Elastin-mimetic protein polymers capable of physical and chemical crosslinking

Biomaterials

Volumn 30, Issue 3, 2009, Pages 409-422

  Sallach, Rory E ^a,b   Cui, Wanxing ^a   Wen, Jing ^a   Martinez, Adam ^a,b   Conticello, Vincent P ^b   Chaikof, Elliot L ^a,b,c  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

^c Georgia Institute of Technology   (United States)

Author keywords

In vivo biocompatibility; Mechanical testing; Protein polymer; Recombinant elastin mimetic

Indexed keywords

ABS RESINS; ALDEHYDES; BIOCOMPATIBILITY; CHEMICAL PROPERTIES; GLYCOPROTEINS; MATERIALS PROPERTIES; MECHANICAL TESTING; POLYMERS; SYNTHESIS (CHEMICAL);

CHEMICAL CROSSLINKING; CREEP STRAINS; FUNCTIONAL RESPONSES; GLUTARALDEHYDE; IN VIVO BIOCOMPATIBILITY; IN-VIVO; LOADING CONDITIONS; MICROPHASE; MORPHO-LOGIES; MULTIBLOCK SYSTEMS; NEW CLASSES; OPTIMAL CONTROLS; PHYSICAL CROSSLINKING; POTENTIAL PROPERTIES; PROTEIN ASSEMBLIES; PROTEIN POLYMER; PROTEIN POLYMERS; RECOMBINANT ELASTIN-MIMETIC; SPECIFIC DOMAINS; SYNTHESIS OF; TRIBLOCK CO POLYMERS;

CROSSLINKING;

COPOLYMER; DOUBLE STRANDED DNA; ELASTIN; GLUTARALDEHYDE; MONOMER; POLYMER; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOCOMPATIBILITY; CONTROLLED STUDY; CROSS LINKING; FILM; FLOW CYTOMETRY; FLOW KINETICS; FLUORESCENCE ACTIVATED CELL SORTING; FOREIGN BODY; HISTOLOGY; HYDRATION; HYDROGEL; IMPLANT; NONHUMAN; PERITONEUM LAVAGE; PRIORITY JOURNAL; PROTEIN STRUCTURE; RAT; STRESS STRAIN RELATIONSHIP; SYNTHESIS; VISCOELASTICITY; WATER CONTENT;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BIOMIMETIC MATERIALS; CROSS-LINKING REAGENTS; ELASTIN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLOW CYTOMETRY; FOREIGN-BODY REACTION; GLUTARAL; HYDROGELS; MATERIALS TESTING; MECHANICAL PROCESSES; MICE; MOLECULAR SEQUENCE DATA; PEPTIDES; PROSTHESIS IMPLANTATION; RHEOLOGY; STAINING AND LABELING; VISCOELASTIC SUBSTANCES;

EID: 55249122886     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2008.09.040     Document Type: Article

References (72)

