High-affinity prorenin binding to cardiac man-6-P/IGF-II receptors precedes proteolytic activation to renin

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 280, Issue 4 49-4, 2001, Pages

  Saris, Jasper J ^a   Derkx, Frans H M ^a   De Bruin, René J A ^a   Dekkers, Dick H W ^a   Lamers, Jos M J ^a   Saxena, Pramod R ^a   Schalekamp, Maarten A D H ^a   Danser, A H Jan ^a,b  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

Cardiomyocytes; Fibroblasts; Heart; Kidney; Local renin angiotensin system

Indexed keywords

ANGIOTENSIN; PRORENIN; RENIN; SOMATOMEDIN B RECEPTOR;

AMNION FLUID; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING KINETICS; BINDING SITE; CELL LYSATE; CONTROLLED STUDY; DISSOCIATION CONSTANT; FIBROBLAST; HALF LIFE TIME; HEART MUSCLE CELL; INTERNALIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; RECEPTOR BINDING; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

EID: 0035005608     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2001.280.4.h1706     Document Type: Article

References (60)

1. Admiraal PJJ, van Kesteren CAM, Danser AHJ, Derkx FHM, Sluiter W, and Schalekamp MADH. Uptake and proteolytic activation of prorenin by cultured human endothelial cells. J Hypertens 17: 621-629, 1999.
2. Aeed PA, Guido DM, Mathews WR, and Elhammer AP. Characterization of the oligosaccharide structures on recombinant human prorenin expressed in Chinese hamster ovary cells. Biochemistry 31: 6951-6961, 1992.
3. Baba K, Doi Y, Yamaguchi T, Yano K, and Hashiba K. Production of active and inactive renin by adrenal expiant cultures and the existence of a prorenin activating enzyme in the adrenal gland. Jpn Heart J 33: 465-476, 1992.
4. Ballesteros M, Scott CD, and Baxter RC. Developmental regulation of insulin-like growth factor-II/mannose 6-phosphate receptor mRNA in the rat. Biochem Biophys Res Commun 172: 775-779, 1990.
5. Barrett JD, Eggena P, and Sambhi MP. Activation of rat plasma renin. Endocrinology 108: 778-785, 1981.
6. Beaubien G, Schafer MK, Weihe E, Dong W, Chretien M, Seidah NG, and Day R. The distinct gene expression of the pro-hormone convertases in the rat heart suggests potential substrates. Cell Tissue Res 279: 539-549, 1995.
7. Beynon RJ and Bond JS. Proteolytic enzymes: a practical approach. In: The Practical Approach Series (1st ed.), edited by Rickwood D and Hames BD. Oxford: IRL, 1989, p. 259.
8. Campbell DJ and Valentijn AJ. Identification of vascular renin-binding proteins by chemical cross-linking: inhibition of binding of renin by renin inhibitors. J Hypertens 12: 879-890, 1994.
9. Costello M, Baxter RC, and Scott CD. Regulation of soluble insulin-like growth factor II/mannose 6-phosphate receptor in human serum: measurement by enzyme-linked immunosorbent assay. J Clin Endocrinol Metab 84: 611-617, 1999.
10. Dahms NM, Lobel P, and Kornfeld S. Mannose 6-phosphate receptors and lysosomal enzyme targeting. J Biol Chem 264: 12115-12118, 1989.
11. Danser AHJ, Derkx FHM, Schalekamp MADH, Hense HW, Riegger GAJ, and Schunkert H. Determinants of interindividual variation of renin and prorenin concentrations: evidence for a sexual dimorphism of (pro)renin levels in humans. J Hypertens 16: 853-862, 1998.
12. Danser AHJ, van den Dorpel MA, Deinum J, Derkx FHM, Franken AAM, Peperkamp E, de Jong PTVM, and Schalekamp MADH. Renin, prorenin, and immunoreactive renin in vitreous fluid from eyes with and without diabetic retinopathy. J Clin Endocrinol Metab 68: 160-167, 1989.
13. Danser AHJ, van Kats JP, Admiraal PJJ, Derkx FHM, Lamers JMJ, Verdouw PD, Saxena PR, and Schalekamp MADH. Cardiac renin and angiotensins. Uptake from plasma versus in situ synthesis. Hypertension 24: 37-48, 1994.
14. Danser AHJ, van Kesteren CAM, Bax WA, Tavenier M, Derkx FHM, Saxena PR, and Schalekamp MADH. Prorenin, renin, angiotensinogen, and angiotensin-converting enzyme in normal and failing human hearts: evidence for renin binding. Circulation 96: 220-226, 1997.
15. Deinum J, Derkx FHM, and Schalekamp MADH. Improved immunoradiometric assay for plasma renin. Clin Chem 45: 847-854, 1999.
