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Volumn 91, Issue 1, 2012, Pages 47-57

Mobilization of hematopoietic stem and leukemia cells

Author keywords

CXCR4; Integrins; Niche; Plerixafor AMD3100; Stromal derived factor 1 CXCL12

Indexed keywords

CHEMOKINE RECEPTOR CXCR4;

EID: 84855337388     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0210085     Document Type: Review
Times cited : (29)

References (140)
  • 1
    • 0000062301 scopus 로고
    • Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells
    • Becker, A. J., McCulloch, E. A., Till, J. E. (1963) Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells. Nature 197, 452-454.
    • (1963) Nature , vol.197 , pp. 452-454
    • Becker, A.J.1    McCulloch, E.A.2    Till, J.E.3
  • 2
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • Bonnet, D., Dick, J. E. (1997) Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat. Med. 3, 730-737.
    • (1997) Nat. Med , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 3
    • 58149380742 scopus 로고    scopus 로고
    • Stem cell concepts renew cancer research
    • Dick, J. E. (2008) Stem cell concepts renew cancer research. Blood 112, 4793-4807.
    • (2008) Blood , vol.112 , pp. 4793-4807
    • Dick, J.E.1
  • 4
    • 3142620882 scopus 로고    scopus 로고
    • Relation between CXCR-4 expression, Flt3 mutations, and unfavorable prognosis of adult acute myeloid leukemia
    • Rombouts, E. J., Pavic, B., Lowenberg, B., Ploemacher, R. E. (2004) Relation between CXCR-4 expression, Flt3 mutations, and unfavorable prognosis of adult acute myeloid leukemia. Blood 104, 550-557.
    • (2004) Blood , vol.104 , pp. 550-557
    • Rombouts, E.J.1    Pavic, B.2    Lowenberg, B.3    Ploemacher, R.E.4
  • 5
    • 33846241600 scopus 로고    scopus 로고
    • CXCR4 is a prognostic marker in acute myelogenous leukemia
    • Spoo, A. C., Lubbert, M., Wierda, W. G., Burger, J. A. (2007) CXCR4 is a prognostic marker in acute myelogenous leukemia. Blood 109, 786-791.
    • (2007) Blood , vol.109 , pp. 786-791
    • Spoo, A.C.1    Lubbert, M.2    Wierda, W.G.3    Burger, J.A.4
  • 7
    • 67649920749 scopus 로고    scopus 로고
    • Growth factors, matrices, and forces combine and control stem cells
    • Discher, D. E., Mooney, D. J., Zandstra, P. W. (2009) Growth factors, matrices, and forces combine and control stem cells. Science 324, 1673-1677.
    • (2009) Science , vol.324 , pp. 1673-1677
    • Discher, D.E.1    Mooney, D.J.2    Zandstra, P.W.3
  • 8
    • 21244463426 scopus 로고    scopus 로고
    • SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
    • Kiel, M. J., Yilmaz, O. H., Iwashita, T., Terhorst, C., Morrison, S. J. (2005) SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121, 1109-1121.
    • (2005) Cell , vol.121 , pp. 1109-1121
    • Kiel, M.J.1    Yilmaz, O.H.2    Iwashita, T.3    Terhorst, C.4    Morrison, S.J.5
  • 9
    • 41149109622 scopus 로고    scopus 로고
    • Uncertainty in the niches that maintain haematopoietic stem cells
    • Kiel, M. J., Morrison, S. J. (2008) Uncertainty in the niches that maintain haematopoietic stem cells. Nat. Rev. Immunol. 8, 290-301.
    • (2008) Nat. Rev. Immunol , vol.8 , pp. 290-301
    • Kiel, M.J.1    Morrison, S.J.2
  • 12
    • 33646435309 scopus 로고    scopus 로고
    • The stem cell niches in bone
    • Yin, T., Li, L. (2006) The stem cell niches in bone. J. Clin. Invest. 116, 1195-1201.
    • (2006) J. Clin. Invest , vol.116 , pp. 1195-1201
    • Yin, T.1    Li, L.2
  • 17
    • 0032532361 scopus 로고    scopus 로고
    • Cell cycle-related changes in repopulating capacity of human mobilized peripheral blood CD34(+) cells in non-obese diabetic/severe combined immune-deficient mice
    • Gothot, A., van der Loo, J. C., Clapp, D. W., Srour, E. F. (1998) Cell cycle-related changes in repopulating capacity of human mobilized peripheral blood CD34(+) cells in non-obese diabetic/severe combined immune-deficient mice. Blood 92, 2641-2649.
    • (1998) Blood , vol.92 , pp. 2641-2649
    • Gothot, A.1    van der Loo, J.C.2    Clapp, D.W.3    Srour, E.F.4
  • 18
    • 28544436371 scopus 로고    scopus 로고
    • Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates
    • Passegué, E., Wagers, A. J., Giuriato, S., Anderson, W. C., Weissman, I. L. (2005) Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates. J. Exp. Med. 202, 1599-1611.
    • (2005) J. Exp. Med , vol.202 , pp. 1599-1611
    • Passegué, E.1    Wagers, A.J.2    Giuriato, S.3    Anderson, W.C.4    Weissman, I.L.5
  • 19
    • 0027185511 scopus 로고
    • Functional heterogeneity is associated with the cell cycle status of murine hematopoietic stem cells
    • Fleming, W. H., Alpern, E. J., Uchida, N., Ikuta, K., Spangrude, G. J., Weissman, I. L. (1993) Functional heterogeneity is associated with the cell cycle status of murine hematopoietic stem cells. J. Cell Biol. 122, 897-902.
    • (1993) J. Cell Biol , vol.122 , pp. 897-902
    • Fleming, W.H.1    Alpern, E.J.2    Uchida, N.3    Ikuta, K.4    Spangrude, G.J.5    Weissman, I.L.6
  • 20
    • 0035871882 scopus 로고    scopus 로고
    • Spatial localization of transplanted hemopoietic stem cells: Inferences for the localization of stem cell niches
    • Nilsson, S. K., Johnston, H. M., Coverdale, J. A. (2001) Spatial localization of transplanted hemopoietic stem cells: inferences for the localization of stem cell niches. Blood 97, 2293-2299.
    • (2001) Blood , vol.97 , pp. 2293-2299
    • Nilsson, S.K.1    Johnston, H.M.2    Coverdale, J.A.3
  • 23
    • 3242669145 scopus 로고    scopus 로고
    • Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche
    • Arai, F., Hirao, A., Ohmura, M., Sato, H., Matsuoka, S., Takubo, K., Ito, K., Koh, G. Y., Suda, T. (2004) Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell 118, 149-161.
