메뉴 건너뛰기




Volumn 62, Issue 15, 2010, Pages 1509-1523

Silk-elastinlike protein polymers for matrix-mediated cancer gene therapy

Author keywords

Gene delivery; Hydrogels; Recombinant polymers; Silk elastinlike protein polymers; Viral directed enzyme prodrug therapy

Indexed keywords

CANCER GENE THERAPY; CONTROLLED RELEASE SYSTEMS; GENE DELIVERY; INTRATUMORAL GENE DELIVERY; MATRIX; MONODISPERSE; PLASMID DNA; RECOMBINANT POLYMERS; SILK FIBROIN; SILK-ELASTINLIKE PROTEIN POLYMERS; SYNTHESIS AND CHARACTERIZATIONS; VIRAL DIRECTED ENZYME PRODRUG THERAPY;

EID: 78649876131     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.addr.2010.04.006     Document Type: Review
Times cited : (74)

References (58)
  • 1
    • 63849199884 scopus 로고    scopus 로고
    • Bioresponsive polymers for nonviral gene delivery
    • Yu H., Wagner E. Bioresponsive polymers for nonviral gene delivery. Curr Opin Mol Ther 2009, 11:165-178.
    • (2009) Curr Opin Mol Ther , vol.11 , pp. 165-178
    • Yu, H.1    Wagner, E.2
  • 2
    • 34247855110 scopus 로고    scopus 로고
    • Nonviral gene delivery: what we know and what is next
    • Gao X., Kim K.S., Liu D. Nonviral gene delivery: what we know and what is next. AAPS J 2007, 9:E92-E104.
    • (2007) AAPS J , vol.9
    • Gao, X.1    Kim, K.S.2    Liu, D.3
  • 3
    • 64549134676 scopus 로고    scopus 로고
    • Nonviral vectors for gene delivery
    • Mintzer M.A., Simanek E.E. Nonviral vectors for gene delivery. Chem. Rev. 2009, 109:259-302.
    • (2009) Chem. Rev. , vol.109 , pp. 259-302
    • Mintzer, M.A.1    Simanek, E.E.2
  • 4
    • 0035828388 scopus 로고    scopus 로고
    • Survival and recurrence after concomitant chemotherapy and radiotherapy for cancer of the uterine cervix: a systematic review and meta-analysis
    • Green J.A., Kirwan J.M., Tierney J.F., Symonds P., Fresco L., Collingwood M., Williams C.J. Survival and recurrence after concomitant chemotherapy and radiotherapy for cancer of the uterine cervix: a systematic review and meta-analysis. Lancet 2001, 358:781-786.
    • (2001) Lancet , vol.358 , pp. 781-786
    • Green, J.A.1    Kirwan, J.M.2    Tierney, J.F.3    Symonds, P.4    Fresco, L.5    Collingwood, M.6    Williams, C.J.7
  • 5
    • 0029876301 scopus 로고    scopus 로고
    • Endocrinological late effects after chemotherapy for testicular cancer
    • Berger C.C., Bokemeyer C., Schuppert F., Schmoll H.J. Endocrinological late effects after chemotherapy for testicular cancer. Br. J. Cancer 1996, 73:1108-1114.
    • (1996) Br. J. Cancer , vol.73 , pp. 1108-1114
    • Berger, C.C.1    Bokemeyer, C.2    Schuppert, F.3    Schmoll, H.J.4
  • 6
    • 0029805736 scopus 로고    scopus 로고
    • Evaluation of long-term toxicity after chemotherapy for testicular cancer
    • Bokemeyer C., Berger C.C., Kuczyk M.A., Schmoll H.J. Evaluation of long-term toxicity after chemotherapy for testicular cancer. J Clin Oncol 1996, 14:2923-2932.
    • (1996) J Clin Oncol , vol.14 , pp. 2923-2932
    • Bokemeyer, C.1    Berger, C.C.2    Kuczyk, M.A.3    Schmoll, H.J.4
  • 7
    • 0021330174 scopus 로고
    • The carcinogenic potential of cytotoxic chemotherapy and its implications for therapeutic decision-making
    • Carter S.K. The carcinogenic potential of cytotoxic chemotherapy and its implications for therapeutic decision-making. Cancer Chemother. Pharmacol. 1984, 12:67-69.
