Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: Evidence for its fusion with MLL in acute myeloid leukemia

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 5, 2000, Pages 2145-2150

  Kourlas, Peter J ^a   Strout, Matthew P ^a   Becknell, Brian ^a   Veronese, Maria Luisa ^b   Croce, Carlo M ^b   Theil, Karl S ^a   Krahe, Ralf ^a   Ruutu, Tapani ^c   Knuutila, Sakari ^c   Bloomfield, Clara D ^a   Caligiuri, Michael A ^a  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Dbl protein; Gene rearrangements; LARG

Indexed keywords

DNA; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MESSENGER RNA;

ACUTE GRANULOCYTIC LEUKEMIA; AGED; AMINO ACID SEQUENCE; ARTICLE; CASE REPORT; CENTROMERE; CHROMOSOME 11Q; CHROMOSOME ANALYSIS; CHROMOSOME DELETION; FLUORESCENCE IN SITU HYBRIDIZATION; GENE FUSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; KARYOTYPE; MALE; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TELOMERE;

ADULT; AMINO ACID SEQUENCE; ARTIFICIAL GENE FUSION; BASE SEQUENCE; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 11; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; LEUKEMIA, MYELOMONOCYTIC, ACUTE; MALE; MOLECULAR SEQUENCE DATA; MYELOID-LYMPHOID LEUKEMIA PROTEIN; PROTO-ONCOGENES; TRANSCRIPTION FACTORS;

EID: 12944262403     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.040569197     Document Type: Article

References (64)

