Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoGEF

Protein Science

Volumn 20, Issue 1, 2011, Pages 107-117

  Chen, Zhe ^a   Guo, Liang ^b   Sprang, Stephen R ^c   Sternweis, Paul C ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b ARGONNE NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF MONTANA   (United States)

Author keywords

DH; G12; G13; GTP binding protein alpha subunits; Guanine nucleotide exchange factors; PH; RGS proteins; Rho GTPase

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; P115 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; AUTOREGULATION; CRYSTAL STRUCTURE; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY;

AMINO ACID MOTIFS; CRYSTALLOGRAPHY, X-RAY; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; PROTEIN STRUCTURE, TERTIARY; SCATTERING, SMALL ANGLE; STRUCTURE-ACTIVITY RELATIONSHIP; X-RAY DIFFRACTION;

EID: 78650777435     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.542     Document Type: Article

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