메뉴 건너뛰기




Volumn 40, Issue 5, 2002, Pages 687-693

Antiinflammatory and antiarteriosclerotic effects of pioglitazone

Author keywords

Arteriosclerosis; Leukocytes; Nitric oxide; Remodeling

Indexed keywords

CHEMOKINE RECEPTOR CCR2; MONOCYTE CHEMOTACTIC PROTEIN 1; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; OLMESARTAN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE;

EID: 0036842574     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000036396.64769.C2     Document Type: Article
Times cited : (149)

References (38)
  • 1
    • 0032560807 scopus 로고    scopus 로고
    • Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction
    • Haffner SM, Lehto S, Ronnemaa T, Pyorala K, Laakso M. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med. 1998;339:229-234.
    • (1998) N Engl J Med , vol.339 , pp. 229-234
    • Haffner, S.M.1    Lehto, S.2    Ronnemaa, T.3    Pyorala, K.4    Laakso, M.5
  • 2
    • 0035432974 scopus 로고    scopus 로고
    • Impact of diabetes on long-term survival after acute myocardial infarction: Comparability of risk with prior myocardial infarction
    • Mukamal KJ, Nesto RW, Cohen MC, Muller JE, Maclure M, Sherwood JB, Mittleman MA. Impact of diabetes on long-term survival after acute myocardial infarction: Comparability of risk with prior myocardial infarction. Diabetes Care. 2001;24:1422-1427.
    • (2001) Diabetes Care , vol.24 , pp. 1422-1427
    • Mukamal, K.J.1    Nesto, R.W.2    Cohen, M.C.3    Muller, J.E.4    Maclure, M.5    Sherwood, J.B.6    Mittleman, M.A.7
  • 4
    • 0032560545 scopus 로고    scopus 로고
    • Expression of the peroxisome proliferator-activated receptor-γ (PPARγ) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein
    • Ricote M, Huang J, Fajas L, Li A, Welch J, Najib J, Witztum JL, Auwerx J, Palinski W, Glass CK. Expression of the peroxisome proliferator-activated receptor-γ (PPARγ) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein. Proc Natl Acad Sci U S A. 1998;95:7614-7619.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 7614-7619
    • Ricote, M.1    Huang, J.2    Fajas, L.3    Li, A.4    Welch, J.5    Najib, J.6    Witztum, J.L.7    Auwerx, J.8    Palinski, W.9    Glass, C.K.10
  • 5
    • 0033605677 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ ligands are potent inhibitors of angiogenesis in vitro and in vivo
    • Xin X, Yang S, Kowalski J, Gerritsen ME. Peroxisome proliferator-activated receptor-γ ligands are potent inhibitors of angiogenesis in vitro and in vivo. J Biol Chem. 1999;274:9116-9121.
    • (1999) J Biol Chem , vol.274 , pp. 9116-9121
    • Xin, X.1    Yang, S.2    Kowalski, J.3    Gerritsen, M.E.4
  • 7
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
    • Jiang C, Ting AT, Seed B. PPAR-γ agonists inhibit production of monocyte inflammatory cytokines. Nature. 1998;391:82-86.
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 8
    • 0344333464 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ activators inhibit gene expression and migration in human vascular smooth muscle cells
    • Marx N, Schonbeck U, Lazar MA, Libby P, Plutzky J. Peroxisome proliferator-activated receptor-γ activators inhibit gene expression and migration in human vascular smooth muscle cells. Circ Res. 1998;83:1097-1103.
    • (1998) Circ Res , vol.83 , pp. 1097-1103
    • Marx, N.1    Schonbeck, U.2    Lazar, M.A.3    Libby, P.4    Plutzky, J.5
  • 9
    • 0034711678 scopus 로고    scopus 로고
    • Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-γ activators
    • Pasceri V, Wu HD, Willerson JT, Yeh ET. Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-γ activators. Circulation. 2000;101:235-238.
    • (2000) Circulation , vol.101 , pp. 235-238
    • Pasceri, V.1    Wu, H.D.2    Willerson, J.T.3    Yeh, E.T.4