16. Deinum J, Derkx FHM, and Schalekamp MADH. Probing epitopes on human prorenin during its proteolytic and nonproteolytic activation. Biochim Biophys Acta 1388: 386-396, 1998.
17. De Lannoy LM, Danser AHJ, Bouhuizen AMB, Saxena PR, and Schalekamp MADH. Localization and production of angiotensin II in the isolated perfused rat heart. Hypertension 31: 1111-1117, 1998.
18. De Lannoy LM, Danser AHJ, van Kats JP, Schoemaker RG, Saxena PR, and Schalekamp MADH. Renin-angiotensin system components in the interstitial fluid of the isolated perfused rat heart: local production of angiotensin I. Hypertension 29: 1240-1251, 1997.
19. Dennis PA and Rifkin DB. Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor. Proc Natl Acad Sci USA 88: 580-584, 1991.
20. Derkx FHM, Alberda AT, Zeilmaker GH, and Schalekamp MADH. High concentrations of immunoreactive renin, prorenin and enzymatically active renin in human ovarian follicular fluid. Br J Obstet Gynaecol 94: 4-9, 1987.
21. Derkx FHM, Schalekamp MP, and Schalekamp MADH. Two-step prorenin-renin conversion isolation of an intermediary form of activated prorenin. J Biol Chem 262: 2472-2477, 1987.
22. Dong JM and Sahagian GG. Basis for low affinity binding of a lysosomal cysteine protease to the cation-independent mannose 6-phosphate receptor. J Biol Chem 265: 4210-4217, 1990.
23. Eggena P, Zhu JH, Sereevinyayut S, Giordani M, Clegg K, Andersen PC, Hyun P, and Barrett JD. Hepatic angiotensin II nuclear receptors and transcription of growth-related factors. J Hypertens 14: 961-968, 1996.
24. Ekker M, Tronik D, and Rougeon F. Extra-renal transcription of the renin genes in multiple tissues of mice and rats. Proc Natl Acad Sci USA 86: 5155-5158, 1989.
25. Faust PL, Chirgwin JM, and Kornfeld S. Renin, a secretory glycoprotein, acquires phosphomannosyl residues. J Cell Biol 105: 1947-1955, 1987.
26. Faust PL, Wall DA, Perara E, Lingappa VR, and Kornfeld S. Expression of human cathepsin D in Xenopus oocytes: phosphorylation and intracellular targeting. J Cell Biol 105: 1937-1945, 1987.
27. Haller H, Lindschau C, Erdmann B, Quass P, and Luft FC. Effects of intracellular angiotensin II in vascular smooth muscle cells. Circ Res 79: 765-772, 1996.
28. Heller LJ, Opsahl JA, Wernsing SE, Saxena R, and Katz SA. Myocardial and plasma renin-angiotensinogen dynamics during pressure-induced cardiac hypertrophy. Am J Physiol Regulatory Integrative Comp Physiol 274: R849-R856, 1998.
29. Helseth DL Jr and Veis A. Cathepsin D-mediated processing of procollagen: lysosomal enzyme involvement in secretory processing of procollagen. Proc Natl Acad Sci USA 81: 3302-3306, 1984.
30. Heusser CH, Bews JPA, Alkan SS, Dietrich FM, Wood JM, de Gasparo M, and Hofbauer KG. Monoclonal antibodies to human renin: properties and applications. Clin Exp Hypertens 9: 1259-1275, 1987.
31. Hirsch AT, Opsahl JA, Lunzer MM, and Katz SA. Active renin and angiotensinogen in cardiac interstitial fluid after myocardial infarction. Am J Physiol Heart Circ Physiol 276: H1818-H1826, 1999.
32. 1A receptors. Am J Physiol Renal Physiol 277: F303-F311, 1999.
33. Itskovitz J, Rubattu S, Levron J, and Sealey JE. Highest concentrations of prorenin and human chorionic gonadotropin in gestational sacs during early human pregnancy. J Clin Endocrinol Metab 75: 906-910, 1992.
34. Iwai N and Inagami T. Quantitative analysis of renin gene expression in extrarenal tissues by polymerase chain reaction method. J Hypertens 10: 717-724, 1992.
35. Katz SA, Opsahl JA, Lunzer MM, Forbis LM, and Hirsch AT. Effect of bilateral nephrectomy on active renin, angiotensinogen, and renin glycoforms in plasma and myocardium. Hypertension 30: 259-266, 1997.
36. Khalidi N, McKenzie I, and McKenzie JK. Isoelectric heterogeneity of human prorenin (inactive renin) in body fluids. Am J Hypertens 4: 56-59, 1991.
37. Kim WS, Nakayama K, Nakagawa T, Kawamura Y, Haraguchi K, and Murakami K. Mouse submandibular gland prorenin-converting enzyme is a member of glandular kallikrein family. J Biol Chem 266: 19283-19287, 1991.
38. Kornfeld S. Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors. Annu Rev Biochem 61: 307-330, 1992.