    • (2004) Cell , vol.118 , pp. 149-161
    • Arai, F.1    Hirao, A.2    Ohmura, M.3    Sato, H.4    Matsuoka, S.5    Takubo, K.6    Ito, K.7    Koh, G.Y.8    Suda, T.9
  • 29
    • 0032845155 scopus 로고    scopus 로고
    • Prevention of interleukin-8-induced mobilization of hematopoietic progenitor cells in rhesus monkeys by inhibitory antibodies against the metalloproteinase gelatinase B (MMP-9)
    • Pruijt, J. F., Fibbe, W. E., Laterveer, L., Pieters, R. A., Lindley, I. J., Paemen, L., Masure, S., Willemze, R., Opdenakker, G. (1999) Prevention of interleukin-8-induced mobilization of hematopoietic progenitor cells in rhesus monkeys by inhibitory antibodies against the metalloproteinase gelatinase B (MMP-9). Proc. Natl. Acad. Sci. USA 96, 10863-10868.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 10863-10868
    • Pruijt, J.F.1    Fibbe, W.E.2    Laterveer, L.3    Pieters, R.A.4    Lindley, I.J.5    Paemen, L.6    Masure, S.7    Willemze, R.8    Opdenakker, G.9
  • 31
    • 10044223409 scopus 로고    scopus 로고
    • Hematopoietic stem cell repopulating ability can be maintained in vitro by some primary endothelial cells
    • Li, W., Johnson, S. A., Shelley, W. C., Yoder, M. C. (2004) Hematopoietic stem cell repopulating ability can be maintained in vitro by some primary endothelial cells. Exp. Hematol. 32, 1226-1237.
    • (2004) Exp. Hematol , vol.32 , pp. 1226-1237
    • Li, W.1    Johnson, S.A.2    Shelley, W.C.3    Yoder, M.C.4
  • 33
    • 33845445939 scopus 로고    scopus 로고
    • Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches
    • Sugiyama, T., Kohara, H., Noda, M., Nagasawa, T. (2006) Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches. Immunity 25, 977-988.
    • (2006) Immunity , vol.25 , pp. 977-988
    • Sugiyama, T.1    Kohara, H.2    Noda, M.3    Nagasawa, T.4
  • 34
    • 39749164920 scopus 로고    scopus 로고
    • Haematopoietic stem cell release is regulated by circadian oscillations
    • Méndez-Ferrer, S., Lucas, D., Battista, M., Frenette, P. S. (2008) Haematopoietic stem cell release is regulated by circadian oscillations. Nature 452, 442-447.
    • (2008) Nature , vol.452 , pp. 442-447
    • Méndez-Ferrer, S.1    Lucas, D.2    Battista, M.3    Frenette, P.S.4
  • 35
    • 31044450303 scopus 로고    scopus 로고
    • Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow
    • Katayama, Y., Battista, M., Kao, W. M., Hidalgo, A., Peired, A. J., Thomas, S. A., Frenette, P. S. (2006) Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow. Cell 124, 407-421.
    • (2006) Cell , vol.124 , pp. 407-421
    • Katayama, Y.1    Battista, M.2    Kao, W.M.3    Hidalgo, A.4    Peired, A.J.5    Thomas, S.A.6    Frenette, P.S.7
  • 38
    • 35548936968 scopus 로고    scopus 로고
    • A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the lowoxygenic niche
    • Jang, Y. Y., Sharkis, S. J. (2007) A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the lowoxygenic niche. Blood 110, 3056-3063.
    • (2007) Blood , vol.110 , pp. 3056-3063
    • Jang, Y.Y.1    Sharkis, S.J.2
  • 39
    • 34248359065 scopus 로고    scopus 로고
    • Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia
    • Parmar, K., Mauch, P., Vergilio, J. A., Sackstein, R., Down, J. D. (2007) Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia. Proc. Natl. Acad. Sci. USA 104, 5431-5436.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 5431-5436
    • Parmar, K.1    Mauch, P.2    Vergilio, J.A.3    Sackstein, R.4    Down, J.D.5
  • 41
    • 61849173436 scopus 로고    scopus 로고
    • CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure
    • Fiegl, M., Samudio, I., Clise-Dwyer, K., Burks, J. K., Mnjoyan, Z., Andreeff, M. (2009) CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure. Blood 113, 1504-1512.
    • (2009) Blood , vol.113 , pp. 1504-1512
    • Fiegl, M.1    Samudio, I.2    Clise-Dwyer, K.3    Burks, J.K.4    Mnjoyan, Z.5    Andreeff, M.6
  • 43
    • 33646419510 scopus 로고    scopus 로고
    • Mobilization as a preparative regimen for hematopoietic stem cell transplantation
    • Chen, J., Larochelle, A., Fricker, S., Bridger, G., Dunbar, C. E., Abkowitz, J. L. (2006) Mobilization as a preparative regimen for hematopoietic stem cell transplantation. Blood 107, 3764-3771.
    • (2006) Blood , vol.107 , pp. 3764-3771
    • Chen, J.1    Larochelle, A.2    Fricker, S.3    Bridger, G.4    Dunbar, C.E.5    Abkowitz, J.L.6
  • 44
    • 57849108116 scopus 로고    scopus 로고
    • Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells
    • Colmone, A., Amorim, M., Pontier, A. L., Wang, S., Jablonski, E., Sipkins, D. A. (2008) Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells. Science 322, 1861-1865.
    • (2008) Science , vol.322 , pp. 1861-1865
    • Colmone, A.1    Amorim, M.2    Pontier, A.L.3    Wang, S.4    Jablonski, E.5    Sipkins, D.A.6
  • 45
    • 23244435467 scopus 로고    scopus 로고
    • How do stem cells find their way home?
    • Lapidot, T., Dar, A., Kollet, O. (2005) How do stem cells find their way home? Blood 106, 1901-1910.
    • (2005) Blood , vol.106 , pp. 1901-1910
    • Lapidot, T.1    Dar, A.2    Kollet, O.3
  • 46
    • 0032479875 scopus 로고    scopus 로고
    • Hematopoietic progenitor cell rolling in bone marrow microvessels: Parallel contributions by endothelial selectins and vascular cell adhesion molecule 1
    • Mazo, I. B., Gutierrez-Ramos, J. C., Frenette, P. S., Hynes, R. O., Wagner, D. D., von Andrian, U. H. (1998) Hematopoietic progenitor cell rolling in bone marrow microvessels: parallel contributions by endothelial selectins and vascular cell adhesion molecule 1. J. Exp. Med. 188, 465-474.
    • (1998) J. Exp. Med , vol.188 , pp. 465-474
    • Mazo, I.B.1    Gutierrez-Ramos, J.C.2    Frenette, P.S.3    Hynes, R.O.4    Wagner, D.D.5    von Andrian, U.H.6
  • 47
    • 0035889143 scopus 로고    scopus 로고
    • Molecular pathways in bone marrow homing: Dominant role of α(4)β(1) over β(2)-integrins and selectins
    • Papayannopoulou, T., Priestley, G. V., Nakamoto, B., Zafiropoulos, V., Scott, L. M. (2001) Molecular pathways in bone marrow homing: dominant role of α(4)β(1) over β(2)-integrins and selectins. Blood 98, 2403-2411.
    • (2001) Blood , vol.98 , pp. 2403-2411
    • Papayannopoulou, T.1    Priestley, G.V.2    Nakamoto, B.3    Zafiropoulos, V.4    Scott, L.M.5
  • 48
    • 0034210221 scopus 로고    scopus 로고
    • The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: Role in transendothelial/ stromal migration and engraftment of NOD/SCID mice
    • Peled, A., Kollet, O., Ponomaryov, T., Petit, I., Franitza, S., Grabovsky, V., Slav, M. M., Nagler, A., Lider, O., Alon, R., Zipori, D., Lapidot, T. (2000) The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: role in transendothelial/ stromal migration and engraftment of NOD/SCID mice. Blood 95, 3289-3296.