1. Petka W.A., Harden J.L., McGrath K.P., Wirtz D., and Tirrell D.A. Reversible hydrogels from self-assembling artificial proteins. Science 281 (1998) 389-392
2. Rodríguez-Cabello J.C., Reguera J., Girotti A., Arias F.J., and Alonso M. Genetic engineering of protein-based polymers: the example of elastinlike polymers. Adv Polym Sci 200 (2006) 119-167
3. Wright E.R., and Conticello V.P. Self-assembly of block copolymers derived from elastin-mimetic polypeptide sequences. Adv Drug Deliv Rev 54 (2002) 1057-1073
4. Nagapudi K., Brinkman W.T., Thomas B.S., Park J.O., Srinivasarao M., Wright E., et al. Viscoelastic and mechanical behavior of recombinant protein elastomers. Biomaterials 26 23 (2005) 4695-4706
5. Wright E.R., McMillan R.A., Cooper A., Apkarian R.P., and Conticello V.P. Thermoplastic elastomer hydrogels via self-assembly of an elastin-mimetic triblock polypeptide. Adv Funct Mater 12 2 (2002) 1-6
6. Sallach R.E., Wei M., Biswas N., Conticello V.P., Lecommandoux S., Dluhy R.A., et al. Micelle density regulated by a reversible switch of protein secondary structure. J Am Chem Soc 128 36 (2006) 12014-12019
7. Nagapudi K., Brinkman W.T., Thomas B.S., Wright E.R., Conticello V.P., and Chaikof E.L. Protein-based thermoplastic elastomers. Macromolecules 38 (2005) 345-354
8. Wu X., Sallach R., Haller C.A., Caves J.A., Nagapudi K., Conticello V.P., et al. Alterations in physical cross-linking modulate mechanical properties of two-phase protein polymer networks. Biomacromolecules 6 6 (2005) 3037-3044
9. Bellingham C.M., Lillie M.A., Gosline J.M., Wright G.M., Starcher B.C., Bailey A.J., et al. Recombinant human elastin polypeptides self-assemble into biomaterials with elastin-like properties. Biopolymers 70 4 (2003) 445-455
10. Welsh E.R., and Tirrell D.A. Engineering the extracellular matrix: a novel approach to polymeric biomaterials. I. Control of the physical properties of artificial protein matrices designed to support adhesion of vascular endothelial cells. Biomacromolecules 1 1 (2000) 23-30
11. Urry D.W., and Parker T.M. Mechanics of elastin: molecular mechanism of biological elasticity and its relationship to contraction. J Muscle Res Cell Motil 23 5-6 (2002) 543-559
12. Vrhovski B., and Weiss A.S. Biochemistry of tropoelastin. Eur J Biochem 258 1 (1998) 1-18
13. Vieth S., Bellingham C.M., Keeley F.W., Hodge S.M., and Rousseau D. Microstructural and tensile properties of elastin-based polypeptides crosslinked with genipin and pyrroloquinoline quinone. Biopolymers 85 3 (2007) 199-206
14. Girotti A., Reguera J., Rodriguez-Cabello J.C., Arias F.J., Alonso M., and Matestera A. Design and bioproduction of a recombinant multi(bio)functional elastin-like protein polymer containing cell adhesion sequences for tissue engineering purposes. J Mater Sci Mater Med 15 4 (2004) 479-484
15. Martino M., and Tamburro A.M. Chemical synthesis of cross-linked poly(KGGVG). An elastin-like biopolymer. Biopolymers 59 1 (2001) 29-37
16. Lee J., Macoscko C.W., and Urry D.W. Elastomeric polypentapeptides cross-linked into matrixes and fibers. Biomacromolecules 2 (2001) 170-179
17. Nowatzki P.J., and Tirrell D.A. Physical properties of artificial extracellular matrix protein films prepared by isocyanate crosslinking. Biomaterials 25 (2004) 1261-1267
18. Trabbic-Carlson K., Setton L.A., and Chilkoti A. Swelling and mechanical behaviors of chemically cross-linked hydrogels of elastin-like polypeptides. Biomacromolecules 4 (2003) 572-580
19. McMillan R.A., Lee T.A.T., and Conticello V.P. Rapid assembly of synthetic genes encoding protein polymers. Macromolecules 32 (1999) 3643-3648
20. McMillan R.A., and Conticello V.P. Synthesis and characterization of elastin-mimetic protein gels derived from a well-defined polypeptide precursor. Macromolecules 33 (2000) 4809-4821
21. Zio K.D., and Tirrell D.A. Mechanical properties of artificial protein matrices engineered for control of cell and tissue behavior. Macromolecules 36 (2003) 1553-1558
22. Lim D.W., Nettles D.L., Setton L.A., and Chilkoti A. In situ cross-linking of elastin-like polypeptide block copolymers for tissue repair. Biomacromolecules 9 1 (2008) 222-230
23. Lim D.W., Nettles D.L., Setton L.A., and Chilkoti A. Rapid cross-linking of elastin-like polypeptides with (hydroxymethyl) phosphines in aqueous solution. Biomacromolecules 8 5 (2007) 1463-1470
24. McHale M.K., Setton L.A., and Chilkoti A. Synthesis and in vitro evaluation of enzymatically cross-linked elastin-like polypeptide gels for cartilaginous tissue repair. Tissue Eng 11 11-12 (2005) 1768-1779
