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Volumn 6, Issue 12, 2011, Pages

Resveratrol inhibits protein translation in hepatic cells

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INITIATION FACTOR 2ALPHA; INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; PROTEIN KINASE B; RESVERATROL; S6 KINASE; S6 KINASE 1; UNCLASSIFIED DRUG; INITIATION FACTOR 2; INITIATION FACTOR 4F; PROTEIN KINASE INHIBITOR; RAPAMYCIN; STILBENE DERIVATIVE; TARGET OF RAPAMYCIN KINASE; TRANSCRIPTION FACTOR;

EID: 84855262938     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0029513     Document Type: Article
Times cited : (21)

References (80)
  • 1
    • 0141719702 scopus 로고    scopus 로고
    • Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
    • Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, et al. (2003) Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 425: 191-196.
    • (2003) Nature , vol.425 , pp. 191-196
    • Howitz, K.T.1    Bitterman, K.J.2    Cohen, H.Y.3    Lamming, D.W.4    Lavu, S.5
  • 2
    • 3943071801 scopus 로고    scopus 로고
    • Sirtuin activators mimic caloric restriction and delay ageing in metazoans
    • Wood JG, Rogina B, Lavu S, Howitz K, Helfand SL, et al. (2004) Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 430: 686-689.
    • (2004) Nature , vol.430 , pp. 686-689
    • Wood, J.G.1    Rogina, B.2    Lavu, S.3    Howitz, K.4    Helfand, S.L.5
  • 3
    • 31944450272 scopus 로고    scopus 로고
    • Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate
    • Valenzano DR, Terzibasi E, Genade T, Cattaneo A, Domenici L, et al. (2006) Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate. Curr Biol 16: 296-300.
    • (2006) Curr Biol , vol.16 , pp. 296-300
    • Valenzano, D.R.1    Terzibasi, E.2    Genade, T.3    Cattaneo, A.4    Domenici, L.5
  • 4
    • 0031561513 scopus 로고    scopus 로고
    • Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
    • Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, et al. (1997) Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 275: 218-220.
    • (1997) Science , vol.275 , pp. 218-220
    • Jang, M.1    Cai, L.2    Udeani, G.O.3    Slowing, K.V.4    Thomas, C.F.5
  • 5
    • 16844375290 scopus 로고    scopus 로고
    • Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons
    • Parker JA, Arango M, Abderrahmane S, Lambert E, Tourette C, et al. (2005) Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons. Nat Genet 37: 349-350.
    • (2005) Nat Genet , vol.37 , pp. 349-350
    • Parker, J.A.1    Arango, M.2    Abderrahmane, S.3    Lambert, E.4    Tourette, C.5
  • 6
    • 33747886389 scopus 로고    scopus 로고
    • Resveratrol-a boon for treating Alzheimer's disease?
    • Anekonda TS, (2006) Resveratrol-a boon for treating Alzheimer's disease? Brain Res Rev 52: 316-326.
    • (2006) Brain Res Rev , vol.52 , pp. 316-326
    • Anekonda, T.S.1
  • 7
    • 33751072349 scopus 로고    scopus 로고
    • Resveratrol improves health and survival of mice on a high-calorie diet
    • Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, et al. (2006) Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444: 337-342.
    • (2006) Nature , vol.444 , pp. 337-342
    • Baur, J.A.1    Pearson, K.J.2    Price, N.L.3    Jamieson, H.A.4    Lerin, C.5
  • 8
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: the in vivo evidence
    • Baur JA, Sinclair DA, (2006) Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 5: 493-506.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 9
    • 35348972430 scopus 로고    scopus 로고
    • Genetic links between diet and lifespan: shared mechanisms from yeast to humans
    • Bishop NA, Guarente L, (2007) Genetic links between diet and lifespan: shared mechanisms from yeast to humans. Nat Rev Genet 8: 835-844.
