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Volumn 97, Issue 7, 1996, Pages 1715-1722

Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion

Author keywords

endothelial cells; I B; macrophages; p65; smooth muscle cells

Indexed keywords

DNA BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR PROTEIN; MONOCLONAL ANTIBODY; TRANSCRIPTION FACTOR;

EID: 13344261982     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118598     Document Type: Article
Times cited : (728)

References (51)
  • 1
    • 0024475227 scopus 로고
    • NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control
    • Lenardo, M.J., and D Baltimore. 1989. NF-κB: a pleiotropic mediator of inducible and tissue-specific gene control. Cell 58:227-229.
    • (1989) Cell , vol.58 , pp. 227-229
    • Lenardo, M.J.1    Baltimore, D.2
  • 2
    • 0025865317 scopus 로고
    • The inducible transcription activator NF-κB: Regulation by distinct protein subunits
    • Baeuerle, P.A. 1991. The inducible transcription activator NF-κB: regulation by distinct protein subunits. Biochim. Biophys Acta 1072:63-80.
    • (1991) Biochim. Biophys Acta , vol.1072 , pp. 63-80
    • Baeuerle, P.A.1
  • 3
    • 0027232067 scopus 로고
    • NF-κB and Rel: Participants in a multiform transcriptional regulatory system
    • Grilli, M., J.J.-S. Chiu, and M.J. Lenardo. 1993. NF-κB and Rel: participants in a multiform transcriptional regulatory system. Int. Rev. Cytol 143:1-62.
    • (1993) Int. Rev. Cytol , vol.143 , pp. 1-62
    • Grilli, M.1    Chiu, J.J.-S.2    Lenardo, M.J.3
  • 4
    • 0028174061 scopus 로고
    • Function and activation of NF-κB in the immune system
    • Baeuerle, P.A., and T. Henkel. 1994. Function and activation of NF-κB in the immune system. Annu. Rev. Immunol 12:141-179.
    • (1994) Annu. Rev. Immunol , vol.12 , pp. 141-179
    • Baeuerle, P.A.1    Henkel, T.2
  • 5
    • 0023724778 scopus 로고
    • IκB: A specific inhibitor of the NF-κB transcription factor
    • Baeuerle, P.A., and D. Baltimore 1988. IκB: a specific inhibitor of the NF-κB transcription factor. Science (Wash. DC) 242:540-546.
    • (1988) Science (Wash. DC) , vol.242 , pp. 540-546
    • Baeuerle, P.A.1    Baltimore, D.2
  • 7
    • 0027264083 scopus 로고
    • Nuclear factor kappa B, a mediator of lipopolysaccharide effects
    • Muller, J M , H.W.L. Ziegler-Heitbrock, and P A. Baeuerle. 1993 Nuclear factor kappa B, a mediator of lipopolysaccharide effects Immunobiology. 187. 233-256.
    • (1993) Immunobiology , vol.187 , pp. 233-256
    • Muller, J.M.1    Ziegler-Heitbrock, H.W.L.2    Baeuerle, P.A.3
  • 8
    • 0026333959 scopus 로고
    • Role of oxidized low density lipoprotein in atherogenesis
    • Witztum, J.L., and D. Steinberg. 1991. Role of oxidized low density lipoprotein in atherogenesis. J. Clin. Invest. 88:1785-1792.
    • (1991) J. Clin. Invest. , vol.88 , pp. 1785-1792
    • Witztum, J.L.1    Steinberg, D.2
  • 10
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990s
    • Ross, R. 1993. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature (Lond.). 362:801-809.
    • (1993) Nature (Lond.). , vol.362 , pp. 801-809
    • Ross, R.1
  • 11
    • 0027193894 scopus 로고
    • Endothelial nuclear factor-κB and the initiation of the atherosclerotic lesion
    • Collins. T. 1993. Endothelial nuclear factor-κB and the initiation of the atherosclerotic lesion. Lab. Invest. 68:499-508.
