The generation of germline transgenic silkworms for the production of biologically active recombinant fusion proteins of fibroin and human basic fibroblast growth factor

Biomaterials

Volumn 27, Issue 33, 2006, Pages 5715-5724

  Hino, Rika ^a   Tomita, Masahiro ^a   Yoshizato, Katsutoshi ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Bioactive fibroin; Human fibroblast growth factor; Human umbilical vein endothelial cells; Scaffold; Silk; Transgenic silkworms

Indexed keywords

BIOACTIVE FIBROIN; HUMAN FIBROBLAST GROWTH FACTOR; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; TRANSGENIC SILKWORMS;

ANIMAL CELL CULTURE; GENES; PROTEINS; SILK;

GENETIC ENGINEERING;

ALCOHOL; BIOMATERIAL; CALCIUM CHLORIDE; FIBROIN HUMAN FIBROBLAST GROWTH FACTOR FUSION PROTEIN; GENE PRODUCT; GLUTATHIONE; HYBRID PROTEIN; SERICIN; TRYPSIN; UNCLASSIFIED DRUG; WATER;

ANIMAL TISSUE; ARTICLE; BIOLOGICAL ACTIVITY; CELL CULTURE; CELL GROWTH; CONTROLLED STUDY; CULTURE MEDIUM; DNA FLANKING REGION; DRUG ACTIVITY; EMBRYO; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; LIGHT CHAIN; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FOLDING; PROTEIN IMMOBILIZATION; SILKWORM; SOLUBILIZATION; SOLUTION AND SOLUBILITY; TISSUE ENGINEERING; TRANSGENIC ANIMAL; UMBILICAL VEIN; WESTERN BLOTTING;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BOMBYX; CELLS, CULTURED; CULTURE MEDIA; FIBROBLAST GROWTH FACTOR 2; FIBROINS; GERM CELLS; HUMANS; RECOMBINANT FUSION PROTEINS; SILK;

GENES; GENETIC ENGINEERING; PROTEINS; SILK;

EID: 33747767940     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2006.07.028     Document Type: Article

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