J.1    Izumo, S.2
  • 16
    • 0030667099 scopus 로고    scopus 로고
    • Angiotensin type 2 receptors are reexpressed by cardiac fibroblasts from failing myopathic hamster hearts and inhibit cell growth and fibrillar collagen metabolism
    • Ohkubo N, Matsubara H, Nozawa Y, et al. Angiotensin type 2 receptors are reexpressed by cardiac fibroblasts from failing myopathic hamster hearts and inhibit cell growth and fibrillar collagen metabolism. Circulation 1997; 96: 3954-62.
    • (1997) Circulation , vol.96 , pp. 3954-3962
    • Ohkubo, N.1    Matsubara, H.2    Nozawa, Y.3
  • 17
    • 0035955732 scopus 로고    scopus 로고
    • The angiotensin II AT2 receptor is an AT1 receptor antagonist
    • AbdAlla S, Lother H, Abdel-tawab AM, Quitterer U. The angiotensin II AT2 receptor is an AT1 receptor antagonist. J Biol Chem 2001; 276: 39721-6.
    • (2001) J Biol Chem , vol.276 , pp. 39721-39726
    • Abdalla, S.1    Lother, H.2    Abdel-Tawab, A.M.3    Quitterer, U.4
  • 18
    • 0038518483 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptor deficiency exacerbates heart failure and reduces survival after acute myocardial infarction in mice
    • Adachi Y, Saito Y, Kishimoto I, et al. Angiotensin II type 2 receptor deficiency exacerbates heart failure and reduces survival after acute myocardial infarction in mice. Circulation 2003; 107: 2406-8.
    • (2003) Circulation , vol.107 , pp. 2406-2408
    • Adachi, Y.1    Saito, Y.2    Kishimoto, I.3
  • 19
    • 0037072451 scopus 로고    scopus 로고
    • Role of angiotensin IIregulated apoptosis through distinct AT1 and AT2 receptors in neointimal formation
    • Suzuki J, Iwai M, Nakagami H, et al. Role of angiotensin IIregulated apoptosis through distinct AT1 and AT2 receptors in neointimal formation. Circulation 2002; 106: 847-53.
    • (2002) Circulation , vol.106 , pp. 847-853
    • Suzuki, J.1    Iwai, M.2    Nakagami, H.3
  • 20
    • 0032698983 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptor overexpression activates the vascular kinin system and causes vasodilation
    • Tsutsumi Y, Matsubara H, Masaki H, et al. Angiotensin II type 2 receptor overexpression activates the vascular kinin system and causes vasodilation. J Clin Invest 1999; 104: 925-35.
    • (1999) J Clin Invest , vol.104 , pp. 925-935
    • Tsutsumi, Y.1    Matsubara, H.2    Masaki, H.3
  • 21
    • 0035984927 scopus 로고    scopus 로고
    • AT(2) receptor-dependent vasodilation ismediated by activation of vascular kinin generation under flow conditions
    • Katada J, and Majima M. (2002) AT(2) receptor-dependent vasodilation ismediated by activation of vascular kinin generation under flow conditions. Br J Pharmacol 2002;136: 484-91.
    • (2002) Br J Pharmacol 2002 , vol.136 , pp. 484-491
    • Katada, J.1    Majima, M.2
  • 22
    • 3042820768 scopus 로고    scopus 로고
    • Flow-dependent dilation mediated by endogenous kinins requires angiotensin AT2 receptors
    • Bergaya S, Hilgers RH, Meneton P, et al. Flow-dependent dilation mediated by endogenous kinins requires angiotensin AT2 receptors. Circ Res 2004; 94: 1623-9.
    • (2004) Circ Res , vol.94 , pp. 1623-1629
    • Bergaya, S.1    Hilgers, R.H.2    Meneton, P.3
  • 23
    • 33748160210 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptor-bradykinin B2 receptor functional heterodimerization
    • Abadir PM, Periasamy A, Carey RM, Siragy HM. Angiotensin II type 2 receptor-bradykinin B2 receptor functional heterodimerization. Hypertension 2006; 48: 316-22.
    • (2006) Hypertension , vol.48 , pp. 316-322
    • Abadir, P.M.1    Periasamy, A.2    Carey, R.M.3    Siragy, H.M.4
  • 25
    • 0142139293 scopus 로고    scopus 로고
    • Ventricular-specific expression of angiotensin II type 2 receptors causes dilated cardiomyopathy and heart failure in transgenic mice
    • Yan X, Price RL, Nakayama M, et al. Ventricular-specific expression of angiotensin II type 2 receptors causes dilated cardiomyopathy and heart failure in transgenic mice. Am J Physiol Heart Circ Physiol 2003; 285: H2179-87.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • Yan, X.1    Price, R.L.2    Nakayama, M.3
  • 26
    • 0026595119 scopus 로고
    • Identification and characterization of a new binding site for angiotensin II in mouse neuroblastoma neuro-2A cells
    • Chaki S, Inagami T. Identification and characterization of a new binding site for angiotensin II in mouse neuroblastoma neuro-2A cells. Biochem Biophys Res Commun 1992; 182: 388-94.
    • (1992) Biochem Biophys Res Commun , vol.182 , pp. 388-394
    • Chaki, S.1    Inagami, T.2
  • 28
  • 29
    • 0037478671 scopus 로고    scopus 로고
    • Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas
    • Santos RA, Simoes e Silva AC, Maric C, et al. Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc Natl Acad Sci USA 2003; 100: 8258-63.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8258-8263
    • Santos, R.A.1    Simoes e Silva, A.C.2    Maric, C.3
  • 30
    • 20244388129 scopus 로고    scopus 로고
    • G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor
    • Kostenis E, Milligan G, Christopoulos A, et al. G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor. Circulation 2005; 111: 1806-13.
    • (2005) Circulation , vol.111 , pp. 1806-1813
    • Kostenis, E.1    Milligan, G.2    Christopoulos, A.3
  • 31
    • 33646161714 scopus 로고    scopus 로고
    • Impairment of in vitro and in vivo heart function in angiotensin-(1-7) receptor MAS knockout mice
    • Santos RA, Castro CH, Gava E, et al. Impairment of in vitro and in vivo heart function in angiotensin-(1-7) receptor MAS knockout mice. Hypertension 2006; 47: 996-1002.
    • (2006) Hypertension , vol.47 , pp. 996-1002
    • Santos, R.A.1    Castro, C.H.2    Gava, E.3
  • 32
    • 33846987938 scopus 로고    scopus 로고
    • Prevention of angiotensin IIinduced cardiac remodeling by angiotensin-(1-7)
    • Grobe JL, Mecca AP, Lingis M, et al. Prevention of angiotensin IIinduced cardiac remodeling by angiotensin-(1-7). Am J Physiol Heart Circ Physiol 2007; 292: H736-42.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Grobe, J.L.1    Mecca, A.P.2    Lingis, M.3
  • 33
    • 0035347330 scopus 로고    scopus 로고
    • Angiotensin III: A central regulator of vasopressin release and blood pressure
    • Reaux A, Fournie-Zaluski MC, Llorens-Cortes C. Angiotensin III: a central regulator of vasopressin release and blood pressure. Trends Endocrinol Metab 2001; 12: 157-62.
    • (2001) Trends Endocrinol Metab , vol.12 , pp. 157-162
    • Reaux, A.1    Fournie-Zaluski, M.C.2    Llorens-Cortes, C.3
  • 34
    • 0027208946 scopus 로고
    • Angiotensin type 2 receptors mediate depressor phase of biphasic pressure response to angiotensin
    • Scheuer DA, Perrone MH. Angiotensin type 2 receptors mediate depressor phase of biphasic pressure response to angiotensin. Am J Physiol 1993; 264: R917-23.
    • (1993) Am J Physiol , vol.264 , pp. 917-923
    • Scheuer, D.A.1    Perrone, M.H.2
  • 35
    • 18244391184 scopus 로고    scopus 로고
    • Angiotensin-(1-7) acts as a vasodepressor agent via angiotensin II type 2 receptors in conscious rats
    • Walters PE, Gaspari TA, Widdop RE. Angiotensin-(1-7) acts as a vasodepressor agent via angiotensin II type 2 receptors in conscious rats. Hypertension 2005; 45: 960-6.
    • (2005) Hypertension , vol.45 , pp. 960-966
    • Walters, P.E.1    Gaspari, T.A.2    Widdop, R.E.3
  • 37
    • 0037817386 scopus 로고    scopus 로고
    • Angiotensin AT4 ligands are potent, competitive inhibitors of insulin regulated aminopeptidase (IRAP)
    • Lew RA, Mustafa T, Ye S, McDowall SG, Chai SY, Albiston AL. Angiotensin AT4 ligands are potent, competitive inhibitors of insulin regulated aminopeptidase (IRAP). J Neurochem 2003; 86: 344-50.
    • (2003) J Neurochem , vol.86 , pp. 344-350
    • Lew, R.A.1    Mustafa, T.2    Ye, S.3    McDowall, S.G.4    Chai, S.Y.5    Albiston, A.L.6
  • 38
    • 0037447801 scopus 로고    scopus 로고
    • Angiotensin IV interacts with a juxtamembrane site on AT(4)/IRAP suggesting an allosteric mechanism of enzyme modulation
    • Caron AZ, Arguin G, Guillemette G. Angiotensin IV interacts with a juxtamembrane site on AT(4)/IRAP suggesting an allosteric mechanism of enzyme modulation. Regul Pept 2003; 113: 9-15.
    • (2003) Regul Pept , vol.113 , pp. 9-15
    • Caron, A.Z.1    Arguin, G.2    Guillemette, G.3
  • 40
    • 19044369325 scopus 로고    scopus 로고
    • Angiotensin IV activates the nuclear transcription factor-kappaB and related proinflammatory genes in vascular smooth muscle cells
    • Esteban V, Ruperez M, Sánchez-López E, et al. Angiotensin IV activates the nuclear transcription factor-kappaB and related proinflammatory genes in vascular smooth muscle cells. Circ Res 2005; 96: 965-73.
    • (2005) Circ Res , vol.96 , pp. 965-973
    • Esteban, V.1    Ruperez, M.2    Sánchez-López, E.3
  • 41
    • 0033696010 scopus 로고    scopus 로고
    • Angiotensin IV-mediated pulmonary artery vasorelaxation is due to endothelial intracellular calcium release
    • Chen S, Patel JM, Block ER. Angiotensin IV-mediated pulmonary artery vasorelaxation is due to endothelial intracellular calcium release. Am J Physiol Lung Cell Mol Physiol 2000; 279: L849-56.
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.279
    • Chen, S.1    Patel, J.M.2    Block, E.R.3
  • 42
    • 0031589846 scopus 로고    scopus 로고
    • Angiotensin II-and IV induced changes in cerebral blood flow. Roles of AT1, AT2, and AT4 receptor subtypes
    • Kramár EA, Harding JW, Wright JW. Angiotensin II-and IV induced changes in cerebral blood flow. Roles of AT1, AT2, and AT4 receptor subtypes. Regul Pept 1997; 68: 131-8.
    • (1997) Regul Pept , vol.68 , pp. 131-138
    • Kramár, E.A.1    Harding, J.W.2    Wright, J.W.3
  • 43
    • 0033055979 scopus 로고    scopus 로고
    • Angiotensin II-stimulated nitric oxide release from porcine pulmonary endothelium is mediated by angiotensin IV
    • Hill-Kapturczak N, Kapturczak MH, Block ER, et al. Angiotensin II-stimulated nitric oxide release from porcine pulmonary endothelium is mediated by angiotensin IV. J Am Soc Nephrol 1999; 10: 481-91.
    • (1999) J Am Soc Nephrol , vol.10 , pp. 481-491
    • Hill-Kapturczak, N.1    Kapturczak, M.H.2    Block, E.R.3
  • 46
    • 22444431688 scopus 로고    scopus 로고
    • Human mineralocorticoid receptor expression renders cells responsive for nongenotropic aldosterone actions
    • Grossmann C, Benesic A, Krug AW, et al. Human mineralocorticoid receptor expression renders cells responsive for nongenotropic aldosterone actions. Mol Endocrinol 2005; 19: 1697-710.
    • (2005) Mol Endocrinol , vol.19 , pp. 1697-1710
    • Grossmann, C.1    Benesic, A.2    Krug, A.W.3
  • 47
    • 0842311501 scopus 로고    scopus 로고
    • Endothelium-derived nitric oxide modulates vascular action of aldosterone in renal arteriole
    • Arima S, Kohagura K, Xu HL, et al. Endothelium-derived nitric oxide modulates vascular action of aldosterone in renal arteriole. Hypertension 2004; 43: 352-7.
    • (2004) Hypertension , vol.43 , pp. 352-357
    • Arima, S.1    Kohagura, K.2    Xu, H.L.3
  • 48
    • 55449125775 scopus 로고    scopus 로고
    • Aldosterone enhances ligandstimulated nitric oxide production in endothelial cells
    • Mutoh A, Isshiki M, Fujita T. Aldosterone enhances ligandstimulated nitric oxide production in endothelial cells. Hypertens Res 2008; 31: 1811-20.
    • (2008) Hypertens Res , vol.31 , pp. 1811-1820
    • Mutoh, A.1    Isshiki, M.2    Fujita, T.3
  • 50
    • 0242525727 scopus 로고    scopus 로고
    • Aldosterone regulates vascular reactivity: Short-term effects mediated by phosphatidylinositol 3-kinase-dependent nitric oxide synthase activation
    • Liu SL, Schmuck S, Chorazcyzewski JZ, Gros R, Feldman RD. Aldosterone regulates vascular reactivity: short-term effects mediated by phosphatidylinositol 3-kinase-dependent nitric oxide synthase activation. Circulation 2003; 103: 2400-6.
    • (2003) Circulation , vol.103 , pp. 2400-2406
    • Liu, S.L.1    Schmuck, S.2    Chorazcyzewski, J.Z.3    Gros, R.4    Feldman, R.D.5
  • 51
  • 52
    • 33846963787 scopus 로고    scopus 로고
    • Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity
    • Leopold JA, Dam A, Maron BA, et al. Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity. J Nat Med 2007;13:189-97.
    • (2007) J Nat Med , vol.13 , pp. 189-197
    • Leopold, J.A.1    Dam, A.2    Maron, B.A.3
  • 56
    • 77951879058 scopus 로고    scopus 로고
    • Aldosterone: Effects on the kidney and cardiovascular system
    • Briet M, Schiffrin EL. Aldosterone: effects on the kidney and cardiovascular system. Nat Rev Nephrol 2010; 6: 261-73.
    • (2010) Nat Rev Nephrol , vol.6 , pp. 261-273
    • Briet, M.1    Schiffrin, E.L.2
  • 57
    • 33644773392 scopus 로고    scopus 로고
    • The relationship between aldosterone, oxidative stress, and inflammation in chronic, stable human heart failure
    • Kotlyar E, Vita JA, Winter MR, et al. The relationship between aldosterone, oxidative stress, and inflammation in chronic, stable human heart failure. J Card Fail 2006; 12: 122-7.
    • (2006) J Card Fail , vol.12 , pp. 122-127
    • Kotlyar, E.1    Vita, J.A.2    Winter, M.R.3
  • 59
    • 0022337756 scopus 로고
    • Effect of aldosterone on vascular angiotensin II receptors in the rat
    • Schiffrin EL, Franks DJ, Gutkowska J. Effect of aldosterone on vascular angiotensin II receptors in the rat. Can J Physiol Pharmacol 1985; 63:1522-7.
    • (1985) Can J Physiol Pharmacol , vol.63 , pp. 1522-1527
    • Schiffrin, E.L.1    Franks, D.J.2    Gutkowska, J.3
  • 60
    • 0028089861 scopus 로고
    • Mechanisms of enhanced angiotensin IIstimulated signal transduction in vascular smooth muscle by aldosterone
    • Ullian ME, Fine JJ. Mechanisms of enhanced angiotensin IIstimulated signal transduction in vascular smooth muscle by aldosterone. J Cell Physiol 1994; 161: 201-8.