    • (2007) Nat Rev Genet , vol.8 , pp. 835-844
    • Bishop, N.A.1    Guarente, L.2
  • 10
    • 50649099122 scopus 로고    scopus 로고
    • Aging and survival: the genetics of life span extension by dietary restriction
    • Mair W, Dillin A, (2008) Aging and survival: the genetics of life span extension by dietary restriction. Annu Rev Biochem 77: 727-754.
    • (2008) Annu Rev Biochem , vol.77 , pp. 727-754
    • Mair, W.1    Dillin, A.2
  • 11
    • 33846423520 scopus 로고    scopus 로고
    • Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans
    • Hansen M, Taubert S, Crawford D, Libina N, Lee SJ, et al. (2007) Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Aging Cell 6: 95-110.
    • (2007) Aging Cell , vol.6 , pp. 95-110
    • Hansen, M.1    Taubert, S.2    Crawford, D.3    Libina, N.4    Lee, S.J.5
  • 12
    • 70349438679 scopus 로고    scopus 로고
    • 4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila
    • Zid BM, Rogers AN, Katewa SD, Vargas MA, Kolipinski MC, et al. (2009) 4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila. Cell 139: 149-160.
    • (2009) Cell , vol.139 , pp. 149-160
    • Zid, B.M.1    Rogers, A.N.2    Katewa, S.D.3    Vargas, M.A.4    Kolipinski, M.C.5
  • 13
  • 14
    • 16644365353 scopus 로고    scopus 로고
    • TOR pathway: linking nutrient sensing to life span
    • Kapahi P, Zid B, (2004) TOR pathway: linking nutrient sensing to life span. Sci Aging Knowledge Environ 2004: PE34.
    • (2004) Sci Aging Knowledge Environ , vol.2004
    • Kapahi, P.1    Zid, B.2
  • 16
    • 33846418352 scopus 로고    scopus 로고
    • Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans
    • Pan KZ, Palter JE, Rogers AN, Olsen A, Chen D, et al. (2007) Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans. Aging Cell 6: 111-119.
    • (2007) Aging Cell , vol.6 , pp. 111-119
    • Pan, K.Z.1    Palter, J.E.2    Rogers, A.N.3    Olsen, A.4    Chen, D.5
  • 17
    • 70349669095 scopus 로고    scopus 로고
    • Ribosomal protein S6 kinase 1 signaling regulates mammalian life span
    • Selman C, Tullet JM, Wieser D, Irvine E, Lingard SJ, et al. (2009) Ribosomal protein S6 kinase 1 signaling regulates mammalian life span. Science 326: 140-144.
    • (2009) Science , vol.326 , pp. 140-144
    • Selman, C.1    Tullet, J.M.2    Wieser, D.3    Irvine, E.4    Lingard, S.J.5
  • 18
    • 72649091698 scopus 로고    scopus 로고
    • Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster
    • Bjedov I, Toivonen JM, Kerr F, Slack C, Jacobson J, et al. (2010) Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster. Cell Metab 11: 35-46.
    • (2010) Cell Metab , vol.11 , pp. 35-46
    • Bjedov, I.1    Toivonen, J.M.2    Kerr, F.3    Slack, C.4    Jacobson, J.5
  • 19
    • 67650944993 scopus 로고    scopus 로고
    • Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
    • Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, et al. (2009) Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 460: 392-395.
    • (2009) Nature , vol.460 , pp. 392-395
    • Harrison, D.E.1    Strong, R.2    Sharp, Z.D.3    Nelson, J.F.4    Astle, C.M.5
  • 20
    • 67349217986 scopus 로고    scopus 로고
    • Molecular mechanisms of mTOR-mediated translational control
    • Ma XM, Blenis J, (2009) Molecular mechanisms of mTOR-mediated translational control. Nat Rev Mol Cell Biol 10: 307-318.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 307-318
    • Ma, X.M.1    Blenis, J.2
  • 21
    • 13444259647 scopus 로고    scopus 로고
    • Regulation of cap-dependent translation by eIF4E inhibitory proteins
    • Richter JD, Sonenberg N, (2005) Regulation of cap-dependent translation by eIF4E inhibitory proteins. Nature 433: 477-480.
