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Volumn 983, Issue , 2003, Pages 28-42

Hypomethylation: One side of a larger picture

Author keywords

5 Methylcytosine; Cancer; Hypermethylation; Hypomethylation; Repetitive sequences; Transposable elements

Indexed keywords

5 METHYLCYTOSINE; MICROSATELLITE DNA;

EID: 0037355911     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2003.tb05960.x     Document Type: Conference Paper
Times cited : (138)

References (127)
  • 1
    • 0030459140 scopus 로고    scopus 로고
    • The role of DNA methylation in cancer genetic and epigenetics
    • LAIRD, P.W. & R. JAENISCH. 1996. The role of DNA methylation in cancer genetic and epigenetics. Annu. Rev. Genet. 30: 441-464.
    • (1996) Annu. Rev. Genet. , vol.30 , pp. 441-464
    • Laird, P.W.1    Jaenisch, R.2
  • 2
    • 0035799382 scopus 로고    scopus 로고
    • Changes in DNA methylation in neoplasia: Pathophysiology and therapeutic implications
    • SANTINI, V., H.M. KANTARJIAN & J.P. ISSA. 2001. Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications. Ann. Intern. Med. 134(7): 573-586.
    • (2001) Ann. Intern. Med. , vol.134 , Issue.7 , pp. 573-586
    • Santini, V.1    Kantarjian, H.M.2    Issa, J.P.3
  • 3
    • 18244388241 scopus 로고    scopus 로고
    • DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis
    • ESTELLER, M., M.F. FRAGA, M. Guo, et al. 2001. DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis. Hum. Mol. Genet. 10(26): 3001-3007.
    • (2001) Hum. Mol. Genet. , vol.10 , Issue.26 , pp. 3001-3007
    • Esteller, M.1    Fraga, M.F.2    Guo, M.3
  • 4
    • 0036145156 scopus 로고    scopus 로고
    • Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours
    • ESTELLER, M. & J.G. HERMAN. 2002. Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours. J. Pathol. 196(1): 1-7.
    • (2002) J. Pathol. , vol.196 , Issue.1 , pp. 1-7
    • Esteller, M.1    Herman, J.G.2
  • 5
    • 0034305821 scopus 로고    scopus 로고
    • DNA methylation in health and disease
    • ROBERTSON, K.D. & A.P. WOLFFE. 2000. DNA methylation in health and disease. Nat. Rev. Genet. 1(1): 11-19.
    • (2000) Nat. Rev. Genet. , vol.1 , Issue.1 , pp. 11-19
    • Robertson, K.D.1    Wolffe, A.P.2
  • 6
    • 0036352687 scopus 로고    scopus 로고
    • Global and gene-specific methylation patterns in cancer: Aspects of tumor biology and clinical potential
    • FRUHWALD, M.C. & C. PLASS. 2002. Global and gene-specific methylation patterns in cancer: aspects of tumor biology and clinical potential. Mol. Genet. Metab. 75(1): 1-16.
    • (2002) Mol. Genet. Metab. , vol.75 , Issue.1 , pp. 1-16
    • Fruhwald, M.C.1    Plass, C.2
  • 7
    • 0022540321 scopus 로고
    • CpG-rich islands and the function of DNA methylation
    • BIRD, A.P. 1986. CpG-rich islands and the function of DNA methylation. Nature 321(6067): 209-213.
    • (1986) Nature , vol.321 , Issue.6067 , pp. 209-213
    • Bird, A.P.1
  • 8
    • 0020489781 scopus 로고
    • Amount and distribution of 5-Methylcytosine in human DNA from different types of tissues of cells
    • EHRLICH, M., M.A. GAMA-SOSA, L.H. HUANG, et al. 1982. Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells. Nucleic Acids Res. 10(8): 2709-2721.
    • (1982) Nucleic Acids Res. , vol.10 , Issue.8 , pp. 2709-2721
    • Ehrlich, M.1    Gama-Sosa, M.A.2    Huang, L.H.3
  • 9
    • 0033579311 scopus 로고    scopus 로고
    • DNA methylation de novo
    • BIRD, A. 1999. DNA methylation de novo. Science 286(5448): 2287-2288.
    • (1999) Science , vol.286 , Issue.5448 , pp. 2287-2288
    • Bird, A.1
  • 10
    • 0033933366 scopus 로고    scopus 로고
    • DNA hypomethylation and unusual chromosome instability in cell lines from ICF syndrome patients
    • TUCK-MULLER, C.M., A. NARAYAN, F. TSIEN, et al. 2000. DNA hypomethylation and unusual chromosome instability in cell lines from ICF syndrome patients. Cytogenet. Cell Genet. 89(1-2): 121-128.
    • (2000) Cytogenet. Cell Genet. , vol.89 , Issue.1-2 , pp. 121-128
    • Tuck-Muller, C.M.1    Narayan, A.2    Tsien, F.3
  • 11
    • 0034092009 scopus 로고    scopus 로고
    • DNA methylation: Past, present and future directions
    • ROBERTSON, K.D. & P.A. JONES. 2000. DNA methylation: past, present and future directions. Carcinogenesis 21(3): 461-467.
    • (2000) Carcinogenesis , vol.21 , Issue.3 , pp. 461-467
    • Robertson, K.D.1    Jones, P.A.2
  • 12
    • 0020851370 scopus 로고
    • DNA modification, differentiation, and transformation
    • JONES, P.A., S.M. TAYLOR & V. WILSON. 1983. DNA modification, differentiation, and transformation. J. Exp. Zool. 228(2): 287-295.
    • (1983) J. Exp. Zool. , vol.228 , Issue.2 , pp. 287-295
    • Jones, P.A.1    Taylor, S.M.2    Wilson, V.3
  • 13
    • 0024153586 scopus 로고
    • Hypomethylation of DNA in the regulation of gene expression
    • CHANDLER, L.A. & P.A. JONES. 1988. Hypomethylation of DNA in the regulation of gene expression. Dev. Biol. (N Y 1985) 5: 335-349.
    • (1988) Dev. Biol. (N Y 1985) , vol.5 , pp. 335-349
    • Chandler, L.A.1    Jones, P.A.2
  • 14
    • 0018400334 scopus 로고
    • Distribution pattern and enzymic hypermethylation of inverted repetitive DNA sequences in P815 mastocytoma cells
    • DRAHOVSKY, D., T.L. BOEHM & W. KREIS. 1979. Distribution pattern and enzymic hypermethylation of inverted repetitive DNA sequences in P815 mastocytoma cells. Biochim. Biophys. Acta 563(1): 28-35.
    • (1979) Biochim. Biophys. Acta , vol.563 , Issue.1 , pp. 28-35
    • Drahovsky, D.1    Boehm, T.L.2    Kreis, W.3
  • 15
    • 0019423126 scopus 로고
    • Methylation of reiterated sequences in mammalian DNAs. Effects of the tissue type, age, malignancy and hormonal induction
    • ROMANOV, G.A. & B.F. VANYUSHIN. 1981. Methylation of reiterated sequences in mammalian DNAs. Effects of the tissue type, age, malignancy and hormonal induction. Biochim. Biophys. Acta 653(2): 204-218.
    • (1981) Biochim. Biophys. Acta , vol.653 , Issue.2 , pp. 204-218
    • Romanov, G.A.1    Vanyushin, B.F.2
  • 16
    • 0019884371 scopus 로고
    • 5-Methylcytosine in eukaryotic DNA
    • EHRLICH, M. & R.Y. WANG. 1981. 5-Methylcytosine in eukaryotic DNA. Science 212(4501): 1350-1357.
