Identification of Potential Mechanisms for Regulation of p115 RhoGEF through Analysis of Endogenous and Mutant Forms of the Exchange Factor

Journal of Biological Chemistry

Volumn 276, Issue 31, 2001, Pages 28897-28905

  Wells, Clark D ^a   Gutowski, Stephen ^a   Bollag, Gideon ^b   Sternweis, Paul C ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b ONYX PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOLOGICAL MEMBRANES; CELLS; CHEMICAL ACTIVATION; ENZYMES; IMMUNOLOGY;

MUTANTS;

BIOCHEMISTRY;

AMINO ACID; ENZYME; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE; LYSOPHOSPHATIDIC ACID; PLECKSTRIN; PROTEIN; PROTEIN P115 RHOGEF; RHO FACTOR; SPHINGOSINE 1 PHOSPHATE; UNCLASSIFIED DRUG; DRUG DERIVATIVE; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE TRIPHOSPHATE; HYBRID PROTEIN; LYSOPHOSPHOLIPID; RECOMBINANT PROTEIN; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR P115; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CYTOSOL; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; ARMYWORM; BACULOVIRUS; BINDING SITE; CELL LINE; CELL STRAIN 3T3; CHEMISTRY; GENE DELETION; GENETIC TRANSFECTION; GENETICS; KINETICS; METABOLISM; MOUSE; SRC HOMOLOGY DOMAIN;

ANIMALIA;

3T3 CELLS; ANIMALS; BACULOVIRIDAE; BINDING SITES; CELL LINE; CELL MEMBRANE; GUANINE NUCLEOTIDE EXCHANGE FACTORS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); GUANOSINE TRIPHOSPHATE; HUMANS; KINETICS; LYSOPHOSPHOLIPIDS; MICE; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; RHOA GTP-BINDING PROTEIN; SEQUENCE DELETION; SPHINGOSINE; SPODOPTERA; SRC HOMOLOGY DOMAINS; TRANSFECTION;

EID: 0035800854     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M102913200     Document Type: Article

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