    • (1984) Cancer Chemother. Pharmacol. , vol.12 , pp. 67-69
    • Carter, S.K.1
  • 8
    • 0017834226 scopus 로고
    • Is chemotherapy carcinogenic?
    • Rosner F. Is chemotherapy carcinogenic?. CA Cancer J. Clin. 1978, 28:57-59.
    • (1978) CA Cancer J. Clin. , vol.28 , pp. 57-59
    • Rosner, F.1
  • 11
    • 77952673515 scopus 로고    scopus 로고
    • Fibrin-mediated lentivirus gene transfer: Implications for lentivirus microarrays
    • Raut S.D., Lei P., Padmashali R.M., Andreadis S.T. Fibrin-mediated lentivirus gene transfer: Implications for lentivirus microarrays. J. Control Release 2010, 144:213-220.
    • (2010) J. Control Release , vol.144 , pp. 213-220
    • Raut, S.D.1    Lei, P.2    Padmashali, R.M.3    Andreadis, S.T.4
  • 13
    • 24744454661 scopus 로고    scopus 로고
    • A novel method for viral gene delivery in solid tumors
    • Wang Y., Liu S., Li C.Y., Yuan F. A novel method for viral gene delivery in solid tumors. Cancer Res. 2005, 65:7541-7545.
    • (2005) Cancer Res. , vol.65 , pp. 7541-7545
    • Wang, Y.1    Liu, S.2    Li, C.Y.3    Yuan, F.4
  • 14
    • 1242289002 scopus 로고    scopus 로고
    • Systemic dissemination of viral vectors during intratumoral injection
    • Wang Y., Hu J.K., Krol A., Li Y.P., Li C.Y., Yuan F. Systemic dissemination of viral vectors during intratumoral injection. Mol Cancer Ther 2003, 2:1233-1242.
    • (2003) Mol Cancer Ther , vol.2 , pp. 1233-1242
    • Wang, Y.1    Hu, J.K.2    Krol, A.3    Li, Y.P.4    Li, C.Y.5    Yuan, F.6
  • 15
    • 0036328129 scopus 로고    scopus 로고
    • Swelling behavior of a genetically engineered silk-elastinlike protein polymer hydrogel
    • Dinerman A.A., Cappello J., Ghandehari H., Hoag S.W. Swelling behavior of a genetically engineered silk-elastinlike protein polymer hydrogel. Biomaterials 2002, 23:4203-4210.
    • (2002) Biomaterials , vol.23 , pp. 4203-4210
    • Dinerman, A.A.1    Cappello, J.2    Ghandehari, H.3    Hoag, S.W.4
  • 16
    • 0035997328 scopus 로고    scopus 로고
    • Controlled release of plasmid DNA from a genetically engineered silk-elastinlike hydrogel
    • Megeed Z., Cappello J., Ghandehari H. Controlled release of plasmid DNA from a genetically engineered silk-elastinlike hydrogel. Pharm. Res. 2002, 19:954-959.
    • (2002) Pharm. Res. , vol.19 , pp. 954-959
    • Megeed, Z.1    Cappello, J.2    Ghandehari, H.3
  • 17
    • 1642441833 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of recombinant silk-elastinlike hydrogels for cancer gene therapy
    • Megeed Z., Haider M., Li D., O'Malley B.W., Cappello J., Ghandehari H. In vitro and in vivo evaluation of recombinant silk-elastinlike hydrogels for cancer gene therapy. J Control Release 2004, 94:433-445.
    • (2004) J Control Release , vol.94 , pp. 433-445
    • Megeed, Z.1    Haider, M.2    Li, D.3    O'Malley, B.W.4    Cappello, J.5    Ghandehari, H.6
  • 18
    • 23844504675 scopus 로고    scopus 로고
    • Molecular engineering of silk-elastinlike polymers for matrix-mediated gene delivery: biosynthesis and characterization
    • Haider M., Leung V., Ferrari F., Crissman J., Powell J., Cappello J., Ghandehari H. Molecular engineering of silk-elastinlike polymers for matrix-mediated gene delivery: biosynthesis and characterization. Mol Pharm 2005, 2:139-150.