    • (1981) Science , vol.212 , Issue.4501 , pp. 1350-1357
    • Ehrlich, M.1    Wang, R.Y.2
  • 17
    • 0021101229 scopus 로고
    • The 5-Methylcytosine content of DNA from human tumors
    • GAMA-SOSA, M.A., V.A. SLAGEL, R.W. TREWYN, et al. 1983. The 5-methylcytosine content of DNA from human tumors. Nucleic Acids Res: 11(19): 6883-6894.
    • (1983) Nucleic Acids Res. , vol.11 , Issue.19 , pp. 6883-6894
    • Gama-Sosa, M.A.1    Slagel, V.A.2    Trewyn, R.W.3
  • 18
    • 0022922305 scopus 로고
    • Decreased methylation of the major mouse long interspersed repeated DNA during aging and in myeloma cells
    • MAYS-HOOPES, L., W. CHAO, H.C. BUTCHER & R.C. HUANG. 1986. Decreased methylation of the major mouse long interspersed repeated DNA during aging and in myeloma cells. Dev. Genet. 7(2): 65-73.
    • (1986) Dev. Genet. , vol.7 , Issue.2 , pp. 65-73
    • Mays-Hoopes, L.1    Chao, W.2    Butcher, H.C.3    Huang, R.C.4
  • 19
    • 0025889061 scopus 로고
    • DNA methylation and cellular ageing
    • CATANIA, J. & D.S. FAIRWEATHER. 1991. DNA methylation and cellular ageing. Mutat. Res. 256(2-6): 283-293.
    • (1991) Mutat. Res. , vol.256 , Issue.2-6 , pp. 283-293
    • Catania, J.1    Fairweather, D.S.2
  • 20
    • 0027442560 scopus 로고
    • Undermethylation of specific LINE-1 sequences in human cells producing a LINE-1-encoded protein
    • THAYER, R.E., M.F. SINGER & T.G. FANNING. 1993. Undermethylation of specific LINE-1 sequences in human cells producing a LINE-1-encoded protein. Gene 133(2): 273-277.
    • (1993) Gene , vol.133 , Issue.2 , pp. 273-277
    • Thayer, R.E.1    Singer, M.F.2    Fanning, T.G.3
  • 21
    • 0034176798 scopus 로고    scopus 로고
    • DNA hypermethylation in tumorigenesis: Epigenetics joins genetics
    • BAYLIN, S.B. & J.G. HERMAN. 2000. DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet. 16(4):168-174.
    • (2000) Trends Genet. , vol.16 , Issue.4 , pp. 168-174
    • Baylin, S.B.1    Herman, J.G.2
  • 22
    • 0025006860 scopus 로고
    • High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines
    • ANTEQUERA, F., J. BOYES & A. BIRD. 1990. High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines. Cell. 62(3): 503-514.
    • (1990) Cell , vol.62 , Issue.3 , pp. 503-514
    • Antequera, F.1    Boyes, J.2    Bird, A.3
  • 23
    • 0024281345 scopus 로고
    • DNA methylation and gene activity
    • CEDAR, H. 1988. DNA methylation and gene activity. Cell 53(1): 3-4.
    • (1988) Cell , vol.53 , Issue.1 , pp. 3-4
    • Cedar, H.1
  • 24
    • 0028106737 scopus 로고
    • Dependence of transcriptional repression on CpG methylation density
    • HSIEH, C.L. 1994. Dependence of transcriptional repression on CpG methylation density. Mol. Cell Biol. 14(8): 5487-5494.
    • (1994) Mol. Cell Biol. , vol.14 , Issue.8 , pp. 5487-5494
    • Hsieh, C.L.1
  • 25
    • 0028304151 scopus 로고
    • The impact of 5′-CG-3′ methylation on the activity of different eukaryotic promoters: A comparative study
    • MUIZNIEKS, I. & W. DOERFLER. 1994. The impact of 5′-CG-3′ methylation on the activity of different eukaryotic promoters: a comparative study. FEBS Lett. 344(2-3): 251-254.
    • (1994) FEBS Lett. , vol.344 , Issue.2-3 , pp. 251-254
    • Muiznieks, I.1    Doerfler, W.2
  • 26
    • 0019318994 scopus 로고
    • DNA methylation and gene function
    • RAZIN, A. & A.D. RIGGS. 1980. DNA methylation and gene function. Science 210(4470): 604-610.
    • (1980) Science , vol.210 , Issue.4470 , pp. 604-610
    • Razin, A.1    Riggs, A.D.2
  • 27
    • 0018776724 scopus 로고
    • 5-Methylcytosine content of nuclear DNA during chemical hepatocarcinogenesis and in carcinomas which result
    • LAPEYRE, J.N. & F.F. BECKER. 1979. 5-Methylcytosine content of nuclear DNA during chemical hepatocarcinogenesis and in carcinomas which result. Biochem. Biophys. Res. Commun. 87(3): 698-705.
    • (1979) Biochem. Biophys. Res. Commun. , vol.87 , Issue.3 , pp. 698-705
    • Lapeyre, J.N.1    Becker, F.F.2
  • 29
    • 0020552634 scopus 로고
    • DNA hypomethylation in Morris hepatomas
    • Lu, L.J., E. RANDERATH & K. RANDERATH. 1983. DNA hypomethylation in Morris hepatomas. Cancer Lett. 19(2): 231-239.
    • (1983) Cancer Lett. , vol.19 , Issue.2 , pp. 231-239
    • Lu, L.J.1    Randerath, E.2    Randerath, K.3
  • 30
    • 0023899395 scopus 로고
    • Hypomethylation of DNA in estrogen-induced and -dependent hamster kidney tumors
    • Lu, L.J., J.G. LIEHR, D.A. SIRBASKU, et al. 1988. Hypomethylation of DNA in estrogen-induced and -dependent hamster kidney tumors. Carcinogenesis. 9(6): 925-929.
    • (1988) Carcinogenesis , vol.9 , Issue.6 , pp. 925-929
    • Lu, L.J.1    Liehr, J.G.2    Sirbasku, D.A.3
  • 31
    • 0034796736 scopus 로고    scopus 로고
    • Alteration of DNA methylation in gastrointestinal carcinogenesis
    • FANG, J.Y. & S.D. XIAO. 2001. Alteration of DNA methylation in gastrointestinal carcinogenesis. J. Gastroenterol. Hepatol. 16(9): 960-968.
    • (2001) J. Gastroenterol. Hepatol. , vol.16 , Issue.9 , pp. 960-968
    • Fang, J.Y.1    Xiao, S.D.2
  • 32
    • 0023848637 scopus 로고
    • Reduced genomic 5-Methylcytosine content in human colonic neoplasia
    • FEINBERG, A.P., C.W. GEHRKE, K.C. KUO & M. EHRLICH. 1988. Reduced genomic 5-methylcytosine content in human colonic neoplasia. Cancer Res. 48(5): 1159-1161.
    • (1988) Cancer Res. , vol.48 , Issue.5 , pp. 1159-1161
    • Feinberg, A.P.1    Gehrke, C.W.2    Kuo, K.C.3    Ehrlich, M.4
  • 33
    • 0020699979 scopus 로고
    • Hypomethylation distinguishes genes of some human cancers from their normal counterparts
    • FEINBERG, A.P. & B. VOGELSTEIN. 1983. Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 301(5895): 89-92.