    • (1994) J Cell Physiol , vol.161 , pp. 201-208
    • Ullian, M.E.1    Fine, J.J.2
  • 61
    • 0035838423 scopus 로고    scopus 로고
    • Aldosterone induces angiotensin-converting-enzyme gene expression in cultured neonatal rat cardiocytes
    • Harada E, Yoshimura M, Yasue H, et al. Aldosterone induces angiotensin-converting-enzyme gene expression in cultured neonatal rat cardiocytes. Circulation 2001; 104: 137-9.
    • (2001) Circulation , vol.104 , pp. 137-139
    • Harada, E.1    Yoshimura, M.2    Yasue, H.3
  • 62
    • 35548992302 scopus 로고    scopus 로고
    • Cross-talk between aldosterone and angiotensin II in vascular smooth muscle cell senescence
    • Min LJ, Mogi M, Iwanami J, et al. Cross-talk between aldosterone and angiotensin II in vascular smooth muscle cell senescence. Cardiovasc Res 2007; 76: 506-16.
    • (2007) Cardiovasc Res , vol.76 , pp. 506-516
    • Min, L.J.1    Mogi, M.2    Iwanami, J.3
  • 63
    • 52449122086 scopus 로고    scopus 로고
    • Aldosterone and angiotensin II synergistically stimulate migration in vascular smooth muscle cells through c-Src-regulated redox-sensitive RhoA pathways
    • Montezano AC, Callera GE, Yogi A, et al. Aldosterone and angiotensin II synergistically stimulate migration in vascular smooth muscle cells through c-Src-regulated redox-sensitive RhoA pathways. Arterioscler Thromb Vasc Biol 2008; 28: 1511-8.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1511-1518
    • Montezano, A.C.1    Callera, G.E.2    Yogi, A.3
  • 64
    • 24744471859 scopus 로고    scopus 로고
    • Aldosterone and angiotensin II synergistically induce mitogenic response in vascular smooth muscle cells
    • Min LJ, Mogi M, Li JM, Iwanami J, Iwai M, Horiuchi M. Aldosterone and angiotensin II synergistically induce mitogenic response in vascular smooth muscle cells. Circ Res 2005; 97: 434-42.
    • (2005) Circ Res , vol.97 , pp. 434-442
    • Min, L.J.1    Mogi, M.2    Li, J.M.3    Iwanami, J.4    Iwai, M.5    Horiuchi, M.6
  • 65
    • 70350743265 scopus 로고    scopus 로고
    • Aldosteroneinduced activation of signaling pathways requires activity of angiotensin type 1a receptors
    • Lemarié CA, Simeone SM, Nikonova A, et al. Aldosteroneinduced activation of signaling pathways requires activity of angiotensin type 1a receptors. Circ Res 2009; 105: 852-9.
    • (2009) Circ Res , vol.105 , pp. 852-859
    • Lemarié, C.A.1    Simeone, S.M.2    Nikonova, A.3
  • 67
  • 69
    • 42649088714 scopus 로고    scopus 로고
    • Renin and prorenin disappearance in humans post-nephrectomy: Evidence for binding?
    • Krop M, de Bruyn JH, Derkx FH, Danser AH. Renin and prorenin disappearance in humans post-nephrectomy: evidence for binding? Front Biosci 2008; 13: 3931-9.
    • (2008) Front Biosci , vol.13 , pp. 3931-3939
    • Krop, M.1    de Bruyn, J.H.2    Derkx, F.H.3    Danser, A.H.4
  • 70
    • 0029883537 scopus 로고    scopus 로고
    • Cathepsin B is a prorenin processing enzyme
    • Neves FA, Duncan KG, Baxter JD. Cathepsin B is a prorenin processing enzyme. Hypertension 1996; 27: 514-7.
    • (1996) Hypertension , vol.27 , pp. 514-517
    • Neves, F.A.1    Duncan, K.G.2    Baxter, J.D.3
  • 71
    • 0027946713 scopus 로고
    • Proteolytic processing of human prorenin in renal and non-renal tissues
    • Reudelhuber TL, Ramla D, Chiu L, Mercure C, Seidah NG. Proteolytic processing of human prorenin in renal and non-renal tissues. Kidney Int 1994; 46: 1522-4.
    • (1994) Kidney Int , vol.46 , pp. 1522-1524
    • Reudelhuber, T.L.1    Ramla, D.2    Chiu, L.3    Mercure, C.4    Seidah, N.G.5
  • 72
    • 78649362445 scopus 로고    scopus 로고
    • Cardiovascular and renal pathologic implications of prorenin, renin, and the (pro)renin receptor: Promising young players from the old renin-angiotensin-aldosterone system
    • Balakumar P, Jagadeesh G. Cardiovascular and renal pathologic implications of prorenin, renin, and the (pro)renin receptor: promising young players from the old renin-angiotensin-aldosterone system. J Cardiovasc Pharmacol 2010; 56: 570-9.
    • (2010) J Cardiovasc Pharmacol , vol.56 , pp. 570-579
    • Balakumar, P.1    Jagadeesh, G.2
  • 73
    • 33646501526 scopus 로고    scopus 로고
    • Renin/prorenin receptors
    • Nguyen G. Renin/prorenin receptors. Kidney Int 2006; 69: 1503-6.
    • (2006) Kidney Int , vol.69 , pp. 1503-1506
    • Nguyen, G.1
  • 74
    • 54049106595 scopus 로고    scopus 로고
    • Cardiovascular effects of prorenin blockade in genetically spontaneously hypertensive rats on normal and high-salt diet
    • Susic D, Zhou X, Frohlich ED, Lippton H, Knight M. Cardiovascular effects of prorenin blockade in genetically spontaneously hypertensive rats on normal and high-salt diet. Am J Physiol Heart Circ Physiol 2008; 295: H1117-H1121.
    • (2008) Am J Physiol Heart Circ Physiol , vol.295
    • Susic, D.1    Zhou, X.2    Frohlich, E.D.3    Lippton, H.4    Knight, M.5
  • 75
    • 0036266596 scopus 로고    scopus 로고
    • Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
    • Nguyen G, Delarue F, Burcklé C, Bouzhir L, Giller T, Sraer JD. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 2002; 109: 1417-27.
    • (2002) J Clin Invest , vol.109 , pp. 1417-1427
    • Nguyen, G.1    Delarue, F.2    Burcklé, C.3    Bouzhir, L.4    Giller, T.5    Sraer, J.D.6
  • 76
    • 0035005608 scopus 로고    scopus 로고
    • High-affinity prorenin binding to cardiac man-6-P/IGF-II receptors precedes proteolytic activation to renin
    • Saris JJ, Derkx FH, De Bruin RJ, et al. High-affinity prorenin binding to cardiac man-6-P/IGF-II receptors precedes proteolytic activation to renin. Am J Physiol Heart Circ Physiol 2001; 280: H1706-15.
    • (2001) Am J Physiol Heart Circ Physiol , vol.280
    • Saris, J.J.1    Derkx, F.H.2    de Bruin, R.J.3
  • 77
    • 0036852758 scopus 로고    scopus 로고
    • Prorenin uptake in the heart: A prerequisite for local angiotensin generation?
    • Jan Danser AH, Saris JJ. Prorenin uptake in the heart: a prerequisite for local angiotensin generation? J Mol Cell Cardiol 2002; 34: 1463-72.
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 1463-1472
    • Jan Danser, A.H.1    Saris, J.J.2
  • 78
    • 0037205323 scopus 로고    scopus 로고
    • Functional significance of prorenin internalization in the rat heart
    • Peters J, Farrenkopf R, Clausmeyer S, et al. Functional significance of prorenin internalization in the rat heart. Circ Res 2002; 90: 1135-41.
    • (2002) Circ Res , vol.90 , pp. 1135-1141
    • Peters, J.1    Farrenkopf, R.2    Clausmeyer, S.3
  • 79
    • 40649124722 scopus 로고    scopus 로고
    • Physiology and pharmacology of the (pro)renin receptor
    • Nguyen G, Contrepas A. Physiology and pharmacology of the (pro)renin receptor. Curr Opin Pharmacol 2008; 8: 127-32.
    • (2008) Curr Opin Pharmacol , vol.8 , pp. 127-132
    • Nguyen, G.1    Contrepas, A.2
  • 80
    • 78049423569 scopus 로고    scopus 로고
    • Potential role of the (pro)renin receptor in cardiovascular and kidney diseases
    • Cousin C, Bracquart D, Contrepas A, Nguyen G. Potential role of the (pro)renin receptor in cardiovascular and kidney diseases. J Nephrol 2010; 23: 508-13.
    • (2010) J Nephrol , vol.23 , pp. 508-513
    • Cousin, C.1    Bracquart, D.2    Contrepas, A.3    Nguyen, G.4
  • 81
    • 39749098706 scopus 로고    scopus 로고
    • Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide
    • Feldt S, Batenburg WW, Mazak I, et al. Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide. Hypertension 2008; 51: 682-8.
    • (2008) Hypertension , vol.51 , pp. 682-688
    • Feldt, S.1    Batenburg, W.W.2    Mazak, I.3
  • 82
    • 37849044605 scopus 로고    scopus 로고
    • (Pro)renin receptormediated activation of mitogen-activated protein kinases in human vascular smooth muscle cells
    • Sakoda M, Ichihara A, Kaneshiro Y, et al. (Pro)renin receptormediated activation of mitogen-activated protein kinases in human vascular smooth muscle cells. Hypertens Res 2007; 30: 1139-46.
    • (2007) Hypertens Res , vol.30 , pp. 1139-1146
    • Sakoda, M.1    Ichihara, A.2    Kaneshiro, Y.3
  • 83
    • 30944469631 scopus 로고    scopus 로고
    • Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms
    • Huang Y, Wongamorntham S, Kasting J, et al. Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms. Kidney Int 2006; 69: 105-13.
    • (2006) Kidney Int , vol.69 , pp. 105-113
    • Huang, Y.1    Wongamorntham, S.2    Kasting, J.3
  • 84
    • 77957334373 scopus 로고    scopus 로고
    • Role of (pro)renin receptor in cardiovascular cells from the aspect of signaling
    • Hitom H, Liu G, Nishiyama A. Role of (pro)renin receptor in cardiovascular cells from the aspect of signaling. Front Biosci 2010; 2:1246-9.
    • (2010) Front Biosci , vol.2 , pp. 1246-1249
    • Hitom, H.1    Liu, G.2    Nishiyama, A.3
  • 85
    • 77649171183 scopus 로고    scopus 로고
    • (Pro)renin receptor contributes to diabetic nephropathy by enhancing renal inflammation
    • Matavelli LC, Huang J, Siragy HM. (Pro)renin receptor contributes to diabetic nephropathy by enhancing renal inflammation. Clin Exp Pharmacol Physiol 2010; 37: 277-82.
    • (2010) Clin Exp Pharmacol Physiol , vol.37 , pp. 277-282
    • Matavelli, L.C.1    Huang, J.2    Siragy, H.M.3
  • 86
    • 33644983896 scopus 로고    scopus 로고
    • Elevated blood pressure and heart rate in human renin receptor transgenic rats
    • Burcklé CA, Jan Danser AH, Müller DN, et al. Elevated blood pressure and heart rate in human renin receptor transgenic rats. Hypertension 2006; 47: 552-6.
    • (2006) Hypertension , vol.47 , pp. 552-556
    • Burcklé, C.A.1    Jan Danser, A.H.2    Müller, D.N.3
  • 87
    • 33747060126 scopus 로고    scopus 로고
    • Increased expression of cyclooxygenase-2 in the renal cortex of human prorenin receptor gene-transgenic rats
    • Kaneshiro Y, Ichihara A, Takemitsu T, et al. Increased expression of cyclooxygenase-2 in the renal cortex of human prorenin receptor gene-transgenic rats. Kidney Int 2006; 70: 641-6.
    • (2006) Kidney Int , vol.70 , pp. 641-646
    • Kaneshiro, Y.1    Ichihara, A.2    Takemitsu, T.3
  • 88
    • 34249881320 scopus 로고    scopus 로고
    • Slowly progressive, angiotensin II-independent glomerulosclerosis in human (pro)renin receptor-transgenic rats
    • Kaneshiro Y, Ichihara A, Sakoda M, et al. Slowly progressive, angiotensin II-independent glomerulosclerosis in human (pro)renin receptor-transgenic rats. J Am Soc Nephrol 2007; 18: 1789-95.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 1789-1795
    • Kaneshiro, Y.1    Ichihara, A.2    Sakoda, M.3
  • 89
    • 60649085140 scopus 로고    scopus 로고
    • Association of (pro)renin receptor gene polymorphism with blood pressure in Japanese men: The Ohasama study
    • Hirose T, Hashimoto M, Totsune K, et al. Association of (pro)renin receptor gene polymorphism with blood pressure in Japanese men: the Ohasama study. Am J Hypertens 2009; 22: 294-9.
    • (2009) Am J Hypertens , vol.22 , pp. 294-299
    • Hirose, T.1    Hashimoto, M.2    Totsune, K.3
  • 90
    • 39749088803 scopus 로고    scopus 로고
    • (Pro)renin receptor peptide inhibitor handle-region peptide does not affect hypertensive nephrosclerosis in Goldblatt rats
    • Muller DN, Klanke B, Feldt S, et al. (Pro)renin receptor peptide inhibitor handle-region peptide does not affect hypertensive nephrosclerosis in Goldblatt rats. Hypertension 2008; 51: 676-81.
    • (2008) Hypertension , vol.51 , pp. 676-681
    • Muller, D.N.1    Klanke, B.2    Feldt, S.3
  • 91
    • 37349054998 scopus 로고    scopus 로고
    • Dose-dependent titration of prorenin and blood pressure in Cyp1a1ren-2 transgenic rats: Absence of prorenin-induced glomerulosclerosis
    • Peters B, Grisk O, Becher B, et al. Dose-dependent titration of prorenin and blood pressure in Cyp1a1ren-2 transgenic rats: absence of prorenin-induced glomerulosclerosis. J Hypertens 2008; 26: 102-9.
    • (2008) J Hypertens , vol.26 , pp. 102-109
    • Peters, B.1    Grisk, O.2    Becher, B.3
  • 92
    • 54049106595 scopus 로고    scopus 로고
    • Cardiovascular effects of prorenin blockade in genetically spontaneously hypertensive rats on normal and high-salt diet
    • Susic D, Zhou X, Frohlich ED, Lippton H, Knight M. Cardiovascular effects of prorenin blockade in genetically spontaneously hypertensive rats on normal and high-salt diet. Am J Physiol Heart Circ Physiol 2008; 295: H1117-H1121.
    • (2008) Am J Physiol Heart Circ Physiol , vol.295
    • Susic, D.1    Zhou, X.2    Frohlich, E.D.3    Lippton, H.4    Knight, M.5
  • 93
    • 46449118638 scopus 로고    scopus 로고
    • Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats
    • Feldman DL, Jin L, Xuan H, et al. Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats. Hypertension 2008; 52: 130-6.
    • (2008) Hypertension , vol.52 , pp. 130-136
    • Feldman, D.L.1    Jin, L.2    Xuan, H.3
  • 95
    • 0036348676 scopus 로고    scopus 로고
    • Effects of enalapril and losartan on circulating adhesion molecules and monocyte chemotactic protein-1
    • Jilma B, Li-Saw-Hee FL, Wagner OF, Beevers DG, Lip GY. Effects of enalapril and losartan on circulating adhesion molecules and monocyte chemotactic protein-1. Clin Sci 2002, 103: 131-6.
    • (2002) Clin Sci , vol.103 , pp. 131-136
    • Jilma, B.1    Li-Saw-Hee, F.L.2    Wagner, O.F.3    Beevers, D.G.4    Lip, G.Y.5
  • 96
    • 2542508394 scopus 로고    scopus 로고
    • Angiotensin II activates the proinflammatory transcription factor nuclear factorkappaB in human monocytes
    • Kranzhöfer R, Browatzki M, Schmidt J, Kübler W. Angiotensin II activates the proinflammatory transcription factor nuclear factorkappaB in human monocytes. Biochem Biophys Res Commun 1999; 257: 826-8.
