Recombinant protein scaffolds for tissue engineering

Biomedical Materials

Volumn 7, Issue 1, 2012, Pages

  Werkmeister, Jerome A ^a   Ramshaw, John A M ^a  

^a CSIRO   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MATERIALS; COST EFFECTIVENESS; COST ENGINEERING; GENETIC ENGINEERING; MOLECULAR BIOLOGY; PRODUCT DESIGN; PROTEINS; RECOMBINANT PROTEINS; TISSUE; TISSUE ENGINEERING; TISSUE REGENERATION;

BIOLOGICAL COMPLEXITY; BIOLOGICAL INFORMATION; EMERGING TECHNOLOGIES; GENETIC MANIPULATIONS; MECHANICAL INTEGRITY; SCAFFOLD FABRICATION; SYNTHETIC POLYMER SCAFFOLDS; TISSUE ENGINEERING SCAFFOLD;

SCAFFOLDS (BIOLOGY);

ALCOHOL OXIDASE; BIOMATERIAL; CHIMERIC PROTEIN; COLLAGEN; COLLAGEN TYPE 15; COLLAGEN TYPE 17; COLLAGEN TYPE 3; COLLAGEN TYPE 4; COLLAGEN TYPE 5; ELASTIN; GLYCINE; METHANOL; POLYMER; POLYURETHAN; RECOMBINANT PROTEIN; SCAFFOLD PROTEIN; SCLEROPROTEIN; TROPOELASTIN;

BACILLUS ANTHRACIS; BIODEGRADABILITY; BIODEGRADATION; CARBOXY TERMINAL SEQUENCE; CARTILAGE CELL; CELL LINE; CELL PROLIFERATION; CELL STRAIN HEK293; ESCHERICHIA COLI; EUKARYOTIC CELL; GENE SEQUENCE; HUMAN; IMMUNOGENICITY; IN VITRO STUDY; IN VIVO STUDY; MEDICAL TECHNOLOGY; MICROTECHNOLOGY; NANOFABRICATION; PICHIA PASTORIS; PROKARYOTIC CELL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN ISOLATION; REVIEW; SACCHAROMYCES; SILK; SMOOTH MUSCLE FIBER; TISSUE ENGINEERING; TRANSGENIC ANIMAL; TRANSGENIC PLANT;

EID: 84856418111     PISSN: 17486041     EISSN: 1748605X     Source Type: Journal    
DOI: 10.1088/1748-6041/7/1/012002     Document Type: Review

References (261)

1. Adachi T, Wang X, Murata T, Obara M, Akutsu H, Machida M, Umezawa A and Tomita M 2010 Production of a non-triple helical collagen alpha chain in transgenic silkworms and its evaluation as a gelatin substitute for cell culture Biotechnol. Bioeng. 106 860-70
2. Adams M D et al 2000 The genome sequence of Drosophila melanogaster Science 287 2185-95 (Pubitemid 30177013)
3. An B, Hinman M B, Holland G P, Yarger J L and Lewis R V 2011 Inducing β-sheets formation in synthetic spider silk fibers by aqueous post-spin stretching Biomacromolecules 12 2375-81
4. Andersen S O 1964 The cross-links in resilin identified as dityrosine and trityrosine Biochim. Biophys. Acta 93 213-5
5. Andersen S O 1971 Resilin Comprehensive Biochemistry vol 26C ed M Florkin and E H Stotz (Amsterdam: Elsevier) pp 633-57
6. Antonicelli F, Bellon G, Debelle L and Hornebeck W 2007 Elastin-elastases and inflammation-aging Curr. Top. Dev. Biol. 79 99-155
7. Arcidiacono S, Mello C, Kaplan D, Cheley S and Bayley H 1998 Purification and characterization of recombinant spider silk expressed in Escherichia coli Appl. Microbiol. Biotechnol. 49 31-8 (Pubitemid 28055378)
8. Ardell D H and Andersen S O 2001 Tentative identification of a resilin gene in Drosophila melanogaster Insect Biochem. Mol. Biol. 31 965-70 (Pubitemid 32785897)
9. Askarieh G, Hedhammar M, Nordling K, Saenz A, Casals C, Rising A, Johansson J and Knight S D 2010 Self-assembly of spider silk proteins is controlled by a pH-sensitive relay Nature 465 236-8
10. Atkins E D T 1967 A four-strand coiled-coil model for some insect fibrous proteins J. Mol. Biol. 24 139-41
11. Ayoub N A, Garb J E, Tinghitella R M, Collin M A and Hayashi C Y 2007 Blueprint for a high-performance biomaterial: full-length spider dragline silk genes PLoS One 13 e514
12. Báez J, Olsen D and Polarek J W 2005 Recombinant microbial systems for the production of human collagen and gelatine Appl. Microbiol. Biotechnol. 69 245-52 (Pubitemid 43014441)
13. Bandiera A, Sist P and Urbani R 2010 Comparison of thermal behavior of two recombinantly expressed human elastin-like polypeptides for cell culture applications Biomacromolecules 11 3256-65
14. Baoyong L, Jian Z, Denglong C and Min L 2010 Evaluation of a new type of wound dressing made from recombinant spider silk protein using rat models Burns 36 891-6
15. Barber E J W 1992 Prehistoric textiles: the development of cloth in the Neolithic and Bronze Ages with special reference to the Aegean (reprint, illustrated ed.) (Princeton, NJ: Princeton University Press) p 31
16. Bax D V, Rodgers U R, Bilek M M M and Weiss A S 2009 Cell adhesion to tropoelastin is mediated via the C-terminal GRKRK motif and integrin alpha(V)beta(3) J. Biol. Chem. 284 28616-23
17. Bedell-Hogan D, Trackman P, Abrams W, Rosenbloom J and Kagan H 1993 Oxidation, cross-linking, and insolubilization of recombinant tropoelastin by purified lysyl oxidase J. Biol. Chem. 268 10345-50 (Pubitemid 23150217)
18. Belin V and Rousselle P 2006 Production of a recombinantly expressed laminin fragment by HEK293-EBNA cells cultured in suspension in a dialysis-based bioreactor Protein Expr. Purif. 48 43-8 (Pubitemid 43796218)
19. Bellingham C M, Lillie M A, Gosline J M, Wright G M, Starcher B C, Bailey A J, Woodhouse K A and Keeley F W 2003 Recombinant human elastin polypeptides self-assemble into biomaterials with elastin-like properties Biopolymers 70 445-55 (Pubitemid 37531828)
20. Bellingham C M, Woodhouse K A, Robson P, Rothstein S J and Keeley F W 2001 Self-aggregation characteristics of recombinantly expressed human elastin polypeptides Biochim. Biophys. Acta 1550 6-19 (Pubitemid 33153060)
21. Berg R A 2000 Production of human recombinant collagen in the milk of transgenic animals US Patent 6111165
22. Betre H, Setton L A, Meyer D E and Chilkoti A 2002 Characterization of a genetically engineered elastin-like polypeptide for cartilaginous tissue repair Biomacromolecules 3 910-6
23. Bini E, Foo C W, Huang J, Karageorgiou V, Kitchel B and Kaplan D L 2006 RGD-functionalized bioengineered spider dragline silk biomaterial Biomacromolecules 7 3139-45 (Pubitemid 46039972)
24. Bonekamp F, Andersen H D, Christensen T and Jensen K F 1985 Codon-defined ribosomal pausing in Escherichia coli detected by using the pyrE attenuator to probe the coupling between transcription and translation Nucleic Acids Res. 13 4113-23
25. Boudko S P, Sasaki T, Engel J, Lerch T F, Nix J, Chapman M S and Bächinger H P 2009 Crystal structure of human collagen XVIII trimerization domain: a novel collagen trimerization fold J. Mol. Biol. 392 787-802
26. Bracalello A, Santopietro V, Vassalli M, Marletta G, Del Gaudio R, Bochicchio B and Pepe A 2011 Design and production of a chimeric resilin-, elastin-, and collagen-like engineered polypeptide Biomacromolecules 12 2957-65