    • (1983) Nature , vol.301 , Issue.5895 , pp. 89-92
    • Feinberg, A.P.1    Vogelstein, B.2
  • 34
    • 0021950948 scopus 로고
    • Hypomethylation of DNA from benign and malignant human colon neoplasms
    • GOELZ, S.E., B. VOGELSTEIN, S.R. HAMILTON & A.P. FEINBERG. 1985. Hypomethylation of DNA from benign and malignant human colon neoplasms. Science 228(4696): 187-190.
    • (1985) Science , vol.228 , Issue.4696 , pp. 187-190
    • Goelz, S.E.1    Vogelstein, B.2    Hamilton, S.R.3    Feinberg, A.P.4
  • 35
    • 0021139979 scopus 로고
    • Cell lineage-specific undermethylation of mouse repetitive DNA
    • CHAPMAN, V., L. FORRESTER, J. SANFORD, et al. 1984. Cell lineage-specific undermethylation of mouse repetitive DNA. Nature 307(5948): 284-286.
    • (1984) Nature , vol.307 , Issue.5948 , pp. 284-286
    • Chapman, V.1    Forrester, L.2    Sanford, J.3
  • 36
    • 0021771159 scopus 로고
    • Methylation patterns of repetitive DNA sequences in germ cells of Mus musculus
    • SANFORD, J., L. FORRESTER, V. CHAPMAN, et al. 1984. Methylation patterns of repetitive DNA sequences in germ cells of Mus musculus. Nucleic Acids Res. 12(6): 2823-2836.
    • (1984) Nucleic Acids Res. , vol.12 , Issue.6 , pp. 2823-2836
    • Sanford, J.1    Forrester, L.2    Chapman, V.3
  • 37
    • 0022423420 scopus 로고
    • Pattern of undermethylation of the major satellite DNA of mouse sperm
    • FEINSTEIN, S.I., V.R. RACANIELLO, M. EHRLICH, et al. 1985: Pattern of undermethylation of the major satellite DNA of mouse sperm. Nucleic Acids Res. 13(11): 3969-3978.
    • (1985) Nucleic Acids Res. , vol.13 , Issue.11 , pp. 3969-3978
    • Feinstein, S.I.1    Racaniello, V.R.2    Ehrlich, M.3
  • 38
    • 0001992028 scopus 로고    scopus 로고
    • Satellite DNA hypomethylation vs. overall genomic hypomethylation in ovarian epithelial tumors of different malignant potential
    • QU, G., L. DUBEAU, A. NARAYAN, et al. 1999. Satellite DNA hypomethylation vs. overall genomic hypomethylation in ovarian epithelial tumors of different malignant potential. Mutat. Res. 423(1-2): 91-101.
    • (1999) Mutat. Res. , vol.423 , Issue.1-2 , pp. 91-101
    • Qu, G.1    Dubeau, L.2    Narayan, A.3
  • 39
    • 0031816567 scopus 로고    scopus 로고
    • Hypomethylation of pericentromeric DNA in breast adenocarcinomas
    • NARAYAN, A., W. JI, X.Y. ZHANG, et al. 1998. Hypomethylation of pericentromeric DNA in breast adenocarcinomas. Int. J. Cancer 77(6): 833-838.
    • (1998) Int. J. Cancer , vol.77 , Issue.6 , pp. 833-838
    • Narayan, A.1    Ji, W.2    Zhang, X.Y.3
  • 40
    • 0033081639 scopus 로고    scopus 로고
    • Frequent hypomethylation in Wilms tumors of pericentromeric DNA in chromosomes 1 and 16
    • Qu, G.Z., P.E. GRUNDY, A. NARAYAN & M. EHRLICH. 1999. Frequent hypomethylation in Wilms tumors of pericentromeric DNA in chromosomes 1 and 16. Cancer Genet. Cytogenet. 109(1): 34-39.
    • (1999) Cancer Genet. Cytogenet. , vol.109 , Issue.1 , pp. 34-39
    • Qu, G.Z.1    Grundy, P.E.2    Narayan, A.3    Ehrlich, M.4
  • 41
    • 0022457636 scopus 로고
    • Patterns of DNA methylation and gene expression in human tumor cell lines
    • CHANDLER, L.A., Y.A. DECLERCK, E. BOGENMANN & P.A. JONES. 1986. Patterns of DNA methylation and gene expression in human tumor cell lines. Cancer Res. 46(6): 2944-2949.
    • (1986) Cancer Res. , vol.46 , Issue.6 , pp. 2944-2949
    • Chandler, L.A.1    Declerck, Y.A.2    Bogenmann, E.3    Jones, P.A.4
  • 42
    • 0030846212 scopus 로고    scopus 로고
    • Alterations in DNA methylation: A fundamental aspect of neoplasia
    • BAYLIN, S.B., J.G. HERMAN, J.R. GRAFF, et al. 1998. Alterations in DNA methylation: a fundamental aspect of neoplasia. Adv. Cancer Res, 72: 141-196.
    • (1998) Adv. Cancer Res. , vol.72 , pp. 141-196
    • Baylin, S.B.1    Herman, J.G.2    Graff, J.R.3
  • 43
    • 0032960181 scopus 로고    scopus 로고
    • Cancer epigenetics comes of age
    • JONES, P.A. & P.W. LAIRD. 1999. Cancer epigenetics comes of age. Nat. Genet. 21(2):163-167.
    • (1999) Nat. Genet. , vol.21 , Issue.2 , pp. 163-167
    • Jones, P.A.1    Laird, P.W.2
  • 44
    • 0022620503 scopus 로고
    • DNA methylation and Cancer
    • JONES, P.A. 1986. DNA methylation and Cancer. Cancer Res. 46(2): 461-466.
    • (1986) Cancer Res. , vol.46 , Issue.2 , pp. 461-466
    • Jones, P.A.1
  • 45
    • 0020627846 scopus 로고
    • Hypomethylation of ras oncogenes in primary human cancers
    • FEINBERG, A.P. & B. VOGELSTEIN. 1983. Hypomethylation of ras oncogenes in primary human cancers. Biochem. Biophys. Res. Commun. 111(1): 47-54.
    • (1983) Biochem. Biophys. Res. Commun. , vol.111 , Issue.1 , pp. 47-54
    • Feinberg, A.P.1    Vogelstein, B.2
  • 46
    • 0028299985 scopus 로고
    • Hypomethylation of CCGG sites in the 3′ region of H-ras protooncogene is frequent and is associated with H-ras allele loss in non-small cell lung cancer
    • VACHTENHEIM, J., I. HORAKOVA & H. NOVOTNA. 1994. Hypomethylation of CCGG sites in the 3′ region of H-ras protooncogene is frequent and is associated with H-ras allele loss in non-small cell lung cancer. Cancer Res. 54(5): 1145-1148.
    • (1994) Cancer Res. , vol.54 , Issue.5 , pp. 1145-1148
    • Vachtenheim, J.1    Horakova, I.2    Novotna, H.3
  • 47
    • 0021748312 scopus 로고
    • Hypomethylation of DNA in human cancer cells: A site-specific change in the c-myc oncogene
    • CHEAH, M.S., C.D. WALLACE & R.M. HOFFMAN. 1984. Hypomethylation of DNA in human cancer cells: a site-specific change in the c-myc oncogene. J. Natl. Cancer Inst. 73(5): 1057-1065.