    • (1999) Biochem Biophys Res Commun , vol.257 , pp. 826-828
    • Kranzhöfer, R.1    Browatzki, M.2    Schmidt, J.3    Kübler, W.4
  • 97
    • 0030950540 scopus 로고    scopus 로고
    • Angiotensinconverting enzyme inhibition prevents arterial nuclear factor-kappa B activation, monocyte chemoattractant protein-1 expression, and macrophage infiltration in a rabbit model of early accelerated atherosclerosis
    • Hernández-Presa M, Bustos C, Ortego M, et al. Angiotensinconverting enzyme inhibition prevents arterial nuclear factor-kappa B activation, monocyte chemoattractant protein-1 expression, and macrophage infiltration in a rabbit model of early accelerated atherosclerosis. Circulation 1997; 95: 1532-41.
    • (1997) Circulation , vol.95 , pp. 1532-1541
    • Hernández-Presa, M.1    Bustos, C.2    Ortego, M.3
  • 99
    • 13344261982 scopus 로고    scopus 로고
    • Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion
    • Brand K, Page S, Rogler G, et al. Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J Clin Invest 1996; 97: 1715-22.
    • (1996) J Clin Invest , vol.97 , pp. 1715-1722
    • Brand, K.1    Page, S.2    Rogler, G.3
  • 100
    • 26244440599 scopus 로고    scopus 로고
    • Complement activation in angiotensin II-induced organ damage
    • Shagdarsuren E, Wellner M, Braesen JH, et al. Complement activation in angiotensin II-induced organ damage. Circ Res 2005; 97: 716-24.
    • (2005) Circ Res , vol.97 , pp. 716-724
    • Shagdarsuren, E.1    Wellner, M.2    Braesen, J.H.3
  • 101
    • 33947427486 scopus 로고    scopus 로고
    • Angiotensin II receptor type 1-mediated vascular oxidative stress and proinflammatory gene expression in aldosterone-induced hypertension: The possible role of local renin-angiotensin system
    • Hirono Y, Yoshimoto T, Suzuki N, et al. Angiotensin II receptor type 1-mediated vascular oxidative stress and proinflammatory gene expression in aldosterone-induced hypertension: the possible role of local renin-angiotensin system. Endocrinology 2007; 148: 1688-96.
    • (2007) Endocrinology , vol.148 , pp. 1688-1696
    • Hirono, Y.1    Yoshimoto, T.2    Suzuki, N.3
  • 102
    • 0033977163 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme expression in human carotid artery atherosclerosis
    • Fukuhara M, Geary RL, Diz DI, et al. Angiotensin-converting enzyme expression in human carotid artery atherosclerosis. Hypertension 2000; 35: 353-9.
    • (2000) Hypertension , vol.35 , pp. 353-359
    • Fukuhara, M.1    Geary, R.L.2    Diz, D.I.3
  • 103
    • 0030659486 scopus 로고    scopus 로고
    • Enhanced expression of angiotensin-converting enzyme is associated with progression of coronary atherosclerosis in humans
    • Ohishi M, Ueda M, Rakugi H, et al. Enhanced expression of angiotensin-converting enzyme is associated with progression of coronary atherosclerosis in humans. J Hypertens 1997; 15: 1295-302.
    • (1997) J Hypertens , vol.15 , pp. 1295-1302
    • Ohishi, M.1    Ueda, M.2    Rakugi, H.3
  • 104
    • 0029009268 scopus 로고
    • Angiotensin II stimulates macrophage-mediated oxidation of low density lipoproteins
    • Keidar S, Kaplan M, Hoffman A, Aviram M. Angiotensin II stimulates macrophage-mediated oxidation of low density lipoproteins. Atherosclerosis 1995; 115: 201-15.
    • (1995) Atherosclerosis , vol.115 , pp. 201-215
    • Keidar, S.1    Kaplan, M.2    Hoffman, A.3    Aviram, M.4
  • 105
    • 0029084524 scopus 로고
    • Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques. Potential role of matrix-degrading metalloproteinases and implications for plaque rupture
    • Shah PK, Falk E, Badimon JJ, et al. Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques. Potential role of matrix-degrading metalloproteinases and implications for plaque rupture. Circulation 1995; 92: 1565-9.
    • (1995) Circulation , vol.92 , pp. 1565-1569
    • Shah, P.K.1    Falk, E.2    Badimon, J.J.3
  • 107
    • 0032825861 scopus 로고    scopus 로고
    • Ramiprilat prevents the development of acute coronary endothelial dysfunction in the dog
    • Martorana PA, Ruetten H, Goebel B, et al. Ramiprilat prevents the development of acute coronary endothelial dysfunction in the dog. Basic Res Cardiol 1999; 94: 238-45.
    • (1999) Basic Res Cardiol , vol.94 , pp. 238-245
    • Martorana, P.A.1    Ruetten, H.2    Goebel, B.3
  • 108
    • 0026334256 scopus 로고
    • Preservation of endothelial function by ramipril in rabbits on a long-term atherogenic diet
    • Becker RH, Wiemer G, Linz W. Preservation of endothelial function by ramipril in rabbits on a long-term atherogenic diet. J Cardiovasc Pharmacol 1991; 18: S110-5.
    • (1991) J Cardiovasc Pharmacol , vol.18
    • Becker, R.H.1    Wiemer, G.2    Linz, W.3
  • 109
    • 0026688284 scopus 로고
    • Trandolapril inhibits atherosclerosis in the Watanabe heritable hyperlipidemic rabbit
    • Chobanian AV, Haudenschild CC, Nickerson C, Hope S. Trandolapril inhibits atherosclerosis in the Watanabe heritable hyperlipidemic rabbit. Hypertension 1992; 20: 473-7.
    • (1992) Hypertension , vol.20 , pp. 473-477
    • Chobanian, A.V.1    Haudenschild, C.C.2    Nickerson, C.3    Hope, S.4
  • 110
    • 0033986442 scopus 로고    scopus 로고
    • Attenuation of atherosclerosis in apolipoprotein E-deficient mice by ramipril is dissociated from its antihypertensive effect and from potentiation of bradykinin
    • Keidar S, Attias J, Coleman R, Wirth K, Schölkens B, Hayek T. Attenuation of atherosclerosis in apolipoprotein E-deficient mice by ramipril is dissociated from its antihypertensive effect and from potentiation of bradykinin. Cardiovasc Pharmacol 2000; 35: 64-72.
    • (2000) Cardiovasc Pharmacol , vol.35 , pp. 64-72
    • Keidar, S.1    Attias, J.2    Coleman, R.3    Wirth, K.4    Schölkens, B.5    Hayek, T.6
  • 111
    • 0032719311 scopus 로고    scopus 로고
    • Anti-atherosclerotic effects of an angiotensin converting enzyme inhibitor and an angiotensin II antagonist in Cynomolgus monkeys fed a high-cholesterol diet
    • Miyazaki M, Sakonjo H, Takai S. Anti-atherosclerotic effects of an angiotensin converting enzyme inhibitor and an angiotensin II antagonist in Cynomolgus monkeys fed a high-cholesterol diet. Br J Pharmacol 1999; 128: 523-9.
    • (1999) Br J Pharmacol , vol.128 , pp. 523-529
    • Miyazaki, M.1    Sakonjo, H.2    Takai, S.3
  • 112
    • 0035916235 scopus 로고    scopus 로고
    • Effects of ramipril and vitamin E on atherosclerosis: The study to evaluate carotid ultrasound changes in patients treated with ramipril and vitamin E (SECURE)
    • Lonn E, Yusuf S, Dzavik V, et al. Effects of ramipril and vitamin E on atherosclerosis: the study to evaluate carotid ultrasound changes in patients treated with ramipril and vitamin E (SECURE). Circulation 2001; 103: 919-25.
    • (2001) Circulation , vol.103 , pp. 919-925
    • Lonn, E.1    Yusuf, S.2    Dzavik, V.3
  • 113
    • 0033860871 scopus 로고    scopus 로고
    • Randomized, placebocontrolled trial of the angiotensin-converting enzyme inhibitor, ramipril, in patients with coronary or other occlusive arterial disease. PART-2 Collaborative Research Group. Prevention of Atherosclerosis with Ramipril
    • MacMahon S, Sharpe N, Gamble G, et al. Randomized, placebocontrolled trial of the angiotensin-converting enzyme inhibitor, ramipril, in patients with coronary or other occlusive arterial disease. PART-2 Collaborative Research Group. Prevention of Atherosclerosis with Ramipril. J Am Coll Cardiol 2000; 36: 438-43.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 438-443
    • Macmahon, S.1    Sharpe, N.2    Gamble, G.3
  • 114
    • 0034633814 scopus 로고    scopus 로고
    • Long-term effects of cholesterol lowering and angiotensin-converting enzyme inhibition on coronary atherosclerosis: The Simvastatin/Enalapril Coronary Atherosclerosis Trial (SCAT)
    • Teo KK, Burton JR, Buller CE, et al. Long-term effects of cholesterol lowering and angiotensin-converting enzyme inhibition on coronary atherosclerosis: The Simvastatin/Enalapril Coronary Atherosclerosis Trial (SCAT). Circulation 2000; 102: 1748-54.
    • (2000) Circulation , vol.102 , pp. 1748-1754
    • Teo, K.K.1    Burton, J.R.2    Buller, C.E.3
  • 115
    • 7744231805 scopus 로고    scopus 로고
    • Effect of antihypertensive agents on cardiovascular events in patients with coronary disease and normal blood pressure: The CAMELOT study: A randomized controlled trial
    • Nissen SE, Tuzcu EM, Libby P, et al. Effect of antihypertensive agents on cardiovascular events in patients with coronary disease and normal blood pressure: the CAMELOT study: a randomized controlled trial. JAMA 2004; 292: 2217-25.
    • (2004) JAMA , vol.292 , pp. 2217-2225
    • Nissen, S.E.1    Tuzcu, E.M.2    Libby, P.3
  • 116
    • 0035838416 scopus 로고    scopus 로고
    • Prognostic significance of endothelial dysfunction in hypertensive patients
    • Perticone F, Ceravolo R, Pujia A, et al. Prognostic significance of endothelial dysfunction in hypertensive patients. Circulation 2001; 104: 191-6.
    • (2001) Circulation , vol.104 , pp. 191-196
    • Perticone, F.1    Ceravolo, R.2    Pujia, A.3
  • 117
    • 0033966627 scopus 로고    scopus 로고
    • Comparative study of ACEinhibition, angiotensin II antagonism, and calcium channel blockade on flow-mediated vasodilation in patients with coronary disease (BANFF study)
    • Baldasseroni S, Urso R, Orso F, et al. Comparative study of ACEinhibition, angiotensin II antagonism, and calcium channel blockade on flow-mediated vasodilation in patients with coronary disease (BANFF study). J Am Coll Cardiol 2000; 35: 60-6.
    • (2000) J Am Coll Cardiol , vol.35 , pp. 60-66
    • Baldasseroni, S.1    Urso, R.2    Orso, F.3
  • 118
    • 0042878465 scopus 로고    scopus 로고
    • Pleiotropic effects of angiotensin II receptor blocker in hypertensive patients
    • Koh KK, Ahn JY, Han SH, et al. Pleiotropic effects of angiotensin II receptor blocker in hypertensive patients. J Am Coll Cardiol 2003; 42: 905-10.
    • (2003) J Am Coll Cardiol , vol.42 , pp. 905-910
    • Koh, K.K.1    Ahn, J.Y.2    Han, S.H.3
  • 119
    • 9444280103 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition with quinapril improves endothelial vasomotor dysfunction in patients with coronary artery disease. The TREND (Trial on Reversing ENdothelial Dysfunction) Study
    • Mancini GB, Henry GC, Macaya C, et al. Angiotensin-converting enzyme inhibition with quinapril improves endothelial vasomotor dysfunction in patients with coronary artery disease. The TREND (Trial on Reversing ENdothelial Dysfunction) Study. Circulation 1996; 94: 258-65.
    • (1996) Circulation , vol.94 , pp. 258-265
    • Mancini, G.B.1    Henry, G.C.2    Macaya, C.3
  • 120
    • 0035852775 scopus 로고    scopus 로고
    • Comparative effect of ace inhibition and angiotensin II type 1 receptor antagonism on bioavailability of nitric oxide in patients with coronary artery disease: Role of superoxide dismutase
    • Hornig B, Landmesser U, Kohler C, et al. Comparative effect of ace inhibition and angiotensin II type 1 receptor antagonism on bioavailability of nitric oxide in patients with coronary artery disease: role of superoxide dismutase. Circulation 2001; 103: 799-805.
    • (2001) Circulation , vol.103 , pp. 799-805
    • Hornig, B.1    Landmesser, U.2    Kohler, C.3
  • 121
    • 3242720779 scopus 로고    scopus 로고
    • Comparative effects of AT1-antagonism and angiotensin-converting enzyme inhibition on markers of inflammation and platelet aggregation in patients with coronary artery disease
    • Schieffer B, Bünte C, Witte J, et al. Comparative effects of AT1-antagonism and angiotensin-converting enzyme inhibition on markers of inflammation and platelet aggregation in patients with coronary artery disease. J Am Coll Cardiol 2004; 44: 362-8.
    • (2004) J Am Coll Cardiol , vol.44 , pp. 362-368
    • Schieffer, B.1    Bünte, C.2    Witte, J.3
  • 122
    • 0345599227 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitor use is associated with reduced plasma concentration of C-reactive protein in patients with first-ever ischemic stroke
    • Di Napoli M, Papa F. Angiotensin-converting enzyme inhibitor use is associated with reduced plasma concentration of C-reactive protein in patients with first-ever ischemic stroke. Stroke 2003; 34: 2922-9.
    • (2003) Stroke , vol.34 , pp. 2922-2929
    • Di Napoli, M.1    Papa, F.2
  • 123
    • 4844231461 scopus 로고    scopus 로고
    • EUropean Trial on Olmesartan and Pravastatin in Inflammation and Atherosclerosis (EUTOPIA) Investigators. Antiinflammatory effects of angiotensin II subtype 1 receptor blockade in hypertensive patients with microinflammation
    • Fliser D, Buchholz K, Haller H; EUropean Trial on Olmesartan and Pravastatin in Inflammation and Atherosclerosis (EUTOPIA) Investigators. Antiinflammatory effects of angiotensin II subtype 1 receptor blockade in hypertensive patients with microinflammation. Circulation 2004, 110: 1103-7.
    • (2004) Circulation , vol.110 , pp. 1103-1107
    • Fliser, D.1    Buchholz, K.2    Haller, H.3
  • 124
    • 4444268576 scopus 로고    scopus 로고
    • Effect of enalapril and losartan on cytokines in patients with stable angina pectoris awaiting coronary artery bypass grafting and their interaction with polymorphisms in the interleukin-6 gene
    • Trevelyan J, Brull DJ, Needham EW, Montgomery HE, Morris A, Mattu RK. Effect of enalapril and losartan on cytokines in patients with stable angina pectoris awaiting coronary artery bypass grafting and their interaction with polymorphisms in the interleukin-6 gene. Am J Cardiol 2004; 94: 564-9.
    • (2004) Am J Cardiol , vol.94 , pp. 564-569
    • Trevelyan, J.1    Brull, D.J.2    Needham, E.W.3    Montgomery, H.E.4    Morris, A.5    Mattu, R.K.6
  • 125
    • 3042797776 scopus 로고    scopus 로고
    • Exploring the effects of ACE inhibitor tissue penetration on vascular inflammation following acute myocardial infarction
    • Tsikouris JP, Suarez JA, Simoni JS, Ziska M, Meyerrose GE. Exploring the effects of ACE inhibitor tissue penetration on vascular inflammation following acute myocardial infarction. Coron Artery Dis 2004; 15: 211-7.
    • (2004) Coron Artery Dis , vol.15 , pp. 211-217
    • Tsikouris, J.P.1    Suarez, J.A.2    Simoni, J.S.3    Ziska, M.4    Meyerrose, G.E.5
  • 126
    • 0038476580 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor antagonists inhibit basal as well as low-density lipoprotein and platelet-activating factor-stimulated human monocyte chemoattractant protein-1
    • Proudfoot JM, Croft KD, Puddey IB, Beilin LJ. Angiotensin II type 1 receptor antagonists inhibit basal as well as low-density lipoprotein and platelet-activating factor-stimulated human monocyte chemoattractant protein-1. J Pharmacol Exp Ther 2003; 305: 846-53.
