Cardiovascular effects of prorenin blockade in genetically spontaneously hypertensive rats on normal and high-salt diet

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 295, Issue 3, 2008, Pages

  Susic, Dinko ^a   Zhou, Xiaoyan ^a   Frohlich, Edward D ^a   Lippton, Howard ^b   Knight, Martha ^b  

^a OCHSNER CLINIC FOUNDATION   (United States)

^b Pneumosite Limited Liability Company   (United States)

Author keywords

Left ventricular function; Myocardial fibrosis; Prorenin inhibitor; Proteinuria; Renin

Indexed keywords

ARGINYLISOLEUCYLLEUCYLLEUCYLLYSYLLYSYLMETHIONYLPROLYLSERYLVALINE; CARDIOVASCULAR AGENT; CREATININE; PRORENIN; SODIUM CHLORIDE; UNCLASSIFIED DRUG; CREATINE; RENIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; CARDIOVASCULAR EFFECT; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG MECHANISM; ESSENTIAL HYPERTENSION; EXPERIMENTAL MODEL; HEART INJURY; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE MASS; HEART MUSCLE FIBROSIS; HEART VENTRICLE FUNCTION; KIDNEY FUNCTION; KIDNEY INJURY; MALE; MALIGNANT HYPERTENSION; NONHUMAN; OSMOTIC MINIPUMP; PATHOGENESIS; PRIORITY JOURNAL; RAT; SALT INTAKE; SPONTANEOUSLY HYPERTENSIVE RAT; TARGET ORGAN; AMINO ACID SEQUENCE; ANIMAL; BLOOD; BLOOD PRESSURE; CARDIOVASCULAR FUNCTION; DIET; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HEART LEFT VENTRICLE HYPERTROPHY; HEART RATE; HEART RIGHT VENTRICLE HYPERTROPHY; HYPERTENSION; MOLECULAR GENETICS; PATHOPHYSIOLOGY; PHYSIOLOGY; SODIUM INTAKE; URODYNAMICS;

AMINO ACID SEQUENCE; ANIMALS; BLOOD PRESSURE; CARDIOVASCULAR PHYSIOLOGY; CREATINE; DIET; HEART RATE; HYPERTENSION; HYPERTROPHY, LEFT VENTRICULAR; HYPERTROPHY, RIGHT VENTRICULAR; MALE; MOLECULAR SEQUENCE DATA; RATS; RATS, INBRED SHR; RENIN; SODIUM, DIETARY; URODYNAMICS; VENTRICULAR FUNCTION, LEFT;

EID: 54049106595     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00055.2008     Document Type: Article

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