    • (1984) J. Natl. Cancer Inst. , vol.73 , Issue.5 , pp. 1057-1065
    • Cheah, M.S.1    Wallace, C.D.2    Hoffman, R.M.3
  • 48
    • 0022401482 scopus 로고
    • Hypomethylation of c-myc and epidermal growth factor receptor genes in human hepatocellular carcinoma and fetal liver
    • KANEKO, Y., M. SHIBUYA, T. NAKAYAMA, et al. 1985. Hypomethylation of c-myc and epidermal growth factor receptor genes in human hepatocellular carcinoma and fetal liver. Jpn. J. Cancer Res. 76(12): 1136-1140.
    • (1985) Jpn. J. Cancer Res. , vol.76 , Issue.12 , pp. 1136-1140
    • Kaneko, Y.1    Shibuya, M.2    Nakayama, T.3
  • 49
    • 0024605537 scopus 로고
    • Studies on hypomethylation of liver DNA during early stages of chemical carcinogenesis in rat liver
    • RAO, P.M., A. ANTONY, S. RAJALAKSHMI & D.S. SARMA. 1989. Studies on hypomethylation of liver DNA during early stages of chemical carcinogenesis in rat liver. Carcinogenesis 10(5): 933-937.
    • (1989) Carcinogenesis , vol.10 , Issue.5 , pp. 933-937
    • Rao, P.M.1    Antony, A.2    Rajalakshmi, S.3    Sarma, D.S.4
  • 50
    • 0027483559 scopus 로고
    • Methylation status within exon 3 of the c-myc gene as a prognostic marker in myeloma and leukaemia
    • STEPHENSON, J., R. AKDAG, N. OZBEK & G.J. MUFTI. 1993. Methylation status within exon 3 of the c-myc gene as a prognostic marker in myeloma and leukaemia. Leuk. Res. 17(3): 291-293.
    • (1993) Leuk. Res. , vol.17 , Issue.3 , pp. 291-293
    • Stephenson, J.1    Akdag, R.2    Ozbek, N.3    Mufti, G.J.4
  • 51
    • 0028356046 scopus 로고
    • Alterations in the methylation status and expression of the raf oncogene in phenobarbital-induced and spontaneous B6C3F1 mouse live tumors
    • RAY, J.S., M.L. HARBISON, R.M. MCCLAIN & J.I. GOODMAN. 1994. Alterations in the methylation status and expression of the raf oncogene in phenobarbital-induced and spontaneous B6C3F1 mouse live tumors. Mol. Carcinogen. 9(3): 155-166.
    • (1994) Mol. Carcinogen. , vol.9 , Issue.3 , pp. 155-166
    • Ray, J.S.1    Harbison, M.L.2    McClain, R.M.3    Goodman, J.I.4
  • 52
    • 0024849796 scopus 로고
    • Hypomethylation of ras oncogenes in chemically induced and spontaneous B6C3F1 mouse liver tumors
    • VORCE, R.L. & J.I. GOODMAN. 1989. Hypomethylation of ras oncogenes in chemically induced and spontaneous B6C3F1 mouse liver tumors. Mol. Toxicol. 2(2): 99-116.
    • (1989) Mol. Toxicol. , vol.2 , Issue.2 , pp. 99-116
    • Vorce, R.L.1    Goodman, J.I.2
  • 53
    • 0024437998 scopus 로고
    • Altered methylation of ras oncogenes in benzidine-induced B6C3F1 mouse liver tumors
    • VORCE, R.L. & J.I. GOODMAN. 1989. Altered methylation of ras oncogenes in benzidine-induced B6C3F1 mouse liver tumors. Toxicol. Appl. Pharmacol. 100(3): 398-410.
    • (1989) Toxicol. Appl. Pharmacol. , vol.100 , Issue.3 , pp. 398-410
    • Vorce, R.L.1    Goodman, J.I.2
  • 54
    • 0025951624 scopus 로고
    • Hypomethylation of ras oncogenes in chemically induced and spontaneous B6C3F1 mouse liver tumors
    • VORCE, R.L. & J.I. GOODMAN. 1991. Hypomethylation of ras oncogenes in chemically induced and spontaneous B6C3F1 mouse liver tumors. J. Toxicol. Environ. Health 34(3): 367-384.
    • (1991) J. Toxicol. Environ. Health , vol.34 , Issue.3 , pp. 367-384
    • Vorce, R.L.1    Goodman, J.I.2
  • 55
    • 0027239823 scopus 로고
    • bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia
    • HANADA, M., D. DELIA, A. AIELLO, et al. 1993. bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia: Blood 82(6): 1820-1828.
    • (1993) Blood , vol.82 , Issue.6 , pp. 1820-1828
    • Hanada, M.1    Delia, D.2    Aiello, A.3
  • 56
    • 0035870248 scopus 로고    scopus 로고
    • A gene hypermethylation profile of human cancer
    • ESTELLER, M., P.G. CORN, S.B. BAYLIN & J.G. HERMAN. 2001. A gene hypermethylation profile of human cancer. Cancer Res. 61(8): 3225-3229.
    • (2001) Cancer Res. , vol.61 , Issue.8 , pp. 3225-3229
    • Esteller, M.1    Corn, P.G.2    Baylin, S.B.3    Herman, J.G.4
  • 57
    • 0343621494 scopus 로고    scopus 로고
    • Aberrant CpG-island methylation has non-random and tumour-type-specific patterns
    • COSTELLO, J.F., M.C. FRUHWALD, D.J. SMIRAGLIA, et al. 2000. Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat. Genet. 24(2): 132-138.
    • (2000) Nat. Genet. , vol.24 , Issue.2 , pp. 132-138
    • Costello, J.F.1    Fruhwald, M.C.2    Smiraglia, D.J.3
  • 58
    • 0019944097 scopus 로고
    • Methylation and gene control
    • FELSENFELD, G. & J. MCGHEE. 1982. Methylation and gene control. Nature 296(5858): 602-603.
    • (1982) Nature , vol.296 , Issue.5858 , pp. 602-603
    • Felsenfeld, G.1    McGhee, J.2
  • 61
    • 0028359711 scopus 로고
    • The topology of the promoter of RNA polymerase II- and III-transcribed genes is modified by the methylation of 5′-CG-3′ dinucleotides
    • MUIZNIEKS, I. & W. DOERFLER. 1994. The topology of the promoter of RNA polymerase II- and III-transcribed genes is modified by the methylation of 5′-CG-3′ dinucleotides. Nucleic Acids Res. 22(13): 2568-2575.
    • (1994) Nucleic Acids Res. , vol.22 , Issue.13 , pp. 2568-2575
    • Muiznieks, I.1    Doerfler, W.2
  • 62
    • 0033547330 scopus 로고    scopus 로고
    • Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene
    • Xu, G.L., T.H. BESTOR, D. BOURC'HIS, et al. 1999. Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene. Nature 402(6758): 187-191.
    • (1999) Nature , vol.402 , Issue.6758 , pp. 187-191
    • Xu, G.L.1    Bestor, T.H.2    Bourc'his, D.3
  • 63
    • 0032480226 scopus 로고    scopus 로고
    • DNA hypomethylation leads to elevated mutation rates
    • CHEN, R.Z., U. PETTERSSON, C. BEARD, et al. 1998. DNA hypomethylation leads to elevated mutation rates. Nature 395(6697): 89-93.
    • (1998) Nature , vol.395 , Issue.6697 , pp. 89-93
    • Chen, R.Z.1    Pettersson, U.2    Beard, C.3
  • 64
    • 0030867514 scopus 로고    scopus 로고
    • DNA demethylation and pericentromeric rearrangements of chromosome 1
    • JI, W., R. HERNANDEZ, X.Y. ZHANG, et al. 1997. DNA demethylation and pericentromeric rearrangements of chromosome 1. Mutat. Res. 379(1): 33-41.