39. Lee SJ and Nathans D. Proliferin secreted by cultured cells binds to mannose 6-phosphate receptors. J Biol Chem 263: 3521-3527, 1988.
40. Lindpaintner K, Jin MW, Niedermaier N, Wilhelm MJ, and Ganten D. Cardiac angiotensinogen and its local activation in the isolated perfused beating heart. Circ Res 67: 564-573, 1990.
41. Lockwood TD. Inactivation of intracellular proteolysis and cathepsin B enzyme activity by dehydroascorbic acid and reactivation by dithiothreitol in perfused rat heart. Biochem Pharmacol 54: 669-675, 1997.
42. Mercure C, Ramla D, Garcia R, Thibault G, Deschepper CF, and Reudelhuber TL. Evidence for intracellular generation of angiotensin II in rat juxtaglomerular cells. FEBS Lett 422: 395-399, 1998.
43. Methot D, Silversides DW, and Reudelhuber TL. In vivo enzymatic assay reveals catalytic activity of the human renin precursor in tissues. Circ Res 84: 1067-1072, 1999.
44. 2-adrenergic receptors to lysosomes during downregulation. J Cell Sci 112: 329-338, 1999.
45. Neves FA, Duncan KG, and Baxter JD. Cathepsin B is a prorenin processing enzyme. Hypertension 27: 514-517, 1996.
46. Nguyen G, Delarue F, Berrou J, Rondeau E, and Sraer JD. Specific receptor binding of renin on human mesangial cells in culture increases plasminogen activator inhibitor-1 antigen. Kidney Int 50: 1897-1903, 1996.
47. Nielsen AH, Mailing C, and Poulsen K. Characteristics and conversion of high molecular weight forms of renin in plasma and their incomplete activation by the current acid treatment. Biochim Biophys Acta 534: 246-257, 1978.
48. Nissley P, Kiess W, and Sklar M. Developmental expression of the IGF-II/mannose 6-phosphate receptor. Mol Reprod Dev 35: 408-413, 1993.
49. Nolly H, Carbini LA, Scicli G, Carretero OA, and Scicli AG. A local kallikrein-kinin system is present in rat hearts. Hypertension 23: 919-923, 1994.
50. Passier RCJJ, Smits JFM, Verluyten MJA, and Daemen MJAP. Expression and localization of renin and angiotensinogen in rat heart after myocardial infarction. Am J Physiol Heart Circ Physiol 271: H1040-H1048, 1996.
51. Reudelhuber TL, Ramla D, Chiu L, Mercure C, and Seidah NG. Proteolytic processing of human prorenin in renal and non-renal tissues. Kidney Int 46: 1522-1524, 1994.
52. Rijnboutt S, Aerts HMFG, Geuze HJ, Tager JM, and Strous GJ. Mannose 6-phosphate-independent membrane association of cathepsin D, glucocerebrosidase, and sphingolipid-activating protein in HepG2 cells. J Biol Chem 266: 4862-4868, 1991.
53. Sealey JE, Catanzaro DF, Lavin TN, Gahnem F, Pitarresi T, Hu LF, and Laragh JH. Specific prorenin/renin binding (ProBP) identification and characterization of a novel membrane site. Am J Hypertens 9: 491-502, 1996.
54. Sealey JE, Goldstein M, Pitarresi T, Kudlak TT, Glorioso N, Fiamengo SA, and Laragh JH. Prorenin secretion from human testis: no evidence for secretion of active renin or angiotensinogen. J Clin Endocrinol Metab 66: 974-978, 1988.
55. Seidah NG, Hamelin J, Gaspar AM, Day R, and Chretien M. The cDNA sequence of the human pro-hormone and proprotein convertase PC1. DNA Cell Biol 11: 283-289, 1992.
56. Sinn PL and Sigmund CD. Transgenic models as tools for studying the regulation of human renin expression. Regul Pept 86: 77-82, 2000.
57. Van Heugten HAA, Bezstarosti K, Dekkers DHW, and Lamers JMJ. Homologous desensitization of the endothelin-1 receptor mediated phosphoinositide response in cultured neonatal rat cardiomyocytes. J Mol Cell Cardiol 25: 41-52, 1993.
58. van Kesteren CAM, Danser AHJ, Derkx FHM, Dekkers DHW, Lamers JMJ, Saxena PR, and Schalekamp MADH. Mannose 6-phosphate receptor-mediated internalization and activation of prorenin by cardiac cells. Hypertension 30: 1389-1396, 1997.
59. van Kesteren CAM, Saris JJ, Dekkers DHW, Lamers JMJ, Saxena PR, Schalekamp MADH, and Danser AHJ. Cultured neonatal rat cardiac myocytes and fibroblasts do not synthesize renin or angiotensinogen: evidence for stretch-induced cardiomyocyte hypertrophy independent of angiotensin II. Cardiovasc Res 43: 148-156, 1999.
60. Zuo WM, Pratt RE, Heusser CH, Bews JPA, de Gasparo MM, and Dzau VJ. Characterization of a monoclonal antibody specific for human active renin. Hypertension 19: 249-254, 1992.