    • (2005) Nature , vol.433 , pp. 477-480
    • Richter, J.D.1    Sonenberg, N.2
  • 22
    • 70350418625 scopus 로고    scopus 로고
    • mTOR signaling at a glance
    • Laplante M, Sabatini DM, (2009) mTOR signaling at a glance. J Cell Sci 122: 3589-3594.
    • (2009) J Cell Sci , vol.122 , pp. 3589-3594
    • Laplante, M.1    Sabatini, D.M.2
  • 25
    • 74549131244 scopus 로고    scopus 로고
    • Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo
    • Anisimov VN, Egormin PA, Piskunova TS, Popovich IG, Tyndyk ML, et al. (2010) Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo. Cell Cycle 9: 188-197.
    • (2010) Cell Cycle , vol.9 , pp. 188-197
    • Anisimov, V.N.1    Egormin, P.A.2    Piskunova, T.S.3    Popovich, I.G.4    Tyndyk, M.L.5
  • 26
    • 68149096799 scopus 로고    scopus 로고
    • The pharmacology of mTOR inhibition
    • Guertin DA, Sabatini DM, (2009) The pharmacology of mTOR inhibition. Sci Signal 2: pe24.
    • (2009) Sci Signal , vol.2
    • Guertin, D.A.1    Sabatini, D.M.2
  • 27
    • 34347220473 scopus 로고    scopus 로고
    • Defining the role of mTOR in cancer
    • Guertin DA, Sabatini DM, (2007) Defining the role of mTOR in cancer. Cancer Cell 12: 9-22.
    • (2007) Cancer Cell , vol.12 , pp. 9-22
    • Guertin, D.A.1    Sabatini, D.M.2
  • 29
    • 73449138471 scopus 로고    scopus 로고
    • Translation initiation: a critical signalling node in cancer
    • Robert F, Pelletier J, (2009) Translation initiation: a critical signalling node in cancer. Expert Opin Ther Targets 13: 1279-1293.
    • (2009) Expert Opin Ther Targets , vol.13 , pp. 1279-1293
    • Robert, F.1    Pelletier, J.2
  • 30
    • 67149130284 scopus 로고    scopus 로고
    • Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension
    • Wei M, Fabrizio P, Madia F, Hu J, Ge H, et al. (2009) Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension. PLoS Genet 5: e1000467.
    • (2009) PLoS Genet , vol.5
    • Wei, M.1    Fabrizio, P.2    Madia, F.3    Hu, J.4    Ge, H.5
  • 31
    • 76549104638 scopus 로고    scopus 로고
    • Resveratrol and rapamycin: are they anti-aging drugs?
    • Kaeberlein M, (2010) Resveratrol and rapamycin: are they anti-aging drugs? Bioessays 32: 96-99.
    • (2010) Bioessays , vol.32 , pp. 96-99
    • Kaeberlein, M.1
  • 32
    • 0034219435 scopus 로고    scopus 로고
    • Inhibitory effect of resveratrol on the proliferation of human and rat hepatic derived cell lines
    • Delmas D, Jannin B, Cherkaoui Malki M, Latruffe N, (2000) Inhibitory effect of resveratrol on the proliferation of human and rat hepatic derived cell lines. Oncol Rep 7: 847-852.
    • (2000) Oncol Rep , vol.7 , pp. 847-852
    • Delmas, D.1    Jannin, B.2    Cherkaoui Malki, M.3    Latruffe, N.4
  • 34
    • 0034141942 scopus 로고    scopus 로고
    • Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI
    • Raught B, Gingras AC, Gygi SP, Imataka H, Morino S, et al. (2000) Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI. Embo J 19: 434-444.
