Attenuation of atherosclerosis in apolipoprotein E-deficient mice by ramipril is dissociated from its antihypertensive effect and from potentiation of bradykinin

Journal of Cardiovascular Pharmacology

Volumn 35, Issue 1, 2000, Pages 64-72

  Keidar, Shlomo ^a,c   Attias, Judith ^a   Coleman, Raymond ^a   Wirth, Klaus ^b   Schölkens, Bernward ^b   Hayek, Tony ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b SANOFI   (France)

^c RAMBAM MEDICAL CENTER   (Israel)

Author keywords

Atherosclerosis; Bradykinin; E0 mice; Ramipril

Indexed keywords

ANGIOTENSIN; APOLIPOPROTEIN E; BRADYKININ; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ICATIBANT; LOW DENSITY LIPOPROTEIN; PLACEBO; RAMIPRIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG MIXTURE; DRUG POTENTIATION; HYPERLIPOPROTEINEMIA TYPE 3; LIPID PEROXIDATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; ANTIHYPERTENSIVE AGENTS; AORTA, THORACIC; APOLIPOPROTEINS E; ARTERIOSCLEROSIS; BLOOD PRESSURE; BRADYKININ; CHOLESTEROL; DISEASE PROGRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; LIPOPROTEINS, LDL; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MYOCARDIUM; OXIDATION-REDUCTION; RAMIPRIL;

EID: 0033986442     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200001000-00008     Document Type: Article

References (1)

1. Chobanian A, Handenschild C, Nickerson C, Drago R. Antiatherogenic effect of captopril in the Watanabe heritable hyperlipidemic rabbit. Hypertension 1990;15:327-31.