    • (2005) Mol Pharm , vol.2 , pp. 139-150
    • Haider, M.1    Leung, V.2    Ferrari, F.3    Crissman, J.4    Powell, J.5    Cappello, J.6    Ghandehari, H.7
  • 19
    • 33947143774 scopus 로고    scopus 로고
    • Adenoviral gene delivery to solid tumors by recombinant silk-elastinlike protein polymers
    • Hatefi A., Cappello J., Ghandehari H. Adenoviral gene delivery to solid tumors by recombinant silk-elastinlike protein polymers. Pharm. Res. 2007, 24:773-779.
    • (2007) Pharm. Res. , vol.24 , pp. 773-779
    • Hatefi, A.1    Cappello, J.2    Ghandehari, H.3
  • 20
    • 56049100274 scopus 로고    scopus 로고
    • Characterization and real-time imaging of gene expression of adenovirus embedded silk-elastinlike protein polymer hydrogels
    • Cresce A.W., Dandu R., Burger A., Cappello J., Ghandehari H. Characterization and real-time imaging of gene expression of adenovirus embedded silk-elastinlike protein polymer hydrogels. Mol Pharm 2008, 5:891-897.
    • (2008) Mol Pharm , vol.5 , pp. 891-897
    • Cresce, A.W.1    Dandu, R.2    Burger, A.3    Cappello, J.4    Ghandehari, H.5
  • 21
    • 37249011202 scopus 로고    scopus 로고
    • Characterization of structurally related adenovirus-laden silk-elastinlike hydrogels
    • Dandu R., Ghandehari H., Cappello J. Characterization of structurally related adenovirus-laden silk-elastinlike hydrogels. J. of Bioactive and Compatible Polymers 2008, 23:5-19.
    • (2008) J. of Bioactive and Compatible Polymers , vol.23 , pp. 5-19
    • Dandu, R.1    Ghandehari, H.2    Cappello, J.3
  • 22
    • 58149203183 scopus 로고    scopus 로고
    • Silk-elastinlike protein polymer hydrogels: Influence of monomer sequence on physicochemical properties
    • Dandu R., Cresce A.V., Briber R., Dowell P., Cappello J., Ghandehari H. Silk-elastinlike protein polymer hydrogels: Influence of monomer sequence on physicochemical properties. Polymer 2009, 50:366-374.
    • (2009) Polymer , vol.50 , pp. 366-374
    • Dandu, R.1    Cresce, A.V.2    Briber, R.3    Dowell, P.4    Cappello, J.5    Ghandehari, H.6
  • 23
    • 58949097522 scopus 로고    scopus 로고
    • Influence of polymer structure and biodegradation on DNA release from silk-elastinlike protein polymer hydrogels
    • Hwang D., Moolchandani V., Dandu R., Haider M., Cappello J., Ghandehari H. Influence of polymer structure and biodegradation on DNA release from silk-elastinlike protein polymer hydrogels. Int J Pharm 2009, 368:215-219.
    • (2009) Int J Pharm , vol.368 , pp. 215-219
    • Hwang, D.1    Moolchandani, V.2    Dandu, R.3    Haider, M.4    Cappello, J.5    Ghandehari, H.6
  • 25
    • 70449698522 scopus 로고    scopus 로고
    • Silk-elastinlike recombinant polymers for gene therapy of head and neck cancer: from molecular definition to controlled gene expression
    • Gustafson J., Greish K., Frandsen J., Cappello J., Ghandehari H. Silk-elastinlike recombinant polymers for gene therapy of head and neck cancer: from molecular definition to controlled gene expression. J Control Release 2009, 140:256-261.
    • (2009) J Control Release , vol.140 , pp. 256-261
    • Gustafson, J.1    Greish, K.2    Frandsen, J.3    Cappello, J.4    Ghandehari, H.5
  • 26
    • 77955236873 scopus 로고    scopus 로고
    • Silk-elastinlike recombinant polymers improve the efficacy of adenovirus thymidine kinase enzyme prodrug therapy of head and neck tumors
    • Greish K., Frandsen J., Scharf S., Gustafson J., Cappello J., Ghandehari H. Silk-elastinlike recombinant polymers improve the efficacy of adenovirus thymidine kinase enzyme prodrug therapy of head and neck tumors. J. Gene Med. 2010, 12:572-579.