1. Look, A. T. (1997) Science 278, 1059-1064.
2. Rabbitts, T. H. (1994) Nature (London) 372, 143-149.
3. Cimino, G., Moir, D. T., Canaani, O., Williams, K., Crist, W. M., Katzav, S., Cannizzaro, L., Lange, B., Nowell, P. C., Croce, C. M. & Canaani. E. (1991) Cancer Res. 51, 6712-6714.
4. Djabali, M., Selleri, L., Parry, P., Bower, M., Young, B. D. & Evans, G. A. (1992) Nat. Genet. 2, 113-118.
5. Tkachuk, D. C., Kohler, S. & Cleary, M. L. (1992) Cell 71, 691-700.
6. Ziemin-van der Poel, S., McCabe, N. R., Gill, H. J., Espinosa, R., III, Patel, Y., Harden, A., Rubinelli, P., Smith, S. D., LeBeau, M. M., Rowley, J. D. & Diaz, M. O. (1991) Proc. Natl. Acad. Sci. USA 88, 10735-10739.
7. Pui, C. H., Relling, M. V., Rivera, G. K., Hancock, M. L., Raimondi, S. C., Heslop, H. E., Santana, V. M., Ribeiro, R. C., Sandlund, J. T., Mahmoud, H. H., et al. (1995) Leukemia 9, 1990-1996.
8. Smith, M. A., McCaffrey, R. P. & Karp, J. E. (1996) J. Natl. Cancer Inst. 88, 407-408.
9. Nilson, I., Lochner, K., Siegler, G., Greil, J., Beck, J. D., Fey, G. H. & Marschalek, R. (1996) Br. J. Haematol. 93, 966-972.
10. Rasio, D., Schichman, S. A., Negrini, M., Canaani, E. & Croce, C. M. (1996) Cancer Res. 56, 1766-1769.
11. Gu, Y., Alder, H., Nakamura, T., Schichman, S. A., Prasad, R., Canaani, O., Saito, H., Croce, C. M. & Canaani, E. (1994) Cancer Res. 54, 2326-2330.
12. Ida, K., Kitabayashi, I., Taki, T., Taniwaki, M., Noro, K., Yamamoto, M., Ohki, M. & Hayashi, Y. (1997) Blood 90, 4699-4704.
13. Rubnitz, J. E., Behm, F. G. & Downing, J. R. (1996) Leukemia 10, 74-82.
14. Taki, T., Sako, M., Tsuchida, M. & Hayashi, Y. (1997) Blood 89, 3945-3950.
15. Taki, T., Shibuya, N., Taniwaki, M., Hanada, R., Morishita, K., Bessho, F., Yanagisawa, M. & Hayashi, Y. (1998) Blood 92, 1125-1130.
16. Thirman, M. J., Levitan, D. A., Kobayashi, H., Simon, M. C. & Rowley, J. D. (1994) Proc. Natl. Acad. Sci. USA 91, 12110-12114.
17. So, C. W., Caldas, C., Liu, M. M., Chen, S. J., Huang, Q. H., Gu, L. J., Sham, M. H., Wiedemann, L. M. & Chan, L. C. (1997) Proc. Natl. Acad. Sci. USA 94, 2563-2568.
18. Sobulo, O. M., Borrow, J., Tomek, R., Reshmi, S., Harden, A., Schlegelberger, B., Housman, D., Doggett, N. A., Rowley, J. D. & Zeleznik-Le, N. J. (1997) Proc. Natl. Acad. Sci. USA 94, 8732-8737.
19. Osaka, M., Rowley, J. D. & Zeleznik-Le, N. J. (1999) Proc. Natl. Acad. Sci. USA 96, 6428-6433.
20. Megonigal, M. D., Rappaport, E. F., Jones, D. H., Williams, T. M., Lovett, B. D., Kelly, K. M., Lerou, P. H., Moulton, T., Budarf, M. L. & Felix, C. A. (1998) Proc. Natl. Acad. Sci. USA 95, 6413-6418.
21. Hillion, J., Le Coniat, M., Jonveaux, P., Berger, R. & Bernard, O. A. (1997) Blood 90, 3714-3719.
22. Taki, T., Kano, H., Taniwaki, M., Sako, M., Yanagisawa, M. & Hayashi, Y. (1999) Proc. Natl. Acad. Sci. USA 96, 14535-14540.
23. Taki, T., Ohnishi, H., Shinohara, K., Sako, M., Bessho, F., Yanagisawa, M. & Hayashi, Y. (1999) Cancer Res. 59, 4261-4265.
24. Thirman, M. J., Gill, H. J., Burnett, R. C., Mbangkollo, D., McCabe, N. R., Kobayashi, H., Ziemin-van der Poel, S., Kaneko, Y., Morgan, R., Sandberg, A. A., et al. (1993) N. Engl. J. Med. 329, 909-914.
25. Secker-Walker, L. M. (1998) Leukemia 12, 776-778.
26. Caligiuri, M. A., Strout, M. P., Schichman, S. A., Mrózek, K., Arthur, D. C., Herzig, G. P., Baer, M. R., Schiffer, C. A., Heinonen, K., Knuutila, S., et al. (1996) Cancer Res. 56, 1418-1425.
27. Caligiuri, M. A., Strout, M. P., Lawrence, D., Arthur, D. C., Baer, M. R., Yu, F., Knuutila, S., Mrózek, K., Oberkircher, A. R., Marcucci, G., et al. (1998) Cancer Res. 58, 55-59.
28. Schichman, S. A., Caligiuri, M. A., Gu, Y., Strout, M. P., Canaani, E., Bloomfield, C. D. & Croce, C. M. (1994) Proc. Natl. Acad. Sci. USA 91, 6236-6239.
29. Kobayashi, H., Espinosa, R., 3rd, Fernald, A. A., Begy, C., Diaz, M. O., Le Beau, M. M. & Rowley, J. D. (1993) Genes Chromosomes Cancer 8, 246-252.