    • (2000) Blood , vol.95 , pp. 3289-3296
    • Peled, A.1    Kollet, O.2    Ponomaryov, T.3    Petit, I.4    Franitza, S.5    Grabovsky, V.6    Slav, M.M.7    Nagler, A.8    Lider, O.9    Alon, R.10    Zipori, D.11    Lapidot, T.12
  • 51
    • 0035874501 scopus 로고    scopus 로고
    • Rapid and efficient homing of human CD34(+)CD38(-/low)CXCR4(+) stem and progenitor cells to the bone marrow and spleen of NOD/SCID and NOD/ SCID/B2m(null) mice
    • Kollet, O., Spiegel, A., Peled, A., Petit, I., Byk, T., Hershkoviz, R., Guetta, E., Barkai, G., Nagler, A., Lapidot, T. (2001) Rapid and efficient homing of human CD34(+)CD38(-/low)CXCR4(+) stem and progenitor cells to the bone marrow and spleen of NOD/SCID and NOD/ SCID/B2m(null) mice. Blood 97, 3283-3291.
    • (2001) Blood , vol.97 , pp. 3283-3291
    • Kollet, O.1    Spiegel, A.2    Peled, A.3    Petit, I.4    Byk, T.5    Hershkoviz, R.6    Guetta, E.7    Barkai, G.8    Nagler, A.9    Lapidot, T.10
  • 54
    • 0034610327 scopus 로고    scopus 로고
    • A distinct glycoform of CD44 is an L-selectin ligand on human hematopoietic cells
    • Dimitroff, C. J., Lee, J. Y., Fuhlbrigge, R. C., Sackstein, R. (2000) A distinct glycoform of CD44 is an L-selectin ligand on human hematopoietic cells. Proc. Natl. Acad. Sci. USA 97, 13841-13846.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 13841-13846
    • Dimitroff, C.J.1    Lee, J.Y.2    Fuhlbrigge, R.C.3    Sackstein, R.4
  • 55
    • 0035844880 scopus 로고    scopus 로고
    • CD44 is a major E-selectin ligand on human hematopoietic progenitor cells
    • Dimitroff, C. J., Lee, J. Y., Rafii, S., Fuhlbrigge, R. C., Sackstein, R. (2001) CD44 is a major E-selectin ligand on human hematopoietic progenitor cells. J. Cell Biol. 153, 1277-1286.
    • (2001) J. Cell Biol , vol.153 , pp. 1277-1286
    • Dimitroff, C.J.1    Lee, J.Y.2    Rafii, S.3    Fuhlbrigge, R.C.4    Sackstein, R.5
  • 56
    • 0028971211 scopus 로고
    • The VLA4/VCAM-1 adhesion pathway defines contrasting mechanisms of lodgement of transplanted murine hemopoietic progenitors between bone marrow and spleen
    • Papayannopoulou, T., Craddock, C., Nakamoto, B., Priestley, G. V., Wolf, N. S. (1995) The VLA4/VCAM-1 adhesion pathway defines contrasting mechanisms of lodgement of transplanted murine hemopoietic progenitors between bone marrow and spleen. Proc. Natl. Acad. Sci. USA 92, 9647-9651.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 9647-9651
    • Papayannopoulou, T.1    Craddock, C.2    Nakamoto, B.3    Priestley, G.V.4    Wolf, N.S.5
  • 57
    • 0032147025 scopus 로고    scopus 로고
    • Role of adhesion molecules in the homing and mobilization of murine hematopoietic stem and progenitor cells
    • Vermeulen, M., Le Pesteur, F., Gagnerault, M. C., Mary, J. Y., Sainteny, F., Lepault, F. (1998) Role of adhesion molecules in the homing and mobilization of murine hematopoietic stem and progenitor cells. Blood 92, 894-900.
    • (1998) Blood , vol.92 , pp. 894-900
    • Vermeulen, M.1    le Pesteur, F.2    Gagnerault, M.C.3    Mary, J.Y.4    Sainteny, F.5    Lepault, F.6
  • 58
    • 0025851410 scopus 로고
    • Fibronectin and VLA-4 in haematopoietic stem cell-microenvironment interactions
    • Williams, D. A., Rios, M., Stephens, C., Patel, V. P. (1991) Fibronectin and VLA-4 in haematopoietic stem cell-microenvironment interactions. Nature 352, 438-441.
    • (1991) Nature , vol.352 , pp. 438-441
    • Williams, D.A.1    Rios, M.2    Stephens, C.3    Patel, V.P.4
  • 59
    • 0035976526 scopus 로고    scopus 로고
    • Physiological migration of hematopoietic stem and progenitor cells
    • Wright, D. E., Wagers, A. J., Gulati, A. P., Johnson, F. L., Weissman, I. L. (2001) Physiological migration of hematopoietic stem and progenitor cells. Science 294, 1933-1936.
    • (2001) Science , vol.294 , pp. 1933-1936
    • Wright, D.E.1    Wagers, A.J.2    Gulati, A.P.3    Johnson, F.L.4    Weissman, I.L.5
  • 60
    • 40749162773 scopus 로고    scopus 로고
    • Chemokine-mobilized adult stem cells; defining a better hematopoietic graft
    • Pelus, L. M., Fukuda, S. (2008) Chemokine-mobilized adult stem cells; defining a better hematopoietic graft. Leukemia 22, 466-473.
    • (2008) Leukemia , vol.22 , pp. 466-473
    • Pelus, L.M.1    Fukuda, S.2
  • 61
    • 36549058333 scopus 로고    scopus 로고
    • Chemokines in hematopoiesis
    • Broxmeyer, H. E. (2008) Chemokines in hematopoiesis. Curr. Opin. Hematol. 15, 49-58.
    • (2008) Curr. Opin. Hematol , vol.15 , pp. 49-58
    • Broxmeyer, H.E.1
  • 62
    • 33749502961 scopus 로고    scopus 로고
    • Cytokines and hematopoietic stem cell mobilization
    • Nervi, B., Link, D. C., DiPersio, J. F. (2006) Cytokines and hematopoietic stem cell mobilization. J. Cell. Biochem. 99, 690-705.
    • (2006) J. Cell. Biochem , vol.99 , pp. 690-705
    • Nervi, B.1    Link, D.C.2    Dipersio, J.F.3
  • 63
    • 0037029654 scopus 로고    scopus 로고
    • Hematopoietic stem cells are uniquely selective in their migratory response to chemokines
    • Wright, D. E., Bowman, E. P., Wagers, A. J., Butcher, E. C., Weissman, I. L. (2002) Hematopoietic stem cells are uniquely selective in their migratory response to chemokines. J. Exp. Med. 195, 1145-1154.
    • (2002) J. Exp. Med , vol.195 , pp. 1145-1154
    • Wright, D.E.1    Bowman, E.P.2    Wagers, A.J.3    Butcher, E.C.4    Weissman, I.L.5
  • 67
    • 0037237648 scopus 로고    scopus 로고
    • Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide
    • Lévesque, J. P., Hendy, J., Takamatsu, Y., Simmons, P. J., Bendall, L. J. (2003) Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide. J. Clin. Invest. 111, 187-196.