    • (2010) J. Gene Med. , vol.12 , pp. 572-579
    • Greish, K.1    Frandsen, J.2    Scharf, S.3    Gustafson, J.4    Cappello, J.5    Ghandehari, H.6
  • 27
    • 78349293855 scopus 로고    scopus 로고
    • Influence of solute charge and hydrophobicity on partitioning and diffusion in a genetically engineered silk-elastinlike protein polymer hydrogel
    • Dinerman A., Cappello J., El-Sayed M., Hoag S.W., Ghandehari H. Influence of solute charge and hydrophobicity on partitioning and diffusion in a genetically engineered silk-elastinlike protein polymer hydrogel. Macromolecular Bioscience 2010, 10:1235-1247.
    • (2010) Macromolecular Bioscience , vol.10 , pp. 1235-1247
    • Dinerman, A.1    Cappello, J.2    El-Sayed, M.3    Hoag, S.W.4    Ghandehari, H.5
  • 29
    • 0001087383 scopus 로고
    • The amino acid sequence in a fraction of the fibroin of Bombyx mori
    • Lucas F., Shaw J.T., Smith S.G. The amino acid sequence in a fraction of the fibroin of Bombyx mori. Biochem. J. 1957, 66:468-479.
    • (1957) Biochem. J. , vol.66 , pp. 468-479
    • Lucas, F.1    Shaw, J.T.2    Smith, S.G.3
  • 30
    • 0019491077 scopus 로고
    • Elastin structure, biosynthesis, and relation to disease states
    • Sandberg L.B., Soskel N.T., Leslie J.G. Elastin structure, biosynthesis, and relation to disease states. N Engl J Med 1981, 304:566-579.
    • (1981) N Engl J Med , vol.304 , pp. 566-579
    • Sandberg, L.B.1    Soskel, N.T.2    Leslie, J.G.3
  • 31
    • 0002915441 scopus 로고
    • Microbial production of structural protein polymers
    • Hanser, Munich, D.P. Mobley (Ed.)
    • Cappello J., Ferrari F. Microbial production of structural protein polymers. Plastics from Microbes 1994, 35-92. Hanser, Munich. D.P. Mobley (Ed.).
    • (1994) Plastics from Microbes , pp. 35-92
    • Cappello, J.1    Ferrari, F.2
  • 32
    • 0002919179 scopus 로고    scopus 로고
    • Genetically engineered protein polymers
    • Harwood Academic Publishers, Amsterdam, A. Domb, J. Kost, D. Wiseman (Eds.)
    • Cappello J. Genetically engineered protein polymers. Handbook of Biodegradable Polymers 1997, 387-416. Harwood Academic Publishers, Amsterdam. A. Domb, J. Kost, D. Wiseman (Eds.).
    • (1997) Handbook of Biodegradable Polymers , pp. 387-416
    • Cappello, J.1
  • 33
    • 0000251981 scopus 로고    scopus 로고
    • Synthetically designed protein polymer biomaterials
    • American Chemical Society, Washington, DC, K. Park (Ed.)
    • Cappello J. Synthetically designed protein polymer biomaterials. Controlled Drug Delivery: Challenges and Strategies 1997, 439-453. American Chemical Society, Washington, DC. K. Park (Ed.).
    • (1997) Controlled Drug Delivery: Challenges and Strategies , pp. 439-453
    • Cappello, J.1
  • 35
    • 0037130997 scopus 로고    scopus 로고
    • Genetically engineered silk-elastinlike protein polymers for controlled drug delivery
    • Megeed Z., Cappello J., Ghandehari H. Genetically engineered silk-elastinlike protein polymers for controlled drug delivery. Adv Drug Deliv Rev 2002, 54:1075-1091.
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 1075-1091
    • Megeed, Z.1    Cappello, J.2    Ghandehari, H.3
  • 36
    • 0842287605 scopus 로고    scopus 로고
    • Genetically engineered polymers: status and prospects for controlled release
    • Haider M., Megeed Z., Ghandehari H. Genetically engineered polymers: status and prospects for controlled release. J Control Release 2004, 95:1-26.
    • (2004) J Control Release , vol.95 , pp. 1-26
    • Haider, M.1    Megeed, Z.2    Ghandehari, H.3
  • 37
    • 28444441368 scopus 로고    scopus 로고
    • Genetically engineered protein-based polymers: potential in gene delivery
    • CRC Press, Boca Raton, FL, M. Amiji (Ed.)