    • (2000) Embo J , vol.19 , pp. 434-444
    • Raught, B.1    Gingras, A.C.2    Gygi, S.P.3    Imataka, H.4    Morino, S.5
  • 35
    • 85047689953 scopus 로고
    • 5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?
    • Corton JM, Gillespie JG, Hawley SA, Hardie DG, (1995) 5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells? Eur J Biochem 229: 558-565.
    • (1995) Eur J Biochem , vol.229 , pp. 558-565
    • Corton, J.M.1    Gillespie, J.G.2    Hawley, S.A.3    Hardie, D.G.4
  • 36
    • 0028170210 scopus 로고
    • A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
    • Vlahos CJ, Matter WF, Hui KY, Brown RF, (1994) A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem 269: 5241-5248.
    • (1994) J Biol Chem , vol.269 , pp. 5241-5248
    • Vlahos, C.J.1    Matter, W.F.2    Hui, K.Y.3    Brown, R.F.4
  • 37
    • 0037178781 scopus 로고    scopus 로고
    • Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action
    • Hara K, Maruki Y, Long X, Yoshino K, Oshiro N, et al. (2002) Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action. Cell 110: 177-189.
    • (2002) Cell , vol.110 , pp. 177-189
    • Hara, K.1    Maruki, Y.2    Long, X.3    Yoshino, K.4    Oshiro, N.5
  • 38
    • 0037178786 scopus 로고    scopus 로고
    • mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
    • Kim DH, Sarbassov DD, Ali SM, King JE, Latek RR, et al. (2002) mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 110: 163-175.
    • (2002) Cell , vol.110 , pp. 163-175
    • Kim, D.H.1    Sarbassov, D.D.2    Ali, S.M.3    King, J.E.4    Latek, R.R.5
  • 39
    • 32544446451 scopus 로고    scopus 로고
    • Coping with stress: eIF2 kinases and translational control
    • Wek RC, Jiang HY, Anthony TG, (2006) Coping with stress: eIF2 kinases and translational control. Biochem Soc Trans 34: 7-11.
    • (2006) Biochem Soc Trans , vol.34 , pp. 7-11
    • Wek, R.C.1    Jiang, H.Y.2    Anthony, T.G.3
  • 41
    • 0036667553 scopus 로고    scopus 로고
    • Inhibition of cancer growth by resveratrol is related to its low bioavailability
    • Asensi M, Medina I, Ortega A, Carretero J, Bano MC, et al. (2002) Inhibition of cancer growth by resveratrol is related to its low bioavailability. Free Radic Biol Med 33: 387-398.
    • (2002) Free Radic Biol Med , vol.33 , pp. 387-398
    • Asensi, M.1    Medina, I.2    Ortega, A.3    Carretero, J.4    Bano, M.C.5
  • 42
    • 0037248470 scopus 로고    scopus 로고
    • Absorption of three wine-related polyphenols in three different matrices by healthy subjects
    • Goldberg DM, Yan J, Soleas GJ, (2003) Absorption of three wine-related polyphenols in three different matrices by healthy subjects. Clin Biochem 36: 79-87.
    • (2003) Clin Biochem , vol.36 , pp. 79-87
    • Goldberg, D.M.1    Yan, J.2    Soleas, G.J.3
  • 43
    • 12244285648 scopus 로고    scopus 로고
    • Human, rat, and mouse metabolism of resveratrol
    • Yu C, Shin YG, Chow A, Li Y, Kosmeder JW, et al. (2002) Human, rat, and mouse metabolism of resveratrol. Pharm Res 19: 1907-1914.
    • (2002) Pharm Res , vol.19 , pp. 1907-1914
    • Yu, C.1    Shin, Y.G.2    Chow, A.3    Li, Y.4    Kosmeder, J.W.5
  • 44
    • 1642381216 scopus 로고    scopus 로고
    • Human hepatic cell uptake of resveratrol: involvement of both passive diffusion and carrier-mediated process
    • Lancon A, Delmas D, Osman H, Thenot JP, Jannin B, et al. (2004) Human hepatic cell uptake of resveratrol: involvement of both passive diffusion and carrier-mediated process. Biochem Biophys Res Commun 316: 1132-1137.
