CpG Island Hypermethylation at Multiple Gene Sites in Diagnosis and Prognosis of Prostate Cancer

Urology

Volumn 71, Issue 1, 2008, Pages 161-167

  Ellinger, Jörg ^a   Bastian, Patrick J ^a   Jurgan, Thomas ^a   Biermann, Katharina ^a   Kahl, Philip ^a   Heukamp, Lukas C ^a   Wernert, Nicolas ^a   Müller, Stefan C ^a   von Ruecker, Alexander ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PROSTATE SPECIFIC ANTIGEN;

ADULT; AGED; ANNEXIN2 GENE; APC GENE; ARTICLE; CANCER DIAGNOSIS; CANCER RECURRENCE; CANCER STAGING; CARCINOGENESIS; CPG ISLAND; DNA METHYLATION; EDNRB GENE; GENE; GENE LOCUS; GENE SILENCING; GLEASON SCORE; GSTP1 GENE; HUMAN; MAJOR CLINICAL STUDY; MALE; MDR1 GENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; PROSTATE CANCER; PROSTATE HYPERTROPHY; PROSTATECTOMY; PTGS2 GENE; RARBETA GENE; REPRIMO GENE; SENSITIVITY AND SPECIFICITY; TIG1 GENE;

AGED; ANNEXIN A2; CELL CYCLE PROTEINS; CPG ISLANDS; CYCLOOXYGENASE 2; DNA METHYLATION; GENE SILENCING; GLUTATHIONE S-TRANSFERASE PI; GLYCOPROTEINS; HUMANS; LYMPHATIC METASTASIS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; NEOPLASM INVASIVENESS; P-GLYCOPROTEIN; POLYMERASE CHAIN REACTION; PROGNOSIS; PROSTATIC HYPERPLASIA; PROSTATIC NEOPLASMS; SEMINAL VESICLES; SENSITIVITY AND SPECIFICITY;

EID: 38649101553     PISSN: 00904295     EISSN: 15279995     Source Type: Journal    
DOI: 10.1016/j.urology.2007.09.056     Document Type: Article

References (24)

1. Jemal A., Siegel R., Ward E., et al. Cancer statistics, 2007. CA Cancer J Clin 57 (2007) 43-66
2. Draisma G., Boer R., Otto S.J., et al. Lead times and overdetection due to prostate-specific antigen screening: estimates from the European Randomized Study of Screening for Prostate Cancer. J Natl Cancer Inst 95 (2003) 868-878
3. Enokida H., Shiina H., Urakami S., et al. Multigene methylation analysis for detection and staging of prostate cancer. Clin Cancer Res 11 (2005) 6582-6588
4. Yegnasubramanian S., Kowalski J., Gonzalgo M.L., et al. Hypermethylation of CpG islands in primary and metastatic human prostate cancer. Cancer Res 64 (2004) 1975-1986
5. Woodson K., Gillespie J., Hanson J., et al. Heterogeneous gene methylation patterns among pre-invasive and cancerous lesions of the prostate: a histopathologic study of whole mount prostate specimens. Prostate 60 (2004) 25-31
6. Bastian P.J., Ellinger J., Wellmann A., et al. Diagnostic and prognostic information in prostate cancer with the help of a small set of hypermethylated gene loci. Clin Cancer Res 11 (2005) 4097-4106
7. Tokumaru Y., Harden S.V., Sun D.I., et al. Optimal use of a panel of methylation markers with GSTP1 hypermethylation in the diagnosis of prostate adenocarcinoma. Clin Cancer Res 10 (2004) 5518-5522
8. Kang G.H., Lee S., Lee H.J., et al. Aberrant CpG island hypermethylation of multiple genes in prostate cancer and prostatic intraepithelial neoplasia. J Pathol 202 (2004) 233-240
9. Woodson K., Hanson J., and Tangrea J. A survey of gene-specific methylation in human prostate cancer among black and white men. Cancer Lett 205 (2004) 181-188
10. Liu J.W., Shen J.J., Tanzillo-Swarts A., et al. Annexin II expression is reduced or lost in prostate cancer cells and its re-expression inhibits prostate cancer cell migration. Oncogene 22 (2003) 1475-1485
11. Enokida H., Shiina H., Igawa M., et al. CpG hypermethylation of MDR1 gene contributes to the pathogenesis and progression of human prostate cancer. Cancer Res 64 (2004) 5956-5962
12. Jeronimo C., Henrique R., Hoque M.O., et al. Quantitative RARbeta2 hypermethylation: a promising prostate cancer marker. Clin Cancer Res 10 (2004) 4010-4014
13. Takahashi T., Suzuki M., Shigematsu H., et al. Aberrant methylation of Reprimo in human malignancies. Int J Cancer 115 (2005) 503-510
14. Bastian P.J., Ellinger J., Heukamp L.C., et al. Prognostic value of CpG island hypermethylation at PTGS2, RAR-beta, EDNRB, and other gene loci in patients undergoing radical prostatectomy. Eur Urol 51 (2007) 665-674
15. Lehmann U., Langer F., Feist H., et al. Quantitative assessment of promoter hypermethylation during breast cancer development. Am J Pathol 160 (2002) 605-612
16. Pao M.M., Tsutsumi M., Liang G., et al. The endothelin receptor B (EDNRB) promoter displays heterogeneous, site specific methylation patterns in normal and tumor cells. Hum Mol Genet 10 (2001) 903-910
17. Suzuki M., Shigematsu H., Shivapurkar N., et al. Methylation of apoptosis related genes in the pathogenesis and prognosis of prostate cancer. Cancer Lett 242 (2006) 222-230
18. Winkler M.H., Livni N., Mannion E.M., et al. Characteristics of incidental prostatic adenocarcinoma in contemporary radical cystoprostatectomy specimens. BJU Int 99 (2007) 554-558
19. Florl A.R., Steinhoff C., Muller M., et al. Coordinate hypermethylation at specific genes in prostate carcinoma precedes LINE-1 hypomethylation. Br J Cancer 91 (2004) 985-994
20. Jeronimo C., Henrique R., Campos P.F., et al. Endothelin B receptor gene hypermethylation in prostate adenocarcinoma. J Clin Pathol 56 (2003) 52-55
21. Singal R., Ferdinand L., Reis I.M., et al. Methylation of multiple genes in prostate cancer and the relationship with clinicopathological features of disease. Oncol Rep 12 (2004) 631-637
22. Enokida H., Shiina H., Urakami S., et al. Ethnic group-related differences in CpG hypermethylation of the GSTP1 gene promoter among African-American, Caucasian and Asian patients with prostate cancer. Int J Cancer 116 (2005) 174-181
23. Enokida H., Shiina H., Urakami S., et al. Smoking influences aberrant CpG hypermethylation of multiple genes in human prostate carcinoma. Cancer 106 (2006) 79-86
24. Kwabi-Addo B., Chung W., Shen L., et al. Age-related DNA methylation changes in normal human prostate tissues. Clin Cancer Res 13 (2007) 3796-3802