    • (2003) J. Clin. Invest , vol.111 , pp. 187-196
    • Lévesque, J.P.1    Hendy, J.2    Takamatsu, Y.3    Simmons, P.J.4    Bendall, L.J.5
  • 68
    • 0028967518 scopus 로고
    • Interleukin-8 induces rapid mobilization of hematopoietic stem cells with radioprotective capacity and long-term myelolymphoid repopulating ability
    • Laterveer, L., Lindley, I. J., Hamilton, M. S., Willemze, R., Fibbe, W. E. (1995) Interleukin-8 induces rapid mobilization of hematopoietic stem cells with radioprotective capacity and long-term myelolymphoid repopulating ability. Blood 85, 2269-2275.
    • (1995) Blood , vol.85 , pp. 2269-2275
    • Laterveer, L.1    Lindley, I.J.2    Hamilton, M.S.3    Willemze, R.4    Fibbe, W.E.5
  • 69
    • 0030048296 scopus 로고    scopus 로고
    • Rapid mobilization of hematopoietic progenitor cells in rhesus monkeys by a single intravenous injection of interleukin-8
    • Laterveer, L., Lindley, I. J., Heemskerk, D. P., Camps, J. A., Pauwels, E. K., Willemze, R., Fibbe, W. E. (1996) Rapid mobilization of hematopoietic progenitor cells in rhesus monkeys by a single intravenous injection of interleukin-8. Blood 87, 781-788.
    • (1996) Blood , vol.87 , pp. 781-788
    • Laterveer, L.1    Lindley, I.J.2    Heemskerk, D.P.3    Camps, J.A.4    Pauwels, E.K.5    Willemze, R.6    Fibbe, W.E.7
  • 70
    • 0032850403 scopus 로고    scopus 로고
    • Mechanisms underlying hematopoietic stem cell mobilization induced by the CXC chemokine interleukin-8
    • Pruijt, J. F., Willemze, R., Fibbe, W. E. (1999) Mechanisms underlying hematopoietic stem cell mobilization induced by the CXC chemokine interleukin-8. Curr. Opin. Hematol. 6, 152-158.
    • (1999) Curr. Opin. Hematol , vol.6 , pp. 152-158
    • Pruijt, J.F.1    Willemze, R.2    Fibbe, W.E.3
  • 71
    • 0032101007 scopus 로고    scopus 로고
    • Anti-LFA-1 blocking antibodies prevent mobilization of hematopoietic progenitor cells induced by interleukin-8
    • Pruijt, J. F., van Kooyk, Y., Figdor, C. G., Lindley, I. J., Willemze, R., Fibbe, W. E. (1998) Anti-LFA-1 blocking antibodies prevent mobilization of hematopoietic progenitor cells induced by interleukin-8. Blood 91, 4099-4105.
    • (1998) Blood , vol.91 , pp. 4099-4105
    • Pruijt, J.F.1    van Kooyk, Y.2    Figdor, C.G.3    Lindley, I.J.4    Willemze, R.5    Fibbe, W.E.6
  • 72
    • 34547932084 scopus 로고    scopus 로고
    • The chemokine GROβ mobilizes early hematopoietic stem cells characterized by enhanced homing and engraftment
    • Fukuda, S., Bian, H., King, A. G., Pelus, L. M. (2007) The chemokine GROβ mobilizes early hematopoietic stem cells characterized by enhanced homing and engraftment. Blood 110, 860-869.
    • (2007) Blood , vol.110 , pp. 860-869
    • Fukuda, S.1    Bian, H.2    King, A.G.3    Pelus, L.M.4
  • 73
    • 33746055312 scopus 로고    scopus 로고
    • Peripheral blood stem cell mobilization: The CXCR2 ligand GROβ rapidly mobilizes hematopoietic stem cells with enhanced engraftment properties
    • Pelus, L. M., Fukuda, S. (2006) Peripheral blood stem cell mobilization: the CXCR2 ligand GROβ rapidly mobilizes hematopoietic stem cells with enhanced engraftment properties. Exp. Hematol. 34, 1010-1020.
    • (2006) Exp. Hematol , vol.34 , pp. 1010-1020
    • Pelus, L.M.1    Fukuda, S.2
  • 75
    • 20144362394 scopus 로고    scopus 로고
    • Augmented mobilization and collection of CD34+ hematopoietic cells from normal human volunteers stimulated with granulocyte-colony-stimulating factor by single-dose administration of AMD3100, a CXCR4 antagonist
    • Liles, W. C., Rodger, E., Broxmeyer, H. E., Dehner, C., Badel, K., Calandra, G., Christensen, J., Wood, B., Price, T. H., Dale, D. C. (2005) Augmented mobilization and collection of CD34+ hematopoietic cells from normal human volunteers stimulated with granulocyte-colony-stimulating factor by single-dose administration of AMD3100, a CXCR4 antagonist. Transfusion 45, 295-300.
    • (2005) Transfusion , vol.45 , pp. 295-300
    • Liles, W.C.1    Rodger, E.2    Broxmeyer, H.E.3    Dehner, C.4    Badel, K.5    Calandra, G.6    Christensen, J.7    Wood, B.8    Price, T.H.9    Dale, D.C.10
  • 77
    • 1842509856 scopus 로고    scopus 로고
    • Rapid mobilization of CD34+ cells following administration of the CXCR4 antagonist AMD3100 to patients with multiple myeloma and non-Hodgkin's lymphoma
    • Devine, S. M., Flomenberg, N., Vesole, D. H., Liesveld, J., Weisdorf, D., Badel, K., Calandra, G., DiPersio, J. F. (2004) Rapid mobilization of CD34+ cells following administration of the CXCR4 antagonist AMD3100 to patients with multiple myeloma and non-Hodgkin's lymphoma. J. Clin. Oncol. 22, 1095-1102.
    • (2004) J. Clin. Oncol , vol.22 , pp. 1095-1102
    • Devine, S.M.1    Flomenberg, N.2    Vesole, D.H.3    Liesveld, J.4    Weisdorf, D.5    Badel, K.6    Calandra, G.7    Dipersio, J.F.8
  • 78
    • 33947245648 scopus 로고    scopus 로고
    • Human progenitor cells rapidly mobilized by AMD3100 repopulate NOD/SCID mice with increased frequency in comparison to cells from the same donor mobilized by granulocyte colony stimulating factor
    • Hess, D. A., Bonde, J., Craft, T. P., Wirthlin, L., Hohm, S., Lahey, R., Todt, L. M., Dipersio, J. F., Devine, S. M., Nolta, J. A. (2007) Human progenitor cells rapidly mobilized by AMD3100 repopulate NOD/SCID mice with increased frequency in comparison to cells from the same donor mobilized by granulocyte colony stimulating factor. Biol. Blood Marrow Transplant. 13, 398-411.