    • (1993) Lab. Invest. , vol.68 , pp. 499-508
    • Collins, T.1
  • 12
    • 0028073962 scopus 로고
    • Fibronectin attachment activates the NF-κB p50/p65 heterodimer in fibroblasts and smooth muscle cells
    • Qwarnström, E.E., C.O. Ostberg, G.L. Turk, C.A. Richardson, and K. Bomsztyk. 1994. Fibronectin attachment activates the NF-κB p50/p65 heterodimer in fibroblasts and smooth muscle cells. J. Biol. Chem. 269:30765-30768.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30765-30768
    • Qwarnström, E.E.1    Ostberg, C.O.2    Turk, G.L.3    Richardson, C.A.4    Bomsztyk, K.5
  • 13
    • 0023019596 scopus 로고
    • Human atherosclerosis. II. Immunocytochemical analysis of the cellular composition of human atherosclerotic lesions
    • Gown, A.M., T. Tsukada, and R. Ross. 1986. Human atherosclerosis. II. Immunocytochemical analysis of the cellular composition of human atherosclerotic lesions Am. J. Pathol. 125:191-207.
    • (1986) Am. J. Pathol. , vol.125 , pp. 191-207
    • Gown, A.M.1    Tsukada, T.2    Ross, R.3
  • 14
    • 0025171289 scopus 로고
    • Tumor necrosis factor gene expression in human vascular smooth muscle cells detected by in vitro hybridization
    • Barath, P., M.C. Fishbein, J. Lao, J Bernson, R.H Helfaut, and J.S. Forrester 1990. Tumor necrosis factor gene expression in human vascular smooth muscle cells detected by in vitro hybridization. Am. J Pathol. 137.503-509.
    • (1990) Am. J Pathol. , vol.137 , pp. 503-509
    • Barath, P.1    Fishbein, M.C.2    Lao, J.3    Bernson, J.4    Helfaut, R.H.5    Forrester, J.S.6
  • 15
    • 0028058848 scopus 로고
    • An evolutionary and functional approach to the TNF receptor/ligand family
    • Beutler, B., and C. van Huffel 1994. An evolutionary and functional approach to the TNF receptor/ligand family. Ann NY Acad. Sci. 730:118-133.
    • (1994) Ann NY Acad. Sci. , vol.730 , pp. 118-133
    • Beutler, B.1    Van Huffel, C.2
  • 17
    • 0026514827 scopus 로고
    • Macrophage colony-stimmulatuig factor mRNA and protein in atherosclerotic lesions of rabbits and humans
    • Rosenfeld, M.E., S Yla-Herttuala, B.A. Lipton, V.A. Ord, J.L. Witztum, and D. Steinberg. 1992. Macrophage colony-stimmulatuig factor mRNA and protein in atherosclerotic lesions of rabbits and humans. Am. J. Pathol. 140: 291-300.
    • (1992) Am. J. Pathol. , vol.140 , pp. 291-300
    • Rosenfeld, M.E.1    Yla-Herttuala, S.2    Lipton, B.A.3    Ord, V.A.4    Witztum, J.L.5    Steinberg, D.6
  • 18
    • 0026536343 scopus 로고
    • Macrophage colony-stimulating factor gene expression in vascular cells and in experimental and human atherosclerosis
    • Clinton, S.K., R. Underwood, L. Haynes, M.L. Sherman, D.W. Kufe, and P. Libby. 1992. Macrophage colony-stimulating factor gene expression in vascular cells and in experimental and human atherosclerosis. Am. J. Pathol. 140:301-316.
    • (1992) Am. J. Pathol. , vol.140 , pp. 301-316
    • Clinton, S.K.1    Underwood, R.2    Haynes, L.3    Sherman, M.L.4    Kufe, D.W.5    Libby, P.6
  • 20
    • 0001495165 scopus 로고
    • Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque
    • Wilcox, J.N., K.M. Smith, S.M. Schwartz, and D. Gordon. 1989. Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque. Proc. Natl Acad. Sci. USA. 86:2839-2843.
    • (1989) Proc. Natl Acad. Sci. USA. , vol.86 , pp. 2839-2843
    • Wilcox, J.N.1    Smith, K.M.2    Schwartz, S.M.3    Gordon, D.4
  • 21
    • 0025776417 scopus 로고
    • Tissue factor mRNA in THP-1 monocytic cells is regulated at both transcriptional and posttranscriptional levels in response to lipopolysaccharide
    • Brand, K., B.J. Fowler, T.S. Edgington, and N. Mackman. 1991. Tissue factor mRNA in THP-1 monocytic cells is regulated at both transcriptional and posttranscriptional levels in response to lipopolysaccharide. Mol. Cell. Biol. 11: 4732-4738.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 4732-4738
    • Brand, K.1    Fowler, B.J.2    Edgington, T.S.3    Mackman, N.4
  • 22
    • 0025720571 scopus 로고
    • Lipopolysaccharide-mediated transcriptional activation of the human tissue factor gene in THP-1 monocytic cells requires both activator protein 1 and nuclear factor κB binding sites
    • Mackman, N., K. Brand, and T.S. Edgington. 1991 Lipopolysaccharide-mediated transcriptional activation of the human tissue factor gene in THP-1 monocytic cells requires both activator protein 1 and nuclear factor κB binding sites. J Exp Med. 174.1517-1526.