    • (1997) Mutat. Res. , vol.379 , Issue.1 , pp. 33-41
    • Ji, W.1    Hernandez, R.2    Zhang, X.Y.3
  • 65
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • NOWELL, P.C. 1976. The clonal evolution of tumor cell populations. Science 194(4260): 23-28.
    • (1976) Science , vol.194 , Issue.4260 , pp. 23-28
    • Nowell, P.C.1
  • 66
    • 0023897656 scopus 로고
    • Evolution of cancer genes as a mutation-driven process
    • TEMIN, H.M. 1988. Evolution of cancer genes as a mutation-driven process. Cancer Res. 48(7): 1697-1701.
    • (1988) Cancer Res. , vol.48 , Issue.7 , pp. 1697-1701
    • Temin, H.M.1
  • 67
    • 0023610044 scopus 로고
    • DNA methylation and epigenetic defects in carcinogenesis
    • HOLLIDAY, R. 1987. DNA methylation and epigenetic defects in carcinogenesis. Mutat. Res. 181(2): 215-217.
    • (1987) Mutat. Res. , vol.181 , Issue.2 , pp. 215-217
    • Holliday, R.1
  • 68
    • 0033804699 scopus 로고    scopus 로고
    • Somatic mutations and ageing
    • HOLLIDAY, R. 2000. Somatic mutations and ageing. Mutat Res. 463(3): 173-178.
    • (2000) Mutat Res. , vol.463 , Issue.3 , pp. 173-178
    • Holliday, R.1
  • 69
    • 0018936840 scopus 로고
    • Transposable genetic elements
    • COHEN, S.N. & J.A. SHAPIRO. 1980. Transposable genetic elements. Sci. Am. 242(2):40-49.
    • (1980) Sci. Am. , vol.242 , Issue.2 , pp. 40-49
    • Cohen, S.N.1    Shapiro, J.A.2
  • 70
    • 0025034313 scopus 로고
    • P element transposition
    • CRAIG, N.L. 1990. P element transposition. Cell 62(3): 399-402.
    • (1990) Cell , vol.62 , Issue.3 , pp. 399-402
    • Craig, N.L.1
  • 71
    • 0030965737 scopus 로고    scopus 로고
    • What restricts the activity of mariner-like transposable elements
    • HARTL, D.L., E.R. LOZOVSKAYA, D.I. NURMINSKY & A.R. LOHE. 1997. What restricts the activity of mariner-like transposable elements. Trends Genet. 13(5): 197-201.
    • (1997) Trends Genet. , vol.13 , Issue.5 , pp. 197-201
    • Hartl, D.L.1    Lozovskaya, E.R.2    Nurminsky, D.I.3    Lohe, A.R.4
  • 72
    • 0034265758 scopus 로고    scopus 로고
    • Genetics. Transposons help sculpt a dynamic genome
    • MOFFAT, A.S. 2000. Genetics. Transposons help sculpt a dynamic genome. Science 289(5484): 1455-1457.
    • (2000) Science , vol.289 , Issue.5484 , pp. 1455-1457
    • Moffat, A.S.1
  • 73
    • 0020488516 scopus 로고
    • Transposable elements, hybrid incompatibility and speciation
    • ISH-HOROWICZ, D. 1982. Transposable elements, hybrid incompatibility and speciation. Nature 299(5885): 676-677.
    • (1982) Nature , vol.299 , Issue.5885 , pp. 676-677
    • Ish-Horowicz, D.1
  • 74
    • 0026331048 scopus 로고
    • Isolation of an active human transposable element
    • DOMBROSKI, B.A., S.L. MATHIAS, E. NANTHAKUMAR, et al. 1991. Isolation of an active human transposable element. Science 254(5039): 1805-1808.
    • (1991) Science , vol.254 , Issue.5039 , pp. 1805-1808
    • Dombroski, B.A.1    Mathias, S.L.2    Nanthakumar, E.3
  • 75
    • 8944258929 scopus 로고    scopus 로고
    • Dysfunction of the Orleans reeler gene arising from exon skipping due to transposition of a full-length copy of an active L1 sequence into the skipped exon
    • TAKAHARA, T., T. OHSUMI, J. KUROMITSU, et al. 1996. Dysfunction of the Orleans reeler gene arising from exon skipping due to transposition of a full-length copy of an active L1 sequence into the skipped exon. Hum. Mol. Genet. 5(7): 989-993.
    • (1996) Hum. Mol. Genet. , vol.5 , Issue.7 , pp. 989-993
    • Takahara, T.1    Ohsumi, T.2    Kuromitsu, J.3
  • 76
    • 0034674604 scopus 로고    scopus 로고
    • Reversal of fortune for Drosophila geneticists?
    • ENGELS, W.R. 2000. Reversal of fortune for Drosophila geneticists? Science 288(5473): 1973-1975.
    • (2000) Science , vol.288 , Issue.5473 , pp. 1973-1975
    • Engels, W.R.1
  • 77
    • 0021099309 scopus 로고
    • Retroviruses and transposable elements - Which came first?
    • FINNEGAN, D.J. 1983. Retroviruses and transposable elements - which came first? Nature 302(5904): 105-106.
    • (1983) Nature , vol.302 , Issue.5904 , pp. 105-106
    • Finnegan, D.J.1
  • 78
    • 0020663784 scopus 로고
    • Retrovirus-like particles containing RNA homologous to the transposable element copia in Drosophila melanogaster
    • SHIBA, T. & K. SAIGO. 1983. Retrovirus-like particles containing RNA homologous to the transposable element copia in Drosophila melanogaster. Nature 302(5904): 119-124.
    • (1983) Nature , vol.302 , Issue.5904 , pp. 119-124
    • Shiba, T.1    Saigo, K.2
  • 79
    • 0026428975 scopus 로고
    • Reverse transcriptase encoded by a human transposable element
    • MATHIAS, S.L., A.F. SCOTT, H.H. KAZAZIAN, Jr., et al. 1991. Reverse transcriptase encoded by a human transposable element. Science 254(5039): 1808-1810.
    • (1991) Science , vol.254 , Issue.5039 , pp. 1808-1810
    • Mathias, S.L.1    Scott, A.F.2    Kazazian H.H., Jr.3
  • 80
    • 0034682732 scopus 로고    scopus 로고
    • Genetics. L1 retrotransposons shape the mammalian genome
    • KAZAZIAN, H.H., Jr. 2000. Genetics. L1 retrotransposons shape the mammalian genome. Science 289(5482): 1152-1153.
    • (2000) Science , vol.289 , Issue.5482 , pp. 1152-1153
    • Kazazian H.H., Jr.1
  • 81
    • 0030591769 scopus 로고    scopus 로고
    • Differential methylation of human LINE-1 retrotransposons in malignant cells
    • ALVES, G., A. TATRO & T. FANNING. 1996. Differential methylation of human LINE-1 retrotransposons in malignant cells. Gene 176(1-2): 39-44.
    • (1996) Gene , vol.176 , Issue.1-2 , pp. 39-44
    • Alves, G.1    Tatro, A.2    Fanning, T.3
  • 82
    • 0030115772 scopus 로고    scopus 로고
    • Creation of genomic methylation patterns
    • BESTOR, T.H. & B. TYCKO. 1996. Creation of genomic methylation patterns. Nat. Genet. 12(4): 363-367.