  • 10
    • 0001538199 scopus 로고    scopus 로고
    • Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator-activated receptor-γ
    • Han KH, Chang MK, Boullier A, Green SR, Li A, Glass CK, Quehenberger O. Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator-activated receptor-γ. J Clin Invest. 2000;106:793-802.
    • (2000) J Clin Invest , vol.106 , pp. 793-802
    • Han, K.H.1    Chang, M.K.2    Boullier, A.3    Green, S.R.4    Li, A.5    Glass, C.K.6    Quehenberger, O.7
  • 14
    • 0035201123 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ ligands inhibit nuclear but not cytosolic extracellular signal-regulated kinase/mitogen-activated protein kinase-regulated steps in vascular smooth muscle cell migration
    • Goetze S, Kintscher U, Kim S, Meehan WP, Kaneshiro K, Collins AR, Fleck E, Hsueh WA, Law RE. Peroxisome proliferator-activated receptor-γ ligands inhibit nuclear but not cytosolic extracellular signal-regulated kinase/mitogen-activated protein kinase-regulated steps in vascular smooth muscle cell migration. J Cardiovasc Pharmacol. 2001;38:909-921.
    • (2001) J Cardiovasc Pharmacol , vol.38 , pp. 909-921
    • Goetze, S.1    Kintscher, U.2    Kim, S.3    Meehan, W.P.4    Kaneshiro, K.5    Collins, A.R.6    Fleck, E.7    Hsueh, W.A.8    Law, R.E.9
  • 15
    • 0034332862 scopus 로고    scopus 로고
    • Troglitazone reduces neointimal tissue proliferation after coronary stent implantation in patients with non-insulin dependent diabetes mellitus: A serial intravascular ultrasound study
    • Takagi T, Akasaka T, Yamamuro A, Honda Y, Hozumi T, Morioka S, Yoshida K. Troglitazone reduces neointimal tissue proliferation after coronary stent implantation in patients with non-insulin dependent diabetes mellitus: A serial intravascular ultrasound study. J Am Coll Cardiol. 2000;36:1529-1535.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 1529-1535
    • Takagi, T.1    Akasaka, T.2    Yamamuro, A.3    Honda, Y.4    Hozumi, T.5    Morioka, S.6    Yoshida, K.7
  • 16
    • 0033542091 scopus 로고    scopus 로고
    • Thiazolidinediones down-regulate plasminogen activator inhibitor type 1 expression in human vascular endothelial cells: A possible role for PPARγ in endothelial function
    • Kato K, Satoh H, Endo Y, Yamada D, Midorikawa S, Sato W, Mizuno K, Fujita T, Tsukamoto K, Watanabe T. Thiazolidinediones down-regulate plasminogen activator inhibitor type 1 expression in human vascular endothelial cells: A possible role for PPARγ in endothelial function. Biochem Biophys Res Commun. 1999;258:431-435.
    • (1999) Biochem Biophys Res Commun , vol.258 , pp. 431-435
    • Kato, K.1    Satoh, H.2    Endo, Y.3    Yamada, D.4    Midorikawa, S.5    Sato, W.6    Mizuno, K.7    Fujita, T.8    Tsukamoto, K.9    Watanabe, T.10
  • 17
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ
    • Nagy L, Tontonoz P, Alvarez JG, Chen H, Evans RM. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ. Cell. 1998;93:229-240.
    • (1998) Cell , vol.93 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.3    Chen, H.4    Evans, R.M.5
  • 18
    • 0032540012 scopus 로고    scopus 로고
    • PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL
    • Tontonoz P, Nagy L, Alvarez JG, Thomazy VA, Evans RM, PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell. 1998;93:241-252.
    • (1998) Cell , vol.93 , pp. 241-252
    • Tontonoz, P.1    Nagy, L.2    Alvarez, J.G.3    Thomazy, V.A.4    Evans, R.M.5
  • 19
    • 0031029539 scopus 로고    scopus 로고
    • Important role of tissue angiotensin-converting enzyme activity in the pathogenesis of coronary vascular and myocardial structural changes induced by long-term blockade of nitric oxide synthesis in rats