    • (1991) J Exp Med. , vol.174 , pp. 1517-1526
    • Mackman, N.1    Brand, K.2    Edgington, T.S.3
  • 23
    • 0025875990 scopus 로고
    • The structural biology of expression and function of tissue factor
    • Edgington, T.S., N Mackman, K. Brand, and W. Ruf. 1994. The structural biology of expression and function of tissue factor. Thromb. Haemost. 66: 67-79.
    • (1994) Thromb. Haemost. , vol.66 , pp. 67-79
    • Edgington, T.S.1    Mackman, N.2    Brand, K.3    Ruf, W.4
  • 24
    • 0025896795 scopus 로고
    • Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis
    • Cybulsky, M.I., and M.A. Gimbrone, Jr. 1991. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science (Wash DC). 251:788-791.
    • (1991) Science (Wash DC). , vol.251 , pp. 788-791
    • Cybulsky, M.I.1    Gimbrone Jr., M.A.2
  • 25
    • 0026490278 scopus 로고
    • Functional analysis of the human vascular cell adhesion molecule-1 promotor
    • Neish, A.S , A J. Williams, H.J. Palmer, M.Z. Whitley, and T. Collins. 1992. Functional analysis of the human vascular cell adhesion molecule-1 promotor. J Exp. Med. 176:1583-1593.
    • (1992) J Exp. Med. , vol.176 , pp. 1583-1593
    • Neish, A.S.1    Williams, A.J.2    Palmer, H.J.3    Whitley, M.Z.4    Collins, T.5
  • 26
    • 0026672245 scopus 로고
    • Characterization of the promotor for vascular cell adhesion molecule-1 (VCAM-1)
    • Iademarco, M.F., J J. McQuillan, G.D. Rosen, and D.C. Dean. 1992 Characterization of the promotor for vascular cell adhesion molecule-1 (VCAM-1). J. Biol Chem. 267:16323-16329.
    • (1992) J. Biol Chem. , vol.267 , pp. 16323-16329
    • Iademarco, M.F.1    McQuillan, J.J.2    Rosen, G.D.3    Dean, D.C.4
  • 28
    • 0025302552 scopus 로고
    • Interaction of an NF-κB like factor with a site upstream of the c-myc promotor
    • Duyao, M.P., A.J Buckler, and G.E Sonenshein. 1990 Interaction of an NF-κB like factor with a site upstream of the c-myc promotor. Proc. Natl. Acad. Sci. USA. 87:4727-4731.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 4727-4731
    • Duyao, M.P.1    Buckler, A.J.2    Sonenshein, G.E.3
  • 29
    • 0027170699 scopus 로고
    • Minimally modified low density lipoprotein-induced inflammatory responses in endothelial cells are mediated by cyclic adenosine monophosphate
    • Parhami, F., Z.T. Fang, A.M. Fogelman, A Andalibi, M.C. Territo, and J.A Berliner. 1993. Minimally modified low density lipoprotein-induced inflammatory responses in endothelial cells are mediated by cyclic adenosine monophosphate. J. Clin. Invest. 92:471-478.
    • (1993) J. Clin. Invest. , vol.92 , pp. 471-478
    • Parhami, F.1    Fang, Z.T.2    Fogelman, A.M.3    Andalibi, A.4    Territo, M.C.5    Berliner, J.A.6
  • 30
    • 0028047925 scopus 로고
    • Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice
    • Liao, F., A. Andalibi, J.-H. Qiao, H Allayee, A.M. Fogelman, and A.J. Lusis 1994. Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice. J. Clin Invest. 94:877-884.
    • (1994) J. Clin Invest. , vol.94 , pp. 877-884
    • Liao, F.1    Andalibi, A.2    Qiao, J.-H.3    Allayee, H.4    Fogelman, A.M.5    Lusis, A.J.6
  • 31
    • 0025231361 scopus 로고
    • Induction of endothelial cell expression of granulocyte and macrophage colony-stimulating factors by modified low density lipoproteins
    • Rajavashisth, T.B., A. Andalibi, M.C. Territo, J.A. Berliner, M. Navab, A.M. Fogelman, and A.J. Lusis. 1990. Induction of endothelial cell expression of granulocyte and macrophage colony-stimulating factors by modified low density lipoproteins. Nature (Lond.) 344.254-257.
