Immune system alterations in sporadic amyotrophic lateral sclerosis patients suggest an ongoing neuroinflammatory process

Journal of Neuroimmunology

Volumn 210, Issue 1-2, 2009, Pages 73-79

  Mantovani, Stefania ^a,b   Garbelli, Silvia ^a,b   Pasini, Alessandra ^a   Alimonti, Dario ^a,c   Perotti, Cesare ^d   Melazzini, Mario ^a,e   Bendotti, Caterina ^a,f   Mora, Gabriele ^a  

^a IRCCS   (Italy)

^b ISPESL   (Italy)

^c OSPEDALI RIUNITI   (Italy)

^d FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^e AISLA Onlus   (Italy)

^f MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

Amyotrophic lateral sclerosis (ALS); Immunologic alteration; Motor neuron disease; Regulatory T cell; T lymphocyte

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CHEMOKINE RECEPTOR CCR2; HLA DR ANTIGEN;

ADAPTIVE IMMUNITY; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BRAIN REGION; CD4+ CD25+ T LYMPHOCYTE; CENTRAL NERVOUS SYSTEM; HLA SYSTEM; HUMAN; IMMUNE SYSTEM; MICROGLIA; MONOCYTE; NERVE DEGENERATION; NERVOUS SYSTEM INFLAMMATION; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE;

ADULT; AMYOTROPHIC LATERAL SCLEROSIS; ANTIGENS, SURFACE; APOPTOSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; DOWN-REGULATION; FEMALE; HLA-DR ANTIGENS; HUMANS; LYMPHOCYTE ACTIVATION; MALE; MICROGLIA; MIDDLE AGED; MONOCYTES; MYELITIS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, CCR2; T-LYMPHOCYTES, REGULATORY; UP-REGULATION;

EID: 67349139435     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2009.02.012     Document Type: Article

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