    • Megeed Z., Ghandehari H. Genetically engineered protein-based polymers: potential in gene delivery. Polymeric Gene Delivery: Principles and Applications 2005, 489-507. CRC Press, Boca Raton, FL. M. Amiji (Ed.).
    • (2005) Polymeric Gene Delivery: Principles and Applications , pp. 489-507
    • Megeed, Z.1    Ghandehari, H.2
  • 38
    • 78649846667 scopus 로고    scopus 로고
    • Recombinant polymers for drug delivery
    • Marcel Dekker, Inc, New York, NY, G. Kwon (Ed.)
    • Megeed Z., Ghandehari H. Recombinant polymers for drug delivery. Polymeric Drug Delivery Systems 2005, 415-452. Marcel Dekker, Inc, New York, NY. G. Kwon (Ed.).
    • (2005) Polymeric Drug Delivery Systems , pp. 415-452
    • Megeed, Z.1    Ghandehari, H.2
  • 40
    • 28444489992 scopus 로고    scopus 로고
    • Recombinant polymers for cancer gene therapy: a minireview
    • Haider M., Hatefi A., Ghandehari H. Recombinant polymers for cancer gene therapy: a minireview. J Control Release 2005, 109:108-119.
    • (2005) J Control Release , vol.109 , pp. 108-119
    • Haider, M.1    Hatefi, A.2    Ghandehari, H.3
  • 41
    • 34547587567 scopus 로고    scopus 로고
    • Delivery of bioactive agents from recombinant polymers
    • Dandu R., Ghandehari H. Delivery of bioactive agents from recombinant polymers. Prog. in Polymer Sci. 2007, 32:1008-1030.
    • (2007) Prog. in Polymer Sci. , vol.32 , pp. 1008-1030
    • Dandu, R.1    Ghandehari, H.2
  • 42
  • 44
    • 0037151322 scopus 로고    scopus 로고
    • Solute diffusion in genetically engineered silk-elastinlike protein polymer hydrogels
    • Dinerman A.A., Cappello J., Ghandehari H., Hoag S.W. Solute diffusion in genetically engineered silk-elastinlike protein polymer hydrogels. J. of Control. Release 2002, 82:277-287.
    • (2002) J. of Control. Release , vol.82 , pp. 277-287
    • Dinerman, A.A.1    Cappello, J.2    Ghandehari, H.3    Hoag, S.W.4
  • 45
    • 70449447979 scopus 로고    scopus 로고
    • Surface induced nanofiber growth by self-assembly of a silk-elastin-like protein polymer
    • Hwang W., Kim B.H., Dandu R., Cappello J., Ghandehari H., Seog J. Surface induced nanofiber growth by self-assembly of a silk-elastin-like protein polymer. Langmuir 2009, 25:12682-12686.
    • (2009) Langmuir , vol.25 , pp. 12682-12686
    • Hwang, W.1    Kim, B.H.2    Dandu, R.3    Cappello, J.4    Ghandehari, H.5    Seog, J.6
  • 46
    • 0037819879 scopus 로고    scopus 로고
    • Hierarchical assembly of beta2-microglobulin amyloid in vitro revealed by atomic force microscopy
    • Kad N.M., Myers S.L., Smith D.P., Smith D.A., Radford S.E., Thomson N.H. Hierarchical assembly of beta2-microglobulin amyloid in vitro revealed by atomic force microscopy. J Mol Biol 2003, 330:785-797.
    • (2003) J Mol Biol , vol.330 , pp. 785-797
    • Kad, N.M.1    Myers, S.L.2    Smith, D.P.3    Smith, D.A.4    Radford, S.E.5    Thomson, N.H.6
  • 47
    • 22244439242 scopus 로고    scopus 로고
    • The aggregation kinetics of Alzheimer's beta-amyloid peptide is controlled by stochastic nucleation
    • Hortschansky P., Schroeckh V., Christopeit T., Zandomeneghi G., Fandrich M. The aggregation kinetics of Alzheimer's beta-amyloid peptide is controlled by stochastic nucleation. Protein Sci. 2005, 14:1753-1759.
    • (2005) Protein Sci. , vol.14 , pp. 1753-1759
    • Hortschansky, P.1    Schroeckh, V.2    Christopeit, T.3    Zandomeneghi, G.4    Fandrich, M.5
  • 48
    • 0037020259 scopus 로고    scopus 로고
    • Kinetic studies of amyloid beta-protein fibril assembly. Differential effects of alpha-helix stabilization
    • Fezoui Y., Teplow D.B. Kinetic studies of amyloid beta-protein fibril assembly. Differential effects of alpha-helix stabilization. J Biol Chem 2002, 277:36948-36954.