    • (1990) Nature (Lond.) , vol.344 , pp. 254-257
    • Rajavashisth, T.B.1    Andalibi, A.2    Territo, M.C.3    Berliner, J.A.4    Navab, M.5    Fogelman, A.M.6    Lusis, A.J.7
  • 32
    • 0025214424 scopus 로고
    • Oxidized low density lipoprotein suppresses the expression of tumor necrosis factor-α mRNA in stimulated murine peritoneal macrophages
    • Hamilton, T.A , G. Ma, and G.M. Chisholm 1990. Oxidized low density lipoprotein suppresses the expression of tumor necrosis factor-α mRNA in stimulated murine peritoneal macrophages. J. Immunol. 144:2343-2350.
    • (1990) J. Immunol. , vol.144 , pp. 2343-2350
    • Hamilton, T.A.1    Ma, G.2    Chisholm, G.M.3
  • 33
    • 0026347097 scopus 로고
    • Inhibition of lipopolysaccharide-induced interleukin-1β mRNA expression in mouse macrophages by oxidized low density lipoprotein
    • Fong, L.G., T.A.T. Fong, and A.D. Cooper. 1991. Inhibition of lipopolysaccharide-induced interleukin-1β mRNA expression in mouse macrophages by oxidized low density lipoprotein J Lipid Res. 32.1899-1910.
    • (1991) J Lipid Res. , vol.32 , pp. 1899-1910
    • Fong, L.G.1    Fong, T.A.T.2    Cooper, A.D.3
  • 34
    • 0028214529 scopus 로고
    • Oxidized low density lipoprotein enhances lipopolysaccharide-induced tissue factor expression in human adherent monocytes
    • Brand, K., C L. Banca, N Mackman, R.A. Terkeltaub, S T. Fan and L.K. Curtiss 1994. Oxidized low density lipoprotein enhances lipopolysaccharide-induced tissue factor expression in human adherent monocytes. Arterioscler. Thromb. 14:790-797.
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 790-797
    • Brand, K.1    Banca, C.L.2    Mackman, N.3    Terkeltaub, R.A.4    Fan, S.T.5    Curtiss, L.K.6
  • 35
    • 0028177460 scopus 로고
    • Oxidized LDL induces monocytic cell expression of interleukin-8, a chemokine with T-lymphocyte chemotactic activity
    • Terkeltaub, R., C.L Banca, J. Solan, D. Santoro, K Brand, and L K Curtiss. 1994. Oxidized LDL induces monocytic cell expression of interleukin-8, a chemokine with T-lymphocyte chemotactic activity. Arterioscler. Thromb. 14:47-53.
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 47-53
    • Terkeltaub, R.1    Banca, C.L.2    Solan, J.3    Santoro, D.4    Brand, K.5    Curtiss, L.K.6
  • 39
    • 0022469165 scopus 로고
    • A light and electron microscopic procedure for sequential double antigen localization using diaminobenzidine and benzidine dihydrochloride
    • Levey, A.I., J.P. Bolam, D.B. Rye, A.E. Hallanger, R.M. Demuth, M -M. Mesulam, and B.H. Wainer. 1986. A light and electron microscopic procedure for sequential double antigen localization using diaminobenzidine and benzidine dihydrochloride. J. Histochem. Cytochem. 34:1449-1457.
    • (1986) J. Histochem. Cytochem. , vol.34 , pp. 1449-1457
    • Levey, A.I.1    Bolam, J.P.2    Rye, D.B.3    Hallanger, A.E.4    Demuth, R.M.5    Mesulam, M.M.6    Wainer, B.H.7
  • 40
    • 0025348257 scopus 로고
    • Atherogenesis during low level hypercholesterolemia in the non human primate. II. Fatty streak conversion to fibrous plaque
    • Masuda, J., and R. Ross. 1990. Atherogenesis during low level hypercholesterolemia in the non human primate. II. Fatty streak conversion to fibrous plaque. Arteriosclerosis. 10:178-187.
    • (1990) Arteriosclerosis , vol.10 , pp. 178-187
    • Masuda, J.1    Ross, R.2
  • 43
    • 0025800329 scopus 로고
    • Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells
    • Amento, E.P., N Ehsani, H Palmer, and P. Libby 1991. Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells. Arterioscler Thromb. 11.1223-1230.