27. Brahmbhatt T N, Darnell S C, Carvalho H M, Sanz P, Kang T J, Bull R L, Rasmussen S B, Cross A S and O'Brien A D 2007 Recombinant exosporium protein BclA of Bacillus anthracis is effective as a booster for mice primed with suboptimal amounts of protective antigen Infect. Immun. 75 5240-7 (Pubitemid 350033610)
28. Breasted J H 1930 The Edwin Smith Surgical Papyrus Chicago (Chicago, IL: University of Chicago Press)
29. Broekelmann T J, Kozel B A, Ishibashi H, Werneck C C, Keeley F W, Zhang L and Mecham R P 2005 Tropoelastin interacts with cell-surface glycosaminoglycans via its COOH-terminal domain J. Biol. Chem. 280 40939-47 (Pubitemid 41780588)
30. Burrows M 2003 Biomechanics: froghopper insects leap to new heights Nature 424 509 (Pubitemid 36975765)
31. Burrows M 2011 Jumping mechanisms and performance of snow fleas (Mecoptera, Boreidae) J. Exp. Biol. 214 2362-74
32. Cappello J 1998 High molecular weight collagen-like protein polymers US Patent 5773249
33. Caswell C C, Barczyk M, Keene D R, Lukomska E, Gullberg D E and Lukomski S 2008 Identification of the first prokaryotic collagen sequence motif that mediates binding to human collagen receptors, integrins alpha2beta1 and alpha11beta1 J. Biol. Chem. 283 36168-75
34. Caswell C C, Oliver-Kozup H, Han R, Lukomska E and Lukomski S 2010 Scl1, the multifunctional adhesin of group A Streptococcus, selectively binds cellular fibronectin and laminin, and mediates pathogen internalization by human cells FEMS Microbiol. Lett. 303 61-8
35. Charati M B, Ifkovits J L, Burdick J A, Linhardt J G and Kiick K L 2009 Hydrophilic elastomeric biomaterials based on resilin-like polypeptides Soft Matter 5 3412-16
36. Clarke A W, Arnspang E C, Mithieux S M, Korkmaz E, Braet F and Weiss A S 2006 Tropoelastin massively associates during coacervation to form quantized protein spheres Biochemistry 45 9989-96 (Pubitemid 44257393)
37. Cosgriff-Hernandez E, Hahn M S, Russell B, Wilems T, Munoz-Pinto D, Browning M B, Rivera J and Höök M 2010 Bioactive hydrogels based on Designer Collagens Acta Biomater. 6 3969-77
38. Dal Pra I, Freddi G, Minic J, Chiarini A and Armato U 2005 De novo engineering of reticular connective tissue in vivo by silk fibroin nonwoven materials Biomaterials 26 1987-99 (Pubitemid 39575341)
39. Dame M K and Varani J 2008 Recombinant collagen for animal product-free dextran microcarriers In Vitro Cell Dev. Biol. Anim. 44 407-14
40. Davis E C 1993 Stability of elastin in the developing mouse aorta: a quantitative radioautographic study Histochemistry 100 17-26 (Pubitemid 23240229)
41. Davison I G, Wright G M and DeMont M E 1995 The structure and physical properties of invertebrate and primitive vertebrate arteries J. Exp. Biol. 198 2185-96
42. Debelle L and Tamburro A M 1999 Elastin: molecular description and function Int. J. Biochem. Cell Biol. 31 261-72 (Pubitemid 29094776)
43. de Bruin E C, Werten M W, Laane C and de Wolf F A 2002 Endogenous prolyl 4-hydroxylation in Hansenula polymorpha and its use for the production of hydroxylated recombinant gelatin FEMS Yeast Res. 1 291-8
44. Dravida S, Gaddipati S, Griffith M, Merrett K, Lakshmi Madhira S, Sangwan V S and Vemuganti G K 2008 A biomimetic scaffold for culturing limbal stem cells: a promising alternative for clinical transplantation J. Tissue Eng. Regen. Med. 2 263-71
45. Du C, Wang M, Liu J, Pan M, Cai Y and Yao J 2008 Improvement of thermostability of recombinant collagen-like protein by incorporating a foldon sequence Appl. Microbiol. Biotechnol. 79 195-202 (Pubitemid 351581077)
46. Dyck M K, Lacroix D, Pothier F and Sirard M A 2003 Making recombinant proteins in animals - different systems, different applications Trends Biotechnol. 21 394-9 (Pubitemid 37028312)
47. Elvin C M, Carr A G, Huson M G, Maxwell J M, Pearson R D, Vuocolo T, Liyou N E, Wong D C, Merritt D J and Dixon N E 2005 Synthesis and properties of crosslinked recombinant pro-resilin Nature 437 999-1002
48. Engler A J, Sen S, Sweeney H L and Discher D E 2006 Matrix elasticity directs stem cell lineage specification Cell 126 677-89 (Pubitemid 44233625)
49. Eskelin K, Ritala A, Suntio T, Blumer S, Holkeri H, Wahlström E H, Baez J, Mäkinen K and Maria N A 2009 Production of a recombinant full-length collagen type I alpha-1 and of a 45-kDa collagen type I alpha-1 fragment in barley seeds Plant Biotechnol. J. 7 657-72
50. Fahnestock S R and Bedzyk L A 1997 Production of synthetic spider dragline silk protein in Pichia pastoris Appl. Microbiol. Biotechnol. 47 33-9 (Pubitemid 27077296)
51. Fancy D A and Kodadek T 1999 Chemistry for the analysis of protein-protein interactions: rapid and efficient cross-linking triggered by long wavelength light Proc. Natl Acad. Sci. USA 96 6020-4 (Pubitemid 29256612)
52. Ferrari F A, Richardson C, Chambers J, Causey S C, Pollock T J, Capello J and Crissman J W 1993 DNA composition encoding peptide containing oligopeptide repeating unit(s) US Patent 5243038
53. Ferretti J J et al 2001 Complete genome sequence of an M1 strain of Streptococcus pyogenes Proc. Natl Acad. Sci. USA 98 4658-63 (Pubitemid 32295032)
54. Fredriksson C et al 2009 Tissue response to subcutaneously implanted recombinant spider silk: an in vivo study Materials 2 1908-22
55. Gage L P and Manning R F 1980 Internal structure of the silk fibroin gene of Bombyx mori: I. The fibroin gene consists of a homogeneous alternating array of repetitious crystalline and amorphous coding sequences J. Biol. Chem. 255 9444-50
56. Gatesy J, Hayashi C, Motriuk J, Woods J and Lewis R 2001 Extreme diversity, conservation, and convergence of spider silk fibroin sequences Science 291 2603-5 (Pubitemid 32249684)
57. Geerlings T H, de Boer A L, Lunenborg M G, Veenhuis M and van der Klei I J 2007 A novel platform for the production of nonhydroxylated gelatins based on the methylotrophic yeast Hansenula polymorpha FEMS Yeast Res. 7 1188-96
58. Gerritsen V B 2002 The tiptoe of an airbus Proteinspotlight Issue 24 http://web.expasy.org/spotlight/back-issues/024/
59. Girotti A, Reguera J, Rodríguez-Cabello J C, Arias F J, Alonso M and Matestera A 2004 Design and bioproduction of a recombinant multi(bio)functional elastin-like protein polymer containing cell adhesion sequences for tissue engineering purposes J. Mater. Sci. Mater. Med. 15 479-84 (Pubitemid 39012166)
60. Gosline J M, Denny M W and Demont M E 1984 Spider silk as rubber Nature 309 551-2
61. Gosline J M, Guerette P A, Ortlepp C S and Savage K N 1999 The mechanical design of spider silks: from fibroin sequence to mechanical function J. Exp. Biol. 202 3295-303 (Pubitemid 30018435)
