Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity

Journal of Biological Chemistry

Volumn 277, Issue 39, 2002, Pages 36793-36798

  Niwa, Jun Ichi ^a,b,c   Ishigaki, Shinsuke ^a,b,c   Hishikawa, Nozomi ^a,b,c   Yamamoto, Masahiko ^a,b,c   Doyu, Manabu ^a,b,c   Murata, Shigeo ^a,b,c   Tanaka, Keiji ^a,b,c   Taniguchi, Naoyuki ^a,b,c   Sobue, Gen ^a,b,c  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; NEUROLOGY; PATHOLOGY; PROTEINS; TOXICITY;

MUTATIONS;

BIOCHEMISTRY;

DORFIN; PROTEASOME; PROTEIN; SUPEROXIDE DISMUTASE; UBIQUITIN; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CELL INCLUSION; CELL VIABILITY; CONTROLLED STUDY; CYTOPATHOLOGY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MOTONEURON; NERVE CELL; NEUROTOXICITY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN LOCALIZATION; PROTEIN STABILITY;

AGED; CELL LINE; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MUTATION; NEURONS; PLASMIDS; PROTEIN STRUCTURE, TERTIARY; SPINAL CORD; SUPEROXIDE DISMUTASE; TIME FACTORS; TRANSFECTION; UBIQUITIN;

EID: 0037184063     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M206559200     Document Type: Article

References (45)

