Expression of peripherin in ubiquinated inclusions of amyotrophic lateral sclerosis

Journal of the Neurological Sciences

Volumn 217, Issue 1, 2004, Pages 47-54

  He, Cui Zhen ^a   Hays, Arthur P ^a  

^a Columbia University ^*  (United States)

Author keywords

Amyotrophic lateral sclerosis; Intermediate filament protein; Lewy body like inclusion; Motor neuron disease; Peripherin; Skein like inclusion; Ubiquitin

Indexed keywords

ALPHA CRYSTALLIN; INTERMEDIATE FILAMENT PROTEIN; PARAFFIN; PERIPHERIN; UBIQUITIN;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; AUTOPSY; CELL INCLUSION; CONTROLLED STUDY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; IMMUNOREACTIVITY; LEWY BODY; MORPHOLOGY; MOTONEURON; PERIKARYON; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; SPINAL CORD; STAINING; TISSUE SECTION; VIDEORECORDING;

EID: 0348110609     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2003.08.016     Document Type: Article

References (49)

1. Beaulieu J.M., Nguyen M.D., Julien J.P. Late onset death of motor neurons in mice overexpressing wild-type peripherin. J. Cell Biol. 147(3):1999;531-544.
2. Al-Chalabi A., Leigh P.N. Recent advances in amyotrophic lateral sclerosis. Curr. Opin. Neurol. 13(4):2000;397-405.
3. Rowland L.P., Shneider N.A. Amyotrophic lateral sclerosis. N. Engl. J. Med. 344(22):2001;1688-1700.
4. Brown R.H. Jr. Superoxide dismutase in familial amyotrophic lateral sclerosis: models for gain of function. Curr. Opin. Neurobiol. 5(6):1995;841-846.
5. Johnston J.A., Dalton M.J., Gurney M.E., Kopito R.R. Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. U. S. A. 97(23):2000;12571-12576.
6. Stieber A., Gonatas J.O., Gonatas N.K. Aggregation of ubiquitin and a mutant ALS-linked SOD1 protein correlate with disease progression and fragmentation of the Golgi apparatus. J. Neurol. Sci. 173(1):2000;53-62.
7. Cleveland D.W., Liu J. Oxidation versus aggregation - how do SOD1 mutants cause ALS? Nat. Med. 6(12):2000;1320-1321.
8. Julien J.P. Amyotrophic lateral sclerosis. Unfolding the toxicity of the misfolded. Cell. 104(4):2001;581-591.
9. Bergmann M. Motor neuron disease/amyotrophic lateral sclerosis - lessons from ubiquitin. Pathol. Res. Pract. 189(8):1993;902-912.
10. Leigh P.N., Anderton B.H., Dodson A., Gallo J.M., Swash M., Power D.M. Ubiquitin deposits in anterior horn cells in motor neurone disease. Neurosci. Lett. 93(2-3):1988;197-203.
11. Leigh P.N., Whitwell H., Garofalo O., Buller J., Swash M., Martin J.E.et al. Ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis. Morphology, distribution, and specificity. Brain. 114(Pt 2):1991;775-788.
12. Lowe J., Lennox G., Jefferson D., Morrell K., McQuire D., Gray T.et al. A filamentous inclusion body within anterior horn neurones in motor neurone disease defined by immunocytochemical localisation of ubiquitin. Neurosci. Lett. 94(1-2):1988;203-210.
13. Leung D.K., Hays A., Karlikaya G., Del Bene M.L., Rowland L.P. Diagnosis of ALS: clinicopathologic analysis of 76 autopsies. Neurology. 52(Suppl. 2):1999;A164.
14. Kato T., Katagiri T., Hirano A., Kawanami T., Sasaki H. Lewy body-like hyaline inclusions in sporadic motor neuron disease are ubiquitinated. Acta Neuropathol. 77(4):1989;391-396.
15. Dickson D.W. Tau and synuclein and their role in neuropathology. Brain Pathol. 9(4):1999;657-661.