25. Nagapudi K., Huang L., McMillan R.A., Brinkman W., Conticello V.P., and Chaikof E.L. Photomediated solid-state crosslinking of an elastin-mimetic recombinant protein polymer. Macromolecules 35 (2002) 1730-1737
26. Narayanan A.S., Page R.C., Kuzan F., and Cooper C.G. Elastin cross-linking in vitro. Studies on factors influencing the formation of desmosines by lysyl oxidase action on tropoelastin. Biochem J 173 3 (1978) 857-862
27. Bressan G.M., Pasquali-Ronchetti I., Fornieri C., Mattioli F., Castellani I., and Volpin D. Relevance of aggregation properties of tropoelastin to the assembly and structure of elastic fibers. J Ultrastruct Mol Struct Res 94 3 (1986) 209-216
28. Heilshorn S.C., DiZio K.A., Welsh E.R., and Tirrell D.A. Endothelial cell adhesion to the fibronectin CS5 domain in artificial extracellular matrix proteins. Biomaterials 24 23 (2003) 4245-4252
29. Meyer D.E., and Chilkoti A. Genetically encoded synthesis of protein-based polymers with precisely specified molecular weight and sequence by recursive directional ligation: examples from the elastin-like polypeptide system. Biomacromolecules 3 2 (2002) 357-367
30. Dinerman A.A., Cappello J., Ghandehari H., and Hoag S.W. Swelling behavior of a genetically engineered silk-elastinlike protein polymer hydrogel. Biomaterials 23 21 (2002) 4203-4210
31. Safley S.A., Kapp L.M., Tucker-Burden C., Hering B., Kapp J.A., and Weber C.J. Inhibition of cellular immune responses to encapsulated porcine islet xenografts by simultaneous blockade of two different costimulatory pathways. Transplantation 79 4 (2005) 409-418
32. van Hest J.C., and Tirrell D.A. Protein-based materials, toward a new level of structural control. Chem Commun 19 (2001) 1897-1904
33. Chang D.K., and Urry D.W. Molecular dynamics calculations on relaxed and extended states of the polypentapeptide of elastin. Chem Phys Lett 147 4 (1988) 395-400
34. Urry D.W., Gowda D.C., Parker T.M., Luan C.H., Reid M.C., Harris C.M., et al. Hydrophobicity scale for proteins based on inverse transition temperature. Biopolymers 32 (1992) 1243-1250
35. Urry D.W., Luan C.H., Parker T.M., Gowda D.C., Prasad K.U., Reid M.C., et al. Temperature of polypeptide inverse temperature transition depends on mean residue hydrophobicity. J Am Chem Soc 113 (1991) 4346-4348
36. Wood S.A., Lemons J.E., Prasad K.U., and Urry D.W. In vitro calcification and in vivo biocompatibility of the crosslinked polypentapeptide of elastin. J Biomed Mater Res 20 3 (1986) 315-335
37. Bellingham C.M., Woodhouse K.A., Robson P., Rothstein S.J., and Keeley F.W. Self-aggregation characteristics of recombinantly expressed human elastin polypeptides. Biochim Biophys Acta 1550 1 (2001) 6-19
38. Rosenbloom J., Abrams W.R., and Mecham R. Extracellular matrix 4: the elastic fiber. FASEB J 7 (1993) 1208-1218
39. Cox B.A., Starcher B.C., and Urry D.W. Communication: coacervation of tropoelastin results in fiber formation. J Biol Chem 249 3 (1974) 997-998
40. Wu W.J., Vrhovski B., and Weiss A.S. Glycosaminoglycans mediate the coacervation of human tropoelastin through dominant charge interactions involving lysine side chains. J Biol Chem 274 31 (1999) 21719-21724
41. Tobias J.W., Shrader T.E., Rocap G., and Varshavsky A. The N-end rule in bacteria. Science 254 (1991) 1324-1377
42. Panitch A., Yamaoka T., Fournier M.J., Mason T.L., and Tirrell D.A. Design and biosynthesis of elastin-like artificial extracellular matrix proteins containing periodically spaced fibronectin CS5 domains. Macromolecules 32 (1999) 1701-1703
43. Chang Y., Tsai C.C., Liang H.C., and Sung H.W. In vivo evaluation of cellular and acellular bovine pericardia fixed with a naturally occurring crosslinking agent (genipin). Biomaterials 23 12 (2002) 2447-2457
44. Jayakrishnan A., and Jameela S.R. Glutaraldehyde as a fixative in bioprostheses and drug delivery matrices. Biomaterials 17 5 (1996) 471-484
45. Gosline J.M., and French C.J. Dynamic mechanical properties of elastin. Biopolymers 18 8 (1979) 2091-2103
46. Humphrey J.D. Cardiovascular solid mechanics (2002), Springer, New York
47. Sacks M.S. Biaxial mechanical evaluation of planar biological materials. J Elast 61 (2000) 199-246
48. Carew E.O., Garg A., Barber J.E., and Vesely I. Stress relaxation preconditioning of porcine aortic valves. Ann Biomed Eng 32 4 (2004) 563-572
49. Carew E.O., Barber J.E., and Vesely I. Role of preconditioning and recovery time in repeated testing of aortic valve tissues: validation through quasilinear viscoelastic theory. Ann Biomed Eng 28 9 (2000) 1093-1100
