Protein geranylgeranylation, not farnesylation, is required for the G1 to S phase transition in mouse fibroblasts

Oncogene

Volumn 13, Issue 9, 1996, Pages 1991-1999

  Vogt, Andreas ^a   Qian, Yimin ^b   McGuire, Terence F ^a   Hamilton, Andrew D ^b   Sebti, Saïd M ^a,c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

Cell cycle; Farnesyltransferase; Geranylgeranyltransferase; Prenylation; Ras

Indexed keywords

DNA; ENZYME INHIBITOR; FARNESOL; FARNESYL TRANS TRANSFERASE; GERANYLTRANSFERASE; GUANINE NUCLEOTIDE BINDING PROTEIN; MEVALONIC ACID; MEVINOLIN; TRITIUM;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL STRAIN 3T3; CONTROLLED STUDY; DNA SYNTHESIS; FLOW CYTOMETRY; MITOSIS INHIBITION; MOUSE; NONHUMAN; PRENYLATION; PRIORITY JOURNAL; PROTEIN MODIFICATION;

ACTINS; ALKYL AND ARYL TRANSFERASES; ANIMALS; BENZAMIDES; CELL CYCLE; CELL DIVISION; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CYTOSKELETON; DITERPENES; DNA; ENZYME INHIBITORS; FARNESOL; FIBROBLASTS; G0 PHASE; G1 PHASE; GENES, RAS; GTP-BINDING PROTEINS; LOVASTATIN; METHIONINE; MEVALONIC ACID; MICE; PROTEIN ISOPRENYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-RAF; RAP GTP-BINDING PROTEINS; RAS PROTEINS; S PHASE; TRANSFERASES;

ANIMALIA; TRITIUM;

EID: 0029857638     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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