    • (2007) Biol. Blood Marrow Transplant , vol.13 , pp. 398-411
    • Hess, D.A.1    Bonde, J.2    Craft, T.P.3    Wirthlin, L.4    Hohm, S.5    Lahey, R.6    Todt, L.M.7    Dipersio, J.F.8    Devine, S.M.9    Nolta, J.A.10
  • 79
    • 27944510941 scopus 로고    scopus 로고
    • AMD3100- mobilized murine hematopoietic stem cells and T-lymphocytes have identical capacity to induce multilineage stem cell engraftment, donor T-cell chimerism and GVHD in mice compared with G-CSF mobilized cells
    • Abs. 3495
    • Devine, S. M., Liu, F., Holt, M., Link, D., DiPersio, J. (2003) AMD3100- mobilized murine hematopoietic stem cells and T-lymphocytes have identical capacity to induce multilineage stem cell engraftment, donor T-cell chimerism and GVHD in mice compared with G-CSF mobilized cells. Blood (ASH Annual Meeting Abstracts) 102, Abs. 3495.
    • (2003) Blood (ASH Annual Meeting Abstracts) , vol.102
    • Devine, S.M.1    Liu, F.2    Holt, M.3    Link, D.4    Dipersio, J.5
  • 80
    • 53749085874 scopus 로고    scopus 로고
    • A phase II study of plerixafor (AMD3100) plus GCSF for autologous hematopoietic progenitor cell mobilization in patients with Hodgkin lymphoma
    • Cashen, A., Lopez, S., Gao, F., Calandra, G., MacFarland, R., Badel, K., DiPersio, J. (2008) A phase II study of plerixafor (AMD3100) plus GCSF for autologous hematopoietic progenitor cell mobilization in patients with Hodgkin lymphoma. Biol. Blood Marrow Transplant. 14, 1253-1261.
    • (2008) Biol. Blood Marrow Transplant , vol.14 , pp. 1253-1261
    • Cashen, A.1    Lopez, S.2    Gao, F.3    Calandra, G.4    Macfarland, R.5    Badel, K.6    Dipersio, J.7
  • 82
    • 70349348954 scopus 로고    scopus 로고
    • BIO5192, a small molecule inhibitor of VLA-4, mobilizes hematopoietic stem and progenitor cells
    • Ramirez, P., Rettig, M. P., Uy, G. L., Deych, E., Holt, M. S., Ritchey, J. K., DiPersio, J. F. (2009) BIO5192, a small molecule inhibitor of VLA-4, mobilizes hematopoietic stem and progenitor cells. Blood 114, 1340-1343.
    • (2009) Blood , vol.114 , pp. 1340-1343
    • Ramirez, P.1    Rettig, M.P.2    Uy, G.L.3    Deych, E.4    Holt, M.S.5    Ritchey, J.K.6    Dipersio, J.F.7
  • 83
    • 65649141536 scopus 로고    scopus 로고
    • Concurrent blockade of α4-integrin and CXCR4 in hematopoietic stem/progenitor cell mobilization
    • Bonig, H., Watts, K. L., Chang, K. H., Kiem, H. P., Papayannopoulou, T. (2009) Concurrent blockade of α4-integrin and CXCR4 in hematopoietic stem/progenitor cell mobilization. Stem Cells 27, 836-837.
    • (2009) Stem Cells , vol.27 , pp. 836-837
    • Bonig, H.1    Watts, K.L.2    Chang, K.H.3    Kiem, H.P.4    Papayannopoulou, T.5
  • 84
    • 0032055189 scopus 로고    scopus 로고
    • Anti-VLA4/ VCAM-1-induced mobilization requires cooperative signaling through the kit/mkit ligand pathway
    • Papayannopoulou, T., Priestley, G. V., Nakamoto, B. (1998) Anti-VLA4/ VCAM-1-induced mobilization requires cooperative signaling through the kit/mkit ligand pathway. Blood 91, 2231-2239.
    • (1998) Blood , vol.91 , pp. 2231-2239
    • Papayannopoulou, T.1    Priestley, G.V.2    Nakamoto, B.3
  • 85
    • 70349841852 scopus 로고    scopus 로고
    • Removal of the spleen in mice alters the cytokine expression profile of the marrow micro-environment and increases bone formation
    • Martelli, F., Verrucci, M., Migliaccio, G., Zingariello, M., Rana, R. A., Vannucchi, A. M., Migliaccio, A. R. (2009) Removal of the spleen in mice alters the cytokine expression profile of the marrow micro-environment and increases bone formation. Ann. N. Y. Acad. Sci. 1176, 77-86.
    • (2009) Ann. N. Y. Acad. Sci , vol.1176 , pp. 77-86
    • Martelli, F.1    Verrucci, M.2    Migliaccio, G.3    Zingariello, M.4    Rana, R.A.5    Vannucchi, A.M.6    Migliaccio, A.R.7
  • 86
    • 12144288689 scopus 로고    scopus 로고
    • Mobilization studies in mice deficient in either C3 or C3a receptor (C3aR) reveal a novel role for complement in retention of hematopoietic stem/progenitor cells in bone marrow
    • Ratajczak, J., Reca, R., Kucia, M., Majka, M., Allendorf, D. J., Baran, J. T., Janowska-Wieczorek, A., Wetsel, R. A., Ross, G. D., Ratajczak, M. Z. (2004) Mobilization studies in mice deficient in either C3 or C3a receptor (C3aR) reveal a novel role for complement in retention of hematopoietic stem/progenitor cells in bone marrow. Blood 103, 2071-2078.
    • (2004) Blood , vol.103 , pp. 2071-2078
    • Ratajczak, J.1    Reca, R.2    Kucia, M.3    Majka, M.4    Allendorf, D.J.5    Baran, J.T.6    Janowska-Wieczorek, A.7    Wetsel, R.A.8    Ross, G.D.9    Ratajczak, M.Z.10
  • 87
    • 77949424731 scopus 로고    scopus 로고
    • Mobilization studies in complement- deficient mice reveal that optimal AMD3100 mobilization of hematopoietic stem cells depends on complement cascade activation by AMD3100-stimulated granulocytes
    • Lee, H. M., Wysoczynski, M., Liu, R., Shin, D. M., Kucia, M., Botto, M., Ratajczak, J., Ratajczak, M. Z. (2010) Mobilization studies in complement- deficient mice reveal that optimal AMD3100 mobilization of hematopoietic stem cells depends on complement cascade activation by AMD3100-stimulated granulocytes. Leukemia 24, 573-582.
    • (2010) Leukemia , vol.24 , pp. 573-582
    • Lee, H.M.1    Wysoczynski, M.2    Liu, R.3    Shin, D.M.4    Kucia, M.5    Botto, M.6    Ratajczak, J.7    Ratajczak, M.Z.8
  • 88
    • 77950845392 scopus 로고    scopus 로고
    • Fifth complement cascade protein (C5) cleavage fragments disrupt the SDF- 1/CXCR4 axis: Further evidence that innate immunity orchestrates the mobilization of hematopoietic stem/progenitor cells
    • Jalili, A., Shirvaikar, N., Marquez-Curtis, L., Qiu, Y., Korol, C., Lee, H., Turner, A. R., Ratajczak, M. Z., Janowska-Wieczorek, A. (2010) Fifth complement cascade protein (C5) cleavage fragments disrupt the SDF- 1/CXCR4 axis: further evidence that innate immunity orchestrates the mobilization of hematopoietic stem/progenitor cells. Exp. Hematol. 38, 321-332.