    • (2004) Biochem Biophys Res Commun , vol.316 , pp. 1132-1137
    • Lancon, A.1    Delmas, D.2    Osman, H.3    Thenot, J.P.4    Jannin, B.5
  • 45
    • 74849124984 scopus 로고    scopus 로고
    • Inhibition of Mammalian S6 Kinase by Resveratrol Suppresses Autophagy
    • Armour SM, Baur JA, Hsieh SN, Land-Bracha A, Thomas SM, et al. (2009) Inhibition of Mammalian S6 Kinase by Resveratrol Suppresses Autophagy. AGING 1: 515-528.
    • (2009) AGING , vol.1 , pp. 515-528
    • Armour, S.M.1    Baur, J.A.2    Hsieh, S.N.3    Land-Bracha, A.4    Thomas, S.M.5
  • 47
    • 77950127881 scopus 로고    scopus 로고
    • SIRT1 negatively regulates the mammalian target of rapamycin
    • Ghosh HS, McBurney M, Robbins PD, (2010) SIRT1 negatively regulates the mammalian target of rapamycin. PLoS One 5: e9199.
    • (2010) PLoS One , vol.5
    • Ghosh, H.S.1    McBurney, M.2    Robbins, P.D.3
  • 48
    • 67650297506 scopus 로고    scopus 로고
    • Cancer prevention and treatment with resveratrol: from rodent studies to clinical trials
    • Bishayee A, (2009) Cancer prevention and treatment with resveratrol: from rodent studies to clinical trials. Cancer Prev Res (Phila) 2: 409-418.
    • (2009) Cancer Prev Res (Phila) , vol.2 , pp. 409-418
    • Bishayee, A.1
  • 49
    • 62549154478 scopus 로고    scopus 로고
    • Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis
    • Bishayee A, Dhir N, (2009) Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis. Chem Biol Interact 179: 131-144.
    • (2009) Chem Biol Interact , vol.179 , pp. 131-144
    • Bishayee, A.1    Dhir, N.2
  • 50
    • 64349104998 scopus 로고    scopus 로고
    • mTOR inhibitors for hepatocellular cancer: a forward-moving target
    • Treiber G, (2009) mTOR inhibitors for hepatocellular cancer: a forward-moving target. Expert Rev Anticancer Ther 9: 247-261.
    • (2009) Expert Rev Anticancer Ther , vol.9 , pp. 247-261
    • Treiber, G.1
  • 52
    • 66149173551 scopus 로고    scopus 로고
    • Aging and cancer cell biology, 2009
    • Campisi J, Yaswen P, (2009) Aging and cancer cell biology, 2009. Aging Cell 8: 221-225.
    • (2009) Aging Cell , vol.8 , pp. 221-225
    • Campisi, J.1    Yaswen, P.2
  • 53
    • 62449178216 scopus 로고    scopus 로고
    • The critical role of the class III histone deacetylase SIRT1 in cancer
    • Liu T, Liu PY, Marshall GM, (2009) The critical role of the class III histone deacetylase SIRT1 in cancer. Cancer Res 69: 1702-1705.
    • (2009) Cancer Res , vol.69 , pp. 1702-1705
    • Liu, T.1    Liu, P.Y.2    Marshall, G.M.3
  • 54
    • 0037416211 scopus 로고    scopus 로고
    • Stress-induced gene expression requires programmed recovery from translational repression
    • Novoa I, Zhang Y, Zeng H, Jungreis R, Harding HP, et al. (2003) Stress-induced gene expression requires programmed recovery from translational repression. EMBO J 22: 1180-1187.
