A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro

Journal of Clinical Investigation

Volumn 99, Issue 7, 1997, Pages 1786-1797

  Inoue, Ituro ^a   Nakajima, Toshiaki ^a   Williams, Christopher S ^a   Quackenbush, John ^a   Puryear, Robert ^a   Powers, Michael ^a   Cheng, Tong ^a   Ludwig, Erwin H ^a   Sharma, Arya M ^b   Hata, Akira ^c   Jeunemaitre, Xavier ^d   Lalouel, Jean Marc ^a,e  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c HOKKAIDO UNIVERSITY   (Japan)

^d HÔPITAL BROUSSAIS   (France)

^e UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

angiotensinogen; essential hypertension; molecular variant; promoter; transcription

Indexed keywords

ANGIOTENSIN; ANGIOTENSINOGEN;

AMINO ACID SUBSTITUTION; ARTICLE; DNA BINDING; ENZYME DEFICIENCY; ESSENTIAL HYPERTENSION; GENETIC LINKAGE; GENETIC PREDISPOSITION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION REGULATION;

EID: 0030893575     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119343     Document Type: Article

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