RhoA prenylation inhibitor produces relaxation of tonic smooth muscle of internal anal sphincter

Journal of Pharmacology and Experimental Therapeutics

Volumn 321, Issue 2, 2007, Pages 501-508

  Patel, Chirag A ^a   Rattan, Satish ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; GGTI 297; N 4 [2 AMINO 3 MERCAPTOPROPYL]AMINO 2 NAPHTHYLBENZOYL LEUCINE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SPASMOLYTIC AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANUS SPHINCTER; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE RELAXATION;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ANAL CANAL; ANIMALS; BENZAMIDES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MUSCLE RELAXATION; MUSCLE, SMOOTH; PROTEIN ISOPRENYLATION; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; RHOA GTP-BINDING PROTEIN;

EID: 34247382147     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.107.119339     Document Type: Article

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