Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor

Journal of Biological Chemistry

Volumn 279, Issue 45, 2004, Pages 47352-47362

  Kristelly, Romana ^a   Gao, Guang ^a   Tesmer, John J G ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONS; CRYSTAL ATOMIC STRUCTURE; CRYSTALS; GENES;

GENE TRANSCRIPTION; HOMOLOGY; PROTEIN DOCKING SITE;

PROTEINS;

LEUKEMIA ASSOCIATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; PLECKSTRIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; COMPLEX FORMATION; CONFORMATION; CRYSTAL STRUCTURE; FLUORESCENCE RESONANCE ENERGY TRANSFER; IN VITRO STUDY; MUTATIONAL ANALYSIS; NUCLEOTIDE TRANSPORT; PRIORITY JOURNAL; PROTEIN DOMAIN; STRUCTURAL HOMOLOGY;

AMINO ACID SEQUENCE; BINDING SITES; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; DNA; FLUORESCENCE RESONANCE ENERGY TRANSFER; GTP PHOSPHOHYDROLASES; GUANINE NUCLEOTIDE EXCHANGE FACTORS; GUANOSINE DIPHOSPHATE; HUMANS; HYDROGEN BONDING; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; NUCLEOTIDES; PEPTIDE ELONGATION FACTOR TU; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RHOA GTP-BINDING PROTEIN; SEQUENCE HOMOLOGY, AMINO ACID; TIME FACTORS;

EID: 8744317101     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M406056200     Document Type: Article

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