50. Urry D.W., and Parker T.M. Biocompatibility of the bioelastic materials, poly(GVGVP) and its gamma-irradiation cross-linked matrix: summary of generic biological test results. J Bioact Compat Polym 6 (1991) 263-282
51. Rincon A.C., Molina-Martinez I.T., de Las Heras B., Alonso M., Bailez C., Rodriguez-Cabello J.C., et al. Biocompatibility of elastin-like polymer poly(VPAVG) microparticles: in vitro and in vivo studies. J Biomed Mater Res A 78 2 (2006) 343-351
52. Hoban L.D., Pierce M., Quance J., Hayward I., McKee A., Gowda D.C., et al. Use of polypentapeptides of elastin to prevent postoperative adhesions: efficacy in a contaminated peritoneal model. J Surg Res 56 2 (1994) 179-183
53. Wei S.M., Katona E., Fachet J., Fulop Jr. T., Robert L., and Jacob M.P. Epitope specificity of monoclonal and polyclonal antibodies to human elastin. Int Arch Allergy Immunol 115 1 (1998) 33-41
54. Jordan S.W., Haller C.A., Sallach R.E., Apkarian R.P., Hanson S.R., and Chaikof E.L. The effect of a recombinant elastin-mimetic coating of an ePTFE prosthesis on acute thrombogenicity in a baboon arteriovenous shunt. Biomaterials 28 6 (2007) 1191-1197
55. Woodhouse K.A., Klement P., Chen V., Gorbet M.B., Keeley F.W., Stahl R., et al. Investigation of recombinant human elastin polypeptides as non-thrombogenic coatings. Biomaterials 25 19 (2004) 4543-4553
56. Meyer D.E., Kong G.A., Dewhirst M.W., Zalutsky M.R., and Chilkoti A. Targeting a genetically engineered elastin-like polypeptide to solid tumors by local hypothermia. Cancer Res 61 (2001) 1548-1554
57. Liu W., Dreher M.R., Chow D.C., Zalutsky M.R., and Chilkoti A. Tracking the in vivo fate of recombinant polypeptides by isotopic labeling. J Controlled Release 114 (2006) 184-192
58. Betre H., Liu W., Zalutsky M.R., Chilkoti A., Kraus V.B., and Setton L.A. A thermally responsive biopolymer for intra-articular drug delivery. J Controlled Release 115 2 (2006) 175-182
59. Mithieux S.M., Rasko J.E.J., and Weiss A.S. Synthetic elastin hydrogels derived from massive elastic assemblies of self-organized human protein monomers. Biomaterials 25 (2004) 4921-4927
60. Cappello J., Crissman J.W., Crissman M., Ferrari F.A., Textor G., Wallis O., et al. In-situ self-assembling protein polymer gel systems for administration, delivery, and release of drugs. J Control Release 53 1-3 (1998) 105-117
61. Hatefi A., Cappello J., and Ghandehari H. Adenoviral gene delivery to solid tumors by recombinant silk-elastinlike protein polymers. Pharm Res 24 4 (2007) 773-779
62. Megeed Z., Haider M., Li D., O'Malley Jr. B.W., Cappello J., and Ghandehari H. In vitro and in vivo evaluation of recombinant silk-elastinlike hydrogels for cancer gene therapy. J Control Release 94 2-3 (2004) 433-445
63. Anderson J.M. In vivo biocompatibility of implantable delivery systems and biomaterials. Eur J Pharm Biopharm 40 (1994) 1-8
64. Hunt J.A., Vince D.G., and Williams D.F. Image analysis in the evaluation of biomaterials. J Biomed Eng 15 (1993) 39-45
65. Andersson M., Suska F., Johansson A., Berglin M., Emanuelsson L., Elwing H., et al. Effect of molecular mobility of polymeric implants on soft tissue reactions: an in vivo study in rats. J Biomed Mater Res A 84 3 (2008) 652-660
66. Butler K., Benghuzzui H., Tucci M., and Cason Z. A comparison of fibrous tissue formation surrounding intraperitoneal and subcutaneous implantation of ALCAP, HA, and TCP ceramic devices. Biomed Sci Instrum 34 (1997) 18-23
67. Shin H., Quinten Ruhe P., Mikos A.G., and Jansen J.A. In vivo bone and soft tissue response to injectable, biodegradable oligo(poly(ethylene glycol) fumarate) hydrogels. Biomaterials 24 19 (2003) 3201-3211
68. Giavaresi G., Torricelli P., Fornasari P.M., Giardino R., Barbucci R., and Leone G. Blood vessel formation after soft-tissue implantation of hyaluronan-based hydrogel supplemented with copper ions. Biomaterials 26 16 (2005) 3001-3008
69. Barbosa J.N., Madureira P., Barbosa M.A., and Aguas A.P. The influence of functional groups of self-assembled monolayers on fibrous capsule formation and cell recruitment. J Biomed Mater Res A 76 4 (2006) 737-743
70. Nair A., Zou L., Bhattacharyya D., Timmons R.B., and Tang L. Species and density of implant surface chemistry affect the extent of foreign body reactions. Langmuir 24 5 (2008) 2015-2024
71. Voskerician G., Gingras P.H., and Anderson J.M. Macroporous condensed poly(tetrafluoroethylene). I. In vivo inflammatory response and healing characteristics. J Biomed Mater Res A 76 2 (2006) 234-242
72. Wu X., Sallach R.E., Caves J.M., Conticello V.P., and Chaikof E.L. Deformation responses of a physically cross-linked high molecular weight elastin-like protein polymer. Biomacromolecules 9 (2008) 1787-1794