    • (1996) Nat. Genet. , vol.12 , Issue.4 , pp. 363-367
    • Bestor, T.H.1    Tycko, B.2
  • 83
    • 0029998065 scopus 로고    scopus 로고
    • Genetic analysis of genomic methylation patterns in plants and mammals
    • YODER, J.A. & T.H. BESTOR. 1996. Genetic analysis of genomic methylation patterns in plants and mammals. Biol. Chem. 377(10): 605-610.
    • (1996) Biol. Chem. , vol.377 , Issue.10 , pp. 605-610
    • Yoder, J.A.1    Bestor, T.H.2
  • 84
    • 0030840954 scopus 로고    scopus 로고
    • Cytosine methylation and the ecology of intragenomic parasites
    • YODER, J.A., C.P. WALSH & T.H. BESTOR. 1997. Cytosine methylation and the ecology of intragenomic parasites. Trends Genet. 13(8): 335-340.
    • (1997) Trends Genet. , vol.13 , Issue.8 , pp. 335-340
    • Yoder, J.A.1    Walsh, C.P.2    Bestor, T.H.3
  • 85
    • 0039410919 scopus 로고
    • DNA methylation in adenovirus, adenovirus-transformed cells, and host cells
    • GUNTHERT, U., M. SCHWEIGER, M. STUPP & W. DOERFLER. 1976. DNA methylation in adenovirus, adenovirus-transformed cells, and host cells. Proc. Natl. Acad. Sci. USA 73(11): 3923-3927.
    • (1976) Proc. Natl. Acad. Sci. USA , vol.73 , Issue.11 , pp. 3923-3927
    • Gunthert, U.1    Schweiger, M.2    Stupp, M.3    Doerfler, W.4
  • 86
    • 0018648142 scopus 로고
    • Methylation of Herpesvirus saimiri DNA in lymphoid tumor cell lines
    • DESROSIERS, R.C., C. MULDER & B. FLECKENSTEIN. 1979. Methylation of Herpesvirus saimiri DNA in lymphoid tumor cell lines. Proc. Natl. Acad. Sci. USA 76(8): 3839-3843.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , Issue.8 , pp. 3839-3843
    • Desrosiers, R.C.1    Mulder, C.2    Fleckenstein, B.3
  • 87
    • 0019136561 scopus 로고
    • DNA methylation and viral gene expression in adenovirus-transformed and -infected cells
    • VARDIMON, L., R. NEUMANN, I. KUHLMANN, et al. 1980. DNA methylation and viral gene expression in adenovirus-transformed and -infected cells. Nucleic Acids Res. 8(11): 2461-2473.
    • (1980) Nucleic Acids Res. , vol.8 , Issue.11 , pp. 2461-2473
    • Vardimon, L.1    Neumann, R.2    Kuhlmann, I.3
  • 88
    • 0018714759 scopus 로고
    • Methylation of integrated viral DNA sequences in hamster cells transformed by adenovirus 12
    • SUTTER, D. & W. DOERFLER. 1980. Methylation of integrated viral DNA sequences in hamster cells transformed by adenovirus 12. Cold Spring Harbor Symp. Quant. Biol. 44(Pt. 1): 565-568.
    • (1980) Cold Spring Harbor Symp. Quant. Biol. , vol.44 , Issue.PART 1 , pp. 565-568
    • Sutter, D.1    Doerfler, W.2
  • 89
    • 0019786495 scopus 로고
    • DNA methylation and gene expression: Endogenous retroviral genome becomes infectious after molecular cloning
    • HARBERS, K., A. SCHNIEKE, H. STUHLMANN, et al. 1981. DNA methylation and gene expression: endogenous retroviral genome becomes infectious after molecular cloning. Proc. Natl. Acad. Sci. USA 78(12): 7609-7613.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , Issue.12 , pp. 7609-7613
    • Harbers, K.1    Schnieke, A.2    Stuhlmann, H.3
  • 90
    • 0020283636 scopus 로고
    • DNA methylation, retroviruses, and embryogenesis
    • JAENISCH, R., K. HARBERS, D. JAHNER, et al. 1982. DNA methylation, retroviruses, and embryogenesis. J. Cell Biochem. 20(4): 331-336.
    • (1982) J. Cell Biochem. , vol.20 , Issue.4 , pp. 331-336
    • Jaenisch, R.1    Harbers, K.2    Jahner, D.3
  • 91
    • 0020048308 scopus 로고
    • De novo methylation and expression of retroviral genomes during mouse embryogenesis
    • JAHNER, D., H. STUHLMANN, C.L. STEWART, et al. 1982. De novo methylation and expression of retroviral genomes during mouse embryogenesis. Nature 298(5875): 623-628.
    • (1982) Nature , vol.298 , Issue.5875 , pp. 623-628
    • Jahner, D.1    Stuhlmann, H.2    Stewart, C.L.3
  • 92
    • 0020338313 scopus 로고
    • The unmethylated state of the promoter/leader and 5′-regions of integrated adenovirus genes correlates with gene expression
    • KRUCZEK, I. & W. DOERFLER. 1982. The unmethylated state of the promoter/leader and 5′-regions of integrated adenovirus genes correlates with gene expression. EMBO J. 1(4): 409-414.
    • (1982) EMBO J. , vol.1 , Issue.4 , pp. 409-414
    • Kruczek, I.1    Doerfler, W.2
  • 93
    • 0020520385 scopus 로고
    • Retrovirus genomes methylated by mammalian but not bacterial methylase are non-infectious
    • SIMON, D., H. STUHLMANN, D. JAHNER, et al. 1983. Retrovirus genomes methylated by mammalian but not bacterial methylase are non-infectious. Nature 304(5923): 275-277.
    • (1983) Nature , vol.304 , Issue.5923 , pp. 275-277
    • Simon, D.1    Stuhlmann, H.2    Jahner, D.3
  • 94
    • 0019816525 scopus 로고
    • Infectivity and methylation of retroviral genomes is correlated with expression in the animal
    • STUHLMANN, H., D. JAHNER & R. JAENISCH. 1981. Infectivity and methylation of retroviral genomes is correlated with expression in the animal. Cell 26(2 Pt. 2): 221-232.
    • (1981) Cell , vol.26 , Issue.2 PART 2 , pp. 221-232
    • Stuhlmann, H.1    Jahner, D.2    Jaenisch, R.3
  • 95
    • 0033582623 scopus 로고    scopus 로고
    • Nonmethylated transposable elements and methylated genes in a chordate genome
    • SIMMEN, M.W., S. LEITGEB, J. CHARLTON, et al. 1999. Nonmethylated transposable elements and methylated genes in a chordate genome. Science 283(5405): 1164-1167.
    • (1999) Science , vol.283 , Issue.5405 , pp. 1164-1167
    • Simmen, M.W.1    Leitgeb, S.2    Charlton, J.3
  • 97
    • 0034003798 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer
    • TYCKO, B. 2000. Epigenetic gene silencing in cancer. J. Clin. Invest. 105(4): 401-407.
    • (2000) J. Clin. Invest. , vol.105 , Issue.4 , pp. 401-407
    • Tycko, B.1
  • 98
    • 0033566704 scopus 로고    scopus 로고
    • Mosaic allelic insulin-like growth factor 2 expression patterns reveal a link between Wilms' tumorigenesis and epigenetic heterogeneity
    • OHLSSON, R., H. CUI, L. HE, et al. 1999. Mosaic allelic insulin-like growth factor 2 expression patterns reveal a link between Wilms' tumorigenesis and epigenetic heterogeneity. Cancer Res. 59(16): 3889-3892.