62. Gosline J, Lillie M, Carrington E, Guerette P, Ortlepp C and Savage K 2002 Elastic proteins: biological roles and mechanical properties Phil. Trans. R. Soc. B 357 121-32 (Pubitemid 34276203)
63. Grosso L E, Parks W C, Wu L J and Mecham R P 1991 Fibroblast adhesion to recombinant tropoelastin expressed as a protein A-fusion protein Biochem. J. 273 517-22
64. Grosso L E and Scott M 1993 PGAIPG, a repeated hexapeptide of bovine tropoelastin, is a ligand for the 67-kDa bovine elastin receptor Matrix 13 157-64 (Pubitemid 23091351)
65. Guda C, Lee S-B and Daniell H 2000 Stable expression of a biodegradable protein-based polymer in tobacco chloroplasts Plant Cell Rep. 19 257-62 (Pubitemid 30067908)
66. Guo J, Luo Y, Fan D, Yang B, Gao P, Ma X and Zhu C 2010 Medium optimization based on the metabolic-flux spectrum of recombinant Escherichia coli for high expression of human-like collagen II Biotechnol. Appl. Biochem. 57 55-62
67. Gustafson J A and Ghandehari H 2010 Silk-elastin-like protein polymers for matrix-mediated cancer gene therapy Adv. Drug Deliv. Rev. 62 1509-23
68. Haas F, Gorb S and Blickhan R 2000 The function of resilin in beetle wings Proc. Biol. Sci. 267 1375-81 (Pubitemid 30612365)
69. Haider M, Cappello J, Ghandehari H and Leong K W 2008 In vitro chondrogenesis of mesenchymal stem cells in recombinant silk-elastinlike hydrogels Pharm. Res. 25 692-9 (Pubitemid 351357715)
70. Han S, Makareeva E, Kuznetsova N V, DeRidder A M, Sutter M B, Losert W, Phillips C L, Visse R, Nagase H and Leikin S 2010 Molecular mechanism of type I collagen homotrimer resistance to mammalian collagenases J. Biol. Chem. 285 22276-81
71. Hashizume F, Hino S, Kakehashi M, Okajima T, Nadano D, Aoki N and Matsuda T 2008 Development and evaluation of transgenic rice seeds accumulating a type II-collagen tolerogenic peptide Transgenic Res. 17 1117-29
72. Hayashi C Y and Lewis R V 2000 Molecular architecture and evolution of a modular spider silk protein gene Science 287 1477-9 (Pubitemid 30127139)
73. Hedhammar M, Bramfeldt H, Baris T, Widhe M, Askarieh G, Nordling K, Aulock S and Johansson J 2010 Sterilized recombinant spider silk fibers of low pyrogenicity Biomacromolecules 11 953-9
74. Heilshorn S C, Liu J C and Tirrell D A 2005 Cell-binding domain context affects cell behavior on engineered proteins Biomacromolecules 6 318-23 (Pubitemid 40277029)
75. Heim M, Römer L and Scheibel T 2010 Hierarchical structures made of proteins. The complex architecture of spider webs and their constituent silk proteins Chem. Soc. Rev. 39 156-64
76. Hepburn H R, Chandler H D and Davidoff M R 1979 Extensiometric properties of insect fibroins: the green lacewing cross-β, honeybee α-helical and greater waxmoth parallel-βconformations Insect Biochem. 9 69-77
77. Hepburn H R and Kurstjens S P 1988 The combs of honeybees as composite-materials Apidologie 19 25-36
78. Hinek A 1994 Nature and the multiple functions of the 67-kd elastin/laminin binding-protein Cell Adhes. Commun. 2 185-93 (Pubitemid 24282665)
79. Hinman M B and Lewis R V 1992 Isolation of a clone encoding a second dragline silk fibroin. Nephila clavipes dragline silk is a two-protein fiber J. Biol. Chem. 267 19320-4
80. Hino R, Tomita M and Yoshizato K 2006 The generation of germline transgenic silkworms for the production of biologically active recombinant fusion proteins of fibroin and human basic fibroblast growth factor Biomaterials 27 5715-24 (Pubitemid 44279069)
81. Houdebine L M 2009 Production of pharmaceutical proteins by transgenic animals Comp. Immunol. Microbiol. Infect. Dis. 32 107-21
82. Hrabchak C, Rouleau J, Moss I, Woodhouse K, Akens M, Bellingham C, Keeley F, Dennis M and Yee A 2010 Assessment of biocompatibility and initial evaluation of genipin cross-linked elastin-like polypeptides in the treatment of an osteochondral knee defect in rabbits Acta Biomater. 6 2108-15
83. Hu K, Cui F, Lv Q, Ma J, Feng Q, Xu L and Fan D 2008 Preparation of fibroin/recombinant human-like collagen scaffold to promote fibroblasts compatibility J. Biomed. Mater. Res. A 84 483-90
84. Huang J, Wong C, George A and Kaplan D L 2007 The effect of genetically engineered spider silk-dentin matrix protein 1 chimeric protein on hydroxyapatite nucleation Biomaterials 28 2358-67 (Pubitemid 46282927)
85. Humtsoe J O, Kim J K, Xu Y, Keene D R, Höök M, Lukomski S and Wary K K 2005 A streptococcal collagen-like protein interacts with the alpha2beta1 integrin and induces intracellular signaling J. Biol. Chem. 280 13848-57 (Pubitemid 40517283)
86. Hurskainen M, Ruggiero F, Hägg P, Pihlajaniemi T and Huhtala P 2010 Recombinant human collagen XV regulates cell adhesion and migration J. Biol. Chem. 285 5258-65
87. Indik Z, Abrams W R, Kucich U, Gibson C W, Mecham R P and Rosenbloom J 1990 Production of recombinant human tropoelastin: characterization and demonstration of immunologic and chemotactic activity Arch. Biochem. Biophys. 280 80-6 (Pubitemid 20196537)
88. Ito H, Steplewski A, Alabyeva T and Fertala A 2006 Testing the utility of rationally engineered recombinant collagen-like proteins for applications in tissue engineering J. Biomed. Mater. Res. A 76 551-60
89. Jensen S A, Reinhardt D P, Gibson M A and Weiss A S 2001 Protein interaction studies of MAGP-1 with tropoelastin and fibrillin-1 J. Biol. Chem. 276 39661-66
90. Jensen S A, Vrhovski B and Weiss A S 2000 Domain 26 of tropoelastin plays a dominant role in association by coacervation J. Biol. Chem. 275 28449-54
91. Jin H J, Fridrikh S V, Rutledge G C and Kaplan D L 2002 Electrospinning Bombyx mori silk with poly(ethylene oxide) Biomacromolecules 3 1233-9 (Pubitemid 35428773)
92. John D C, Watson R, Kind A J, Scott A R, Kadler K E and Bulleid N J 1999 Expression of an engineered form of recombinant procollagen in mouse milk Nat. Biotechnol. 17 385-9 (Pubitemid 29166043)
93. Jordan S W, Haller C A, Sallach R E, Apkarian R P, Hanson S R and Chaikof E L 2007 The effect of a recombinant elastin-mimetic coating of an ePTFE prosthesis on acute thrombogenicity in a baboon arteriovenous shunt Biomaterials 28 1191-7 (Pubitemid 44809410)
94. Kajitani M, Wadia Y, Hinds M T, Teach J, Swartz K R and Gregory K W 2001 Successful repair of esophageal injury using an elastin based biomaterial patch ASAIO J. 47 342-5 (Pubitemid 32655804)