    • (2010) Exp. Hematol , vol.38 , pp. 321-332
    • Jalili, A.1    Shirvaikar, N.2    Marquez-Curtis, L.3    Qiu, Y.4    Korol, C.5    Lee, H.6    Turner, A.R.7    Ratajczak, M.Z.8    Janowska-Wieczorek, A.9
  • 89
    • 37349076287 scopus 로고    scopus 로고
    • A novel role of complement in mobilization: Immunodeficient mice are poor granulocyte-colony stimulating factor mobilizers because they lack complement-activating immunoglobulins
    • Reca, R., Cramer, D., Yan, J., Laughlin, M. J., Janowska-Wieczorek, A., Ratajczak, J., Ratajczak, M. Z. (2007) A novel role of complement in mobilization: immunodeficient mice are poor granulocyte-colony stimulating factor mobilizers because they lack complement-activating immunoglobulins. Stem Cells 25, 3093-3100.
    • (2007) Stem Cells , vol.25 , pp. 3093-3100
    • Reca, R.1    Cramer, D.2    Yan, J.3    Laughlin, M.J.4    Janowska-Wieczorek, A.5    Ratajczak, J.6    Ratajczak, M.Z.7
  • 90
    • 70450284427 scopus 로고    scopus 로고
    • Impaired mobilization of hematopoietic stem/progenitor cells in C5-deficient mice supports the pivotal involvement of innate immunity in this process and reveals novel promobilization effects of granulocytes
    • Lee, H. M., Wu, W., Wysoczynski, M., Liu, R., Zuba-Surma, E. K., Kucia, M., Ratajczak, J., Ratajczak, M. Z. (2009) Impaired mobilization of hematopoietic stem/progenitor cells in C5-deficient mice supports the pivotal involvement of innate immunity in this process and reveals novel promobilization effects of granulocytes. Leukemia 23, 2052-2062.
    • (2009) Leukemia , vol.23 , pp. 2052-2062
    • Lee, H.M.1    Wu, W.2    Wysoczynski, M.3    Liu, R.4    Zuba-Surma, E.K.5    Kucia, M.6    Ratajczak, J.7    Ratajczak, M.Z.8
  • 91
    • 79951689118 scopus 로고    scopus 로고
    • Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice
    • Christopher, M. J., Rao, M., Liu, F., Woloszynek, J. R., Link, D. C. (2011) Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice. J. Exp. Med. 208, 251-260.
    • (2011) J. Exp. Med , vol.208 , pp. 251-260
    • Christopher, M.J.1    Rao, M.2    Liu, F.3    Woloszynek, J.R.4    Link, D.C.5
  • 92
    • 0348227697 scopus 로고    scopus 로고
    • Neutrophil-derived MMP-9 mediates synergistic mobilization of hematopoietic stem and progenitor cells by the combination of G-CSF and the chemokines GROβ/CXCL2 and GROβT/CXCL2δ4
    • Pelus, L. M., Bian, H., King, A. G., Fukuda, S. (2004) Neutrophil-derived MMP-9 mediates synergistic mobilization of hematopoietic stem and progenitor cells by the combination of G-CSF and the chemokines GROβ/CXCL2 and GROβT/CXCL2δ4. Blood 103, 110-119.
    • (2004) Blood , vol.103 , pp. 110-119
    • Pelus, L.M.1    Bian, H.2    King, A.G.3    Fukuda, S.4
  • 94
    • 71749121612 scopus 로고    scopus 로고
    • Regulating the leukaemia stem cell
    • Cleary, M. L. (2009) Regulating the leukaemia stem cell. Best Pract. Res. Clin. Haematol. 22, 483-487.
    • (2009) Best Pract. Res. Clin. Haematol , vol.22 , pp. 483-487
    • Cleary, M.L.1
  • 97
    • 0030048565 scopus 로고    scopus 로고
    • Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro
    • Panayiotidis, P., Jones, D., Ganeshaguru, K., Foroni, L., Hoffbrand, A. V. (1996) Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro. Br. J. Haematol. 92, 97-103.
    • (1996) Br. J. Haematol , vol.92 , pp. 97-103
    • Panayiotidis, P.1    Jones, D.2    Ganeshaguru, K.3    Foroni, L.4    Hoffbrand, A.V.5
  • 98
    • 0033105537 scopus 로고    scopus 로고
    • Cell adhesion mediated drug resistance (CAM-DR): Role of integrins and resistance to apoptosis in human myeloma cell lines
    • Damiano, J. S., Cress, A. E., Hazlehurst, L. A., Shtil, A. A., Dalton, W. S. (1999) Cell adhesion mediated drug resistance (CAM-DR): role of integrins and resistance to apoptosis in human myeloma cell lines. Blood 93, 1658-1667.
    • (1999) Blood , vol.93 , pp. 1658-1667
    • Damiano, J.S.1    Cress, A.E.2    Hazlehurst, L.A.3    Shtil, A.A.4    Dalton, W.S.5
  • 99
    • 0036738149 scopus 로고    scopus 로고
    • Stromal cells prevent apoptosis of AML cells by upregulation of anti-apoptotic proteins
    • Konopleva, M., Konoplev, S., Hu, W., Zaritskey, A. Y., Afanasiev, B. V., Andreeff, M. (2002) Stromal cells prevent apoptosis of AML cells by upregulation of anti-apoptotic proteins. Leukemia 16, 1713-1724.
    • (2002) Leukemia , vol.16 , pp. 1713-1724
    • Konopleva, M.1    Konoplev, S.2    Hu, W.3    Zaritskey, A.Y.4    Afanasiev, B.V.5    Andreeff, M.6
  • 101
    • 0038717067 scopus 로고    scopus 로고
    • Bone marrow stromal- derived soluble factors and direct cell contact contribute to de novo drug resistance of myeloma cells by distinct mechanisms
    • Nefedova, Y., Landowski, T. H., Dalton, W. S. (2003) Bone marrow stromal- derived soluble factors and direct cell contact contribute to de novo drug resistance of myeloma cells by distinct mechanisms. Leukemia 17, 1175-1182.
    • (2003) Leukemia , vol.17 , pp. 1175-1182
    • Nefedova, Y.1    Landowski, T.H.2    Dalton, W.S.3
  • 104
    • 33947200199 scopus 로고    scopus 로고
    • Overexpression of CXCR4 predicts adverse overall and event-free survival in patients with unmutated FLT3 acute myeloid leukemia with normal karyotype
    • Konoplev, S., Rassidakis, G. Z., Estey, E., Kantarjian, H., Liakou, C. I., Huang, X., Xiao, L., Andreeff, M., Konopleva, M., Medeiros, L. J. (2007) Overexpression of CXCR4 predicts adverse overall and event-free survival in patients with unmutated FLT3 acute myeloid leukemia with normal karyotype. Cancer 109, 1152-1156.