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 846-853
    • Proudfoot, J.M.1    Croft, K.D.2    Puddey, I.B.3    Beilin, L.J.4
  • 127
    • 0037426399 scopus 로고    scopus 로고
    • C-reactive protein upregulates angiotensin type 1 receptors in vascular smooth muscle
    • Wang CH, Li SH, Weisel RD, et al. C-reactive protein upregulates angiotensin type 1 receptors in vascular smooth muscle. Circulation 2003; 107: 1783-90.
    • (2003) Circulation , vol.107 , pp. 1783-1790
    • Wang, C.H.1    Li, S.H.2    Weisel, R.D.3
  • 128
    • 68949166336 scopus 로고    scopus 로고
    • Renin inhibition--benefit beyond hypertension control
    • Kher V. Renin inhibition--benefit beyond hypertension control. J Assoc Physicians India 2009; 57: 518-20, 525.
    • (2009) J Assoc Physicians India , vol.57
    • Kher, V.1
  • 129
    • 77249114746 scopus 로고    scopus 로고
    • Pleiotropic effects of inhibitors of the RAAS in the diabetic population: Above and beyond blood pressure lowering
    • Ismail H, Mitchell R, McFarlane SI, Makaryus AN. Pleiotropic effects of inhibitors of the RAAS in the diabetic population: above and beyond blood pressure lowering. Curr Diab Rep 2010; 10: 32-6.
    • (2010) Curr Diab Rep , vol.10 , pp. 32-36
    • Ismail, H.1    Mitchell, R.2    McFarlane, S.I.3    Makaryus, A.N.4
  • 130
    • 64949190067 scopus 로고    scopus 로고
    • Blood pressure reduction and renin-angiotensin system inhibition for prevention of congestive heart failure: A meta-analysis
    • Verdecchia P, Angeli F, Cavallini C, et al. Blood pressure reduction and renin-angiotensin system inhibition for prevention of congestive heart failure: a meta-analysis. Eur Heart J 2009; 30: 679-88.
    • (2009) Eur Heart J , vol.30 , pp. 679-688
    • Verdecchia, P.1    Angeli, F.2    Cavallini, C.3
  • 131
    • 0036111215 scopus 로고    scopus 로고
    • Anti-atherosclerotic efficacy of olmesartan
    • Miyazaki M, Takai S. Anti-atherosclerotic efficacy of olmesartan. J Hum Hypertens 2002; 16: S7-12.
    • (2002) J Hum Hypertens , vol.16
    • Miyazaki, M.1    Takai, S.2
  • 132
    • 0034603775 scopus 로고    scopus 로고
    • Inhibition of early atherogenesis by losartan in monkeys with dietinduced hypercholesterolemia
    • Strawn WB, Chappell MC, Dean RH, Kivlighn S, Ferrario CM. Inhibition of early atherogenesis by losartan in monkeys with dietinduced hypercholesterolemia. Circulation 2000; 101: 1586-93.
    • (2000) Circulation , vol.101 , pp. 1586-1593
    • Strawn, W.B.1    Chappell, M.C.2    Dean, R.H.3    Kivlighn, S.4    Ferrario, C.M.5
  • 133
    • 35848957040 scopus 로고    scopus 로고
    • Olmesartan and pravastatin additively reduce development of atherosclerosis in APOE*3Leiden transgenic mice
    • van der Hoorn JW, Kleemann R, Havekes LM, Kooistra T, Princen HM, Jukema JW. Olmesartan and pravastatin additively reduce development of atherosclerosis in APOE*3Leiden transgenic mice. J Hypertens 2007; 25: 2454-62.
    • (2007) J Hypertens , vol.25 , pp. 2454-2462
    • van der Hoorn, J.W.1    Kleemann, R.2    Havekes, L.M.3    Kooistra, T.4    Princen, H.M.5    Jukema, J.W.6
  • 134
    • 77749298626 scopus 로고    scopus 로고
    • Crucial role of renin-angiotensin system in the pathogenesis of atherosclerosis
    • Sata M, Fukuda D. Crucial role of renin-angiotensin system in the pathogenesis of atherosclerosis. J Med Invest 2010; 57: 12-25.
    • (2010) J Med Invest , vol.57 , pp. 12-25
    • Sata, M.1    Fukuda, D.2
  • 135
    • 0034636121 scopus 로고    scopus 로고
    • Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan
    • Schiffrin EL, Park JB, Intengan HD, Touyz RM. Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan. Circulation 2000; 101: 1653-9.
    • (2000) Circulation , vol.101 , pp. 1653-1659
    • Schiffrin, E.L.1    Park, J.B.2    Intengan, H.D.3    Touyz, R.M.4
  • 136
    • 0034682662 scopus 로고    scopus 로고
    • Improvement of endothelial function by chronic angiotensin-converting enzyme inhibition in heart failure: Role of nitric oxide, prostanoids, oxidant stress, and bradykinin
    • Varin R, Mulder P, Tamion F, et al. Improvement of endothelial function by chronic angiotensin-converting enzyme inhibition in heart failure: role of nitric oxide, prostanoids, oxidant stress, and bradykinin. Circulation 2000; 102: 351-6.
    • (2000) Circulation , vol.102 , pp. 351-356
    • Varin, R.1    Mulder, P.2    Tamion, F.3
  • 137
    • 0036347258 scopus 로고    scopus 로고
    • Eledrisi MS.Vascular inflammation and the renin-angiotensin system
    • Brasier AR, Recinos A 3rd, Eledrisi MS.Vascular inflammation and the renin-angiotensin system. Arterioscler Thromb Vasc Biol 2002; 22: 1257-66.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1257-1266
    • Brasier, A.R.1    Recinos 3rd, A.2
  • 138
  • 140
    • 37549004727 scopus 로고    scopus 로고
    • Critical role of bone marrow angiotensin II type 1 receptor in the pathogenesis of atherosclerosis in apolipoprotein E deficient mice
    • Fukuda D, Sata M, Ishizaka N, Nagai R. Critical role of bone marrow angiotensin II type 1 receptor in the pathogenesis of atherosclerosis in apolipoprotein E deficient mice. Arterioscler Thromb Vasc Biol 2008; 28: 90-6.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 90-96
    • Fukuda, D.1    Sata, M.2    Ishizaka, N.3    Nagai, R.4
  • 141
    • 43049168749 scopus 로고    scopus 로고
    • Role of bone marrow renin-angiotensin system in the pathogenesis of atherosclerosis
    • Fukuda D, Sata M. Role of bone marrow renin-angiotensin system in the pathogenesis of atherosclerosis. Pharmacol Ther 2008; 118: 268-76.
    • (2008) Pharmacol Ther , vol.118 , pp. 268-276
    • Fukuda, D.1    Sata, M.2
  • 142
    • 0034677947 scopus 로고    scopus 로고
    • NAD(P)H oxidase: Role in cardiovascular biology and disease
    • Griendling KK, Sorescu D, Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res 2000, 86: 494-501.
    • (2000) Circ Res , vol.86 , pp. 494-501
    • Griendling, K.K.1    Sorescu, D.2    Ushio-Fukai, M.3
  • 143
    • 0035179016 scopus 로고    scopus 로고
    • p47phox is required for atherosclerotic lesion progression in ApoE(-/-) mice
    • Barry-Lane PA, Patterson C, van der Merwe M, et al. p47phox is required for atherosclerotic lesion progression in ApoE(-/-) mice. J Clin Invest 2001; 108: 1513-22.
    • (2001) J Clin Invest , vol.108 , pp. 1513-1522
    • Barry-Lane, P.A.1    Patterson, C.2    van der Merwe, M.3
  • 144
    • 0034090421 scopus 로고    scopus 로고
    • Differential activation of mitogen-activated protein kinases in smooth muscle cells by angiotensin II: Involvement of p22phox and reactive oxygen species
    • Viedt C, Soto U, Krieger-Brauer HI, et al. Differential activation of mitogen-activated protein kinases in smooth muscle cells by angiotensin II: involvement of p22phox and reactive oxygen species. Arterioscler Thromb Vasc Biol 2000; 20: 940-8.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 940-948
    • Viedt, C.1    Soto, U.2    Krieger-Brauer, H.I.3
  • 145
    • 0033529675 scopus 로고    scopus 로고
    • Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells
    • Ushio-Fukai M, Alexander RW, Akers M, et al. Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells. J Biol Chem 1999; 274: 22699-704.
    • (1999) J Biol Chem , vol.274 , pp. 22699-2704
    • Ushio-Fukai, M.1    Alexander, R.W.2    Akers, M.3
  • 147
    • 0035048905 scopus 로고    scopus 로고
    • Theodore Cooper Lecture: Tissue angiotensin and pathobiology of vascular disease: A unifying hypothesis
    • Dzau VJ. Theodore Cooper Lecture: Tissue angiotensin and pathobiology of vascular disease: a unifying hypothesis. Hypertension 2001; 37: 1047-52.
    • (2001) Hypertension , vol.37 , pp. 1047-1052
    • Dzau, V.J.1
  • 148
    • 0033586639 scopus 로고    scopus 로고
    • Increased NADHoxidase-mediated superoxide production in the early stages of atherosclerosis: Evidence for involvement of the renin-angiotensin system
    • Warnholtz A, Nickenig G, Schulz E, et al. Increased NADHoxidase-mediated superoxide production in the early stages of atherosclerosis: evidence for involvement of the renin-angiotensin system. Circulation 1999; 99: 2027-33.
    • (1999) Circulation , vol.99 , pp. 2027-2033
    • Warnholtz, A.1    Nickenig, G.2    Schulz, E.3
  • 149
    • 0028365310 scopus 로고
    • Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
    • Griendling KK, Minieri CA, Ollerenshaw JD, Alexander RW. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res 1994; 74: 1141-8.
    • (1994) Circ Res , vol.74 , pp. 1141-1148
    • Griendling, K.K.1    Minieri, C.A.2    Ollerenshaw, J.D.3    Alexander, R.W.4
  • 150
    • 0029101772 scopus 로고
    • Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers
    • Collins T, Read MA, Neish AS, Whitley MZ, Thanos D, Maniatis T. Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers. FASEB J 1995; 9: 899-909.
    • (1995) FASEB J , vol.9 , pp. 899-909
    • Collins, T.1    Read, M.A.2    Neish, A.S.3    Whitley, M.Z.4    Thanos, D.5    Maniatis, T.6
  • 151
    • 34948822892 scopus 로고    scopus 로고
    • Proinflammatory cytokines increase reactive oxygen species through mitochondria and NADPH oxidase in cultured RPE cells
    • Yang D, Elner SG, Bian ZM, Till GO, Petty HR, Elner VM. Proinflammatory cytokines increase reactive oxygen species through mitochondria and NADPH oxidase in cultured RPE cells. Exp Eye Res 2007, 85: 462-72.
    • (2007) Exp Eye Res , vol.85 , pp. 462-472
    • Yang, D.1    Elner, S.G.2    Bian, Z.M.3    Till, G.O.4    Petty, H.R.5    Elner, V.M.6
  • 152
    • 0028300301 scopus 로고
    • The emerging concept of vascular remodeling
    • Gibbons GH, Dzau VJ.The emerging concept of vascular remodeling. N Engl J Med 1994; 330: 1431-8.
    • (1994) N Engl J Med , vol.330 , pp. 1431-1438
    • Gibbons, G.H.1    Dzau, V.J.2
  • 153
    • 79251493807 scopus 로고    scopus 로고
    • Endothelial dysfunction: Potential clinical implications
    • Tousoulis D, Koutsogiannis M, Papageorgiou N, et al. Endothelial dysfunction: potential clinical implications. Minerva Med 2010; 101: 271-84.
    • (2010) Minerva Med , vol.101 , pp. 271-284
    • Tousoulis, D.1    Koutsogiannis, M.2    Papageorgiou, N.3
  • 154
    • 0028821016 scopus 로고
    • Theodore Cooper Memorial Lecture. Hypertension and the pathogenesis of atherosclerosis. Oxidative stress and the mediation of arterial inflammatory response: A new perspective
    • Alexander RW. Theodore Cooper Memorial Lecture. Hypertension and the pathogenesis of atherosclerosis. Oxidative stress and the mediation of arterial inflammatory response: a new perspective. Hypertension 1995; 25: 155-61.
    • (1995) Hypertension , vol.25 , pp. 155-161
    • Alexander, R.W.1
  • 155
    • 0029111432 scopus 로고
    • Nitric oxide inhibits angiotensin II-induced migration of rat aortic smooth muscle cell. Role of cyclic-nucleotides and angiotensin1 receptors
    • Dubey RK, Jackson EK, Lüscher TF. Nitric oxide inhibits angiotensin II-induced migration of rat aortic smooth muscle cell. Role of cyclic-nucleotides and angiotensin1 receptors. J Clin Invest 1995; 96: 141-9.
    • (1995) J Clin Invest , vol.96 , pp. 141-149
    • Dubey, R.K.1    Jackson, E.K.2    Lüscher, T.F.3
  • 156
    • 0029011129 scopus 로고
    • Induction and stabilization of I kappa B alpha by nitric oxide mediates inhibition of NF-kappa B
    • Peng HB, Libby P, Liao JK. Induction and stabilization of I kappa B alpha by nitric oxide mediates inhibition of NF-kappa B. J Biol Chem 1995; 270: 14214-9.
    • (1995) J Biol Chem , vol.270 , pp. 14214-14219
    • Peng, H.B.1    Libby, P.2    Liao, J.K.3
  • 157
    • 0029159779 scopus 로고
    • Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines
    • De Caterina R, Libby P, Peng HB, et al. Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J Clin Invest 1995; 96: 60-8.
    • (1995) J Clin Invest , vol.96 , pp. 60-68
    • de Caterina, R.1    Libby, P.2    Peng, H.B.3
  • 158
    • 0033515524 scopus 로고    scopus 로고
    • Angiotensin II induces interleukin-6 transcription in vascular smooth muscle cells through pleiotropic activation of nuclear factor-kappa B transcription factors
    • Han Y, Runge MS, Brasier AR. Angiotensin II induces interleukin-6 transcription in vascular smooth muscle cells through pleiotropic activation of nuclear factor-kappa B transcription factors. Circ Res 1999; 84: 695-703.
    • (1999) Circ Res , vol.84 , pp. 695-703
    • Han, Y.1    Runge, M.S.2    Brasier, A.R.3
  • 159
    • 0028304231 scopus 로고
    • Activation of human peripheral monocytes by angiotensin II
    • Hahn AW, Jonas U, Bühler FR, Resink TJ. Activation of human peripheral monocytes by angiotensin II. FEBS Lett 1994; 347: 178-80.
    • (1994) FEBS Lett , vol.347 , pp. 178-180
    • Hahn, A.W.1    Jonas, U.2    Bühler, F.R.3    Resink, T.J.4
  • 160
    • 0029820256 scopus 로고    scopus 로고
    • Vasoactive substances regulate vascular smooth muscle cell apoptosis. Countervailing influences of nitric oxide and angiotensin II
    • Pollman MJ, Yamada T, Horiuchi M, Gibbons GH. Vasoactive substances regulate vascular smooth muscle cell apoptosis. Countervailing influences of nitric oxide and angiotensin II. Circ Res 1996; 79: 748-56.
    • (1996) Circ Res , vol.79 , pp. 748-756
    • Pollman, M.J.1    Yamada, T.2    Horiuchi, M.3    Gibbons, G.H.4
  • 161
    • 0029554443 scopus 로고
    • Effect of angiotensin II and thromboxane A2 on the production of matrix metalloproteinase by human aortic smooth muscle cells
    • Takagishi T, Murahashi N, Azagami S, Morimatsu M, Sasaguri Y. Effect of angiotensin II and thromboxane A2 on the production of matrix metalloproteinase by human aortic smooth muscle cells. Biochem Mol Biol Int 1995; 35: 265-73.
    • (1995) Biochem Mol Biol Int , vol.35 , pp. 265-273
    • Takagishi, T.1    Murahashi, N.2    Azagami, S.3    Morimatsu, M.4    Sasaguri, Y.5
  • 162
    • 0026366142 scopus 로고
    • Angiotensin II induction of smooth muscle matrix synthesis in culture
    • Scott-Burden ST, Mackie EJ, Buhler FR. Angiotensin II induction of smooth muscle matrix synthesis in culture. J Vasc Med Biol 1991; 3: 271-276.