16. Shibata N., Hirano A., Kobayashi M., Sasaki S., Kato T., Matsumoto S.et al. Cu/Zn superoxide dismutase-like immunoreactivity in Lewy body-like inclusions of sporadic amyotrophic lateral sclerosis. Neurosci. Lett. 179(1-2):1994;149-152.
17. Kato S., Takikawa M., Nakashima K., Hirano A., Cleveland D.W., Kusaka H.et al. New consensus research on neuropathological aspects of familial amyotrophic lateral sclerosis with superoxide dismutase 1 (SOD1) gene mutations: inclusions containing SOD1 in neurons and astrocytes. Amyotroph. Lateral Scler. Other Mot. Neuron Disord. 1(3):2000;163-184.
18. Munoz D.G., Greene C., Perl D.P., Selkoe D.J. Accumulation of phosphorylated neurofilaments in anterior horn motoneurons of amyotrophic lateral sclerosis patients. J. Neuropathol. Exp. Neurol. 47(1):1988;9-18.
19. Schmidt M.L., Carden M.J., Lee V.M., Trojanowski J.Q. Phosphate dependent and independent neurofilament epitopes in the axonal swellings of patients with motor neuron disease and controls. Lab. Invest. 56(3):1987;282-294.
20. Sasaki S., Maruyama S. Immunocytochemical and ultrastructural studies of hyaline inclusions in sporadic motor neuron disease. Acta Neuropathol. 82(4):1991;295-301.
21. Wong N.K., He B.P., Strong M.J. Characterization of neuronal intermediate filament protein expression in cervical spinal motor neurons in sporadic amyotrophic lateral sclerosis (ALS). J. Neuropathol. Exp. Neurol. 59(11):2000;972-982.
22. Leonard D.G., Gorham J.D., Cole P., Greene L.A., Ziff E.B. A nerve growth factor-regulated messenger RNA encodes a new intermediate filament protein. J. Cell Biol. 106(1):1988;181-193.
23. Escurat M., Gumpel M., Lachapelle F., Gros F., Portier M.M. Comparative expression of 2 intermediate filament proteins, peripherin and the 68 kDa neurofilament protein, during embryonal development of the rat. C. R. Acad. Sci. III. 306(14):1988;447-456.
24. Parysek L.M., Goldman R.D. Distribution of a novel 57 kDa intermediate filament (IF) protein in the nervous system. J. Neurosci. 8(2):1988;555-563.
25. Troy C.M., Brown K., Greene L.A., Shelanski M.L. Ontogeny of the neuronal intermediate filament protein, peripherin, in the mouse embryo. Neuroscience. 36(1):1990;217-237.
26. Corbo M., Hays A.P. Peripherin and neurofilament protein coexist in spinal spheroids of motor neuron disease. J. Neuropathol. Exp. Neurol. 51(5):1992;531-537.
27. Foley J., Ley C.A., Parysek L.M. The structure of the human peripherin gene (PRPH) and identification of potential regulatory elements. Genomics. 22(2):1994;456-461.
28. Ince P.G., Tomkins J., Slade J.Y., Thatcher N.M., Shaw P.J. Amyotrophic lateral sclerosis associated with genetic abnormalities in the gene encoding Cu/Zn superoxide dismutase: molecular pathology of five new cases, and comparison with previous reports and 73 sporadic cases of ALS. J. Neuropathol. Exp. Neurol. 57(10):1998;895-904.
29. Chou S.M. Pathognomony of intraneuronal inclusions in ALS. 1979;Univ. Park Press, Baltimore.
30. Murayama S., Mori H., Ihara Y., Bouldin T.W., Suzuki K., Tomonaga M. Immunocytochemical and ultrastructural studies of lower motor neurons in amyotrophic lateral sclerosis. Ann. Neurol. 27(2):1990;137-148.
31. Mizusawa H., Nakamura H., Wakayama I., Yen S.H., Hirano A. Skein-like inclusions in the anterior horn cells in motor neuron disease. J. Neurol. Sci. 105(1):1991;14-21.