    • (2007) Cancer , vol.109 , pp. 1152-1156
    • Konoplev, S.1    Rassidakis, G.Z.2    Estey, E.3    Kantarjian, H.4    Liakou, C.I.5    Huang, X.6    Xiao, L.7    Andreeff, M.8    Konopleva, M.9    Medeiros, L.J.10
  • 105
    • 0037606054 scopus 로고    scopus 로고
    • Detection, isolation, and stimulation of quiescent primitive leukemic progenitor cells from patients with acute myeloid leukemia (AML)
    • Guan, Y., Gerhard, B., Hogge, D. E. (2003) Detection, isolation, and stimulation of quiescent primitive leukemic progenitor cells from patients with acute myeloid leukemia (AML). Blood 101, 3142-3149.
    • (2003) Blood , vol.101 , pp. 3142-3149
    • Guan, Y.1    Gerhard, B.2    Hogge, D.E.3
  • 106
    • 2642710893 scopus 로고    scopus 로고
    • The chemokine receptor CXCR-4 is expressed on CD34+ hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1
    • Möhle, R., Bautz, F., Rafii, S., Moore, M. A., Brugger, W., Kanz, L. (1998) The chemokine receptor CXCR-4 is expressed on CD34+ hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1. Blood 91, 4523-4530.
    • (1998) Blood , vol.91 , pp. 4523-4530
    • Möhle, R.1    Bautz, F.2    Rafii, S.3    Moore, M.A.4    Brugger, W.5    Kanz, L.6
  • 108
    • 0033781363 scopus 로고    scopus 로고
    • Functional response of leukaemic blasts to stromal cell-derived factor-1 correlates with preferential expression of the chemokine receptor CXCR4 in acute myelomonocytic and lymphoblastic leukaemia
    • Möhle, R., Schittenhelm, M., Failenschmid, C., Bautz, F., Kratz-Albers, K., Serve, H., Brugger, W., Kanz, L. (2000) Functional response of leukaemic blasts to stromal cell-derived factor-1 correlates with preferential expression of the chemokine receptor CXCR4 in acute myelomonocytic and lymphoblastic leukaemia. Br. J. Haematol. 110, 563-572.
    • (2000) Br. J. Haematol , vol.110 , pp. 563-572
    • Möhle, R.1    Schittenhelm, M.2    Failenschmid, C.3    Bautz, F.4    Kratz-Albers, K.5    Serve, H.6    Brugger, W.7    Kanz, L.8
  • 109
    • 24744448002 scopus 로고    scopus 로고
    • Motility, proliferation, and egress to the circulation of human AML cells are elastase dependent in NOD/SCID chimeric mice
    • Tavor, S., Petit, I., Porozov, S., Goichberg, P., Avigdor, A., Sagiv, S., Nagler, A., Naparstek, E., Lapidot, T. (2005) Motility, proliferation, and egress to the circulation of human AML cells are elastase dependent in NOD/SCID chimeric mice. Blood 106, 2120-2127.
    • (2005) Blood , vol.106 , pp. 2120-2127
    • Tavor, S.1    Petit, I.2    Porozov, S.3    Goichberg, P.4    Avigdor, A.5    Sagiv, S.6    Nagler, A.7    Naparstek, E.8    Lapidot, T.9
  • 110
    • 0035652927 scopus 로고    scopus 로고
    • The chemokine receptor CXCR4 enhances integrin-mediated in vitro adhe-sion and facilitates engraftment of leukemic precursor-B cells in the bone marrow
    • Shen, W., Bendall, L. J., Gottlieb, D. J., Bradstock, K. F. (2001) The chemokine receptor CXCR4 enhances integrin-mediated in vitro adhe-sion and facilitates engraftment of leukemic precursor-B cells in the bone marrow. Exp. Hematol. 29, 1439-1447.
    • (2001) Exp. Hematol , vol.29 , pp. 1439-1447
    • Shen, W.1    Bendall, L.J.2    Gottlieb, D.J.3    Bradstock, K.F.4
  • 111
    • 0033067551 scopus 로고    scopus 로고
    • Ligation of the CD44 adhesion molecule reverses blockage of differentiation in human acute myeloid leukemia
    • Charrad, R. S., Li, Y., Delpech, B., Balitrand, N., Clay, D., Jasmin, C., Chomienne, C., Smadja-Joffe, F. (1999) Ligation of the CD44 adhesion molecule reverses blockage of differentiation in human acute myeloid leukemia. Nat. Med. 5, 669-676.
    • (1999) Nat. Med , vol.5 , pp. 669-676
    • Charrad, R.S.1    Li, Y.2    Delpech, B.3    Balitrand, N.4    Clay, D.5    Jasmin, C.6    Chomienne, C.7    Smadja-Joffe, F.8
  • 113
    • 33749515476 scopus 로고    scopus 로고
    • Targeting of CD44 eradicates human acute myeloid leukemic stem cells
    • Jin, L., Hope, K. J., Zhai, Q., Smadja-Joffe, F., Dick, J. E. (2006) Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat. Med. 12, 1167-1174.
    • (2006) Nat. Med , vol.12 , pp. 1167-1174
    • Jin, L.1    Hope, K.J.2    Zhai, Q.3    Smadja-Joffe, F.4    Dick, J.E.5
  • 114
    • 33749521890 scopus 로고    scopus 로고
    • Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells
    • Krause, D. S., Lazarides, K., von Andrian, U. H., Van Etten, R. A. (2006) Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells. Nat. Med. 12, 1175-1180.
    • (2006) Nat. Med , vol.12 , pp. 1175-1180
    • Krause, D.S.1    Lazarides, K.2    von Andrian, U.H.3    van Etten, R.A.4
  • 118
    • 0031817456 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor (G-CSF) mediated mobilization of leukemic cells in Philadelphia chromosome positive acute lymphoblastic leukemia expressing myeloid antigens (my+Ph+ALL)
    • Kobbe, G., Bauser, U., Rieth, C., Hunerliturkoglu, A., Sohngen, D., Aivado, M., Aul, C., Heyll, A. (1998) Granulocyte colony-stimulating factor (G-CSF) mediated mobilization of leukemic cells in Philadelphia chromosome positive acute lymphoblastic leukemia expressing myeloid antigens (my+Ph+ALL). Am. J. Hematol. 58, 330-333.
    • (1998) Am. J. Hematol , vol.58 , pp. 330-333
    • Kobbe, G.1    Bauser, U.2    Rieth, C.3    Hunerliturkoglu, A.4    Sohngen, D.5    Aivado, M.6    Aul, C.7    Heyll, A.8
  • 120
    • 0034254777 scopus 로고    scopus 로고
    • Ligation of the CD44 adhesion molecule inhibits drug-induced apoptosis in human myeloid leukemia cells
    • Allouche, M., Charrad, R. S., Bettaieb, A., Greenland, C., Grignon, C., Smadja-Joffe, F. (2000) Ligation of the CD44 adhesion molecule inhibits drug-induced apoptosis in human myeloid leukemia cells. Blood 96, 1187-1190.