    • (2002) J Biol Chem , vol.277 , pp. 36948-36954
    • Fezoui, Y.1    Teplow, D.B.2
  • 49
    • 62649168361 scopus 로고    scopus 로고
    • Irena: tool suite for modeling and analysis of small-angle scattering
    • Ilavsky J., Jemian P.R. Irena: tool suite for modeling and analysis of small-angle scattering. J. Appl. Cryst. 2009, 42:347-353.
    • (2009) J. Appl. Cryst. , vol.42 , pp. 347-353
    • Ilavsky, J.1    Jemian, P.R.2
  • 51
    • 22044443171 scopus 로고    scopus 로고
    • Scaling behaviour of PAMAM dendrimers determined by diffusion NMR
    • Fritzinger B., Scheler U. Scaling behaviour of PAMAM dendrimers determined by diffusion NMR. Macromol Chem Physic 2005, 206:1288-1291.
    • (2005) Macromol Chem Physic , vol.206 , pp. 1288-1291
    • Fritzinger, B.1    Scheler, U.2
  • 52
    • 0031806727 scopus 로고    scopus 로고
    • Effects of supercoiling in electrophoretic trapping of circular DNA in polyacrylamide gels
    • Akerman B. Effects of supercoiling in electrophoretic trapping of circular DNA in polyacrylamide gels. Biophys. J. 1998, 74:3140-3151.
    • (1998) Biophys. J. , vol.74 , pp. 3140-3151
    • Akerman, B.1
  • 53
    • 0017725069 scopus 로고
    • Physical properties and gel electrophoresis behavior of R12-derived plasmid DNAs
    • Mickel S., Arena V., Bauer W. Physical properties and gel electrophoresis behavior of R12-derived plasmid DNAs. Nucleic Acids Res. 1977, 4:1465-1482.
    • (1977) Nucleic Acids Res. , vol.4 , pp. 1465-1482
    • Mickel, S.1    Arena, V.2    Bauer, W.3
  • 55
    • 33745726938 scopus 로고    scopus 로고
    • Study of hepatotoxicity of naltrexone in the treatment of alcoholism
    • Yen M.H., Ko H.C., Tang F.I., Lu R.B., Hong J.S. Study of hepatotoxicity of naltrexone in the treatment of alcoholism. Alcohol 2006, 38:117-120.
    • (2006) Alcohol , vol.38 , pp. 117-120
    • Yen, M.H.1    Ko, H.C.2    Tang, F.I.3    Lu, R.B.4    Hong, J.S.5
  • 56
    • 0142089747 scopus 로고    scopus 로고
    • Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer
    • Raper S.E., Chirmule N., Lee F.S., Wivel N.A., Bagg A., Gao G.P., Wilson J.M., Batshaw M.L. Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer. Mol. Genet. Metab. 2003, 80:148-158.
    • (2003) Mol. Genet. Metab. , vol.80 , pp. 148-158
    • Raper, S.E.1    Chirmule, N.2    Lee, F.S.3    Wivel, N.A.4    Bagg, A.5    Gao, G.P.6    Wilson, J.M.7    Batshaw, M.L.8
  • 57
    • 0028937785 scopus 로고
    • Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
    • Yang Y., Li Q., Ertl H.C., Wilson J.M. Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses. J Virol 1995, 69:2004-2015.
    • (1995) J Virol , vol.69 , pp. 2004-2015
    • Yang, Y.1    Li, Q.2    Ertl, H.C.3    Wilson, J.M.4
  • 58
    • 0033373328 scopus 로고    scopus 로고
    • Variability of adenovirus receptor density influences gene transfer efficiency and therapeutic response in head and neck cancer
    • Li D., Duan L., Freimuth P., O'Malley B.W. Variability of adenovirus receptor density influences gene transfer efficiency and therapeutic response in head and neck cancer. Clin Cancer Res 1999, 5:4175-4181.
    • (1999) Clin Cancer Res , vol.5 , pp. 4175-4181
    • Li, D.1    Duan, L.2    Freimuth, P.3    O'Malley, B.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.