Hydrogels of collagen-inspired telechelic triblock copolymers for the sustained release of proteins

Journal of Controlled Release

Volumn 147, Issue 2, 2010, Pages 298-303

  Teles, H ^a   Vermonden, T ^b   Eggink, G ^a   Hennink, W E ^b   de Wolf, F A ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Biomedical materials; Drug delivery; Hydrogels; Physical cross linking; Thermoresponsive

Indexed keywords

ABA TRIBLOCK COPOLYMER; BIOMEDICAL MATERIAL; DENSE NETWORK; DRUG DELIVERY SYSTEM; ELASTIC PROPERTIES; ENCAPSULATED PROTEINS; HETEROLOGOUS PROTEINS; MESH SIZE; PHYSICAL CROSS-LINKING; POLYMER CONCENTRATIONS; POLYMER LENGTH; PROTEIN DIFFUSION; RECOMBINANT YEAST; SURFACE EROSION; SUSTAINED RELEASE; TELECHELICS; THERMO SENSITIVE; THERMO-RESPONSIVE; TRIBLOCK COPOLYMERS;

BIOMEDICAL ENGINEERING; BLOCK COPOLYMERS; COLLAGEN; COPOLYMERIZATION; DRUG DELIVERY; EROSION; GELS; POLYMERS; SWELLING;

HYDROGELS;

BOVINE SERUM ALBUMIN; COLLAGEN; COPOLYMER;

ARTICLE; DRUG DELIVERY SYSTEM; DRUG RELEASE; HYDROGEL; PRIORITY JOURNAL; SUSTAINED DRUG RELEASE; TEMPERATURE; YEAST;

COLLAGEN; DELAYED-ACTION PREPARATIONS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; HYDROGELS; OLIGOPEPTIDES; PICHIA; POLYMERS; PROLINE; RECOMBINANT PROTEINS; RHEOLOGY; SERUM ALBUMIN, BOVINE; SOLUBILITY; VISCOSITY;

EID: 77957021085     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.07.098     Document Type: Article

References (26)

1. Van Tomme S.R., Storm G., Hennink W.E. In situ gelling hydrogels for pharmaceutical and biomedical applications. Int. J. Pharm. 2008, 355:1-18.
2. Ramachandran S., Yu Y.B. Peptide-based viscoelastic matrices for drug delivery and tissue repair. BioDrugs 2006, 20:263-269.
3. Peppas N.A., Bures P., Leobandung W., Ichikawa H. Hydrogels in pharmaceutical formulations. Eur. J. Pharm. Biopharm. 2000, 50:27-46.
4. Gupta P., Vermani K., Garg S. Hydrogels: from controlled release to pH-responsive drug delivery. Drug Discov. Today 2002, 7:569-579.
5. Hennink W.E., van Nostrum C.F. Novel crosslinking methods to design hydrogels. Adv. Drug Deliv. Rev. 2002, 54:13-36.
6. Deming T.J. Polypeptide hydrogels via a unique assembly mechanism. Soft Matter 2005, 1:28-35.
7. Olsen D., Yang C., Bodo M., Chang R., Leigh S., Baez J., Carmichael D., Perala M., Hamalainen E.R., Jarvinen M., Polarek J. Recombinant collagen and gelatin for drug delivery. Adv. Drug Deliv. Rev. 2003, 55:1547-1567.
8. Yang C., Hillas P.J., Baez J.A., Nokelainen M., Balan J., Tang J., Spiro R., Polarek J.W. The application of recombinant human collagen in tissue engineering. BioDrugs 2004, 18:103-119.
9. Young S., Wong M., Tabata Y., Mikos A.G. Gelatin as a delivery vehicle for the controlled release of bioactive molecules. J. Control. Release 2005, 109:256-274.
10. Djabourov M. Progress in Biotechnology-Industrial Proteins in Perspective 2003, 133-218. Elsevier Science, Amsterdam.
11. Dinerman A.A., Cappello J., Ghandehari H., Hoag S.W. Swelling behavior of a genetically engineered silk-elastinlike protein polymer hydrogel. Biomaterials 2002, 23:4203-4210.
12. Baez J., Olsen D., Polarek J.W. Recombinant microbial systems for the production of human collagen and gelatin. Appl. Microbiol. Biotechnol. 2005, 69:245-252.
13. Werten M.W.T., van den Bosch T.J., Wind R.D., Mooibroek H., de Wolf F.A. High-yield secretion of recombinant gelatins by Pichia pastoris. Yeast 1999, 15:1087-1096.
14. Werten M.W.T., Wisselink W.H., Jansen-van den Bosch T.J., de Bruin E.C., de Wolf F.A. Secreted production of a custom-designed, highly hydrophilic gelatin in Pichia pastoris. Protein Eng. 2001, 14:447-454.
15. Olsen D., Jiang J., Chang R., Duffy R., Sakaguchi M., Leigh S., Lundgard R., Ju J., Buschman F., Truong-Le V., Pham B., Polarek J.W. Expression and characterization of a low molecular weight recombinant human gelatin: development of a substitute for animal-derived gelatin with superior features. Protein Expr. Purif. 2005, 40:346-357.
16. Werten M.W.T., Teles H., Moers A.P.H.A., Wolbert E.J.H., Sprakel J., Eggink G., de Wolf F.A. Precision gels from collagen-inspired triblock copolymers. Biomacromolecules 2009, 10:1106-1113.
17. Skrzeszewska P.J., de Wolf F.A., Werten M.W.T., Moers A.P.H.A., Cohen Stuart M.A., van der Gucht J. Physical gels of telechelic triblock copolymers with precisely defined junction multiplicity. Soft Matter 2009, 5:2057-2062.
18. Teles H., Skrzeszewska P.J., Werten M.W.T., van der Gucht J., Eggink G., de Wolf F.A. Influence of molecular size on gel-forming properties of telechelic collagen-inspired polymers. Soft Matter 2010, in press, doi:10.1039/C1030SM00175A.
19. http://www.ncbi.nlm.nih.gov/genbank.
20. Goodwin J.W., Hughes R.W. Rheology for Chemists: An introduction 2000, Royal Society of Chemistry, Cambridge.
21. Merrill E.W., Dennison K.A., Sung C. Partitioning and diffusion of solutes in hydrogels of poly(ethylene oxide). Biomaterials 1993, 14:1117-1126.
22. Stenekes R.J., De Smedt S.C., Demeester J., Sun G., Zhang Z., Hennink W.E. Pore sizes in hydrated dextran microspheres. Biomacromolecules 2000, 1:696-703.
23. Ritger P.L., Peppas N.A. A simple equation for description of solute release II. Fickian and anomalous release from swellable devices. J. Control. Release 1987, 5:37-42.
24. van de Manakker F., Braeckmans K., el Morabit N., De Smedt S.C., van Nostrum C.F., Hennink W.E. Protein release behaviour of self-assembled PEG-β-cyclodextrin/PEG-cholesterol hydrogels. Adv. Funct. Mater. 2009, 19:2992-3001.
25. Ritger P.L., Peppas N.A. A simple equation for description of solute release I. Fickian and non-Fickian release from non-swellabe devices in the form of slabs, spheres, cylinders or discs. J. Control. Release 1987, 5:23-36.
26. Skrzeszewska P.J., Sprakel J., De Wolf F.A., Fokkink R., Cohen Stuart M.A., van der Gucht J. Fracture and self-healing in a well-defined self-assembled polymer network. Macromolecules 2010, 43:3542-3548.