1. Tyler, H. R., and Shefner, J. (1991) in Handbook of Clinical Neurology (Vinken P. J., Bruyn, G. W., and Klawans, H. L., eds) Vol. 59, pp. 169-215, Elsevier Science Publishers B. V., Amsterdam
2. Emery, A., and Holloway, S. (1982) in Human Motor Neuron Diseases (Rowland, L., ed), pp. 139-147, Raven Press, Ltd., New York
3. Rosen, D. R., Siddique, T., Patterson, D., Figlewicz, D. A., Sapp, P., Hentati, A., Donaldson, D., Goto, J., O'Regan, J. P., Deng, H. X., Rahmani, Z., Krizus, A., McKenna-Yasek, D., Cayabyab, A., Gaston, S. M., Berger, R., Tanzi, R. E., Halperin, J. J., Herzfeldt, B., Van den Bergh, R., Hung, W.-Y., Bird, T., Deng, G., Mulder, D. W., Smyth, C., Laing, N. G., Soriano, E., Pericak-Vance, M. A., Haines, J., Rouleau, G. A., Gusella, J. S., Horvitz, H. R., and Brown, R. H., Jr. (1993) Nature 362, 59-62
4. Julien, J. P. (2001) Cell 104, 581-591
5. Cleveland, D. W., and Rothstein, J. D. (2001) Nat. Rev. Neurosci. 2, 806-819
6. Newbery, H. J., and Abbott, C. M. (2002) Trends Mol. Med. 8, 88-92
7. Hirano, A. (1996) Neurology 47, S63-S66
8. Murayama S., Mori, H., Ihara, Y., Bouldin, T. W., Suzuki, K., and Tomonaga, M. (1990) Ann. Neurol. 27, 137-148
9. Leigh, P. N., Whitwell, H., Garofalo, O., Buller, J., Swash, M., Martin, J. E., Gallo, J. M., Weller, R. O., and Anderton, B. H. (1991) Brain 114, 775-788
10. Schiffer, D., Autilio-Gambetti, L., Chio, A., Gambetti, P., Giordana, M. T., Gullotta, F., Migheli, A., and Vigliani, M. C. (1991) J. Neuropathol. Exp. Neurol. 50, 463-473
11. Lowe, J. (1994) J. Neurol. Sci. 124, S38-S51
12. Kato, S., Takikawa, M., Nakashima, K., Hirano, A., Cleveland, D. W., Kusaka, H., Shibata, N., Kato, M., Nakano, L., and Ohama, E. (2000) Amyotroph. Lateral Scler. Other Motor Neuron Disord. 1, 163-184
13. Shibata, N., Hirano, A., Kobayashi, M., Siddique, T., Deng, H. X., Hung, W. Y., Kato, T., and Asayama, K. (1996) J. Neuropathol. Exp. Neurol. 55, 481-490
14. Niwa, J., Ishigaki, S., Doyu, M., Suzuki, T., Tanaka, K., and Sobue, G. (2001) Biochem. Biophys. Res. Commun. 281, 706-713
15. Morett, E., and Bork, P. (1999) Trends Biochem. Sci. 24, 229-231
16. Moynihan, T. P., Ardley, H. C., Nuber, U., Rose, S. A., Jones, P. F., Markham, A. F., Scheffner, M., and Robinson, P. A. (1999) J. Biol. Chem. 274, 30963-30968
17. Ardley, H. C., Tan, N. G., Rose, S. A., Markham, A. F., and Robinson, P. A. (2001) J. Biol. Chem. 276, 19640-19647
18. Kitada, T., Asakawa, S., Hattori, N., Matsumine, H., Yamamura, Y., Minoshima, S., Yokochi, M., Mizuno, Y., and Shimizu, N. (1998) Nature 392, 605-608
19. Shimura, H., Hattori, N., Kubo, S., Mizuno, Y., Asakawa, S., Minoshima, S., Shimizu, N., Iwai, K., Chiba, T., Tanaka, K., and Suzuki, T. (2000) Nat. Genet. 25, 302-305
20. Imai, Y., Soda, M., and Takahashi, R. (2000) J. Biol. Chem. 275, 35661-35664
21. Zhang, Y., Gao, J., Chung, K. K., Huang, H., Dawson, V. L., and Dawson, T. M. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 13354-13359
22. Joazeiro, C. A., Wing, S. S., Huang, H., Leverson, J. D., Hunter, T., and Liu, Y. C. (1999) Science 286, 309-312
23. Lorick, K. L., Jensen, J. P., Fang, S., Ong, A. M., Hatakeyama, S., and Weissman, A. M. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 11364-11369
24. Yang, Y., Fang, S., Jensen, J. P., Weissman, A. M., and Ashwell, J. D. (2000) Science 288, 874-877
25. Freemont, P. S. (2000) Curr. Biol. 10, R84-R87
26. Deshaies, R. J. (1999) Annu. Rev. Cell Dev. Biol. 15, 435-467
27. Joazeiro, C. A., and Weissman, A. M. (2000) Cell 102, 549-552
28. Jackson, P. K., Eldridge, A. G., Freed, E., Furstenthal, L., Hsu, J. Y., Kaiser, B. K., and Reimann, J. D. R. (2000) Trends Cell Biol. 10, 429-439
29. Johnston, J. A., Ward, C. L., and Kopito, R. R. (1998) J. Cell Biol. 143, 1883-1898
30. Johnston, J. A., Dalton, M. J., Gurney, M. E., and Kopito, R. R. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 12571-12576
31. Hishikawa, N., Hashizume, Y., Yoshida, M., and Sobue G. (2001) Neuropathol. Appl. Neurobiol. 27, 362-372
32. Borchelt, D. R., Lee, M. K., Slunt, H. S., Guarnieri, M., Xu, Z. S., Wong, P. C., Brown, R. H., Jr., Price, D. L., Sisodia, S. S., and Cleveland, D. W. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 8292-8296
33. Hoffman, E. K., Wilcox, H. M., Scott, R. W., and Siman, R. (1996) J. Neurol. Sci. 139, 15-20
34. Pasinelli, P., Borchelt, D. R., Houseweart, M. K., Cleveland, D. W., and Brown, R. H., Jr. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 15763-15768
35. Bruijn, L. I., Houseweart, M. K., Kato, S., Anderson, K. L., Anderson, S. D., Ohama, E., Reaume, A. G., Scott, R. W., and Cleveland, D. W. (1998) Science 281, 1851-1854
36. Durham, H. D., Roy, J., Dong, L., and Figlewicz D. A. (1997) J. Neuropathol. Exp. Neurol. 56, 523-530
37. Koide, T., Igarashi, S., Kikugawa, K., Nakano, R., Inuzuka, T., Yamada, M., Takahashi, H., and Tsuji, S. (1998) Neurosci. Lett. 257, 29-32
38. Tu, P. H., Raju, P., Robinson, K. A., Gurney, M. E., Trojanowski, J. Q., and Lee, V. M. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 3155-3160
39. Bruijn, L. I., Becher, M. W., Lee, M. K., Anderson, K. L., Jenkins, N. A., Copeland, N. G., Sisodia, S. S., Rothstein, J. D., Borchelt, D. R., Price, D. L., and Cleveland, D. W. (1997) Neuron 18, 327-338
40. Bence, N. F., Sampat, R. M., and Kopito, R. R. (2001) Science 292, 1552-1555
41. Shimura, H., Schlossmacher, M. G., Hattori, N., Frosch, M. P., Trockenbacher, A., Schneider, R., Mizuno, Y., Kosik, K. S., and Selkoe, D. J. (2001) Science 293, 263-269
42. Chung, K. K., Zhang, Y., Lim, K. L., Tanaka, Y., Huang, H., Gao, J., Ross, C. A., Dawson, V. L., and Dawson, T. M. (2001) Nat. Med. 7, 1144-1150
43. Bredesen, D. E., Ellerby, L. M., Hart, P. J., Wiedau-Pazos, M., and Valentine, J. S. (1997) Ann. Neurol. 42, 135-137
44. McClellan, A. J., and Frydman, J. (2001) Nat. Cell. Biol. 3, E51-E53
45. Murata, S., Minami, Y., Minami, M., Chiba, T., and Tanaka, K. (2001) EMBO Rep. 2, 1133-1138