    • (2000) Blood , vol.96 , pp. 1187-1190
    • Allouche, M.1    Charrad, R.S.2    Bettaieb, A.3    Greenland, C.4    Grignon, C.5    Smadja-Joffe, F.6
  • 121
    • 0036095957 scopus 로고    scopus 로고
    • Effects of anti-CD44 monoclonal antibodies on differentiation and apoptosis of human myeloid leukemia cell lines
    • Charrad, R. S., Gadhoum, Z., Qi, J., Glachant, A., Allouche, M., Jasmin, C., Chomienne, C., Smadja-Joffe, F. (2002) Effects of anti-CD44 monoclonal antibodies on differentiation and apoptosis of human myeloid leukemia cell lines. Blood 99, 290-299.
    • (2002) Blood , vol.99 , pp. 290-299
    • Charrad, R.S.1    Gadhoum, Z.2    Qi, J.3    Glachant, A.4    Allouche, M.5    Jasmin, C.6    Chomienne, C.7    Smadja-Joffe, F.8
  • 123
    • 0032564359 scopus 로고    scopus 로고
    • Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrow
    • Frenette, P. S., Subbarao, S., Mazo, I. B., von Andrian, U. H., Wagner, D. D. (1998) Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrow. Proc. Natl. Acad. Sci. USA 95, 14423-14428.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 14423-14428
    • Frenette, P.S.1    Subbarao, S.2    Mazo, I.B.3    von Andrian, U.H.4    Wagner, D.D.5
  • 124
    • 0027183129 scopus 로고
    • Human acute myeloid leukaemia cells express adhesion proteins and bind to bone marrow fibroblast monolayers and extracellular matrix proteins
    • Kortlepel, K., Bendall, L. J., Gottlieb, D. J. (1993) Human acute myeloid leukaemia cells express adhesion proteins and bind to bone marrow fibroblast monolayers and extracellular matrix proteins. Leukemia 7, 1174-1179.
    • (1993) Leukemia , vol.7 , pp. 1174-1179
    • Kortlepel, K.1    Bendall, L.J.2    Gottlieb, D.J.3
  • 126
    • 3042753829 scopus 로고    scopus 로고
    • Characterization of hematopoietic progenitor mobilization in protease-deficient mice
    • Levesque, J. P., Liu, F., Simmons, P. J., Betsuyaku, T., Senior, R. M., Pham, C., Link, D. C. (2004) Characterization of hematopoietic progenitor mobilization in protease-deficient mice. Blood 104, 65-72.
    • (2004) Blood , vol.104 , pp. 65-72
    • Levesque, J.P.1    Liu, F.2    Simmons, P.J.3    Betsuyaku, T.4    Senior, R.M.5    Pham, C.6    Link, D.C.7
  • 127
    • 0027358691 scopus 로고
    • Human acute myeloid leukemia cells bind to bone marrow stroma via a combination of β-1 and β-2 integrin mechanisms
    • Bendall, L. J., Kortlepel, K., Gottlieb, D. J. (1993) Human acute myeloid leukemia cells bind to bone marrow stroma via a combination of β-1 and β-2 integrin mechanisms. Blood 82, 3125-3132.
    • (1993) Blood , vol.82 , pp. 3125-3132
    • Bendall, L.J.1    Kortlepel, K.2    Gottlieb, D.J.3
  • 128
    • 0030842817 scopus 로고    scopus 로고
    • GM-CSF-mobilized peripheral blood CD34+ cells differ from steady-state bone marrow CD34+ cells in adhesion molecule expression
    • Watanabe, T., Dave, B., Heimann, D. G., Lethaby, E., Kessinger, A., Talmadge, J. E. (1997) GM-CSF-mobilized peripheral blood CD34+ cells differ from steady-state bone marrow CD34+ cells in adhesion molecule expression. Bone Marrow Transplant. 19, 1175-1181.
    • (1997) Bone Marrow Transplant , vol.19 , pp. 1175-1181
    • Watanabe, T.1    Dave, B.2    Heimann, D.G.3    Lethaby, E.4    Kessinger, A.5    Talmadge, J.E.6
  • 129
    • 0028947586 scopus 로고
    • Cytokines increase human hemopoietic cell adhesiveness by activation of very late antigen (VLA)-4 and VLA-5 integrins
    • Lévesque, J. P., Leavesley, D. I., Niutta, S., Vadas, M., Simmons, P. J. (1995) Cytokines increase human hemopoietic cell adhesiveness by activation of very late antigen (VLA)-4 and VLA-5 integrins. J. Exp. Med. 181, 1805-1815.
    • (1995) J. Exp. Med , vol.181 , pp. 1805-1815
    • Lévesque, J.P.1    Leavesley, D.I.2    Niutta, S.3    Vadas, M.4    Simmons, P.J.5
  • 137
    • 0034093830 scopus 로고    scopus 로고
    • Effects of the chemokine stromal cell-derived factor-1 on the migration and localization of precursor-B acute lymphoblastic leukemia cells within bone marrow stromal layers
    • Bradstock, K. F., Makrynikola, V., Bianchi, A., Shen, W., Hewson, J., Gottlieb, D. J. (2000) Effects of the chemokine stromal cell-derived factor-1 on the migration and localization of precursor-B acute lymphoblastic leukemia cells within bone marrow stromal layers. Leukemia 14, 882-888.
    • (2000) Leukemia , vol.14 , pp. 882-888
    • Bradstock, K.F.1    Makrynikola, V.2    Bianchi, A.3    Shen, W.4    Hewson, J.5    Gottlieb, D.J.6
  • 138
    • 1842579596 scopus 로고    scopus 로고
    • Unique SDF-1-induced activation of human precursor-B ALL cells as a result of altered CXCR4 expression and signaling
    • Spiegel, A., Kollet, O., Peled, A., Abel, L., Nagler, A., Bielorai, B., Rechavi, G., Vormoor, J., Lapidot, T. (2004) Unique SDF-1-induced activation of human precursor-B ALL cells as a result of altered CXCR4 expression and signaling. Blood 103, 2900-2907.
    • (2004) Blood , vol.103 , pp. 2900-2907
    • Spiegel, A.1    Kollet, O.2    Peled, A.3    Abel, L.4    Nagler, A.5    Bielorai, B.6    Rechavi, G.7    Vormoor, J.8    Lapidot, T.9
  • 139
    • 0038103869 scopus 로고    scopus 로고
    • Effects of inhibitors of the chemokine receptor CXCR4 on acute lymphoblastic leukemia cells in vitro
    • Juarez, J., Bradstock, K. F., Gottlieb, D. J., Bendall, L. J. (2003) Effects of inhibitors of the chemokine receptor CXCR4 on acute lymphoblastic leukemia cells in vitro. Leukemia 17, 1294-1300.
    • (2003) Leukemia , vol.17 , pp. 1294-1300
    • Juarez, J.1    Bradstock, K.F.2    Gottlieb, D.J.3    Bendall, L.J.4
  • 140
    • 23944488816 scopus 로고    scopus 로고
    • Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells
    • Burger, M., Hartmann, T., Krome, M., Rawluk, J., Tamamura, H., Fujii, N., Kipps, T. J., Burger, J. A. (2005) Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells. Blood 106, 1824-1830.
    • (2005) Blood , vol.106 , pp. 1824-1830
    • Burger, M.1    Hartmann, T.2    Krome, M.3    Rawluk, J.4    Tamamura, H.5    Fujii, N.6    Kipps, T.J.7    Burger, J.A.8


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