Lactate dyscrasia: A novel explanation for amyotrophic lateral sclerosis

Neurobiology of Aging

Volumn 33, Issue 3, 2012, Pages 569-581

  Vadakkadath Meethal, Sivan ^a,b   Atwood, Craig S ^a,b,c,d  

^a WILLIAM S MIDDLETON MEMORIAL VETERANS HOSPITAL   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

^d EDITH COWAN UNIVERSITY   (Australia)

Author keywords

Aging; Amyotrophic lateral sclerosis; Aspartate; ATP; Cu Zn superoxide dismutase 1; Estrogen; FALS; Glutamate; Hormone; Lactate; Lactate shuttle; LDH; Lou Gehrig's disease; Malate; Mitochondria; Motoneuron; Muscular atrophy; Neuromuscular junction; Neuronal degeneration; Oxaloacetate; Progesterone; Pyruvate; Respiratory chain; SALS; Sex steroids; Testosterone

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANDROGEN RECEPTOR; GESTAGEN; GLUTAMIC ACID; LACTATE DEHYDROGENASE; LACTIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXALOACETIC ACID; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; RILUZOLE; SEX HORMONE; SUPEROXIDE DISMUTASE;

AGING; AMYGDALOID NUCLEUS; AMYOTROPHIC LATERAL SCLEROSIS; ANTERIOR CINGULATE; CELL INCLUSION; CITRIC ACID CYCLE; COGNITIVE DEFECT; DENERVATION; EXERCISE; GENDER; GLYCOLYSIS; GRIP STRENGTH; HIPPOCAMPUS; HOMEOSTASIS; HUMAN; LACTATE DYSCRASIA; LACTATE HOMEOSTASIS; LACTATE METABOLISM; METABOLISM; MITOCHONDRION; MOLECULAR MODEL; MOTONEURON; MUSCLE INNERVATION; MUSCLE NEURONAL LACTATE SHUTTLE; NERVE CELL NECROSIS; NERVE DEGENERATION; NERVE ENDING; NEUROMUSCULAR SYNAPSE; NEUROPATHOLOGY; NEUROTRANSMITTER RELEASE; NONHUMAN; PARALYSIS; PATHOGENESIS; POSTERIOR CINGULATE; PREFRONTAL CORTEX; PRIORITY JOURNAL; RESPIRATORY CHAIN; REVIEW; TRANSPORT KINETICS; UBIQUITINATED INCLUSION BODY;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; HUMANS; LACTIC ACID; MITOCHONDRIAL DISEASES; NERVE DEGENERATION;

EID: 84855793970     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2010.04.012     Document Type: Review

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