Nucleotide diversity and haplotype structure of the human angiotensinogen gene in two populations

American Journal of Human Genetics

Volumn 70, Issue 1, 2002, Pages 108-123

  Nakajima, Toshiaki ^a   Jorde, Lynn B ^b   Ishigami, Tomoaki ^b,c   Umemura, Satoshi ^c   Emi, Mitsuru ^d   Lalouel, Jean Marc ^b   Inoue, Ituro ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

^c YOKOHAMA CITY UNIVERSITY   (Japan)

^d NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSINOGEN; MICROSATELLITE DNA; NUCLEOTIDE;

ARTICLE; ASIAN; CAUCASIAN; CHIMPANZEE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE MAPPING; GENE MUTATION; GENE SEQUENCE; GENE STRUCTURE; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; HYPERTENSION; NONHUMAN; NORMAL HUMAN; POPULATION GENETICS; PRIORITY JOURNAL; PROMOTER REGION; QUANTITATIVE TRAIT; SINGLE NUCLEOTIDE POLYMORPHISM;

PAN TROGLODYTES;

EID: 0036137018     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/338454     Document Type: Article

References (84)

1. Extent and distribution of linkage disequilibrium in three genomic regions
2. Haplotype analysis of hemochromatosis: Evaluation of different linkage-disequilibrium measures and evolution of disease chromosomes
3. Evaluating loci for use in the genetic analysis of population structure
4. Polymorphism in the angiotensin converting enzyme but not in the angiotensinogen gene is associated with hypertension and type 2 diabetes: The Skaraborg Hypertension and Diabetes Project
5. Haplotypes at ATM identify coding-sequence variation and indicate a region of extensive linkage disequilibrium
6. Drift, admixture, and selection in human evolution: A study with DNA polymorphisms
7. Evaluation of the angiotensinogen locus in human essential hypertension: A European study
8. Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase
9. Genetic epidemiology of single-nucleotide polymorphisms
10. Variations on a theme: Cataloging human DNA sequence variation
11. Molecular genetics of human hypertension: Role of angiotensinogen
12. Seven lessons from two candidate genes in human essential hypertension: Angiotensinogen and epithelial sodium channel
13. A comparison of linkage disequilib measures for fine-scale mapping
14. Human-chimpanzee DNA sequence variation in the four major genes of the renin angiotensin system
15. The extent of linkage disequilibrium in four populations with distinct demographic histories
16. The genetically isolated populations of Finland and Sardinia may not be a panacea for linkage disequilibrium mapping of common disease genes
17. Accuracy of haplotype frequency estimation for biallelic loci, via the expectation-maximization algorithm for unphased diploid genotype data
18. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
19. The diastrophic dysplasia gene encodes a novel sulfate transporter: Positional cloning by fine-structure linkage disequilibrium mapping
20. Human evolution: A start for population genomics
21. Linkage disequilibrium in finite populations
22. A scan for linkage disequilibrium across the human genome
23. A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro
24. Angiotensinogen T174M and M235T variants, sodium intake and hypertension among non-drinking, lean Japanese men and women
25. Multiple sequence alignment with Clustal X
26. Haplotypes of angiotensinogen in essential hypertension
27. Molecular basis of human hypertension: Role of angiotensinogen
28. Linkage disequilibrium as a gene mapping tool
29. Linkage disequilibrium and the search for complex disease genes
30. Using mitochondrial and nuclear DNA markers to reconstruct human evolution
31. Population genomics: A bridge from evolutionary history to genetic medicine
32. Linkage disequilibrium predicts physical distance in the adenomatous polyposis coli region
33. Linkage disequilibrium in the neurofibromatosis 1 region: Implications for gene mapping
34. Comprehensive analysis of the renin-angiotensin gene polymorphisms with relation to hypertension in the Japanese
35. Angiotensinogen gene and essential hypertension in the Japanese: Extensive association study and meta-analysis on six reported studies
36. Haplotypes and linkage disequilibrium at the phenylalanine hydroxylase locus, PAH, in a global representation of populations