    • (1991) J Vasc Med Biol , vol.3 , pp. 271-276
    • Scott-Burden, S.T.1    Mackie, E.J.2    Buhler, F.R.3
  • 163
    • 0024547737 scopus 로고
    • Induction of platelet-derived growth factor A-chain and c-myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells
    • Naftilan AJ, Pratt RE, Dzau VJ. Induction of platelet-derived growth factor A-chain and c-myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells. J Clin Invest 1989; 83: 1419-24.
    • (1989) J Clin Invest , vol.83 , pp. 1419-1424
    • Naftilan, A.J.1    Pratt, R.E.2    Dzau, V.J.3
  • 164
    • 0027160183 scopus 로고
    • Multiple autocrine growth factors modulate vascular smooth muscle cell growth response to angiotensin II
    • Itoh H, Mukoyama M, Pratt RE, Gibbons GH, Dzau VJ. Multiple autocrine growth factors modulate vascular smooth muscle cell growth response to angiotensin II. J Clin Invest 1993; 91: 2268-74.
    • (1993) J Clin Invest , vol.91 , pp. 2268-2274
    • Itoh, H.1    Mukoyama, M.2    Pratt, R.E.3    Gibbons, G.H.4    Dzau, V.J.5
  • 165
    • 0028912882 scopus 로고
    • regulates the expression of plasminogen activator inhibitor-1 in cultured endothelial cells. A potential link between the renin-angiotensin system and thrombosis
    • Vaughan DE, Lazos SA, Tong K. Angiotensin II regulates the expression of plasminogen activator inhibitor-1 in cultured endothelial cells. A potential link between the renin-angiotensin system and thrombosis. J Clin Invest 1995; 95: 995-1001.
    • (1995) J Clin Invest , vol.95 , pp. 995-1001
    • Vaughan, D.E.1    Lazos, S.A.2    Tong, K.3    Angiotensin, I.I.4
  • 166
    • 0027267328 scopus 로고
    • Stimulation of plasminogen activator inhibitor in vivo by infusion of angiotensin II.Evidence of a potential interaction between the renin-angiotensin system and fibrinolytic function
    • Ridker PM, Gaboury CL, Conlin PR, Seely EW, Williams GH, Vaughan DE. Stimulation of plasminogen activator inhibitor in vivo by infusion of angiotensin II.Evidence of a potential interaction between the renin-angiotensin system and fibrinolytic function. Circulation 1993; 87: 1969-73.
    • (1993) Circulation , vol.87 , pp. 1969-1973
    • Ridker, P.M.1    Gaboury, C.L.2    Conlin, P.R.3    Seely, E.W.4    Williams, G.H.5    Vaughan, D.E.6
  • 167
    • 0028802190 scopus 로고
    • Angiotensin induction of PAI-1 expression in endothelial cells is mediated by the hexapeptide angiotensin IV
    • Kerins DM, Hao Q, Vaughan DE. Angiotensin induction of PAI-1 expression in endothelial cells is mediated by the hexapeptide angiotensin IV. J Clin Invest 1995; 96: 2515-20.
    • (1995) J Clin Invest , vol.96 , pp. 2515-2520
    • Kerins, D.M.1    Hao, Q.2    Vaughan, D.E.3
  • 168
    • 0028332718 scopus 로고
    • Angiotensin II increases plasminogen activator inhibitor type 1 and tissue-type plasminogen activator messenger RNA in cultured rat aortic smooth muscle cells
    • van Leeuwen RT, Kol A, Andreotti F, Kluft C, Maseri A, Sperti G. Angiotensin II increases plasminogen activator inhibitor type 1 and tissue-type plasminogen activator messenger RNA in cultured rat aortic smooth muscle cells. Circulation 1994; 90: 362-8.
    • (1994) Circulation , vol.90 , pp. 362-368
    • van Leeuwen, R.T.1    Kol, A.2    Andreotti, F.3    Kluft, C.4    Maseri, A.5    Sperti, G.6
  • 169
    • 0031049715 scopus 로고    scopus 로고
    • Modulation of plasminogen activator inhibitor-1 in vivo: A new mechanism for the anti-fibrotic effect of renin-angiotensin inhibition
    • Oikawa T, Freeman M, Lo W, Vaughan DE, Fogo A. Modulation of plasminogen activator inhibitor-1 in vivo: a new mechanism for the anti-fibrotic effect of renin-angiotensin inhibition. Kidney Int 1997; 51: 164-72.
    • (1997) Kidney Int , vol.51 , pp. 164-172
    • Oikawa, T.1    Freeman, M.2    Lo, W.3    Vaughan, D.E.4    Fogo, A.5
  • 170
    • 0028144267 scopus 로고
    • Induction of angiotensin converting enzyme in the neointima after vascular injury.Possible role in restenosis
    • Rakugi H, Kim DK, Krieger JE, Wang DS, Dzau VJ, Pratt RE. Induction of angiotensin converting enzyme in the neointima after vascular injury.Possible role in restenosis. J Clin Invest 1994; 93: 339-46.
    • (1994) J Clin Invest , vol.93 , pp. 339-346
    • Rakugi, H.1    Kim, D.K.2    Krieger, J.E.3    Wang, D.S.4    Dzau, V.J.5    Pratt, R.E.6
  • 171
    • 0028272442 scopus 로고
    • Potential importance of tissue angiotensin-converting enzyme inhibition in preventing neointima formation
    • Rakugi H, Wang DS, Dzau VJ, Pratt RE. Potential importance of tissue angiotensin-converting enzyme inhibition in preventing neointima formation. Circulation. 1994; 90: 449-55.
    • (1994) Circulation , vol.90 , pp. 449-455
    • Rakugi, H.1    Wang, D.S.2    Dzau, V.J.3    Pratt, R.E.4
  • 172
    • 0029823037 scopus 로고    scopus 로고
    • Increased accumulation of tissue ACE in human atherosclerotic coronary artery disease
    • Diet F, Pratt RE, Berry GJ, Momose N, Gibbons GH, Dzau VJ. Increased accumulation of tissue ACE in human atherosclerotic coronary artery disease. Circulation 1996; 94: 2756-67.
    • (1996) Circulation , vol.94 , pp. 2756-2767
    • Diet, F.1    Pratt, R.E.2    Berry, G.J.3    Momose, N.4    Gibbons, G.H.5    Dzau, V.J.6
  • 174
    • 0021984554 scopus 로고
    • Chemistry of a human monocyte-derived cell line (U937): Identification of the angiotensin I-converting activity as leukocyte cathepsin G
    • Snyder RA, Kaempfer CE, Wintroub BU. Chemistry of a human monocyte-derived cell line (U937): identification of the angiotensin I-converting activity as leukocyte cathepsin G. Blood 1985, 65: 176-82.
    • (1985) Blood , vol.65 , pp. 176-182
    • Snyder, R.A.1    Kaempfer, C.E.2    Wintroub, B.U.3
  • 175
    • 0025937755 scopus 로고
    • Multiple determinants for the high substrate specificity of an angiotensin II-forming chymase from the human heart
    • Kinoshita A, Urata H, Bumpus FM, Husain A. Multiple determinants for the high substrate specificity of an angiotensin II-forming chymase from the human heart. J Biol Chem 1991; 266: 19192-7.
    • (1991) J Biol Chem , vol.266 , pp. 19192-19197
    • Kinoshita, A.1    Urata, H.2    Bumpus, F.M.3    Husain, A.4
  • 176
    • 0033735548 scopus 로고    scopus 로고
    • Angiotensin II induces nuclear factor-kappa B activation in cultured neonatal rat cardiomyocytes through protein kinase C signaling pathway
    • Rouet-Benzineb P, Gontero B, Dreyfus P, Lafuma C. Angiotensin II induces nuclear factor-kappa B activation in cultured neonatal rat cardiomyocytes through protein kinase C signaling pathway. J Mol Cell Cardiol 2000; 32: 1767-78.
    • (2000) J Mol Cell Cardiol , vol.32 , pp. 1767-1778
    • Rouet-Benzineb, P.1    Gontero, B.2    Dreyfus, P.3    Lafuma, C.4
  • 177
    • 0029835633 scopus 로고    scopus 로고
    • Circumferential stress and matrix metalloproteinase 1 in human coronary atherosclerosis. Implications for plaque rupture
    • Lee RT, Schoen FJ, Loree HM, Lark MW, Libby P. Circumferential stress and matrix metalloproteinase 1 in human coronary atherosclerosis. Implications for plaque rupture. Arterioscler Thromb Vasc Biol 1996; 16: 1070-3.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 1070-1073
    • Lee, R.T.1    Schoen, F.J.2    Loree, H.M.3    Lark, M.W.4    Libby, P.5
  • 178
    • 0033977163 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme expression in human carotid artery atherosclerosis
    • Fukuhara M, Geary RL, Diz DI, et al. Angiotensin-converting enzyme expression in human carotid artery atherosclerosis. Hypertension 2000; 35: 353-9.
    • (2000) Hypertension , vol.35 , pp. 353-359
    • Fukuhara, M.1    Geary, R.L.2    Diz, D.I.3
  • 179
    • 0030963869 scopus 로고    scopus 로고
    • Histologic alterations in dermal repair after thermal injury effects of topical angiotensin II
    • Rodgers KE, DeCherney AH, St Amand KM, et al. Histologic alterations in dermal repair after thermal injury effects of topical angiotensin II. J Burn Care Rehabil 1997, 18: 381-8.
    • (1997) J Burn Care Rehabil , vol.18 , pp. 381-388
    • Rodgers, K.E.1    Decherney, A.H.2    St Amand, K.M.3
  • 180
    • 0030659486 scopus 로고    scopus 로고
    • Enhanced expression of angiotensin-converting enzyme is associated with progression of coronary atherosclerosis in humans
    • Ohishi M, Ueda M, Rakugi H, et al. Enhanced expression of angiotensin-converting enzyme is associated with progression of coronary atherosclerosis in humans. J Hypertens 1997, 15: 1295-302.
    • (1997) J Hypertens , vol.15 , pp. 1295-1302
    • Ohishi, M.1    Ueda, M.2    Rakugi, H.3
  • 181
    • 0035814784 scopus 로고    scopus 로고
    • Increased angiotensinconverting enzyme activity in coronary artery specimens from patients with acute coronary syndrome
    • Hoshida S, Kato J, Nishino M, et al. Increased angiotensinconverting enzyme activity in coronary artery specimens from patients with acute coronary syndrome. Circulation 2001; 103: 630-3.
    • (2001) Circulation , vol.103 , pp. 630-633
    • Hoshida, S.1    Kato, J.2    Nishino, M.3
  • 182
    • 0026581772 scopus 로고
    • Angiotensin II-induced mitogenesis of spontaneously hypertensive rat-derived cultured smooth muscle cells is dependent on autocrine production of transforming growth factor-beta
    • Stouffer GA, Owens GK. Angiotensin II-induced mitogenesis of spontaneously hypertensive rat-derived cultured smooth muscle cells is dependent on autocrine production of transforming growth factor-beta. Circ Res 1992; 70: 820-8.
    • (1992) Circ Res , vol.70 , pp. 820-828
    • Stouffer, G.A.1    Owens, G.K.2
  • 185
    • 1542411718 scopus 로고    scopus 로고
    • Angiotensin II potentiates vascular endothelial growth factor-induced proliferation and network formation of endothelial progenitor cells
    • Imanishi T, Hano T, Nishio I. Angiotensin II potentiates vascular endothelial growth factor-induced proliferation and network formation of endothelial progenitor cells. Hypertens Res 2004; 27: 101-8.
    • (2004) Hypertens Res , vol.27 , pp. 101-108
    • Imanishi, T.1    Hano, T.2    Nishio, I.3
  • 186
    • 37849003822 scopus 로고    scopus 로고
    • The renin-Angiotensin system: A potential modulator of endothelial progenitor cells
    • Fukuda D, Sata M. The renin-Angiotensin system: a potential modulator of endothelial progenitor cells. Hypertens Res 2007; 30: 1017-8.
    • (2007) Hypertens Res , vol.30 , pp. 1017-1018
    • Fukuda, D.1    Sata, M.2
  • 187
    • 15744392514 scopus 로고    scopus 로고
    • Stimulation of endothelial progenitor cells: A new putative therapeutic effect of angiotensin II receptor antagonists
    • Bahlmann FH, de Groot K, Mueller O, Hertel B, Haller H, Fliser D. Stimulation of endothelial progenitor cells: a new putative therapeutic effect of angiotensin II receptor antagonists. Hypertension 2005; 45: 526-9.
    • (2005) Hypertension , vol.45 , pp. 526-529
    • Bahlmann, F.H.1    de Groot, K.2    Mueller, O.3    Hertel, B.4    Haller, H.5    Fliser, D.6
  • 188
    • 3142750485 scopus 로고    scopus 로고
    • Improvement in endothelial progenitor cells from peripheral blood by ramipril therapy in patients with stable coronary artery disease
    • Min TQ, Zhu CJ, Xiang WX, Hui ZJ, Peng SY. Improvement in endothelial progenitor cells from peripheral blood by ramipril therapy in patients with stable coronary artery disease. Cardiovasc Drugs Ther 2004; 18: 203-9.
    • (2004) Cardiovasc Drugs Ther , vol.18 , pp. 203-209
    • Min, T.Q.1    Zhu, C.J.2    Xiang, W.X.3    Hui, Z.J.4    Peng, S.Y.5
  • 189
    • 67349165856 scopus 로고    scopus 로고
    • Molecular genetics of atherosclerosis
    • Roy H, Bhardwaj S, Yla-Herttuala S. Molecular genetics of atherosclerosis. Hum Genet 2009; 125: 467-91.
    • (2009) Hum Genet , vol.125 , pp. 467-491
    • Roy, H.1    Bhardwaj, S.2    Yla-Herttuala, S.3
  • 190
    • 34249015727 scopus 로고    scopus 로고
    • ATP-binding cassette transporter A1 gene I823M polymorphism affects plasma high-density lipoprotein cholesterol level and modifies the effect of low highdensity lipoprotein cholesterol on the risk of coronary artery disease
    • Tsai CT, Hwang JJ, Chiang FT, et al. ATP-binding cassette transporter A1 gene I823M polymorphism affects plasma high-density lipoprotein cholesterol level and modifies the effect of low highdensity lipoprotein cholesterol on the risk of coronary artery disease. Cardiology 2007; 107: 321-8.
    • (2007) Cardiology , vol.107 , pp. 321-328
    • Tsai, C.T.1    Hwang, J.J.2    Chiang, F.T.3
  • 191
    • 0030876982 scopus 로고    scopus 로고
    • Angiotensinogen and angiotensin-I converting enzyme gene polymorphisms and the risk of coronary artery disease in Chinese
    • Ko YL, Ko YS, Wang SM, et al. Angiotensinogen and angiotensin-I converting enzyme gene polymorphisms and the risk of coronary artery disease in Chinese. Hum Genet 1997; 100: 210-4.
    • (1997) Hum Genet , vol.100 , pp. 210-214
    • Ko, Y.L.1    Ko, Y.S.2    Wang, S.M.3
  • 192
    • 0032915912 scopus 로고    scopus 로고
    • Angiotensinogen M235T polymorphism is associated with plasma angiotensinogen and cardiovascular disease
    • Winkelmann BR, Russ AP, Nauck M, et al. Angiotensinogen M235T polymorphism is associated with plasma angiotensinogen and cardiovascular disease. Am Heart J 1999; 137: 698-705.
    • (1999) Am Heart J , vol.137 , pp. 698-705
    • Winkelmann, B.R.1    Russ, A.P.2    Nauck, M.3
  • 193
    • 0033951954 scopus 로고    scopus 로고
    • Genetic polymorphisms and coronary artery disease in the south of France
    • Canavy I, Henry M, Morange PE, et al. Genetic polymorphisms and coronary artery disease in the south of France. Thromb Haemost 2000, 83: 212-6.
    • (2000) Thromb Haemost , vol.83 , pp. 212-216
    • Canavy, I.1    Henry, M.2    Morange, P.E.3
  • 194
    • 0031060669 scopus 로고    scopus 로고
    • Genetic polymorphisms of the renin-angiotensin system and angiographic extent and severity of coronary artery disease: The CORGENE study
    • Jeunemaitre X, Ledru F, Battaglia S, et al. Genetic polymorphisms of the renin-angiotensin system and angiographic extent and severity of coronary artery disease: the CORGENE study. Hum Genet 1997; 99: 66-73.
