Binding of PDZ-RhoGEF to ATP-binding cassette transporter A1 (ABCA1) induces cholesterol efflux through RhoA activation and prevention of transporter degradation

Journal of Biological Chemistry

Volumn 285, Issue 21, 2010, Pages 16369-16377

  Okuhira, Keiichiro ^a   Fitzgerald, Michael L ^b   Tamehiro, Norimasa ^b   Ohoka, Nobumichi ^a   Suzuki, Kazuhiro ^a   Sawada, Jun Ichi ^a   Naito, Mikihiko ^a   Nishimaki Mogami, Tomoko ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A-1; ATP-BINDING CASSETTE TRANSPORTERS; C TERMINUS; CHOLESTEROL EFFLUX; CONSTITUTIVELY ACTIVES; DOMINANT NEGATIVE; FUNCTIONAL INTERACTION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HIGH DENSITY LIPOPROTEIN; LIPID EFFLUX; PHARMACOLOGICAL INHIBITION; PROTEIN DEGRADATION; PROTEIN LEVEL; RNA INTERFERENCE; TRANSCRIPTIONAL REGULATION;

CELL CULTURE; CHEMICAL ACTIVATION; CHOLESTEROL; DEGRADATION; RNA; STABILIZATION;

PROTEINS;

ABC TRANSPORTER A1; APOLIPOPROTEIN A1; CHOLESTEROL; PDZ PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 11; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; MUTANT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION;

APOLIPOPROTEIN A-I; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CELL LINE; CHOLESTEROL; FIBROBLASTS; GENES, DOMINANT; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; LIPOPROTEINS, HDL; MUTATION; PDZ DOMAINS; PPAR GAMMA; PROTEIN STABILITY; RHOA GTP-BINDING PROTEIN;

EID: 77952338862     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.061424     Document Type: Article

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