Inhibition of monocarboxylate transporter 2 in the retrotrapezoid nucleus in rats: A test of the astrocyte-neuron lactate-shuttle hypothesis

Journal of Neuroscience

Volumn 28, Issue 19, 2008, Pages 4888-4896

  Erlichman, Joseph S ^a   Hewitt, Amy ^a   Damon, Tracey L ^a   Hart, Michael ^a   Kurascz, Jennifer ^a   Li, Aihua ^b   Leiter, James C ^b  

^a ST LAWRENCE UNIVERSITY   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

Astrocytes; Lactate shuttle; Metabolism; Neurons; pH; Ventilation

Indexed keywords

ALPHA CYANO 4 HYDROXYCINNAMIC ACID; DEOXYGLUCOSE; MONOCARBOXYLATE TRANSPORTER 1; MONOCARBOXYLATE TRANSPORTER 2; MONOCARBOXYLATE TRANSPORTER 4; 2 (N (7 NITROBENZ 2 OXA 1,3 DIAZOL 4 YL)AMINO) 2 DEOXYGLUCOSE; 2-(N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-2-DEOXYGLUCOSE; 4 CHLORO 7 NITROBENZOFURAZAN; ALPHA-CYANO-4-HYDROXYCINNAMATE; COUMARIC ACID; DRUG DERIVATIVE; LACTIC ACID; MONOCARBOXYLATE TRANSPORTER; SLC16A7 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN SLICE; CONTROLLED STUDY; ENZYME INHIBITION; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORY STIMULATION; ANIMAL; BIOLOGICAL MODEL; BREATHING; CHEMORECEPTOR; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; EXTRACELLULAR FLUID; FEMALE; IN VITRO STUDY; INTRACELLULAR MEMBRANE; MALE; MEDULLA OBLONGATA; METABOLISM; PH; SPRAGUE DAWLEY RAT;

4-CHLORO-7-NITROBENZOFURAZAN; ANIMALS; ASTROCYTES; CHEMORECEPTORS; COUMARIC ACIDS; DEOXYGLUCOSE; EXTRACELLULAR FLUID; FEMALE; HYDROGEN-ION CONCENTRATION; INTRACELLULAR MEMBRANES; LACTIC ACID; MALE; MEDULLA OBLONGATA; MODELS, NEUROLOGICAL; MONOCARBOXYLIC ACID TRANSPORTERS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATION;

EID: 44949166565     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5430-07.2008     Document Type: Article

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