    • (1997) Hum Genet , vol.99 , pp. 66-73
    • Jeunemaitre, X.1    Ledru, F.2    Battaglia, S.3
  • 195
    • 0034723039 scopus 로고    scopus 로고
    • Genetic polymorphisms in the reninangiotensin system: Relevance for susceptibility to cardiovascular disease
    • Wang JG, Staessen JA. Genetic polymorphisms in the reninangiotensin system: relevance for susceptibility to cardiovascular disease. Eur J Pharmacol 2000; 410: 289-302.
    • (2000) Eur J Pharmacol , vol.410 , pp. 289-302
    • Wang, J.G.1    Staessen, J.A.2
  • 196
    • 0034768684 scopus 로고    scopus 로고
    • Increased risk for ischaemic events is related to combined RAS polymorphism
    • van Geel PP, Pinto YM, Zwinderman AH, et al. Increased risk for ischaemic events is related to combined RAS polymorphism. Heart 2001; 85: 458-62.
    • (2001) Heart , vol.85 , pp. 458-462
    • van Geel, P.P.1    Pinto, Y.M.2    Zwinderman, A.H.3
  • 197
    • 33847367775 scopus 로고    scopus 로고
    • Polymorphisms of the renin-angiotensin system genes predict progression of subclinical coronary atherosclerosis
    • Kretowski A, McFann K, Hokanson JE, et al. Polymorphisms of the renin-angiotensin system genes predict progression of subclinical coronary atherosclerosis. Diabetes 2007; 56: 863-71.
    • (2007) Diabetes , vol.56 , pp. 863-871
    • Kretowski, A.1    McFann, K.2    Hokanson, J.E.3
  • 198
    • 79951673075 scopus 로고    scopus 로고
    • A pharmacogenetic analysis of determinants of hypertension and blood pressure response to angiotensin-converting enzyme inhibitor therapy in patients with vascular disease and healthy individuals
    • Brugts JJ, Isaacs A, de Maat MP, et al. A pharmacogenetic analysis of determinants of hypertension and blood pressure response to angiotensin-converting enzyme inhibitor therapy in patients with vascular disease and healthy individuals. J Hypertens 2011; 29: 509-19.
    • (2011) J Hypertens , vol.29 , pp. 509-519
    • Brugts, J.J.1    Isaacs, A.2    de Maat, M.P.3
  • 199
    • 77953210630 scopus 로고    scopus 로고
    • Renin-angiotensinaldosterone system gene polymorphisms in coronary artery bypass graft surgery patients
    • Ragia G, Nikolaidis E, Tavridou A, et al. Renin-angiotensinaldosterone system gene polymorphisms in coronary artery bypass graft surgery patients. J Renin Angiotensin Aldosterone Syst 2010; 11: 136-45.
    • (2010) J Renin Angiotensin Aldosterone Syst , vol.11 , pp. 136-145
    • Ragia, G.1    Nikolaidis, E.2    Tavridou, A.3
  • 200
    • 60649117132 scopus 로고    scopus 로고
    • Interaction of gender, hypertension, and the angiotensinogen gene haplotypes on the risk of coronary artery disease in a large angiographic cohort
    • Tsai CT, Hwang JJ, Lai LP, Wang YC, Lin JL, Chiang FT. Interaction of gender, hypertension, and the angiotensinogen gene haplotypes on the risk of coronary artery disease in a large angiographic cohort. Atherosclerosis 2009; 203: 249-56.
    • (2009) Atherosclerosis , vol.203 , pp. 249-256
    • Tsai, C.T.1    Hwang, J.J.2    Lai, L.P.3    Wang, Y.C.4    Lin, J.L.5    Chiang, F.T.6
  • 201
    • 70350064389 scopus 로고    scopus 로고
    • Rysz J.Genetic determinants of cardiovascular disease: The renin-angiotensin-aldosterone system, paraoxonases, endothelin-1, nitric oxide synthase and adrenergic receptors
    • Gluba A, Banach M, Mikhailidis DP, Rysz J.Genetic determinants of cardiovascular disease: the renin-angiotensin-aldosterone system, paraoxonases, endothelin-1, nitric oxide synthase and adrenergic receptors. In Vivo 2009; 23: 797-812.
    • (2009) In Vivo , vol.23 , pp. 797-812
    • Gluba, A.1    Banach, M.2    Mikhailidis, D.P.3
  • 202
    • 43449108812 scopus 로고    scopus 로고
    • Economic costs of diabetes in the U.S. In 2007
    • American Diabetes Association
    • American Diabetes Association. Economic costs of diabetes in the U.S. In 2007. Diabetes Care 2008; 31: 596-615.
    • (2008) Diabetes Care , vol.31 , pp. 596-615
  • 203
    • 63149173251 scopus 로고    scopus 로고
    • American Diabetes Association. Standards of medical care in diabetes--2009
    • American Diabetes Association. Standards of medical care in diabetes--2009. Diabetes Care 2009; 32: S13-61.
    • (2009) Diabetes Care , vol.32
  • 204
    • 84857137460 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention, Estimates of diagnosed diabetes now available for all US countries
    • Centers for Disease Control and Prevention. Estimates of diagnosed diabetes now available for all US countries 2008.
    • (2008)
  • 205
    • 18244366915 scopus 로고    scopus 로고
    • The union of vascular and metabolic actions of insulin in sickness and in health
    • Kim JA, Koh KK, Quon MJ. The union of vascular and metabolic actions of insulin in sickness and in health. Arterioscler Thromb Vasc Biol 2005; 25: 889-91.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 889-891
    • Kim, J.A.1    Koh, K.K.2    Quon, M.J.3
  • 206
    • 28244466397 scopus 로고    scopus 로고
    • Inflammatory markers and the metabolic syndrome: Insights from therapeutic interventions
    • Koh KK, Han SH, Quon MJ. Inflammatory markers and the metabolic syndrome: insights from therapeutic interventions. J Am Coll Cardiol 2005; 46: 1978-85.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 1978-1985
    • Koh, K.K.1    Han, S.H.2    Quon, M.J.3
  • 207
    • 19944429129 scopus 로고    scopus 로고
    • Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angiotensin II overexpression
    • Blendea MC, Jacobs D, Stump CS, et al. Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angiotensin II overexpression. Am J Physiol Endocrinol Metab 2005; 288: E353-9.
    • (2005) Am J Physiol Endocrinol Metab , vol.288
    • Blendea, M.C.1    Jacobs, D.2    Stump, C.S.3
  • 208
    • 15944366224 scopus 로고    scopus 로고
    • The renin-angiotensinaldosterone system, glucose metabolism and diabetes
    • Giacchetti G, Sechi LA, Rilli S, Carey RM. The renin-angiotensinaldosterone system, glucose metabolism and diabetes. Trends Endocrinol Metab 2005; 16: 120-6.
    • (2005) Trends Endocrinol Metab , vol.16 , pp. 120-126
    • Giacchetti, G.1    Sechi, L.A.2    Rilli, S.3    Carey, R.M.4
  • 209
    • 13244267189 scopus 로고    scopus 로고
    • Of the renin-angiotensin system and reactive oxygen species Type 2 diabetes and angiotensin II inhibition
    • Leiter LA, Lewanczuk RZ. Of the renin-angiotensin system and reactive oxygen species Type 2 diabetes and angiotensin II inhibition. Am J Hypertens 2005; 18: 121-8.
    • (2005) Am J Hypertens , vol.18 , pp. 121-128
    • Leiter, L.A.1    Lewanczuk, R.Z.2
  • 210
    • 3142781955 scopus 로고    scopus 로고
    • Prevention of type 2 diabetes mellitus through inhibition of the Renin-Angiotensin system
    • Scheen AJ. Prevention of type 2 diabetes mellitus through inhibition of the Renin-Angiotensin system. Drugs 2004; 64: 2537-65.
    • (2004) Drugs , vol.64 , pp. 2537-2565
    • Scheen, A.J.1
  • 211
    • 2342525336 scopus 로고    scopus 로고
    • Angiotensin II type-1 receptor blocker valsartan enhances insulin sensitivity in skeletal muscles of diabetic mice
    • Shiuchi T, Iwai M, Li HS, et al. Angiotensin II type-1 receptor blocker valsartan enhances insulin sensitivity in skeletal muscles of diabetic mice. Hypertension 2004; 43: 1003-10.
    • (2004) Hypertension , vol.43 , pp. 1003-1010
    • Shiuchi, T.1    Iwai, M.2    Li, H.S.3
  • 213
    • 0034095811 scopus 로고    scopus 로고
    • Physiology and pathophysiology of the adipose tissue renin-angiotensin system
    • Engeli S, Negrel R, Sharma AM. Physiology and pathophysiology of the adipose tissue renin-angiotensin system. Hypertension 2000; 35: 1270-7.
    • (2000) Hypertension , vol.35 , pp. 1270-1277
    • Engeli, S.1    Negrel, R.2    Sharma, A.M.3
  • 214
    • 0036266179 scopus 로고    scopus 로고
    • Mature adipocytes inhibit in vitro differentiation of human preadipocytes via angiotensin type 1 receptors
    • Janke J, Engeli S, Gorzelniak K, Luft FC, Sharma AM. Mature adipocytes inhibit in vitro differentiation of human preadipocytes via angiotensin type 1 receptors. Diabetes 2002; 51: 1699-707.
    • (2002) Diabetes , vol.51 , pp. 1699-1707
    • Janke, J.1    Engeli, S.2    Gorzelniak, K.3    Luft, F.C.4    Sharma, A.M.5
  • 215
    • 51849158818 scopus 로고    scopus 로고
    • Renin-angiotensin system blockade and diabetes: Moving the adipose organ from the periphery to the center
    • Lenz O, Fornoni A. Renin-angiotensin system blockade and diabetes: moving the adipose organ from the periphery to the center. Kidney Int 2008; 74: 851-3.
    • (2008) Kidney Int , vol.74 , pp. 851-853
    • Lenz, O.1    Fornoni, A.2
  • 216
    • 0035111403 scopus 로고    scopus 로고
    • Angiotensin II as a trophic factor of white adipose tissue: Stimulation of adipose cell formation
    • Saint-Marc P, Kozak LP, Ailhaud G, Darimont C, Negrel R. Angiotensin II as a trophic factor of white adipose tissue: stimulation of adipose cell formation. Endocrinology 2001; 142: 487-92.
    • (2001) Endocrinology , vol.142 , pp. 487-492
    • Saint-Marc, P.1    Kozak, L.P.2    Ailhaud, G.3    Darimont, C.4    Negrel, R.5
  • 217
    • 0036563232 scopus 로고    scopus 로고
    • Hormonal regulation of the human adipose-tissue renin-angiotensin system: Relationship to obesity and hypertension
    • Gorzelniak K, Engeli S, Janke J, Luft FC, Sharma AM. Hormonal regulation of the human adipose-tissue renin-angiotensin system: relationship to obesity and hypertension. J Hypertens 2002; 20: 965-73.
    • (2002) J Hypertens , vol.20 , pp. 965-973
    • Gorzelniak, K.1    Engeli, S.2    Janke, J.3    Luft, F.C.4    Sharma, A.M.5
  • 218
    • 33947220909 scopus 로고    scopus 로고
    • Effect of antihypertensive agents on plasma adiponectin levels in hypertensive patients with metabolic syndrome
    • Yilmaz MI, Sonmez A, Caglar K, et al. Effect of antihypertensive agents on plasma adiponectin levels in hypertensive patients with metabolic syndrome. Nephrology 2007; 12: 147-53.
    • (2007) Nephrology , vol.12 , pp. 147-153
    • Yilmaz, M.I.1    Sonmez, A.2    Caglar, K.3
  • 219
    • 0027507021 scopus 로고
    • The vasodilator action of insulin. Implications for the insulin hypothesis of hypertension
    • Anderson EA, Mark AL. The vasodilator action of insulin. Implications for the insulin hypothesis of hypertension. Hypertension 1993; 21: 136-41.
    • (1993) Hypertension , vol.21 , pp. 136-141
    • Anderson, E.A.1    Mark, A.L.2
  • 220
    • 34547637839 scopus 로고    scopus 로고
    • NADPH oxidase contributes to vascular inflammation, insulin resistance, and remodeling in the transgenic (mRen2) rat
    • Wei Y, Whaley-Connell AT, Chen K, et al. NADPH oxidase contributes to vascular inflammation, insulin resistance, and remodeling in the transgenic (mRen2) rat. Hypertension 2007; 50: 384-91.
    • (2007) Hypertension , vol.50 , pp. 384-391
    • Wei, Y.1    Whaley-Connell, A.T.2    Chen, K.3
  • 221
    • 38949093861 scopus 로고    scopus 로고
    • Angiotensin II-induced skeletal muscle insulin resistance mediated by NF-kappaB activation via NADPH oxidase
    • Wei Y, Sowers JR, Clark SE, et al. Angiotensin II-induced skeletal muscle insulin resistance mediated by NF-kappaB activation via NADPH oxidase. Am J Physiol Endocrinol Metab 2008; 294: E345-51.
    • (2008) Am J Physiol Endocrinol Metab , vol.294
    • Wei, Y.1    Sowers, J.R.2    Clark, S.E.3
  • 222
    • 34548074442 scopus 로고    scopus 로고
    • Involvement of the pancreatic reninangiotensin system in insulin resistance and the metabolic syndrome
    • Leung PS, de Gasparo M. Involvement of the pancreatic reninangiotensin system in insulin resistance and the metabolic syndrome. J Cardiometab Syndr 2006; 1: 197-203.
    • (2006) J Cardiometab Syndr , vol.1 , pp. 197-203
    • Leung, P.S.1    de Gasparo, M.2
  • 223
    • 33947526470 scopus 로고    scopus 로고
    • The physiology of a local renin-angiotensin system in the pancreas
    • Leung PS. The physiology of a local renin-angiotensin system in the pancreas. J Physiol 2007; 580: 31-7.
    • (2007) J Physiol , vol.580 , pp. 31-37
    • Leung, P.S.1
  • 224
    • 34250311296 scopus 로고    scopus 로고
    • Oxidative stress, glucose metabolism, and the prevention of type 2 diabetes: Pathophysiological insights
    • Shah S, Iqbal M, Karam J, Salifu M, McFarlane SI. Oxidative stress, glucose metabolism, and the prevention of type 2 diabetes: pathophysiological insights. Antioxid Redox Signal 2007; 9: 911-29.
    • (2007) Antioxid Redox Signal , vol.9 , pp. 911-929
    • Shah, S.1    Iqbal, M.2    Karam, J.3    Salifu, M.4    McFarlane, S.I.5
  • 225
    • 33646178955 scopus 로고    scopus 로고
    • Reciprocal relationships between insulin resistance and endothelial dysfunction: Molecular and pathophysiological mechanisms
    • Kim JA, Montagnani M, Koh KK, Quon MJ. Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. Circulation 2006; 113: 1888-904.
    • (2006) Circulation , vol.113 , pp. 1888-1904
    • Kim, J.A.1    Montagnani, M.2    Koh, K.K.3    Quon, M.J.4
  • 226
    • 33846154584 scopus 로고    scopus 로고
    • Reciprocal relationships between abnormal metabolic parameters and endothelial dysfunction
    • Han SH, Quon MJ, Koh KK. Reciprocal relationships between abnormal metabolic parameters and endothelial dysfunction. Curr Opin Lipidol 2007; 18: 58-65.