    • Takemoto M, Egashira K, Usui M, Numaguchi K, Tomita H, Tsutsui H, Shimokawa H, Sueishi K, Takeshita A. Important role of tissue angiotensin-converting enzyme activity in the pathogenesis of coronary vascular and myocardial structural changes induced by long-term blockade of nitric oxide synthesis in rats. J Clin Invest. 1997;99:278-287.
    • (1997) J Clin Invest , vol.99 , pp. 278-287
    • Takemoto, M.1    Egashira, K.2    Usui, M.3    Numaguchi, K.4    Tomita, H.5    Tsutsui, H.6    Shimokawa, H.7    Sueishi, K.8    Takeshita, A.9
  • 21
    • 0032487326 scopus 로고    scopus 로고
    • Cardiac angiotensin II receptors are upregulated by long-term inhibition of nitric oxide synthesis in rats
    • Katoh M, Egashira K, Usui M, Ichiki T, Tomita H, Shimokawa H, Rakugi H, Takeshita A. Cardiac angiotensin II receptors are upregulated by long-term inhibition of nitric oxide synthesis in rats. Circ Res. 1998;83:743-751.
    • (1998) Circ Res , vol.83 , pp. 743-751
    • Katoh, M.1    Egashira, K.2    Usui, M.3    Ichiki, T.4    Tomita, H.5    Shimokawa, H.6    Rakugi, H.7    Takeshita, A.8
  • 22
    • 0034711717 scopus 로고    scopus 로고
    • Important role of local angiotensin II activity mediated via type 1 receptor in the pathogenesis of cardiovascular inflammatory changes induced by chronic blockade of nitric oxide synthesis in rats
    • Usui M, Egashira K, Tomita H, Koyanagi M, Katoh M, Shimokawa H, Takeya M, Yoshimura T, Matsushima K, Takeshita A. Important role of local angiotensin II activity mediated via type 1 receptor in the pathogenesis of cardiovascular inflammatory changes induced by chronic blockade of nitric oxide synthesis in rats. Circulation. 2000;101:305-310.
    • (2000) Circulation , vol.101 , pp. 305-310
    • Usui, M.1    Egashira, K.2    Tomita, H.3    Koyanagi, M.4    Katoh, M.5    Shimokawa, H.6    Takeya, M.7    Yoshimura, T.8    Matsushima, K.9    Takeshita, A.10
  • 24
    • 0034739484 scopus 로고    scopus 로고
    • Role of monocyte chemoattractant protein-1 in cardiovascular remodeling induced by chronic blockade of nitric oxide synthesis
    • Koyanagi M, Egashira K, Kitamoto S, Ni W, Shimokawa H, Takeya M, Yoshimura T, Takeshita A. Role of monocyte chemoattractant protein-1 in cardiovascular remodeling induced by chronic blockade of nitric oxide synthesis. Circulation. 2000;102:2243-2248.
    • (2000) Circulation , vol.102 , pp. 2243-2248
    • Koyanagi, M.1    Egashira, K.2    Kitamoto, S.3    Ni, W.4    Shimokawa, H.5    Takeya, M.6    Yoshimura, T.7    Takeshita, A.8
  • 25
    • 0030717697 scopus 로고    scopus 로고
    • Chronic angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade: Effects on cardiovascular remodeling in rats induced by the long-term blockade of nitric oxide synthesis
    • Takemoto M, Egashira K, Tomita H, Usui M, Okamoto H, Kitabatake A, Shimokawa H, Sueishi K, Takeshita A. Chronic angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade: Effects on cardiovascular remodeling in rats induced by the long-term blockade of nitric oxide synthesis. Hypertension. 1997;30:1621-1627.
    • (1997) Hypertension , vol.30 , pp. 1621-1627
    • Takemoto, M.1    Egashira, K.2    Tomita, H.3    Usui, M.4    Okamoto, H.5    Kitabatake, A.6    Shimokawa, H.7    Sueishi, K.8    Takeshita, A.9
  • 26
    • 0029893069 scopus 로고    scopus 로고
    • Simultaneous quantitation of pioglitazone and its metabolites in human serum by liquid chromatography and solid phase extraction
    • Zhong WZ, Williams MG. Simultaneous quantitation of pioglitazone and its metabolites in human serum by liquid chromatography and solid phase extraction. J Pharm Biomed Anal. 1996;14:465-473.
    • (1996) J Pharm Biomed Anal , vol.14 , pp. 465-473
    • Zhong, W.Z.1    Williams, M.G.2