32. Duffy P.E.T., Tennyson V.M. Phase and electron microscopic observations of Lewy bodies and melanin granules in the substantia nigra and locus coeruleus in Parkinson's disease. J. Neuropathol. Exp. Neurol. 24:1965;398-414.
33. Trojanowski J.Q., Lee V.M. Aggregation of neurofilament and alpha-synuclein proteins in Lewy bodies: implications for the pathogenesis of Parkinson disease and Lewy body dementia. Arch. Neurol. 55(2):1998;151-152.
34. Su M., Yoshida Y., Ishiguro H., Hirota K. Nigral degeneration in a case of amyotrophic lateral sclerosis: evidence of Lewy body-like and skein-like inclusions in the pigmented neurons. Clin. Neuropathol. 18(6):1999;293-300.
35. Hirano A., Donnenfeld H., Sasaki S., Nakano I. Fine structural observations of neurofilamentous changes in amyotrophic lateral sclerosis. J. Neuropathol. Exp. Neurol. 43(5):1984;461-470.
36. Julien J.P., Beaulieu J.M. Cytoskeletal abnormalities in amyotrophic lateral sclerosis: beneficial or detrimental effects? J. Neurol. Sci. 180(1-2):2000;7-14.
37. Robertson J., Doroudchi M.M., Nguyen M.D., Durham H.D., Strong M.J., Shaw G.et al. A neurotoxic peripherin splice variant in a mouse model of ALS. J. Cell Biol. 160(6):2003;939-949.
38. Rouleau G.A., Clark A.W., Rooke K., Pramatarova A., Krizus A., Suchowersky O.et al. SOD1 mutation is associated with accumulation of neurofilaments in amyotrophic lateral sclerosis. Ann. Neurol. 39(1):1996;128-131.
39. Parry D.A., Steinert P.M. Intermediate filaments: molecular architecture, assembly, dynamics and polymorphism. Q. Rev. Biophys. 32(2):1999;99-187.
40. Leung C.L., Green K.J., Liem R.K. Plakins: a family of versatile cytolinker proteins. Trends Cell Biol. 12(1):2002;37-45.
41. Head M.W., Goldman J.E. Small heat shock proteins, the cytoskeleton, and inclusion body formation. Neuropathol. Appl. Neurobiol. 26(4):2000;304-312.
42. Brenner M., Johnson A.B., Boespflug-Tanguy O., Rodriguez D., Goldman J.E., Messing A. Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease. Nat. Genet. 27(1):2001;117-120.
43. Dalakas M.C., Park K.Y., Semino-Mora C., Lee H.S., Sivakumar K., Goldfarb L.G. Desmin myopathy, a skeletal myopathy with cardiomyopathy caused by mutations in the desmin gene. N. Engl. J. Med. 342(11):2000;770-780.
44. Troy C.M., Muma N.A., Greene L.A., Price D.L., Shelanski M.L. Regulation of peripherin and neurofilament expression in regenerating rat motor neurons. Brain Res. 529(1-2):1990;232-238.
45. Beaulieu J.M., Kriz J., Julien J.P. Induction of peripherin expression in subsets of brain neurons after lesion injury or cerebral ischemia. Brain Res. 946(2):2002;153-161.
46. Beaulieu J.M., Robertson J., Julien J.P. Interactions between peripherin and neurofilaments in cultured cells: disruption of peripherin assembly by the NF-M and NF-H subunits. Biochem. Cell. Biol. 77(1):1999;41-45.
47. Ho C.L., Chien C.L., Brown K., Liem R.K. Ultrastructural studies of carboxyl-terminal truncation mutants of the neuronal intermediate filament protein peripherin. J. Neurochem. 70(5):1998;1916-1924.
48. Landon F., Wolff A., de Nechaud B. Mouse peripherin isoforms. Biol. Cell. 92(6):2000;397-407.
49. Bence N.F., Sampat R.M., Kopito R.R. Impairment of the ubiquitin-proteasome system by protein aggregation. Science. 292(5521):2001;1552-1555.