95. Kajitani M, Wadia Y, Xie H, Hinds M T, Shalaby S W, Swartz K R and Gregory K W 2000 Use of a new elastin patch and glue for repair of a major duodenal injury ASAIO J. 46 409-14 (Pubitemid 30459184)
96. Kato T, Kajikawa M, Maenaka K and Park E Y 2010 Silkworm expression system as a platform technology in life science Appl. Microbiol. Biotechnol. 85 459-70
97. Kaufmann D, Fiedler A, Junger A, Auernheimer J, Kessler H and Weberskirch R 2008 Chemical conjugation of linear and cyclic RGD moieties to a recombinant elastin-mimetic polypeptide-a versatile approach towards bioactive protein hydrogels Macromol. Biosci. 8 577-88
98. Keeley F W, Bellingham C M and Woodhouse K A 2002 Elastin as a self-organizing biomaterial: use of recombinantly expressed human elastin polypeptides as a model for investigations of structure and self-assembly of elastin Phil. Trans. R. Soc. B 357 185-9 (Pubitemid 34276209)
99. Kim M, Elvin C, Brownlee A and Lyons R 2007 High yield expression of recombinant pro-resilin: lactose-induced fermentation in E. coli and facile purification Protein Expr. Purif. 52 230-6 (Pubitemid 46038763)
100. Kim U J, Park J, Kim H J, Wada M and Kaplan D L 2005 Three-dimensional aqueous-derived biomaterial scaffolds from silk fibroin Biomaterials 26 2775-85 (Pubitemid 39600730)
101. Kim U J, Park J, Li C, Jin H J, Valluzzi R and Kaplan D L 2004 Structure and properties of silk hydrogels Biomacromolecules 5 786-92 (Pubitemid 38702247)
102. Kinahan M E, Filippidi E, Köster S, Hu X, Evans H M, Pfohl T, Kaplan D L and Wong J 2011 Tunable silk: using microfluidics to fabricate silk fibers with controllable properties Biomacromolecules 12 1504-11
103. Kinikoglu B, Rodríguez-Cabello J C, Damour O and Hasirci V 2011 A smart bilayer scaffold of elastin-like recombinamer and collagen for soft tissue engineering J. Mater. Sci. Mater. Med. 22 1541-54
104. Koch M, Schulze J, Hansen U, Ashwodt T, Keene D R, Brunken W J, Burgeson R E, Bruckner P and Bruckner-Tuderman L 2004 A novel marker of tissue junctions, collagen XXII J. Biol. Chem. 279 22514-21 (Pubitemid 38679451)
105. Krishna O D and Kiick K 2009 Supramolecular assembly of electrostatically stabilized, hydroxyproline-lacking collagen-mimetic peptides Biomacromolecules 10 2626-31
106. Kyle S, Aggeli A, Ingham E and McPherson M J 2009 Production of self-assembling biomaterials for tissue engineering Trends Biotechnol. 27 423-33
107. Lagali N, Griffith M, Fagerholm P, Merrett K, Huynh M and Munger R 2008 Innervation of tissue-engineered recombinant human collagen-based corneal substitutes: a comparative in vivo confocal microscopy study Invest. Ophthalmol. Vis. Sci. 49 3895-902
108. Landreh M et al 2010 A pH-dependent dimer lock in spider silk protein J. Mol. Biol. 404 328-36
109. Lazaris A, Arcidiacono S, Huang Y, Zhou J F, Duguay F, Chretien N, Welsh E A, Soares J W and Karatzas C N 2002 Spider silk fibers spun from soluble recombinant silk produced in mammalian cells Science 295 472-6 (Pubitemid 34101631)
110. Li L, Teller S, Clifton R J, Jia X and Kiick K L 2011 Tunable mechanical stability and deformation response of a resilin-based elastomer Biomacromolecules 12 2302-10
111. Liu W et al 2008 Recombinant human collagen for tissue engineered corneal substitutes Biomaterials 29 1147-58
112. Liu W et al 2009 Collagen-phosphorylcholine interpenetrating network hydrogels as corneal substitutes Biomaterials 30 1551-9
113. Lombardi S J and Kaplan D L 1990 The amino-acid-composition of major ampullate gland silk (dragline) of Nephila clavipes (araneae, tetragnathidae) J. Arachnol. 18 297-306
114. Lukomski S, Nakashima K, Abdi I, Cipriano V J, Ireland R M, Reid S D, Adams G G and Musser J M 2000 Identification and characterization of the scl gene encoding a group A Streptococcus extracellular protein virulence factor with similarity to human collagen Infect. Immun. 68 6542-53 (Pubitemid 32463352)
115. Lukomski S, Nakashima K, Abdi I, Cipriano V J, Shelvin B J, Graviss E A and Musser J M 2001 Identification and characterization of a second extracellular collagen-like protein made by group A Streptococcus: control of production at the level of translation Infect. Immun. 69 1729-38 (Pubitemid 32187632)
116. Lyons R E, Lesieur E, Kim M, Wong D C, Huson M G, Nairn K M, Brownlee A G, Pearson R D and Elvin C M 2007 Design and facile production of recombinant resilin-like polypeptides: gene construction and a rapid protein purification method Protein Eng. Des. Sel. 20 25-32
117. Lyons R E, Nairn K M, Huson M G, Kim M, Dumsday G and Elvin C M 2009 Comparisons of recombinant resilin-like proteins: repetitive domains are sufficient to confer resilin-like properties Biomacromolecules 10 3009-14
118. Ma X, Fan D, Shang L A, Cai Q, Chi L, Zhu C, Mi Y and Luo Y E 2010 Oxygen transfer rate control in the production of human-like collagen by recombinant Escherichia coli Biotechnol. Appl. Biochem. 55 169-74
119. MacEwan S R and Chilkoti A 2010 Elastin-like polypeptides: biomedical applications of tunable biopolymers Biopolymers 94 60-77
120. MacKenzie D 1973 The history of sutures Med. Hist. 17 158-68
121. Majsterek I, McAdams E, Adachi E, Dhume S T and Fertala A 2003 Prospects and limitations of the rational engineering of fibrillar collagens Protein Sci. 12 2063-72 (Pubitemid 37022827)
122. Mandal B B and Kundu S C 2009 Osteogenic and adipogenic differentiation of rat bone marrow cells on non-mulberry and mulberry silk gland fibroin 3D scaffolds Biomaterials 30 5019-30
123. Martín L, Alonso M, Girotti A, Arias F J and Rodríguez- Cabello J C 2009 Synthesis and characterization of macroporous thermosensitive hydrogels from recombinant elastin-like polymers Biomacromolecules 10 3015-22
124. Martin S L, Vrhovski B and Weiss A S 1995 Total synthesis and expression in Escherichia coli of a gene encoding human tropoelastin Gene 154 159-66
125. Martínez-Osorio H, Júarez-Campo M, Diebold Y, Girotti A, Alonso M, Arias F J, Rodríguez-Cabello J C, García-Vázquez C and Calonge M 2009 Genetically engineered elastin-like polymer as a substratum to culture cells from the ocular surface Curr. Eye Res. 34 48-56
126. Menassa R, Zhu H, Karatzas C N, Lazaris A, Richman A and Brandle J 2004 Spider dragline silk proteins in transgenic tobacco leaves: accumulation and field production Plant Biotechnol. J. 2 431-8 (Pubitemid 40199435)
127. Merrett K et al 2008 Tissue-engineered recombinant human collagen-based corneal substitutes for implantation: performance of type I versus type III collagen Invest. Ophthalmol. Vis. Sci. 49 3887-94