37. A global survey of haplotype frequencies and linkage disequilibrium at the DRD2 locus
38. Methods to detect selection in populations with applications to the human
39. Prospects for whole-genome linkage disequilibrium mapping of common disease genes
40. Association between the angiotensinogen 235T-variant and essential hypertension in whites: A systematic review and methodological appraisal
41. Demographic history and linkage disequilibrium in human populations
42. From genetics to mechanism of disease liability
43. Lack of association of 3 functional gene variants with hypertension in African Americans
44. The interaction of selection and linkage. I. General considerations; heterotic models
45. Distribution of gene frequency as a test of the theory of the selective neutrality of polymorphisms
46. Allelic association between marker loci
47. Complex patterns of linkage disequilibrium in the Huntington disease region
48. TOPAL 2.0: Improved detection of mosaic sequences within multiple alignments
49. A graphical method for detecting recombination in phylogenetic data sets
50. Genetic distances between the Utah Mormons and related populations
51. Single nucleotide polymorphism and linkage disequilibrium within the TCR alpha/delta locus
52. Genomic structure and chromosomal mapping of the human site-1 protease (S1P) gene
53. DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene
54. Blood pressure and the T174M and M235T polymorphisms of the angiotensinogen gene
55. Genetic structure of the Utah Mormons: A comparison of results based on DNA, blood groups, migration matrices, isonymy, and pedigrees
56. Genetic structure of the Utah Mormons: A comparison of kinship estimates from DNA, blood groups, genealogies, and ancestral arrays
57. Linkage analysis with candidate genes: The Taiwan young-onset hypertension genetic study
58. The distribution of linkage disequilibrium over anonymous genome regions
59. Linkage disequilibrium in humans: Models and data
60. Lack of association of the angiotensinogen-6 polymorphism with blood pressure levels in the comprehensive NHLBI Family Blood Pressure Program: National Heart, Lung and Blood Institute
61. AGT M235T and ACE ID polymorphisms and exercise blood pressure in the HERITAGE Family Study
62. Linkage disequilibrium in the human genome
63. Genome-wide linkage analysis of systolic and diastolic blood pressure: The Quebec Family Study
64. Searching for genetic determinants in the new millennium
65. The future of genetic studies of complex human diseases
66. A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms
67. Nine polymorphisms of angiotensinogen gene in the susceptibility to essential hypertension
68. The future of genetic case-control studies
69. M235T angiotensinogen gene polymorphism and cardiovascular renal risk
70. Haplotype variation and linkage disequilibrium in 313 human genes
71. Juxtaposed regions of extensive and minimal linkage disequilibrium in human Xq25 and Xq28
72. Angiotensin converting enzyme gene insertion/deletion polymorphism, angiotensinogen gene polymorphisms, family history of hypertension, and childhood blood pressure
73. Recombinational and mutational hotspots within the human lipoprotein lipase gene
74. Linkage disequilibrium mapping of complex disease: Fantasy or reality?
75. Global patterns of linkage disequilibrium at the CD4 locus and modern human origins
76. A global haplotype analysis of the myotonic dystrophy locus: Implications for the evolution of modern humans and for the origin of myotonic dystrophy mutations
77. The accuracy of statistical methods for estimation of haplotype frequencies: An example from the CD4 locus
78. Short tandem-repeat polymorphism/Alu haplotype variation at the PLAT locus: Implications for modern human origins
79. Y chromosome sequence variation and the history of human populations
80. When did the human population size start increasing?
81. The power of linkage detection by the transmission/disequilibrium tests
82. Comparison of human genetic and sequence-based physical maps
83. Major factors influencing linkage disequilibrium by analysis of different chromosome regions in distinct populations: Demography, chromosome recombination frequency and selection