  • 27
    • 0035980169 scopus 로고    scopus 로고
    • Antiinflammatory and antiarteriosclerotic actions of HMG-CoA reductase inhibitors in a rat model of chronic inhibition of nitric oxide synthesis
    • Ni W, Egashira K, Kataoka C, Kitamoto S, Koyanagi M, Inoue S, Takeshita A. Antiinflammatory and antiarteriosclerotic actions of HMG-CoA reductase inhibitors in a rat model of chronic inhibition of nitric oxide synthesis. Circ Res. 2001;89:415-421.
    • (2001) Circ Res , vol.89 , pp. 415-421
    • Ni, W.1    Egashira, K.2    Kataoka, C.3    Kitamoto, S.4    Koyanagi, M.5    Inoue, S.6    Takeshita, A.7
  • 29
    • 0035936802 scopus 로고    scopus 로고
    • Atherosclerosis: The road ahead
    • Glass CK, Witztum JL. Atherosclerosis: The road ahead. Cell. 2001;104:503-516.
    • (2001) Cell , vol.104 , pp. 503-516
    • Glass, C.K.1    Witztum, J.L.2
  • 30
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis AJ. Atherosclerosis. Nature. 2000;407:233-241.
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 31
    • 0032572719 scopus 로고    scopus 로고
    • -/- mice reveals a role for chemokines in the initiation of atherosclerosis
    • -/- mice reveals a role for chemokines in the initiation of atherosclerosis. Nature. 1998;394:894-897.
    • (1998) Nature , vol.394 , pp. 894-897
    • Boring, L.1    Gosling, J.2    Cleary, M.3    Charo, I.F.4
  • 32
    • 0035396489 scopus 로고    scopus 로고
    • Homocysteine stimulates the expression of monocyte chemoattractant protein-1 receptor (CCR2) in human monocytes: Possible involvement of oxygen free radicals
    • Wang G, O K. Homocysteine stimulates the expression of monocyte chemoattractant protein-1 receptor (CCR2) in human monocytes: Possible involvement of oxygen free radicals. Biochem J. 2001;357:233-240.
    • (2001) Biochem J , vol.357 , pp. 233-240
    • Wang, G.1    O, K.2
  • 33
    • 0029823037 scopus 로고    scopus 로고
    • Increased accumulation of tissue ACE in human atherosclerotic coronary artery disease
    • Diet F, Pratt RE, Berry GJ, Momose N, Gibbons GH, Dzau VJ. Increased accumulation of tissue ACE in human atherosclerotic coronary artery disease. Circulation. 1996;94:2756-2767.
    • (1996) Circulation , vol.94 , pp. 2756-2767
    • Diet, F.1    Pratt, R.E.2    Berry, G.J.3    Momose, N.4    Gibbons, G.H.5    Dzau, V.J.6
  • 36
    • 0035048905 scopus 로고    scopus 로고
    • Tissue angiotensin and pathobiology of vascular disease: A unifying hypothesis
    • Dzau VJ. Tissue angiotensin and pathobiology of vascular disease: A unifying hypothesis. Hypertension. 2001;37:1047-1052.
    • (2001) Hypertension , vol.37 , pp. 1047-1052
    • Dzau, V.J.1
  • 37
    • 0032749870 scopus 로고    scopus 로고
    • Pathogenic role of oxidative stress in vascular angiotensin-converting enzyme activation in long-term blockade of nitric oxide synthesis in rats
    • Usui M, Egashira K, Kitamoto S, Koyanagi M, Katoh M, Kataoka C, Shimokawa H, Takeshita A. Pathogenic role of oxidative stress in vascular angiotensin-converting enzyme activation in long-term blockade of nitric oxide synthesis in rats. Hypertension. 1999;34:546-551.
    • (1999) Hypertension , vol.34 , pp. 546-551
    • Usui, M.1    Egashira, K.2    Kitamoto, S.3    Koyanagi, M.4    Katoh, M.5    Kataoka, C.6    Shimokawa, H.7    Takeshita, A.8
  • 38
    • 0035132330 scopus 로고    scopus 로고
    • PPAR-γ-dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
    • Chawla A, Barak Y, Nagy L, Liao D, Tontonoz P, Evans RM. PPAR-γ-dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nat Med. 2001;7:48-52.
    • (2001) Nat Med , vol.7 , pp. 48-52
    • Chawla, A.1    Barak, Y.2    Nagy, L.3    Liao, D.4    Tontonoz, P.5    Evans, R.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.