128. Merrett K, Liu W, Mitra D, Camm K D, McLaughlin C R, Liu Y, Watsky M A, Li F, Griffith M and Fogg D E 2009 Synthetic neoglycopolymer-recombinant human collagen hybrids as biomimetic crosslinking agents in corneal tissue engineering Biomaterials 30 5403-8
129. Meyer D E and Chilkoti A 2002 Genetically encoded synthesis of protein-based polymers with precisely specified molecular weight and sequence by recursive directional ligation: examples from the elastin-like polypeptide system Biomacromolecules 3 357-67 (Pubitemid 34257157)
130. Miao M, Bellingham C M, Stahl R J, Sitarz E E, Lane C J and Keeley F W 2003 Sequence and structure determinants for the self-aggregation of recombinant polypeptides modeled after human elastin J. Biol. Chem. 278 48553-62 (Pubitemid 41079493)
131. Mie M, Mizushima Y and Kobatake E 2008 Novel extracellular matrix for cell sheet recovery using genetically engineered elastin-like protein J. Biomed. Mater. Res. B; Appl. Biomater. 86 283-90 (Pubitemid 351874394)
132. Min B M, Lee G, Kim S H, Nam Y S, Lee T S and Park W H 2004 Electrospinning of silk fibroin nanofibers and its effect on the adhesion and spreading of normal human keratinocytes and fibroblasts in vitro Biomaterials 25 1289-97 (Pubitemid 37476206)
133. Minoura N, Tsukada M and Nagura M 1990 Physico-chemical properties of silk fibroin membrane as a biomaterial Biomaterials 11 430-4 (Pubitemid 20300839)
134. Mita K, Ichimura S and James T C 1994 Highly repetitive structure and its organization of the silk fibroin gene J. Mol. Evol. 38 583-92 (Pubitemid 24177291)
135. Mithieux S M, Rasko J E and Weiss A S 2004 Synthetic elastin hydrogels derived from massive elastic assemblies of self-organized human protein monomers Biomaterials 25 4921-7 (Pubitemid 38520822)
136. Mithieux S M, Tu Y, Korkmaz E, Braet F and Weiss A S 2009 In situ polymerization of tropoelastin in the absence of chemical cross-linking Biomaterials 30 431-5
137. Mohs A, Silva T, Yoshida T, Amin R, Lukomski S, Inouye M and Brodsky B 2007 Mechanism of stabilization of a bacterial collagen triple helix in the absence of hydroxyproline J. Biol. Chem. 282 29757-65 (Pubitemid 350035254)
138. Mori K, Tanaka K, Kikuchi Y,Waga M,Waga S and Mizuno S 1995 Production of a chimeric fibroin light-chain polypeptide in a fibroin secretion-deficient naked pupa mutant of the silkworm Bombyx mori J. Mol. Biol. 251 217-28
139. Nagaoka M, Jiang H-L, Hoshiba T, Akaike T and Cho C-S 2010 Application of recombinant fusion proteins for tissue engineering Ann. Biomed. Eng. 38 683-93
140. Nahirney P C, Forbes J G, Morris H D, Chock S C andWang K 2006 What the buzz was all about: superfast song muscles rattle the tymbals of male periodical cicadas FASEB J. 20 2017-26 (Pubitemid 44953902)
141. Nazarov R, Jin H J and Kaplan D L 2004 Porous 3-D scaffolds from regenerated silk fibroin Biomacromolecules 5 718-26 (Pubitemid 38702237)
142. Nettles D L, Chilkoti A and Setton L A 2010 Applications of elastin-like polypeptides in tissue engineering Adv. Drug Deliv. Rev. 62 1479-85
143. Neubauer A, Neubauer P and Myllyharju J 2005 High-level production of human collagen prolyl 4-hydroxylase in Escherichia coli Matrix Biol. 24 59-68 (Pubitemid 40320899)
144. Neubauer A, Soini J, Bollok M, Zenker M, Sandqvist J, Myllyharju J and Neubauer P 2007 Fermentation process for tetrameric human collagen prolyl 4-hydroxylase in Escherichia coli: improvement by gene optimisation of the PDI/beta subunit and repeated addition of the inducer anhydrotetracycline J. Biotechnol. 128 308-21 (Pubitemid 46074202)
145. Nivison-Smith L, Rnjak J and Weiss A S 2010 Synthetic human elastin microfibers: stable cross-linked tropoelastin and cell interactive constructs for tissue engineering applications Acta Biomater. 6 354-9
146. Nivison-Smith L and Weiss A S 2012 Alignment of human vascular smooth muscle cells on parallel electrospun synthetic elastin fibers J. Biomed. Mater. Res. A 100 155-61
147. Okada S, Weisman S, Trueman H E, Mudie S T, Haritos V S and Sutherland T D 2008 An Australian webspinner species makes the finest known insect silk fibers Int. J. Biol. Macromol. 43 271-5
148. Olsen D, Yang C, Bodo M, Chang R, Leigh S, Baez J, Carmichael D, Perälä M, Hämäläinen E R, Jarvinen M and Polarek J 2003 Recombinant collagen and gelatin for drug delivery Adv. Drug Deliv. Rev. 55 1547-67 (Pubitemid 37412593)
149. Omenetto F G and Kaplan D L 2010 New opportunities for an ancient material Science 329 528-31
150. Pakkanen O, Hämäläinen E R, Kivirikko K I and Myllyharju J 2003 Assembly of stable human type I and III collagen molecules from hydroxylated recombinant chains in the yeast Pichia pastoris. Effect of an engineered C-terminal oligomerization domain foldon J. Biol. Chem. 278 32478-83 (Pubitemid 37048447)
151. Paraman I, Fox S R, Aspelund M T, Glatz C E and Johnson L A 2010 Recovering corn germ enriched in recombinant protein by wet-fractionation Bioresour. Technol. 101 239-44
152. Parkhe A D, Seeley S K, Gardner K, Thompson L and Lewis R V 1997 Structural studies of spider silk proteins in the fiber J. Mol. Recognit. 10 1-6 (Pubitemid 27218741)
153. Peng Y Y, Glattauer V, Ramshaw J A M and Werkmeister J A 2010a Evaluation of the immunogenicity and cell compatibility of avian collagen for biomedical applications J. Biomed. Mater. Res. A 93 1235-44
154. Peng Y Y et al 2010b A Streptococcus pyogenes derived collagen-like protein as a non-cytotoxic and non-immunogenic cross-linkable biomaterial Biomaterials 31 2755-61
155. Peng Y Y, Werkmeister J A, Vaughan P R and Ramshaw J A 2009 Constructs for the expression of repeating triple-helical protein domains Biomed. Mater. 4 015006
156. Pepe A, Flamia R, Guerra D, Quaglino D, Bochicchio B, Pasquali Ronchetti I and Tamburro A M 2008 Exon 26-coded polypeptide: an isolated hydrophobic domain of human tropoelastin able to self-assemble in vitro Matrix Biol. 27 441-50
157. Perret S, Merle C, Bernocco S, Berland P, Garrone R, Hulmes D J, Theisen M and Ruggiero F 2001 Unhydroxylated triple helical collagen I produced in
158. Persikov A V, Ramshaw J A and Brodsky B 2005a Prediction of collagen stability from amino acid sequence J. Biol. Chem. 280 19343-9 (Pubitemid 41379641)
159. Persikov A V, Ramshaw J A, Kirkpatrick A and Brodsky B 2005b Electrostatic interactions involving lysine make major contributions to collagen triple-helix stability Biochemistry 44 1414-22 (Pubitemid 40204385)