    • (2007) Curr Opin Lipidol , vol.18 , pp. 58-65
    • Han, S.H.1    Quon, M.J.2    Koh, K.K.3
  • 228
    • 23744511665 scopus 로고    scopus 로고
    • Insulin resistance in spontaneously hypertensive rats is associated with endothelial dysfunction characterized by imbalance between NO and ET-1 production
    • Potenza MA, Marasciulo FL, Chieppa DM, et al. Insulin resistance in spontaneously hypertensive rats is associated with endothelial dysfunction characterized by imbalance between NO and ET-1 production. Am J Physiol Heart Circ Physiol 2005; 289: H813-22.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289
    • Potenza, M.A.1    Marasciulo, F.L.2    Chieppa, D.M.3
  • 229
    • 33845516684 scopus 로고    scopus 로고
    • Treatment of spontaneously hypertensive rats with rosiglitazone and/or enalapril restores balance between vasodilator and vasoconstrictor actions of insulin with simultaneous improvement in hypertension and insulin resistance
    • Potenza MA, Marasciulo FL, Tarquinio M, Quon MJ, Montagnani M. Treatment of spontaneously hypertensive rats with rosiglitazone and/or enalapril restores balance between vasodilator and vasoconstrictor actions of insulin with simultaneous improvement in hypertension and insulin resistance. Diabetes 2006; 55: 3594-603.
    • (2006) Diabetes , vol.55 , pp. 3594-3603
    • Potenza, M.A.1    Marasciulo, F.L.2    Tarquinio, M.3    Quon, M.J.4    Montagnani, M.5
  • 230
    • 34547637839 scopus 로고    scopus 로고
    • NADPH oxidase contributes to vascular inflammation, insulin resistance, and remodeling in the transgenic (mRen2) rat
    • Wei Y, Whaley-Connell AT, Chen K et al. NADPH oxidase contributes to vascular inflammation, insulin resistance, and remodeling in the transgenic (mRen2) rat. Hypertension 2007; 50: 384-91.
    • (2007) Hypertension , vol.50 , pp. 384-391
    • Wei, Y.1    Whaley-Connell, A.T.2    Chen, K.3
  • 232
    • 0025292440 scopus 로고
    • Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man.A novel mechanism for insulin resistance
    • Laakso M, Edelman SV, Brechtel G, Baron AD. Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man.A novel mechanism for insulin resistance. J Clin Invest 1990; 85: 1844-52.
    • (1990) J Clin Invest , vol.85 , pp. 1844-1852
    • Laakso, M.1    Edelman, S.V.2    Brechtel, G.3    Baron, A.D.4
  • 233
    • 57649153175 scopus 로고    scopus 로고
    • Neuroendocrine mechanisms in insulin resistance
    • Sjöstrand M, Eriksson JW. Neuroendocrine mechanisms in insulin resistance. Mol Cell Endocrinol 2009; 297: 104-11.
    • (2009) Mol Cell Endocrinol , vol.297 , pp. 104-111
    • Sjöstrand, M.1    Eriksson, J.W.2
  • 234
    • 0030723979 scopus 로고    scopus 로고
    • Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. A potential role for serine phosphorylation in insulin/ angiotensin II crosstalk
    • Folli F, Kahn CR, Hansen H, Bouchie JL, Feener EP. Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. A potential role for serine phosphorylation in insulin/ angiotensin II crosstalk. J Clin Invest 1997; 100: 2158-69.
    • (1997) J Clin Invest , vol.100 , pp. 2158-2169
    • Folli, F.1    Kahn, C.R.2    Hansen, H.3    Bouchie, J.L.4    Feener, E.P.5
  • 235
    • 0031023734 scopus 로고    scopus 로고
    • Upregulation of vascular angiotensin II receptor gene expression by low-density lipoprotein in vascular smooth muscle cells
    • Nickenig G, Sachinidis A, Michaelsen F, Böhm M, Seewald S, Vetter H. Upregulation of vascular angiotensin II receptor gene expression by low-density lipoprotein in vascular smooth muscle cells. Circulation 1997; 95: 473-8.
    • (1997) Circulation , vol.95 , pp. 473-478
    • Nickenig, G.1    Sachinidis, A.2    Michaelsen, F.3    Böhm, M.4    Seewald, S.5    Vetter, H.6
  • 236
    • 0037009883 scopus 로고    scopus 로고
    • Angiotensin II is associated with activation of NF-kappaB-mediated genes and downregulation of PPARs
    • Tham DM, Martin-McNulty B, Wang YX, et al. Angiotensin II is associated with activation of NF-kappaB-mediated genes and downregulation of PPARs. Physiol Genomics 2002; 11: 21-30.
    • (2002) Physiol Genomics , vol.11 , pp. 21-30
    • Tham, D.M.1    Martin-McNulty, B.2    Wang, Y.X.3
  • 237
    • 0036882119 scopus 로고    scopus 로고
    • PPARalpha activator effects on Ang II-induced vascular oxidative stress and inflammation
    • Diep QN, Amiri F, Touyz RM, et al. PPARalpha activator effects on Ang II-induced vascular oxidative stress and inflammation. Hypertension 2002; 40: 866-71.
    • (2002) Hypertension , vol.40 , pp. 866-871
    • Diep, Q.N.1    Amiri, F.2    Touyz, R.M.3
  • 238
    • 0034989969 scopus 로고    scopus 로고
    • Transcriptional suppression of type 1 angiotensin II receptor gene expression by peroxisome proliferator-activated receptor-gamma in vascular smooth muscle cells
    • Sugawara A, Takeuchi K, Uruno A, et al. Transcriptional suppression of type 1 angiotensin II receptor gene expression by peroxisome proliferator-activated receptor-gamma in vascular smooth muscle cells. Endocrinology 2001; 142: 3125-34.
    • (2001) Endocrinology , vol.142 , pp. 3125-3134
    • Sugawara, A.1    Takeuchi, K.2    Uruno, A.3
  • 239
    • 64849104331 scopus 로고    scopus 로고
    • Vascular-protective effects of high-density lipoprotein include the downregulation of the angiotensin II type 1 receptor
    • Van Linthout S, Spillmann F, Lorenz M, et al. Vascular-protective effects of high-density lipoprotein include the downregulation of the angiotensin II type 1 receptor. Hypertension 2009; 53: 682-7.
    • (2009) Hypertension , vol.53 , pp. 682-687
    • van Linthout, S.1    Spillmann, F.2    Lorenz, M.3
  • 240
    • 0027522750 scopus 로고
    • Antihypertensive drug therapy and the initiation of treatment for diabetes mellitus
    • Gurwitz JH, Bohn RL, Glynn RJ, Monane M, Mogun H, Avorn J. Antihypertensive drug therapy and the initiation of treatment for diabetes mellitus. Ann Intern Med 1993; 118: 273-8.
    • (1993) Ann Intern Med , vol.118 , pp. 273-278
    • Gurwitz, J.H.1    Bohn, R.L.2    Glynn, R.J.3    Monane, M.4    Mogun, H.5    Avorn, J.6
  • 241
    • 0034688194 scopus 로고    scopus 로고
    • Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients.The Heart Outcomes Prevention Evaluation Study Investigators
    • Yusuf S, Sleight P, Pogue J, Bosch J, Davies R, Dagenais G. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients.The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000; 342: 145-53.
    • (2000) N Engl J Med , vol.342 , pp. 145-153
    • Yusuf, S.1    Sleight, P.2    Pogue, J.3    Bosch, J.4    Davies, R.5    Dagenais, G.6
  • 242
    • 0037160968 scopus 로고    scopus 로고
    • Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): A randomised trial against atenolol
    • Dahlöf B, Devereux RB, Kjeldsen SE, et al. Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. Lancet 2002; 359: 995-1003.
    • (2002) Lancet , vol.359 , pp. 995-1003
    • Dahlöf, B.1    Devereux, R.B.2    Kjeldsen, S.E.3
  • 243
    • 21844434198 scopus 로고    scopus 로고
    • Effects of candesartan on the development of a new diagnosis of diabetes mellitus in patients with heart failure
    • Yusuf S, Ostergren JB, Gerstein HC, et al. Effects of candesartan on the development of a new diagnosis of diabetes mellitus in patients with heart failure. Circulation 2005; 112: 48-53.
    • (2005) Circulation , vol.112 , pp. 48-53
    • Yusuf, S.1    Ostergren, J.B.2    Gerstein, H.C.3
  • 244
    • 2942635317 scopus 로고    scopus 로고
    • Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: The VALUE randomised trial
    • Julius S, Kjeldsen SE, Weber M, et al. Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial. Lancet 2004; 363: 2022-31.
    • (2004) Lancet , vol.363 , pp. 2022-2031
    • Julius, S.1    Kjeldsen, S.E.2    Weber, M.3
  • 245
    • 0042878465 scopus 로고    scopus 로고
    • Pleiotropic effects of angiotensin II receptor blocker in hypertensive patients
    • Koh KK, Ahn JY, Han SH, et al. Pleiotropic effects of angiotensin II receptor blocker in hypertensive patients. J Am Coll Cardiol 2003; 42: 905-10.
    • (2003) J Am Coll Cardiol , vol.42 , pp. 905-910
    • Koh, K.K.1    Ahn, J.Y.2    Han, S.H.3
  • 246
    • 33644653151 scopus 로고    scopus 로고
    • Antiinflammatory and metabolic effects of candesartan in hypertensive patients
    • Koh KK, Quon MJ, Han SH, Chung WJ, Lee Y, Shin EK. Antiinflammatory and metabolic effects of candesartan in hypertensive patients. Int J Cardiol 2006; 108: 96-100.
    • (2006) Int J Cardiol , vol.108 , pp. 96-100
    • Koh, K.K.1    Quon, M.J.2    Han, S.H.3    Chung, W.J.4    Lee, Y.5    Shin, E.K.6
  • 247
    • 0344541709 scopus 로고    scopus 로고
    • Statin-sensitive dysregulated AT1 receptor function and density in hypercholesterolemic men
    • Nickenig G, Bäumer AT, Temur Y, Kebben D, Jockenhövel F, Böhm M. Statin-sensitive dysregulated AT1 receptor function and density in hypercholesterolemic men. Circulation 1999; 100: 2131-4.
    • (1999) Circulation , vol.100 , pp. 2131-2134
    • Nickenig, G.1    Bäumer, A.T.2    Temur, Y.3    Kebben, D.4    Jockenhövel, F.5    Böhm, M.6
  • 248
    • 0026520888 scopus 로고
    • Isoprenoid metabolism is required for stimulation of the respiratory burst oxidase of HL-60 cells
    • Bokoch GM, Prossnitz V. Isoprenoid metabolism is required for stimulation of the respiratory burst oxidase of HL-60 cells. J Clin Invest 1992; 89: 402-8.
    • (1992) J Clin Invest , vol.89 , pp. 402-408
    • Bokoch, G.M.1    Prossnitz, V.2
  • 249
    • 0141924553 scopus 로고    scopus 로고
    • A novel pleiotropic effect of statins: Prevention of cardiac hypertrophy by cholesterolindependent mechanisms
    • Nakagami H, Jensen KS, Liao JK. A novel pleiotropic effect of statins: prevention of cardiac hypertrophy by cholesterolindependent mechanisms. Ann Med 2003; 35: 398-403.
    • (2003) Ann Med , vol.35 , pp. 398-403
    • Nakagami, H.1    Jensen, K.S.2    Liao, J.K.3
  • 250
    • 27444437661 scopus 로고    scopus 로고
    • Beneficial vascular and metabolic effects of peroxisome proliferator-activated receptor-alpha activators
    • Nov
    • Han SH, Quon MJ, Koh KK. Beneficial vascular and metabolic effects of peroxisome proliferator-activated receptor-alpha activators. Hypertension 2005 Nov; 46: 1086-92.
    • (2005) Hypertension , vol.46 , pp. 1086-1092
    • Han, S.H.1    Quon, M.J.2    Koh, K.K.3
  • 251
    • 38649136909 scopus 로고    scopus 로고
    • Vascular and metabolic effects of treatment of combined hyperlipidemia: Focus on statins and fibrates
    • Koh KK, Quon MJ, Rosenson RS, Chung WJ, Han SH. Vascular and metabolic effects of treatment of combined hyperlipidemia: focus on statins and fibrates. Int J Cardiol 2008; 124: 149-59.
    • (2008) Int J Cardiol , vol.124 , pp. 149-159
    • Koh, K.K.1    Quon, M.J.2    Rosenson, R.S.3    Chung, W.J.4    Han, S.H.5
  • 252
    • 0036842574 scopus 로고    scopus 로고
    • Antiinflammatory and antiarteriosclerotic effects of pioglitazone
    • Ishibashi M, Egashira K, Hiasa K, et al. Antiinflammatory and antiarteriosclerotic effects of pioglitazone. Hypertension 2002; 40: 687-93.
    • (2002) Hypertension , vol.40 , pp. 687-693
    • Ishibashi, M.1    Egashira, K.2    Hiasa, K.3
  • 253
    • 0842311509 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma: Implications for cardiovascular disease
    • Hsueh WA, Bruemmer D. Peroxisome proliferator-activated receptor gamma: implications for cardiovascular disease. Hypertension 2004; 43: 297-305.
    • (2004) Hypertension , vol.43 , pp. 297-305
    • Hsueh, W.A.1    Bruemmer, D.2
  • 254
    • 0037231474 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands increase release of nitric oxide from endothelial cells
    • Calnek DS, Mazzella L, Roser S, Roman J, Hart CM. Peroxisome proliferator-activated receptor gamma ligands increase release of nitric oxide from endothelial cells. Arterioscler Thromb Vasc Biol 2003; 23: 52-7.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 52-57
    • Calnek, D.S.1    Mazzella, L.2    Roser, S.3    Roman, J.4    Hart, C.M.5
  • 255
    • 78650919357 scopus 로고    scopus 로고
    • Role of adipose tissue renin-angiotensin system in metabolic and inflammatory diseases associated with obesity
    • Yvan-Charvet L, Quignard-Boulangé A. Role of adipose tissue renin-angiotensin system in metabolic and inflammatory diseases associated with obesity. Kidney Int 2011; 79: 162-8.
    • (2011) Kidney Int , vol.79 , pp. 162-168
    • Yvan-Charvet, L.1    Quignard-Boulangé, A.2
  • 257
    • 79957673691 scopus 로고    scopus 로고
    • The influence of body mass index and renin-angiotensin-aldosterone system activity on the relationship between 25-hydroxyvitamin D and adiponectin in Caucasian men
    • Vaidya A, Forman JP, Underwood PC, et al. The influence of body mass index and renin-angiotensin-aldosterone system activity on the relationship between 25-hydroxyvitamin D and adiponectin in Caucasian men. Eur J Endocrinol 2011; 164: 995-1002.
    • (2011) Eur J Endocrinol , vol.164 , pp. 995-1002
    • Vaidya, A.1    Forman, J.P.2    Underwood, P.C.3
  • 259
    • 77956300089 scopus 로고    scopus 로고
    • Renin-angiotensinaldosterone system in patients with sleep apnoea: Prevalence of primary aldosteronism
    • Di Murro A, Petramala L, Cotesta D, et al. Renin-angiotensinaldosterone system in patients with sleep apnoea: prevalence of primary aldosteronism. J Renin Angiotensin Aldosterone Syst 2010; 11: 165-72.
    • (2010) J Renin Angiotensin Aldosterone Syst , vol.11 , pp. 165-172
    • Di Murro, A.1    Petramala, L.2    Cotesta, D.3
  • 260
    • 72749083202 scopus 로고    scopus 로고
    • The antiproteinuric effect of the blockade of the reninangiotensin-aldosterone system (RAAS) in obese patients. Which treatment option is the most effective?
    • Morales E, Huerta A, Gutiérrez E, Gutiérrez Solís E, Segura J, Praga M. The antiproteinuric effect of the blockade of the reninangiotensin-aldosterone system (RAAS) in obese patients. Which treatment option is the most effective? Nefrologia 2009; 29: 421-9.
    • (2009) Nefrologia , vol.29 , pp. 421-429
    • Morales, E.1    Huerta, A.2    Gutiérrez, E.3    Gutiérrez, S.E.4    Segura, J.5    Praga, M.6
  • 262
    • 0346059332 scopus 로고    scopus 로고
    • Angiotensinogen gene polymorphisms: Relationship to blood pressure response to antihypertensive treatment. Results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs Atenolol (SILVHIA) trial
    • Kurland L, Liljedahl U, Karlsson J, et al. Angiotensinogen gene polymorphisms: relationship to blood pressure response to antihypertensive treatment. Results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs Atenolol (SILVHIA) trial. Am J Hypertens 2004; 17: 8-13.
