Ubiquitin-only intraneuronal inclusion in the substantia nigra is a characteristic feature of motor neurone disease with dementia

Neuropathology and Applied Neurobiology

Volumn 28, Issue 2, 2002, Pages 120-128

  Al Sarraj, S ^a   Maekawa, S ^a   Kibble, M ^a   Everall, I ^a   Leigh, N ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; ANTIBODY; PHOSPHOGLUCOMUTASE; TAU PROTEIN; UBIQUITIN;

ADULT; AGED; ARTICLE; ASTROCYTOSIS; BRAIN CORTEX; BRAIN DEGENERATION; CELL ACTIVATION; CELL DENSITY; CELL INCLUSION; CLINICAL ARTICLE; CONTROLLED STUDY; DEMENTIA; DENTATE GYRUS; DISEASE DURATION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; LEWY BODY; MALE; MICROGLIA; MOTOR NEURON DISEASE; PARKINSON DISEASE; PRIORITY JOURNAL; SPINAL CORD; SUBSTANTIA NIGRA;

AGED; AGED, 80 AND OVER; CELL COUNT; DEMENTIA; FEMALE; HUMANS; INCLUSION BODIES; MALE; MIDDLE AGED; MOTOR NEURON DISEASE; PARKINSON DISEASE; REFERENCE VALUES; SPINAL CORD; SUBSTANTIA NIGRA; UBIQUITIN;

EID: 0036230412     PISSN: 03051846     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2990.2002.00384.x     Document Type: Article

References (45)

1. Involvement of the amygdala, dentate and hippocampus in motor neuron disease
2. Motor neuron disease with pallido-luysionigral atrophy
3. Substantia nigra degeneration in motor neuron disease: A quantitative study
4. Case-control study of amyotrophic lateral sclerosis
5. Motor neuron disease, parkinsonism and dementia. Report of a case with diffuse Lewy body-like intracytoplasmic inclusions
6. Amyotrophic lateral sclerosis, Porkinson's disease and Alzheimer's disease: Phylogenetic disorders of the human neocortex sharing many characteristics
7. Midbrain dopaminergic cell loss in Parkinson's disease: Computer visualization
8. Dementia, Parkinsonism and motor neuron disease: Neurochemical and neuropathological correlates
9. Concurrence of Alzheimer's disease, Parkinson's disease, diffuse Lewy body disease and amyotrophic lateral sclerosis
10. Amyotrophic lateral sclerosis and parkinsonism-dementia from Guam: Differences in neurofibrillary tangle distribution and density in the hippocampal formation and neocortex
11. Dementia and motor neuron disease: Morphometric, biochemical and Golgi studies
12. Amyotrophic lateral sclerosis and its association with dementia, Parkinsonism and other neurological disorders
13. Amyotrophic lateral sclerosis. Current issues in classification, pathogenesis and molecular pathology
14. Motor neurone disease-inclusion dementia
15. Ubiquitin-immunoreactive skein-like inclusions in the neostriatum are not restricted to amyotrophic lateral sclerosis, but are rather ageing-related structures
16. Ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis
17. Dementia accompanying motor neuron disease
18. New pathological findings in amyotrophic lateral sclerosis
19. Cell counts in the substantia nigra. A comparison of single section counts and disector counts in patients with Parkinson's disease and in controls
20. Sporadic amyotrophic lateral sclerosis with multiple system degeneration: A report of an autopsy case without respirator administration
21. Presenile dementia with motor neuron disease in Japan. Clinicopathological review of 26 cases
22. Presenile dementia with motor neuron disease
23. Amyotrophic lateral sclerosis with ophthalmoplegia and multisystem degeneration in patients on long-term use of respirators
24. Reappraisal of amyotrophic lateral sclerosis with dementia
25. Bunina bodies in neurons of the medullary reticular formation in a case of a myelotrophic lateral sclerosis
26. Frontotemporal dementia with motor neuron disease (amyotrophic lateral sclerosis with dementia)
27. Frontal lobe dementia in motor neuron disease
28. Ubiquitin-positive intraneuronal inclusions in the extra-motor cortices of presenile dementia patients with motor neuron disease
29. Oculomotor nuclear pathology in amyotrophic lateral sclerosis
30. Bunina bodies in amyotrophic lateral sclerosis immuno-stained with rabbit anti-crystatin C serum
31. Temporal lobe pathology in patients with amyotrophic lateral sclerosis
32. Amyotrophic lateral sclerosis of Guam: The nature of the neuropathological findings
33. Motor neuron disease with Parkinsonism
34. Studies on epidemiological, clinical and etiological aspects of Alz disease in Sardinia, Southern Italy
35. Semantic dementia with ubiquitin-positive tau-negative inclusion bodies
36. Sporadic amyotrophic lateral sclerosis with extensive neurological involvement
37. Ubiquitin in motor neuron disease. Study at the light and electron microscope
38. Nigral degeneration in a case of amyotrophic lateral sclerosis. Evidence of Lewy body-like and skein-like inclusions in the pigmented neurons
39. The intermedic lateral nucleus in sporadic amyotrophic lateral sclerosis
40. Frontal lobe dementia and motor neuron disease
41. Frontal lobe degeneration: Novel ubiquitin-immunoreactive neurites within the fronto-temporal cortex
42. Parkinsonism in motor neuron disease. Case report and literature review
43. Degeneration of the substantia nigra in familial amyotrophic lateral sclerosis
44. Clinical features of natural history of multiple system atrophy. An analysis of 100 cases
45. A clinicopathological study on 13 cases of motor neuron disease with dementia