30. Harbott, J., Mancini, M., Verellen-Dumoulin, C., Moorman, A. V. & Secker-Walker, L. M. (1998) Leukemia 12, 823-827.
31. Raimondi, S. C., Frestedt, J. L., Pui, C. H., Downing, J. R., Head, D. R., Kersey, J. H. & Behm, F. G. (1995) Blood 86, 1881-1886.
32. Cimino, G., Nakamura, T., Gu, Y., Canaani, O., Prasad, R., Crist, W. M., Carroll, A. J., Baer, M., Bloomfield, C. D., Nowell, P. C., et al. (1992) Cancer Res. 52, 3811-3813.
33. Cherif, D., Bernard, O., Paulien, S., James, M. R., Le Paslier, D. & Berger, R. (1994) Leukemia 8, 578-586.
34. Strout, M. P., Mrozek, K., Heinonen, K., Sait, S. N., Shows, T. B. & Aplan, P. D. (1996) Genes Chromosomes Cancer 16, 204-210.
35. Caligiuri, M. A., Schichman, S. A., Strout, M. P., Mrózek, K., Baer, M. R., Frankel, S. R., Barcos, M., Herzig, G. P., Croce, C. M. & Bloomfield, C. D. (1994) Cancer Res. 54, 370-373.
36. Mitelman, F. (1995) ISCN: An International System for Human Cytogenetic Nomenclature (Karger, Basel).
37. Lichter, P., Cremer, T., Borden, J., Manuelidis, L. & Ward, D. C. (1988) Hum. Genet. 80, 224-234.
38. Pinkel, D., Straume, T. & Gray, J. W. (1986) Proc. Natl. Acad. Sci. USA 83, 2934-2938.
39. Kallioniemi, A., Kallioniemi, O. P., Sudar, D., Rutovitz, D., Gray, J. W., Waldman, F. & Pinkel, D. (1992) Science 258, 818-821.
40. Monni, O., Joensuu, H., Franssila, K. & Knuutila, S. (1996) Blood 87, 5269-5278.
41. Gustincich, S., Manfioletti, G., Del Sal, G. & Schneider, C. (1991) BioTechniques 11, 298-301.
42. Gu, Y., Nakamura, T., Alder, H., Prasad, R., Canaani, O., Cimino, G., Croce, C. M. & Canaani, E. (1992) Cell 71, 701-708.
43. Sambrook, J., Fritsch, E. & Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual (Cold Spring Harbor Lab. Press, Plainview, NY).
44. Hofmann, K., Bucher, P., Falquet, L. & Bairoch, A. (1999) Nucleic Acids Res. 27, 215-219.
45. Deloukas, P., Schuler, G. D., Gyapay, G., Beasley, E. M., Soderlund, C., Rodriguez-Tome, P., Hui, L., Matise, T. C., McKusick, K. B., Beckmann, J. S., et al. (1998) Science 282, 744-746.
46. Nagase, T., Ishikawa, K., Nakajima, D., Ohira, M., Seki, N., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N. & Ohara, O. (1997) DNA Res. 4, 141-150.
47. Super, H. G., Strissel, P. L., Sobulo, O. M., Burian, D., Reshmi, S. C., Roe, B., Zeleznik-Le, N. J., Diaz, M. O. & Rowley, J. D. (1997) Genes Chromosomes Cancer 20, 185-195.
48. Seasholtz, T. M., Majumdar, M. & Brown, J. H. (1999) Mol. Pharmacol. 55, 949-956.
49. Fukuhara, S., Murga, C., Zohar, M., Igishi, T. & Gutkind, J. S. (1999) J. Biol. Chem. 274, 5868-5879.
50. Whitehead, I. P., Campbell, S., Rossman, K. L. & Der, C. J. (1997) Biochim. Biophys. Acta 1332, F1-F23.
51. Olson, M. F. (1996) J. Mol. Med. 74, 563-571.
52. Hall, A. (1998) Science 279, 509-514.
53. Hart, M. J., Eva, A., Zangrilli, D., Aaronson, S. A., Evans, T., Cerione, R. A. & Zheng, Y. (1994) J. Biol. Chem. 269, 62-65.
54. Shaw, G. (1996) BioEssays 18, 35-46.
55. Fanning, A. S. & Anderson, J. M. (1999) Curr. Opin. Cell. Biol. 11, 432-439.
56. Gorlich, D. (1997) Curr. Opin. Cell. Biol. 9, 412-419.
57. Yoneda, Y. (1997) J. Biochem. (Tokyo) 121, 811-817.
58. Hart, M. J., Jiang, X., Kozasa, T., Roscoe, W., Singer, W. D., Gilman, A. G., Sternweis, P. C. & Bollag, G. (1998) Science 280, 2112-2114.
59. Van Aelst, L. & D'Souza-Schorey, C. (1997) Genes Dev. 11, 2295-2322.
60. Faderl, S., Talpaz, M., Estrov, Z., O'Brien, S., Kurzrock, R. & Kantarjian, H. M. (1999) N. Engl. J. Med. 341, 164-172.
61. Tanaka, K., Arif, M., Eguchi, M., Kyo, T., Dohy, H. & Kamada, N. (1997) Blood 89, 596-600.
62. Johansson, B., Moorman, A. V. & Secker-Walker, L. M. (1998) Leukemia 12, 828-833.
63. Hart, M. J., Sharma, S., elMasry, N., Qiu, R. G., McCabe, P., Polakis, P. & Bollag, G. (1996) J. Biol. Chem. 271, 25452-25458.
64. Strout, M. P., Marcucci, G., Caligiuri, M. A. & Bloomfield, C. D. (1999) Ann. Hematol. 78, 251-264.