    • (2004) Am J Hypertens , vol.17 , pp. 8-13
    • Kurland, L.1    Liljedahl, U.2    Karlsson, J.3
  • 263
    • 0036246434 scopus 로고    scopus 로고
    • Aldosterone synthase (CYP11B2)-344 C/T polymorphism is related to antihypertensive response: Result from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) trial
    • Kurland L, Melhus H, Karlsson J, et al. Aldosterone synthase (CYP11B2)-344 C/T polymorphism is related to antihypertensive response: result from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) trial. Am J Hypertens; 15: 389-93.
    • Am J Hypertens , vol.15 , pp. 389-393
    • Kurland, L.1    Melhus, H.2    Karlsson, J.3
  • 264
    • 33646838795 scopus 로고    scopus 로고
    • Functional variants of the angiotensinogen gene determine antihypertensive responses to angiotensin-converting enzyme inhibitors in subjects of African origin
    • Woodiwiss AJ, Nkeh B, Samani NJ, et al. Functional variants of the angiotensinogen gene determine antihypertensive responses to angiotensin-converting enzyme inhibitors in subjects of African origin. J Hypertens 2006; 24: 1057-64.
    • (2006) J Hypertens , vol.24 , pp. 1057-1064
    • Woodiwiss, A.J.1    Nkeh, B.2    Samani, N.J.3
  • 265
    • 0026669336 scopus 로고
    • Molecular basis of human hypertension: Role of angiotensinogen
    • Jeunemaitre X, Soubrier F, Kotelevtsev YV, et al. Molecular basis of human hypertension: role of angiotensinogen. Cell 1992; 72: 169-80.
    • (1992) Cell , vol.72 , pp. 169-180
    • Jeunemaitre, X.1    Soubrier, F.2    Kotelevtsev, Y.V.3
  • 266
    • 0347320660 scopus 로고    scopus 로고
    • Identification of angiotensin I in several vertebrate species: Its structural and functional evolution
    • Takei Y, Joss JM, Kloas W, Rankin JC. Identification of angiotensin I in several vertebrate species: its structural and functional evolution. Gen Comp Endocrinol 2004; 135: 286-92.
    • (2004) Gen Comp Endocrinol , vol.135 , pp. 286-292
    • Takei, Y.1    Joss, J.M.2    Kloas, W.3    Rankin, J.C.4
  • 267
    • 0027942731 scopus 로고
    • Identification of cell type-dependent enhancer core element located in the 3'-downstream region of the human angiotensinogen gene
    • Nibu Y, Takahashi S, Tanimoto K, Murakami K, Fukamizu A. Identification of cell type-dependent enhancer core element located in the 3'-downstream region of the human angiotensinogen gene. J Biol Chem 1994; 269: 28598-605.
    • (1994) J Biol Chem , vol.269 , pp. 28598-28605
    • Nibu, Y.1    Takahashi, S.2    Tanimoto, K.3    Murakami, K.4    Fukamizu, A.5
  • 268
    • 0030049446 scopus 로고    scopus 로고
    • Chronic hypertension and altered baroreflex responses in transgenic mice containing the human renin and human angiotensinogen genes
    • Merrill DC, Thompson MW, Carney CL, et al. Chronic hypertension and altered baroreflex responses in transgenic mice containing the human renin and human angiotensinogen genes. J Clin Invest 1996; 97: 1047-55.
    • (1996) J Clin Invest , vol.97 , pp. 1047-1055
    • Merrill, D.C.1    Thompson, M.W.2    Carney, C.L.3
  • 269
    • 0026753520 scopus 로고
    • Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes
    • Ganten D, Wagner J, Zeh K, et al. Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes. Proc Natl Acad Sci USA 1992; 89: 7806-10.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7806-7810
    • Ganten, D.1    Wagner, J.2    Zeh, K.3
  • 270
    • 0018465575 scopus 로고
    • Relation between blood pressure and renin, renin substrate, angiotensin II, aldosterone and urinary sodium and potassium in 574 ambulatory subjects
    • Walker WG, Whelton PK, Saito H, Russell RP, Hermann J. Relation between blood pressure and renin, renin substrate, angiotensin II, aldosterone and urinary sodium and potassium in 574 ambulatory subjects. Hypertension 1979; 1: 287-91.
    • (1979) Hypertension , vol.1 , pp. 287-291
    • Walker, W.G.1    Whelton, P.K.2    Saito, H.3    Russell, R.P.4    Hermann, J.5
  • 272
    • 0026056549 scopus 로고
    • Angiotensinogen: An attractive and underrated participant in hypertension and inflammation
    • Ménard J, el Amrani AI, Savoie F, Bouhnik J. Angiotensinogen: an attractive and underrated participant in hypertension and inflammation. Hypertension 1991; 18: 705-7.
    • (1991) Hypertension , vol.18 , pp. 705-707
    • Ménard, J.1    el Amrani, A.I.2    Savoie, F.3    Bouhnik, J.4
  • 273
    • 0025322560 scopus 로고
    • Generation of transgenic mice with elevated blood pressure by introduction of the rat renin and angiotensinogen genes
    • Ohkubo H, Kawakami H, Kakehi Y, et al. Generation of transgenic mice with elevated blood pressure by introduction of the rat renin and angiotensinogen genes. Proc Natl Acad Sci USA 1990; 87: 5153-7.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 5153-5157
    • Ohkubo, H.1    Kawakami, H.2    Kakehi, Y.3
  • 274
    • 0027205144 scopus 로고
    • A molecular variant of angiotensinogen associated with preeclampsia
    • Ward K, Hata A, Jeunemaitre X, et al. A molecular variant of angiotensinogen associated with preeclampsia. Nat Genet 1993; 4: 59-61.
    • (1993) Nat Genet , vol.4 , pp. 59-61
    • Ward, K.1    Hata, A.2    Jeunemaitre, X.3
  • 275
    • 0030893575 scopus 로고    scopus 로고
    • A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro
    • Inoue I, Nakajima T, Williams CS, et al. A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro. J Clin Invest 1997; 99: 1786-97.
    • (1997) J Clin Invest , vol.99 , pp. 1786-1797
    • Inoue, I.1    Nakajima, T.2    Williams, C.S.3
  • 276
    • 0029019491 scopus 로고
    • A mutation of angiotensinogen in a patient with preeclampsia leads to altered kinetics of the renin-angiotensin system
    • Inoue I, Rohrwasser A, Helin C, et al. A mutation of angiotensinogen in a patient with preeclampsia leads to altered kinetics of the renin-angiotensin system. J Biol Chem 1995; 270: 11430-6.
    • (1995) J Biol Chem , vol.270 , pp. 11430-11436
    • Inoue, I.1    Rohrwasser, A.2    Helin, C.3
  • 277
    • 0030867545 scopus 로고    scopus 로고
    • Angiotensinogen T235 expression is elevated in decidual spiral arteries
    • Morgan T, Craven C, Nelson L, Lalouel JM, Ward K. Angiotensinogen T235 expression is elevated in decidual spiral arteries. J Clin Invest 1997; 100: 1406-15.
    • (1997) J Clin Invest , vol.100 , pp. 1406-1415
    • Morgan, T.1    Craven, C.2    Nelson, L.3    Lalouel, J.M.4    Ward, K.5
  • 278
    • 0037771145 scopus 로고    scopus 로고
    • Angiotensinogen gene polymorphism, plasma angiotensinogen, and risk of hypertension and ischemic heart disease: A meta-analysis
    • Sethi AA, Nordestgaard BG, Tybjaerg-Hansen A. Angiotensinogen gene polymorphism, plasma angiotensinogen, and risk of hypertension and ischemic heart disease: a meta-analysis. Arterioscler Thromb Vasc Biol 2003, 23: 1269-75.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1269-1275
    • Sethi, A.A.1    Nordestgaard, B.G.2    Tybjaerg-Hansen, A.3
  • 279
    • 0010610371 scopus 로고    scopus 로고
    • Role of C/A polymorphism at-20 on the expression of human angiotensinogen gene
    • Zhao YY, Zhou J, Narayanan CS, Cui Y, Kumar A. Role of C/A polymorphism at-20 on the expression of human angiotensinogen gene. Hypertension 1999; 33: 108-15.
    • (1999) Hypertension , vol.33 , pp. 108-115
    • Zhao, Y.Y.1    Zhou, J.2    Narayanan, C.S.3    Cui, Y.4    Kumar, A.5
  • 280
    • 0033602180 scopus 로고    scopus 로고
    • Orphan receptor Arp-1 binds to the nucleotide sequence located between TATA box and transcriptional initiation site of the human angiotensinogen gene and reduces estrogen induced promoter activity
    • Narayanan CS, Cui Y, Zhao YY, Zhou J, Kumar A. Orphan receptor Arp-1 binds to the nucleotide sequence located between TATA box and transcriptional initiation site of the human angiotensinogen gene and reduces estrogen induced promoter activity. Mol Cell Endocrinol 1999; 148: 79-86.
    • (1999) Mol Cell Endocrinol , vol.148 , pp. 79-86
    • Narayanan, C.S.1    Cui, Y.2    Zhao, Y.Y.3    Zhou, J.4    Kumar, A.5
  • 281
    • 0034073616 scopus 로고    scopus 로고
    • Polymorphism in oestrogen response element associated with variation in plasma angiotensinogen concentrations in healthy pregnant women
    • Morgan L, Crawshaw S, Baker PN, Broughton Pipkin F, Kalsheker N. Polymorphism in oestrogen response element associated with variation in plasma angiotensinogen concentrations in healthy pregnant women. J Hypertens 2000; 18: 553-7.
    • (2000) J Hypertens , vol.18 , pp. 553-557
    • Morgan, L.1    Crawshaw, S.2    Baker, P.N.3    Broughton, P.F.4    Kalsheker, N.5
  • 282
    • 0035679807 scopus 로고    scopus 로고
    • Angiotensinogen gene core promoter variants and non-modulating hypertension
    • Hilgers KF, Delles C, Veelken R, Schmieder RE. Angiotensinogen gene core promoter variants and non-modulating hypertension. Hypertension 2001; 38: 1250-4.
    • (2001) Hypertension , vol.38 , pp. 1250-1254
    • Hilgers, K.F.1    Delles, C.2    Veelken, R.3    Schmieder, R.E.4
  • 283
    • 0037126078 scopus 로고    scopus 로고
    • Angiotensinogen gene promoter region variant modifies body size-ambulatory blood pressure relations in hypertension
    • Tiago AD, Samani NJ, Candy GP, et al. Angiotensinogen gene promoter region variant modifies body size-ambulatory blood pressure relations in hypertension. Circulation 2002; 106: 1483-7.
    • (2002) Circulation , vol.106 , pp. 1483-1487
    • Tiago, A.D.1    Samani, N.J.2    Candy, G.P.3
  • 284
    • 0037184109 scopus 로고    scopus 로고
    • Angiotensinogen gene polymorphism at-217 affects basal promoter activity and is associated with hypertension in African-Americans
    • Jain S, Tang X, Narayanan CS, et al. Angiotensinogen gene polymorphism at-217 affects basal promoter activity and is associated with hypertension in African-Americans. J Biol Chem 2002; 277: 36889-96.
    • (2002) J Biol Chem , vol.277 , pp. 36889-36896
    • Jain, S.1    Tang, X.2    Narayanan, C.S.3
  • 285
    • 15044365863 scopus 로고    scopus 로고
    • A single-nucleotide polymorphism in human angiotensinogen gene is associated with essential hypertension and affects glucocorticoid induced promoter activity
    • Jain S, Li Y, Patil S, Kumar A. A single-nucleotide polymorphism in human angiotensinogen gene is associated with essential hypertension and affects glucocorticoid induced promoter activity. J Mol Med 2005; 83: 121-31.
    • (2005) J Mol Med , vol.83 , pp. 121-131
    • Jain, S.1    Li, Y.2    Patil, S.3    Kumar, A.4
  • 286
    • 0036862309 scopus 로고    scopus 로고
    • Detection of putative functional angiotensinogen (AGT) gene variants controlling plasma AGT levels by combined segregation-linkage analysis
    • Brand E, Chatelain N, Paillard F, et al. Detection of putative functional angiotensinogen (AGT) gene variants controlling plasma AGT levels by combined segregation-linkage analysis. Eur J Hum Genet 2002; 10: 715-23.
    • (2002) Eur J Hum Genet , vol.10 , pp. 715-723
    • Brand, E.1    Chatelain, N.2    Paillard, F.3
  • 287
    • 0036137018 scopus 로고    scopus 로고
    • Nucleotide diversity and haplotype structure of the human angiotensinogen gene in two populations
    • Nakajima T, Jorde LB, Ishigami T, et al. Nucleotide diversity and haplotype structure of the human angiotensinogen gene in two populations. Am J Hum Genet 2002; 70: 108-23.
    • (2002) Am J Hum Genet , vol.70 , pp. 108-123
    • Nakajima, T.1    Jorde, L.B.2    Ishigami, T.3
  • 288
    • 0037996763 scopus 로고    scopus 로고
    • Associations between hypertension and genes in the renin-angiotensin system
    • Zhu X, Chang YP, Yan D, et al. Associations between hypertension and genes in the renin-angiotensin system. Hypertension 2003; 41: 1027-34.
    • (2003) Hypertension , vol.41 , pp. 1027-1034
    • Zhu, X.1    Chang, Y.P.2    Yan, D.3
  • 289
    • 0037313361 scopus 로고    scopus 로고
    • Linkage disequilibrium and haplotype diversity in the genes of the renin-angiotensin system: Findings from the family blood pressure program
    • Zhu X, Yan D, Cooper RS, et al. Linkage disequilibrium and haplotype diversity in the genes of the renin-angiotensin system: findings from the family blood pressure program. Genome Res 2003; 13: 173-81.
    • (2003) Genome Res , vol.13 , pp. 173-181
    • Zhu, X.1    Yan, D.2    Cooper, R.S.3
  • 290
    • 0037217399 scopus 로고    scopus 로고
    • Angiotensinogen gene haplotype and hypertension: Interaction with ACE gene I allele
    • Tsai CT, Fallin D, Chiang FT, et al. Angiotensinogen gene haplotype and hypertension: interaction with ACE gene I allele. Hypertension 2003; 41: 9-15.
    • (2003) Hypertension , vol.41 , pp. 9-15
    • Tsai, C.T.1    Fallin, D.2    Chiang, F.T.3
  • 291
    • 31144441123 scopus 로고    scopus 로고
    • Haplotype association analysis of AGT variants with hypertension-related traits: The HyperGEN study
    • Gu CC, Chang YP, Hunt SC, et al. Haplotype association analysis of AGT variants with hypertension-related traits: the HyperGEN study. Hum Hered 2005; 60: 164-76.
    • (2005) Hum Hered , vol.60 , pp. 164-176
    • Gu, C.C.1    Chang, Y.P.2    Hunt, S.C.3
  • 292
    • 7644223103 scopus 로고    scopus 로고
    • Angiotensinogen promoter B-haplotype associated with cerebral small vessel disease enhances basal transcriptional activity
    • Schmidt H, Aulchenko YS, Schweighofer N, et al. Angiotensinogen promoter B-haplotype associated with cerebral small vessel disease enhances basal transcriptional activity. Stroke 2004; 35: 2592-7.
    • (2004) Stroke , vol.35 , pp. 2592-2597
    • Schmidt, H.1    Aulchenko, Y.S.2    Schweighofer, N.3
  • 293
    • 0036267743 scopus 로고    scopus 로고
    • Contribution of Sp1 to initiation of transcription of angiotensinogen
    • Rohrwasser A, Zhang S, Dillon HF, et al. Contribution of Sp1 to initiation of transcription of angiotensinogen. J Hum Genet 2002; 47: 249-56.
    • (2002) J Hum Genet , vol.47 , pp. 249-256
    • Rohrwasser, A.1    Zhang, S.2    Dillon, H.F.3
  • 294
    • 79957832677 scopus 로고    scopus 로고
    • Plasma renin activity predicts cardiovascular mortality in the Heart Outcomes Prevention Evaluation (HOPE) study
    • Verma S, Gupta M, Holmes DT, et al. Plasma renin activity predicts cardiovascular mortality in the Heart Outcomes Prevention Evaluation (HOPE) study. Eur Heart J 2011; 32: 2135-42.
    • (2011) Eur Heart J , vol.32 , pp. 2135-2142
    • Verma, S.1    Gupta, M.2    Holmes, D.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.