    • (1991) Arterioscler Thromb. , vol.11 , pp. 1223-1230
    • Amento, E.P.1    Ehsani, N.2    Palmer, H.3    Libby, P.4
  • 45
    • 0026082959 scopus 로고
    • Involvement of the immune system in human atherogenesis: Current knowledge and unanswered questions
    • Libby, P., and G.K. Hansson. 1991. Involvement of the immune system in human atherogenesis: current knowledge and unanswered questions. Lab Invest. 64:5-15.
    • (1991) Lab Invest. , vol.64 , pp. 5-15
    • Libby, P.1    Hansson, G.K.2
  • 46
    • 0027233082 scopus 로고
    • Interferon-γ inhibits macrophage apolipoprotein E production by posttranslational mechanisms
    • Brand, K., N Mackman, and L.K. Curtiss. 1993. Interferon-γ inhibits macrophage apolipoprotein E production by posttranslational mechanisms. J. Clin. Invest. 91:2031-2039.
    • (1993) J. Clin. Invest. , vol.91 , pp. 2031-2039
    • Brand, K.1    Mackman, N.2    Curtiss, L.K.3
  • 47
    • 0028258246 scopus 로고
    • Combinatorial interactions between AP-1 and ets domain proteins contribute to the developmental regulation of the macrophage scavenger receptor gene
    • Wu, H., K. Moulton, A. Horvai, S. Parik, and C.K. Glass. 1994. Combinatorial interactions between AP-1 and ets domain proteins contribute to the developmental regulation of the macrophage scavenger receptor gene. Mol. Cell. Biol. 14:2129-2139.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 2129-2139
    • Wu, H.1    Moulton, K.2    Horvai, A.3    Parik, S.4    Glass, C.K.5
  • 48
    • 0027365599 scopus 로고
    • Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells
    • Marui, N., M.K. Offermann, R. Swerlick, C. Kunsch, C.A. Rosen, M. Ahmad, R.W. Alexander, and R.M. Medford. 1993. Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. J. Clin. Invest. 92:1866-1874.
    • (1993) J. Clin. Invest. , vol.92 , pp. 1866-1874
    • Marui, N.1    Offermann, M.K.2    Swerlick, R.3    Kunsch, C.4    Rosen, C.A.5    Ahmad, M.6    Alexander, R.W.7    Medford, R.M.8
  • 49
    • 0028148369 scopus 로고
    • Antioxidants inhibit monocyte adhesion by suppressing nuclear factor-κB mobilization and induction of vascular adhesion molecule-1 in endothelial cells stimulated to generate radicals
    • Weber, C., W. Erl, A. Pietsch, M. Strobel, H.W.L. Ziegler-Heitbrock, and P C Weber. 1994. Antioxidants inhibit monocyte adhesion by suppressing nuclear factor-κB mobilization and induction of vascular adhesion molecule-1 in endothelial cells stimulated to generate radicals. Arterioscler Thromb 14 1665-1673.
    • (1994) Arterioscler Thromb , vol.14 , pp. 1665-1673
    • Weber, C.1    Erl, W.2    Pietsch, A.3    Strobel, M.4    Ziegler-Heitbrock, H.W.L.5    Weber, P.C.6
  • 50
    • 0026514362 scopus 로고
    • A dilemma for the 1990s choosing appropriate experimental animal model for the prevention of restenosis
    • Ferrell, M., V. Fuster, H.K. Gold, and J H Chesebro 1992. A dilemma for the 1990s choosing appropriate experimental animal model for the prevention of restenosis. Circulation. 85 1630-1631.
    • (1992) Circulation , vol.85 , pp. 1630-1631
    • Ferrell, M.1    Fuster, V.2    Gold, H.K.3    Chesebro, J.H.4
  • 51
    • 0024408772 scopus 로고
    • Cell constitution and characteristics of human atherosclerotic plaques selectively removed by percutaneus atherectomy
    • Dartsch, P.C., G. Bauriedel, I. Schinko, H.-D. Weiss, B. Höfling, and E. Betz. 1989. Cell constitution and characteristics of human atherosclerotic plaques selectively removed by percutaneus atherectomy. Atherosclerosis. 80: 149-157.
    • (1989) Atherosclerosis , vol.80 , pp. 149-157
    • Dartsch, P.C.1    Bauriedel, G.2    Schinko, I.3    Weiss, H.-D.4    Höfling, B.5    Betz, E.6


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