160. Powell J T, Vine N and Crossman M 1992 On the accumulation of D-aspartate in elastin and other proteins of the aging aorta Atherosclerosis 97 201-8
161. Prockop D J, Ala-Kokko L, Fertala A, Kivirikko K I and Geddis A 1993 Synthesis of human procollagens and collagens in recombinant DNA systems Patent. International Publication Number WO 93/07889
162. Pulkkinen H J, Tiitu V, Valonen P, Hamalainen E R, Lammi M J and Kiviranta I 2008 Recombinant human type II collagen as a material for cartilage tissue engineering Int. J. Artif. Organs 31 960-9
163. Pulkkinen H J, Tiitu V, Valonen P, Jurvelin J S, Lammi M J and Kiviranta I 2010 Engineering of cartilage in recombinant human type II collagen gel in nude mouse model in vivo Osteoarthritis Cartilage 18 1077-87
164. Qin G, Lapidot S, Numata K, Hu X, Meirovitch S, Dekel M, Podoler I, Shoseyov O and Kaplan D L 2009 Expression, cross-linking, and characterization of recombinant chitin binding resilin Biomacromolecules 10 3227-34
165. Qiu W, Huang Y, Teng W, Cohn C M, Cappello J and Wu X 2010 Complete recombinant silk-elastinlike protein-based tissue scaffold Biomacromolecules 11 3219-27
166. Ramachandran G N 1988 Stereochemistry of collagen Int. J. Pept. Protein Res. 31 1-16
167. Rammensee S, Huemmerich D, Hermanson K D, Scheibel T and Bausch A R 2006 Rheological characterization of hydrogels formed by recombinantly produced spider silk Appl. Phys. A 82 261-4 (Pubitemid 41744323)
168. Ramshaw J A M, Peng Y, Glattauer V and Werkmeister J A 2009 Collagens as biomaterials J. Mater. Sci., Mater. Med. 20 S3-8
169. Rapaka R S, Okamoto K and Urry DW1978 Coaceration properties in sequential polypeptide models of elastin. Synthesis of H-(Ala-Pro-Gly-Gly)(n)- Val-OMe and H-(Ala-Pro-Gly-Val-Gly(n)-Val-OMe Int. J. Pept. Protein Res. 12 81-92 (Pubitemid 9000686)
170. Rasmussen M, Jacobsson M and Björck L 2003 Genome-based identification and analysis of collagen-related structural motifs in bacterial and viral proteins J. Biol. Chem. 278 32313-6 (Pubitemid 37048426)
171. Ricard-Blum S, Beraud M, Raynal N, Farndale R W and Ruggiero F 2006 Structural requirements for heparin/heparan sulfate binding to type V collagen J. Biol. Chem. 281 25195-204 (Pubitemid 44401906)
172. Rising A, Hjälm G, Engström W and Johansson J 2006 N-terminal nonrepetitive domain common to dragline, flagelliform, and cylindriform spider silk proteins Biomacromolecules 7 3120-4 (Pubitemid 46039969)
173. Ritala A, Wahlström E H, Holkeri H, Hafren A, Mäkeläinen K, Baez J, Mäkinen K and Nuutila A M 2008 Production of a recombinant industrial protein using barley cell cultures Protein Expr. Purif. 59 274-81
174. Rnjak J, Li Z, Maitz P K, Wise S G and Weiss A S 2009 Primary human dermal fibroblast interactions with open weave three-dimensional scaffolds prepared from synthetic human elastin Biomaterials 30 6469-77
175. Rock M J, Cain S A, Freeman L J, Morgan A, Mellody K, Marson A, Shuttleworth C A, Weiss A S and Kielty C M 2004 Molecular basis of elastic fiber formation. Critical interactions and a tropoelastin-fibrillin-1 cross-link J. Biol. Chem. 279 23748-58 (Pubitemid 38685691)
176. Rodgers U R and Weiss A S 2004 Integrin alpha v beta 3 binds a unique non-RGD site near the C-terminus of human tropoelastin Biochimie 86 173-8 (Pubitemid 38591505)
177. Römer L and Scheibel T 2008 The elaborate structure of spider silk: structure and function of a natural high performance fiber Landes Biosciences (Austin, TX: Landes Bioscience) pp 121-35
178. Roulet M, Välkkilä M, Chanut-Delalande H, Hämälä inen E R, Kessler E, Ala-Kokko L, Männikkö M, Bonod-Bidaud C and Ruggiero F 2010 The collagen V homotrimer [alpha1(V)](3) production is unexpectedly favored over the heterotrimer [alpha1(V)](2)alpha2(V) in recombinant expression systems J. Biomed. Biotechnol. 2010 376927
179. Rudall K M, Florkin M and Mason H S 1962 Silk and other cocoon proteins Comparative Biochemistry vol 4 (New York: Academic) pp 397-433
180. Ruggiero F, Exposito J Y, Bournat P, Gruber V, Perret S, Comte J, Olagnier B, Garrone R and Theisen M 2000 Triple helix assembly and processing of human collagen produced in transgenic tobacco plants FEBS Lett. 469 132-6 (Pubitemid 30119883)
181. Ruggiero F and Koch M 2008 Making recombinant extracellular matrix proteins - review Methods 45 75-85 (Pubitemid 351618377)
182. Ruottinen M, Bollok M, Kögler M, Neubauer A, Krause M, Hämäläinen E R, Myllyharju J, Vasala A and Neubauer P 2008 Improved production of human type II procollagen in the yeast Pichia pastoris in shake flasks by a wireless-controlled fed-batch system BMC Biotechnol. 8 33-44
183. Sallach R E, Conticello V P and Chaikof E L 2009a Expression of a recombinant elastin-like protein in Pichia pastoris Biotechnol. Prog. 25 1810-8
184. Sallach R E, Cui W, Balderrama F, Martinez A W, Wen J, Haller C A, Taylor J V, Wright E R, Long R C and Chaikof E L 2010 Long-term biostability of self-assembling protein polymers in the absence of covalent crosslinking Biomaterials 31 779-91
185. Sallach R E, Cui W, Wen J, Martinez A, Conticello V P and Chaikof E L 2009b Elastin-mimetic protein polymers capable of physical and chemical crosslinking Biomaterials 30 409-22
186. Sandberg L B and Wolt T B 1982 Production and isolation of soluble elastin from copper-deficient swine Methods Enzymol. 82 657-65
187. Schacht K and Scheibel T 2011 Controlled hydrogel formation of a recombinant spider silk protein Biomacromolecules 12 2488-95
188. Scheller J, Henggeler D, Viviani A and Conrad U 2004 Purification of spider silk-elastin from transgenic plants and application for human chondrocyte proliferation Transgenic Res. 13 51-7 (Pubitemid 38335389)
189. Senior R M, Griffin G L, Mecham R P, Wrenn D S, Prasad K U and Urry D W 1984 Val-Gly-Val-Ala-Pro-Gly, a repeating peptide in elastin, is chemotactic for fibroblasts and monocytes J. Cell Biol. 99 870-4 (Pubitemid 14043344)
190. Seo N, Russell B H, Rivera J J, Liang X, Xu X, Afshar-Kharghan V and Höök M 2010 An engineered alpha1 integrin-binding collagenous sequence J. Biol. Chem. 285 31046-54
191. Shi J, Lua S, Du N, Liu X and Song J 2008 Identification, recombinant production and structural characterization of four silk proteins from the Asiatic honeybee Apis Cerana Biomaterials 29 2820-8
192. Smith M C, Burns N, Sayers J R, Sorrell J A, Casjens S R and Hendrix R W 1998 Bacteriophage collagen Science 279 1834