    • (1999) Cancer Res. , vol.59 , Issue.16 , pp. 3889-3892
    • Ohlsson, R.1    Cui, H.2    He, L.3
  • 99
    • 0034037026 scopus 로고    scopus 로고
    • Genomic imprinting and environmental disease susceptibility
    • JIRTLE, R.L., M. SANDER & J.C. BARRETT. 2000. Genomic imprinting and environmental disease susceptibility. Environ. Health Perspect. 108(3): 271-278.
    • (2000) Environ. Health Perspect. , vol.108 , Issue.3 , pp. 271-278
    • Jirtle, R.L.1    Sander, M.2    Barrett, J.C.3
  • 100
    • 0014241870 scopus 로고
    • Effect of 5-aza-2′-deoxycytidine against leukemic and hemopoietic tissues in AKR mice
    • SORM, F. & J. VESELY. 1968. Effect of 5-aza-2′-deoxycytidine against leukemic and hemopoietic tissues in AKR mice. Neoplasma 15(4): 339-343.
    • (1968) Neoplasma , vol.15 , Issue.4 , pp. 339-343
    • Sorm, F.1    Vesely, J.2
  • 101
    • 0018078643 scopus 로고
    • Effects of 5-aza-2′-deoxycytidine on DNA synthesis in mouse lymphatic tissues
    • CIHAK, A. & J. VESELY. 1978. Effects of 5-aza-2′-deoxycytidine on DNA synthesis in mouse lymphatic tissues. Neoplasma 25(4): 385-393.
    • (1978) Neoplasma , vol.25 , Issue.4 , pp. 385-393
    • Cihak, A.1    Vesely, J.2
  • 102
    • 0022262271 scopus 로고
    • Effects of 5-azacytidine and its 2′-deoxyderivative on cell differentiation and DNA methylation
    • JONES, P.A. 1985. Effects of 5-azacytidine and its 2′-deoxyderivative on cell differentiation and DNA methylation. Pharmacol Ther. 28(1): 17-27.
    • (1985) Pharmacol Ther. , vol.28 , Issue.1 , pp. 17-27
    • Jones, P.A.1
  • 103
    • 0022032204 scopus 로고
    • Altering gene expression with 5-azacytidine
    • JONES, P.A. 1985. Altering gene expression with 5-azacytidine. Cell 40(3): 485-486.
    • (1985) Cell , vol.40 , Issue.3 , pp. 485-486
    • Jones, P.A.1
  • 104
    • 0030938184 scopus 로고    scopus 로고
    • Pharmacological approach for optimization of the dose schedule of 5-Aza-2′-deoxycytidine (Decitabine) for the therapy of leukemia
    • MOMPARLER, R.L., S. COTE & N. ELIOPOULOS. 1997. Pharmacological approach for optimization of the dose schedule of 5-Aza-2′-deoxycytidine (Decitabine) for the therapy of leukemia. Leukemia 11(Suppl. 1): S1-S6.
    • (1997) Leukemia , vol.11 , Issue.SUPPL. 1
    • Momparler, R.L.1    Cote, S.2    Eliopoulos, N.3
  • 105
    • 0036194094 scopus 로고    scopus 로고
    • Vitamin A and its derivatives induce hepatic glycine N-methyltransferase and hypomethylation of DNA in rats
    • ROWLING, M.J., M.H. MCMULLEN & K.L. SCHALINSKE. 2002. Vitamin A and its derivatives induce hepatic glycine N-methyltransferase and hypomethylation of DNA in rats. J. Nutr. 132(3): 365-369.
    • (2002) J. Nutr. , vol.132 , Issue.3 , pp. 365-369
    • Rowling, M.J.1    McMullen, M.H.2    Schalinske, K.L.3
  • 106
    • 0031816123 scopus 로고    scopus 로고
    • Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women
    • JACOB, R.A., D.M. GRETZ, P.C. TAYLOR, et al. 1998. Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women. J. Nutr. 128(7): 1204-1212.
    • (1998) J. Nutr. , vol.128 , Issue.7 , pp. 1204-1212
    • Jacob, R.A.1    Gretz, D.M.2    Taylor, P.C.3
  • 107
    • 0033805888 scopus 로고    scopus 로고
    • Genomic DNA methylation decreases in response to moderate folate depletion in elderly women
    • RAMPERSAUD, G.C., G.P. KAUWELL, A.D. HUTSON, et al. 2000. Genomic DNA methylation decreases in response to moderate folate depletion in elderly women. Am. J. Clin. Nutr. 72(4): 998-1003.
    • (2000) Am. J. Clin. Nutr. , vol.72 , Issue.4 , pp. 998-1003
    • Rampersaud, G.C.1    Kauwell, G.P.2    Hutson, A.D.3
  • 108
    • 0027286578 scopus 로고
    • Folate, methionine, and alcohol intake and risk of colorectal adenoma
    • GIOVANNUCCI, E., M.J. STAMPFER, G.A. COLDITZ, et al. 1993. Folate, methionine, and alcohol intake and risk of colorectal adenoma. J. Natl. Cancer Inst. 85(11): 875-884.
    • (1993) J. Natl. Cancer Inst. , vol.85 , Issue.11 , pp. 875-884
    • Giovannucci, E.1    Stampfer, M.J.2    Colditz, G.A.3
  • 109
    • 0032190337 scopus 로고    scopus 로고
    • Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study
    • GIOVANNUCCI, E., M.J. STAMPFER, G.A. COLDITZ, et al. 1998. Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study. Ann. Intern. Med. 129(7): 517-524.
    • (1998) Ann. Intern. Med. , vol.129 , Issue.7 , pp. 517-524
    • Giovannucci, E.1    Stampfer, M.J.2    Colditz, G.A.3
  • 110
    • 0036227447 scopus 로고    scopus 로고
    • The influence of folate and multivitamin use on the familial risk of colon cancer in women
    • FUCHS, C.S., W.C. WILLETT, G.A. COLDITZ, et al. 2002. The influence of folate and multivitamin use on the familial risk of colon cancer in women. Cancer Epidemiol. Biomarkers Prev. 11(3): 227-234.
    • (2002) Cancer Epidemiol. Biomarkers Prev. , vol.11 , Issue.3 , pp. 227-234
    • Fuchs, C.S.1    Willett, W.C.2    Colditz, G.A.3
  • 111
    • 0030615085 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer
    • MA, J., M.J. STAMPFER, E. GIOVANNUCCI, et al. 1997. Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer. Cancer Res. 57(6): 1098-1102.
    • (1997) Cancer Res. , vol.57 , Issue.6 , pp. 1098-1102
    • Ma, J.1    Stampfer, M.J.2    Giovannucci, E.3
  • 112
    • 0033526312 scopus 로고    scopus 로고
    • A prospective study of folate intake and the risk of breast cancer
    • ZHANG, S., D.J. HUNTER, S.E. HANKINSON, et al. 1999. A prospective study of folate intake and the risk of breast cancer. JAMA 281(17): 1632-1637.
    • (1999) JAMA , vol.281 , Issue.17 , pp. 1632-1637
    • Zhang, S.1    Hunter, D.J.2    Hankinson, S.E.3
  • 113
    • 0027256637 scopus 로고
    • Reversibility of changes in nucleic acid methylation and gene expression induced in rat liver by severe dietary methyl deficiency
    • CHRISTMAN, J.K., G. SHEIKHNEJAD, M. DIZIK, et al. 1993. Reversibility of changes in nucleic acid methylation and gene expression induced in rat liver by severe dietary methyl deficiency. Carcinogenesis 14(4): 551-557.
