17β-Estradiol reduces cortical lesion size in the glutamate excitotoxicity model by enhancing extracellular lactate: A new neuroprotective pathway

Brain Research

Volumn 901, Issue 1-2, 2001, Pages 230-236

  Mendelowitsch, Aminadav ^a,b   Ritz, Marie Françoise ^b   Ros, Jacqueline ^b   Langemann, Helen ^b   Gratzl, Otmar ^a  

^a Neurologische Universitatsklinik Basel   (Switzerland)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

17 Estradiol; Glutamate excitotoxicity; In vivo microdialysis; Lactate; Neuroprotection

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR; GLUTAMIC ACID; LACTIC ACID; NEUROPROTECTIVE AGENT; NEUROTOXIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFECT; ESTROGEN ACTIVITY; MALE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; BRAIN CORTEX; BRAIN INFARCTION; BRAIN INJURY; BRAIN ISCHEMIA; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; EXTRACELLULAR SPACE; METABOLISM; MICRODIALYSIS; NERVE CELL; NERVE DEGENERATION; PATHOPHYSIOLOGY; WISTAR RAT;

ANIMALS; BRAIN INJURIES; CEREBRAL CORTEX; CEREBRAL INFARCTION; DISEASE MODELS, ANIMAL; ESTRADIOL; EXTRACELLULAR SPACE; GLUTAMIC ACID; HYPOXIA-ISCHEMIA, BRAIN; LACTIC ACID; MALE; MICRODIALYSIS; NERVE DEGENERATION; NEURONS; NEUROPROTECTIVE AGENTS; NEUROTOXINS; RATS; RATS, WISTAR;

EID: 0035906427     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)02359-9     Document Type: Article

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