193. Sponner A, Unger E, Grosse F and Weisshart K 2004 Conserved C-termini of Spidroins are secreted by the major ampullate glands and retained in the silk thread Biomacromolecules 5 840-5
194. Starcher B and Percival S 1985 Elastin turnover in the rat uterus Connect. Tissue Res. 13 207-15
195. Stark M, Grip S, Rising A, Hedhammar M, Engström W, Hjälm G and Johansson J 2007 Macroscopic fibers self-assembled from recombinant miniature spider silk proteins Biomacromolecules 8 1695-701 (Pubitemid 46865144)
196. Stein H, Wilensky M, Tsafrir Y, Rosenthal M, Amir R, Avraham T, Ofir K, Dgany O, Yayon A and Shoseyov O 2009 Production of bioactive, post-translationally modified, heterotrimeric, human recombinant type-I collagen in transgenic tobacco Biomacromolecules 10 2640-5
197. Stone P J, Morris S M, Griffin S, Mithieux S and Weiss A S 2001 Building Elastin. Incorporation of recombinant human tropoelastin into extracellular matrices using nonelastogenic rat-1 fibroblasts as a source for lysyl oxidase Am. J. Respir. Cell. Mol. Biol. 24 733-9 (Pubitemid 32550596)
198. Sutherland T D, Campbell P M, Weisman S, Trueman H E, Sriskantha A, Wanjura W J and Haritos V S 2006 A highly divergent gene cluster in honey bees encodes a novel silk family Genome Res. 16 1414-21 (Pubitemid 44664684)
199. Sutherland T D, Church J S, Hu X, Huson M G, Kaplan D L and Weisman S 2011 Single honeybee silk protein mimics properties of multi-protein silk PLoS One 6 e16489
200. Sutherland T D, Young J H, Weisman S, Hayashi C Y and Merritt D J 2010 Insect silk: one name, many materials Annu. Rev. Entomol. 55 171-88
201. Sutter M, Siepmann J, Hennink W E and Jiskoot W 2007 Recombinant gelatin hydrogels for the sustained release of proteins J. Conrol. Release 119 301-12 (Pubitemid 46783840)
202. Swanson B O, Blackledge T A, Summers A P and Hayashi C Y 2006 Spider dragline silk: correlated and mosaic evolution in high-performance biological materials Evolution 60 2539-51
203. Sweeney S M et al 2008 Candidate cell and matrix interaction domains on the collagen fibril, the predominant protein of vertebrates J. Biol. Chem. 283 21187-97
204. Sylvestre P, Couture-Tosi E and Mock M 2002 A collagen-like surface glycoprotein is a structural component of the Bacillus anthracis exosporium Mol. Microbiol. 45 169-78 (Pubitemid 35025942)
205. Tamura T, Kanda T, Takiya S, Okano K and Maekawa H 1990 Transient expression of chimeric CAT genes injected into early embryos of the domesticated silkworm Bombyx mori Japan J. Genet. 65 401-10
206. Teles H, Vermonden T, Eggink G, Hennink W E and de Wolf F A 2010 Hydrogels of collagen-inspired telechelic triblock copolymers for the sustained release of proteins J. Control. Release 147 298-303
207. Teng W, Cappello J and Wu X 2009 Recombinant silk-elastinlike protein polymer displays elasticity comparable to elastin Biomacromolecules 10 3028-36
208. Toman P D et al 2000 Production of recombinant human type I procollagen trimers using a four-gene expression system in the yeast Saccharomyces cerevisiae J. Biol. Chem. 275 23303-9 (Pubitemid 30646231)
209. Toman P D, Pieper F, Sakai N, Karatzas C, Platenburg E, de Wit I, Samuel C, Dekker A, Daniels G A, Berg R A and Platenburg G J 1999 Production of recombinant human type I procollagen homotrimer in the mammary gland of transgenic mice Transgenic Res. 8 415-27 (Pubitemid 30170496)
210. Tomita M 2011 Transgenic silkworms that weave recombinant proteins into silk cocoons Biotechnol. Lett. 33 645-54
211. Tomita M, Munetsuna H, Sato T, Adachi T, Hino R, Hayashi M, Shimizu K, Nakamura N, Tamura T and Yoshizato K 2003 Transgenic silkworms produce recombinant human type III procollagen in cocoons Nat. Biotechnol. 21 52-6 (Pubitemid 36055827)
212. Toonkool P, Jensen S A, Maxwell A L and Weiss A S 2001 Hydrophobic domains of human tropoelastin interact in a context-dependent manner J. Biol. Chem. 276 44575-80
213. Urry D W, Pattanaik A, Xu J, Woods T C, McPherson D T and Parker T M 1998 Elastic protein-based polymers in soft tissue augmentation and generation J. Biomater. Sci. Polym. Ed. 9 1015-48 (Pubitemid 28468397)
214. Van den Bergh F, Fu C L, Olague-Marchan M and Giudice G J 2006 The NC16A domain of collagen XVII plays a role in triple helix assembly and stability Biochem. Biophys. Res. Commun. 350 1032-7 (Pubitemid 44584196)
215. Vaughan P R, Galanis M, Richards K M, Tebb T A, Ramshaw J A and Werkmeister J A 1998 Production of recombinant hydroxylated human type III collagen fragment in Saccharomyces cerevisiae DNA Cell Biol. 17 511-8 (Pubitemid 28317210)
216. Veit G, Kobbe B, Keene D R, Paulsson M, Koch M and Wagener R 2006 Collagen XXVIII, a novel von Willebrand factor A domain-containing protein with many imperfections in the collagenous domain J. Biol. Chem. 281 3494-504 (Pubitemid 43845965)
217. Vendrely C and Scheibel T 2007 Biotechnological production of spider-silk proteins enables new applications Macromol. Biosci. 7 401-9 (Pubitemid 47237515)
218. Vepari C and Kaplan D L 2007 Silk as a biomaterial Prog. Polym. Sci. 32 991-1007 (Pubitemid 47198292)
219. Vieth S, Bellingham C M, Keeley F W, Hodge S M and Rousseau D 2007 Microstructural and tensile properties of elastin-based polypeptides crosslinked with genipin and pyrroloquinoline quinone Biopolymers 85 199-206
220. Vollrath F 2000 Strength and structure of spiders' silks J. Biotechnol. 74 67-83
221. Vollrath F and Knight D P 2001 Liquid crystalline spinning of spider silk Nature 410 541-8 (Pubitemid 32267190)
222. Vrhovski B and Weiss A S 1998 Biochemistry of tropoelastin Eur. J. Biochem. 258 1-18 (Pubitemid 28538302)
223. Wang C and St. Leger R J 2006 A collagenous protective coat enables Metarhizium anisopliae to evade insect immune responses Proc. Natl Acad. Sci. USA 103 6647-52
224. Wang M, Jin H J, Kaplan D L and Rutledge G C 2004 Mechanical properties of electrospun silk fibers Macromolecules 37 6856-64
225. Weis-Fogh T 1960 A rubber-like protein in insect cuticle J. Exp. Biol. 37 889-907
226. Welsh E R and Tirrell D A 2000 Engineering the extracellular matrix: a novel approach to polymeric biomaterials: I. Control of the physical properties of artificial protein matrices designed to support adhesion of vascular endothelial cells Biomacromolecules 1 23-30
227. Wen H, Lan X, Zhang Y, Zhao T, Wang Y, Kajiura Z and Nakagaki M 2010 Transgenic silkworms (Bombyx mori) produce recombinant spider dragline silk in cocoons Mol. Biol. Rep. 37 1815-21