    • (1993) Carcinogenesis , vol.14 , Issue.4 , pp. 551-557
    • Christman, J.K.1    Sheikhnejad, G.2    Dizik, M.3
  • 114
    • 0035214369 scopus 로고    scopus 로고
    • Impact of extracellular folate levels on global gene expression
    • JHAVERI, M.S., C. WAGNER & J.B. TREPEL. 2001. Impact of extracellular folate levels on global gene expression. Mol. Pharmacol. 60(6): 1288-1295.
    • (2001) Mol. Pharmacol. , vol.60 , Issue.6 , pp. 1288-1295
    • Jhaveri, M.S.1    Wagner, C.2    Trepel, J.B.3
  • 115
    • 0034533186 scopus 로고    scopus 로고
    • Dietary selenium and arsenic affect DNA methylation in vitro in Caco-2 cells and in vivo in rat liver and colon
    • DAVIS, C.D., E.O. UTHUS & J.W. FINLEY. 2000. Dietary selenium and arsenic affect DNA methylation in vitro in Caco-2 cells and in vivo in rat liver and colon. J. Nutr. 130(12): 2903-2909.
    • (2000) J. Nutr. , vol.130 , Issue.12 , pp. 2903-2909
    • Davis, C.D.1    Uthus, E.O.2    Finley, J.W.3
  • 116
    • 0021972234 scopus 로고
    • Effect of zinc deficiency on methionine metabolism, methylation reactions and protein synthesis in isolated perfused rat liver
    • WALLWORK, J.C. & J.A. DUERRE. 1985. Effect of zinc deficiency on methionine metabolism, methylation reactions and protein synthesis in isolated perfused rat liver. J. Nutr. 115(2): 252-262.
    • (1985) J. Nutr. , vol.115 , Issue.2 , pp. 252-262
    • Wallwork, J.C.1    Duerre, J.A.2
  • 117
    • 0031869119 scopus 로고    scopus 로고
    • Inhibition of DNA cytosine methyltransferase by chemopreventive selenium compounds, determined by an improved assay for DNA cytosine methyltransferase and DNA cytosine methylation
    • FIALA, E.S., M.E. STARETZ, G.A. PANDYA, et al. 1998. Inhibition of DNA cytosine methyltransferase by chemopreventive selenium compounds, determined by an improved assay for DNA cytosine methyltransferase and DNA cytosine methylation. Carcinogenesis 19(4): 597-604.
    • (1998) Carcinogenesis , vol.19 , Issue.4 , pp. 597-604
    • Fiala, E.S.1    Staretz, M.E.2    Pandya, G.A.3
  • 118
    • 0036170179 scopus 로고    scopus 로고
    • Dietary selenite and azadeoxycytidine treatments affect dimethylhydrazine-induced aberrant crypt formation in rat colon and DNA methylation in HT-29 cells
    • DAVIS, C.D. & E.O. UTHUS. 2002. Dietary selenite and azadeoxycytidine treatments affect dimethylhydrazine-induced aberrant crypt formation in rat colon and DNA methylation in HT-29 cells. J. Nutr. 132(2): 292-297.
    • (2002) J. Nutr. , vol.132 , Issue.2 , pp. 292-297
    • Davis, C.D.1    Uthus, E.O.2
  • 119
    • 0020638422 scopus 로고
    • DNA methylation decreases in aging but not in immortal cells
    • WILSON, V.L. & P.A. JONES. 1983. DNA methylation decreases in aging but not in immortal cells. Science 220(4601): 1055-1057.
    • (1983) Science , vol.220 , Issue.4601 , pp. 1055-1057
    • Wilson, V.L.1    Jones, P.A.2
  • 121
    • 0023664725 scopus 로고
    • Genomic 5-Methyldeoxycytidine decreases with age
    • WILSON, V.L., R.A. SMITH, S. MA & R.G. CUTLER. 1987. Genomic 5-methyldeoxycytidine decreases with age. J. Biol. Chem. 262(21): 9948-9951.
    • (1987) J. Biol. Chem. , vol.262 , Issue.21 , pp. 9948-9951
    • Wilson, V.L.1    Smith, R.A.2    Ma, S.3    Cutler, R.G.4
  • 122
    • 0032845215 scopus 로고    scopus 로고
    • Aging, DNA methylation and cancer
    • ISSA, J.P. 1999. Aging, DNA methylation and cancer. Crit. Rev. Oncol. Hematol. 32(1): 31-43.
    • (1999) Crit. Rev. Oncol. Hematol. , vol.32 , Issue.1 , pp. 31-43
    • Issa, J.P.1
  • 123
    • 0024552485 scopus 로고
    • Human lymphocytes aged in vivo have reduced levels of methylation in transcriptionally active and inactive DNA
    • DRINKWATER, R.D., T.J. BLAKE, A.A. MORLEY & D.R. TURNER. 1989. Human lymphocytes aged in vivo have reduced levels of methylation in transcriptionally active and inactive DNA. Mutat. Res. 219(1): 29-37.
    • (1989) Mutat. Res. , vol.219 , Issue.1 , pp. 29-37
    • Drinkwater, R.D.1    Blake, T.J.2    Morley, A.A.3    Turner, D.R.4
  • 124
    • 0024546311 scopus 로고
    • Age-associated changes in DNA methylation and mRNA level of the c-myc gene in spleen and liver of mice
    • ONO, T., N. TAKAHASHI & S. OKADA. 1989. Age-associated changes in DNA methylation and mRNA level of the c-myc gene in spleen and liver of mice. Mutat. Res. 219(1): 39-50.
    • (1989) Mutat. Res. , vol.219 , Issue.1 , pp. 39-50
    • Ono, T.1    Takahashi, N.2    Okada, S.3
  • 125
    • 0029063483 scopus 로고
    • Changes of the methylation pattern of the c-myc gene during in vitro aging of IMR90 human embryonic fibroblasts
    • HALLE, J.P., C. SCHMIDT & G. ADAM. 1995. Changes of the methylation pattern of the c-myc gene during in vitro aging of IMR90 human embryonic fibroblasts. Mutat. Res. 316(4): 157-171.
    • (1995) Mutat. Res. , vol.316 , Issue.4 , pp. 157-171
    • Halle, J.P.1    Schmidt, C.2    Adam, G.3
  • 126
    • 0033913645 scopus 로고    scopus 로고
    • Aging, methylation and cancer
    • AHUJA, N. & J.P. ISSA. 2000. Aging, methylation and cancer. Histol. Histopathol. 15(3): 835-842.
    • (2000) Histol. Histopathol. , vol.15 , Issue.3 , pp. 835-842
    • Ahuja, N.1    Issa, J.P.2
  • 127
    • 0025043570 scopus 로고
    • Age-related increase in methylation of ribosomal genes and inactivation of chromosome-specific rRNA gene clusters in mouse
    • SWISSHELM, K., C.M. DISTECHE, J. THORVALDSEN, et al. 1990. Age-related increase in methylation of ribosomal genes and inactivation of chromosome-specific rRNA gene clusters in mouse. Mutat. Res. 237(3-4): 131-146.
    • (1990) Mutat. Res. , vol.237 , Issue.3-4 , pp. 131-146
    • Swisshelm, K.1    Disteche, C.M.2    Thorvaldsen, J.3


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