228. Werkmeister J A and Ramshaw J A M 2000 Immunology of collagen-based biomaterials Handbook of Biomaterials Engineering, ed D L Wise (New York: Dekker) pp 739-59
229. Werkmeister J A, Vaughan P R, Peng Y, Ramshaw J A M, Wise D L, Hasirci V, Lewandrowski K U, Yaszemski M J, Altobelli D E and Trantolo D J 2003 Recombinant protein scaffolds for tissue engineering Biomaterials Handbook - Advanced Applications of Basic Sciences and Bioengineering (New York: Dekker) pp 677-99
230. Werten M W, Teles H, Moers A P, Wolbert E J, Sprakel J, Eggink G and de Wolf F A 2009 Precision gels from collagen-inspired triblock copolymers Biomacromolecules 10 1106-13
231. White J F, Werkmeister J, Hilbert S L and Ramshaw J A M 2010 Heart valve collagens: cross-species comparison using immunohistological methods J. Heart Valve Dis. 19 766-71
232. Widhe M, Bysell H, Nystedt S, Schenning I, Malmsten M, Johansson J, Rising A and Hedhammar M 2010 Recombinant spider silk as matrices for cell culture Biomaterials 31 9575-85
233. Williams D J and Sebastine I M 2005 Tissue engineering and regenerative medicine: manufacturing challenges IEE Proc. Nanobiotechnol. 152 207-10
234. Williams J I, Salerno A J, Goldberg I and McAllister W T 1988 Microbial production of peptide oligomers Patent. International Publication Number WO 88/05082
235. Williams K E and Olsen D R 2009 Matrix metalloproteinase-1 cleavage site recognition and binding in full-length human type III collagen Matrix Biol. 28 373-9
236. Wittmer C R, Hu X, Gauthier P C, Weisman S, Kaplan D L and Sutherland T D 2011 Production, structure and in vitro degradation of electrospun honeybee silk nanofibers Acta Biomater. 7 3789-95
237. Woodhouse K A, Klement P, Chen V, Gorbet M B, Keeley F W, Stahl R, Fromstein J D and Bellingham C M 2004 Investigation of recombinant human elastin polypeptides as non-thrombogenic coatings Biomaterials 25 4543-53 (Pubitemid 38561141)
238. Wu B, Zheng Q, Guo X, Wu Y, Wang Y and Cui F 2008 Preparation and ectopic osteogenesis in vivo of scaffold based on mineralized recombinant human-like collagen loaded with synthetic BMP-2-derived peptide Biomed. Mater. 3 044111
239. Wurm F M 2003 Human therapeutic proteins from silkworms Nat. Biotechnol. 21 34-5 (Pubitemid 36055822)
240. Xi C, Tan L, Sun Y, Liang F, Liu N, Xue H, Luo Y, Yuan F, Sun Y and Xi Y 2009 A novel recombinant peptide containing only two T-cell tolerance epitopes of chicken type II collagen that suppresses collagen-induced arthritis Mol. Immunol. 46 729-37
241. Xia X X, Qian Z G, Ki C S, Park Y H, Kaplan D L and Lee S Y 2010 Native-sized recombinant spider silk protein produced in metabolically engineered Escherichia coli results in a strong fiber Proc. Natl Acad. Sci. USA 107 14059-63
242. Xu C, Yu Z, Inouye M, Brodsky B and Mirochnitchenko O 2010 Expanding the family of collagen proteins: recombinant bacterial collagens of varying composition form triple-helices of similar stability Biomacromolecules 11 348-56
243. Xu H T et al 2007 Construct synthetic gene encoding artificial spider dragline silk protein and its expression in milk of transgenic mice Anim. Biotechnol. 18 1-12
244. Xu M and Lewis R V 1990 Structure of a protein superfiber: spider dragline silk Proc. Natl Acad. Sci. USA 87 7120-4
245. 2 pulses Biotechnol. Lett. 31 221-6
246. Xue W, Fan D, Shang L, Zhu C, Ma X, Zhu X and Yu Y 2010 Effects of acetic acid and its assimilation in fed-batch cultures of recombinant Escherichia coli containing human-like collagen cDNA J. Biosci. Bioeng. 109 257-61
247. Yamada K, Yamaura J, Katoh M, Hata K, Okuda K and Yoshie H 2006 Fabrication of cultured oral gingiva by tissue engineering techniques without materials of animal origin J. Periodontol. 77 672-7 (Pubitemid 44725053)
248. Yanagisawa S, Zhu Z, Kobayashi I, Uchino K, Tamada Y, Tamura T and Asakura T 2007 Improving cell-adhesive properties of recombinant Bombyx mori silk by incorporation of collagen or fibronectin derived peptides produced by transgenic silkworms Biomacromolecules 8 3487-92 (Pubitemid 350193749)
249. Yang M, Muto T, Knight D, Collins A M and Asakura T 2008a Synthesis and characterization of silklike materials containing the calcium-binding sequence from calbindin D9k or the shell nacreous matrix protein MSI60 Biomacromolecules 9 416-20
250. Yang M, Tanaka C, Yamauchi K, Ohgo K, Kurokawa M and Asakura T 2008b Silklike materials constructed from sequences of Bombyx mori silk fibroin, fibronectin, and elastin J. Biomed. Mater. Res. A 84 353-63
251. Yang W, Chan V C, Kirkpatrick A, Ramshaw J A and Brodsky B 1997 Gly-Pro-Arg confers stability similar to Gly-Pro-Hyp in the collagen triple-helix of host-guest peptides J. Biol. Chem. 272 28837-40 (Pubitemid 27498161)
252. Yao J and Asakura T 2003 Synthesis and structural characterization of silk-like materials incorporated with an elastic motif J. Biochem. 133 147-54 (Pubitemid 36240990)
253. Yoo M K, Kweon H Y, Lee K G, Lee H C and Cho C S 2004 Preparation of semi-interpenetrating polymer networks composed of silk fibroin and poloxamer macromer Int. J. Biol. Macromol. 34 263-70 (Pubitemid 39220862)
254. Yoshizumi A, Yu Z, Silva T, Thiagarajan G, Ramshaw J A, Inouye M and Brodsky B 2009 Self-association of streptococcus pyogenes collagen-like constructs into higher order structures Protein Sci. 18 1241-51
255. Young D and Bennet-Clark H 1995 The role of the tymbal in cicada sound production J. Exp. Biol. 198 1001-20
256. Zhang C, Baez J and Glatz C E 2009a Purification and characterization of a 44-kDa recombinant collagen I alpha 1 fragment from corn grain J. Agric. Food Chem. 57 880-7
257. Zhang C, Baez J, Pappu K M and Glatz C E 2009b Purification and characterization of a transgenic corn grain-derived recombinant collagen type I alpha 1 Biotechnol. Prog. 25 1660-8
258. Zhang Y Q 2002 Applications of natural silk protein sericin in biomaterials Biotechnol. Adv. 20 91-100
259. Zhou C Z, Confalonieri F, Jacquet M, Perasso R, Li Z G and Janin J 2001 Silk fibroin: structural implications of a remarkable amino acid sequence Proteins 44 119-22
260. Zhou C Z, Confalonieri F, Medina N, Zivanovic Y, Esnault C, Yang T, Jacquet M, Janin J, Duguet M, Perasso R and Li Z G 2000 Fine organization of Bombyx mori fibroin heavy chain gene Nucl. Acid Res. 28 2413-9 (Pubitemid 30349048)
261. Zuckerkandl E and Pauling L 1965 Molecules as documents of evolutionary history J. Theor. Biol. 8 357-66