    • (2003) EMBO J , vol.22 , pp. 1180-1187
    • Novoa, I.1    Zhang, Y.2    Zeng, H.3    Jungreis, R.4    Harding, H.P.5
  • 55
    • 0242361561 scopus 로고    scopus 로고
    • Oncogenic Ras and Akt signaling contribute to glioblastoma formation by differential recruitment of existing mRNAs to polysomes
    • Rajasekhar VK, Viale A, Socci ND, Wiedmann M, Hu X, et al. (2003) Oncogenic Ras and Akt signaling contribute to glioblastoma formation by differential recruitment of existing mRNAs to polysomes. Mol Cell 12: 889-901.
    • (2003) Mol Cell , vol.12 , pp. 889-901
    • Rajasekhar, V.K.1    Viale, A.2    Socci, N.D.3    Wiedmann, M.4    Hu, X.5
  • 56
    • 74049092809 scopus 로고    scopus 로고
    • Calories and carcinogenesis: lessons learned from 30 years of calorie restriction research
    • Hursting SD, Smith SM, Lashinger LM, Harvey AE, Perkins SN, (2010) Calories and carcinogenesis: lessons learned from 30 years of calorie restriction research. Carcinogenesis 31: 83-89.
    • (2010) Carcinogenesis , vol.31 , pp. 83-89
    • Hursting, S.D.1    Smith, S.M.2    Lashinger, L.M.3    Harvey, A.E.4    Perkins, S.N.5
  • 57
    • 64749108996 scopus 로고    scopus 로고
    • Tumours with PI3K activation are resistant to dietary restriction
    • Kalaany NY, Sabatini DM, (2009) Tumours with PI3K activation are resistant to dietary restriction. Nature 458: 725-731.
    • (2009) Nature , vol.458 , pp. 725-731
    • Kalaany, N.Y.1    Sabatini, D.M.2
  • 58
    • 33746564095 scopus 로고    scopus 로고
    • Activated FOXO-mediated insulin resistance is blocked by reduction of TOR activity
    • Luong N, Davies CR, Wessells RJ, Graham SM, King MT, et al. (2006) Activated FOXO-mediated insulin resistance is blocked by reduction of TOR activity. Cell Metab 4: 133-142.
    • (2006) Cell Metab , vol.4 , pp. 133-142
    • Luong, N.1    Davies, C.R.2    Wessells, R.J.3    Graham, S.M.4    King, M.T.5
  • 60
    • 76049084586 scopus 로고    scopus 로고
    • Target identification using drug affinity responsive target stability (DARTS)
    • Lomenick B, Hao R, Jonai N, Chin RM, Aghajan M, et al. (2009) Target identification using drug affinity responsive target stability (DARTS). Proc Natl Acad Sci U S A 106: 21984-21989.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 21984-21989
    • Lomenick, B.1    Hao, R.2    Jonai, N.3    Chin, R.M.4    Aghajan, M.5
  • 61
    • 46749136505 scopus 로고    scopus 로고
    • Resveratrol: one molecule, many targets
    • Pirola L, Frojdo S, (2008) Resveratrol: one molecule, many targets. IUBMB Life 60: 323-332.
    • (2008) IUBMB Life , vol.60 , pp. 323-332
    • Pirola, L.1    Frojdo, S.2
  • 62
    • 77950348878 scopus 로고    scopus 로고
    • AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol
    • Um JH, Park SJ, Kang H, Yang S, Foretz M, et al. (2010) AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol. Diabetes 59: 554-563.
    • (2010) Diabetes , vol.59 , pp. 554-563
    • Um, J.H.1    Park, S.J.2    Kang, H.3    Yang, S.4    Foretz, M.5
  • 63
    • 77950575506 scopus 로고    scopus 로고
    • AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism
    • Vingtdeux V, Giliberto L, Zhao H, Chandakkar P, Wu Q, et al. (2010) AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism. J Biol Chem 285: 9100-9113.
    • (2010) J Biol Chem , vol.285 , pp. 9100-9113
    • Vingtdeux, V.1    Giliberto, L.2    Zhao, H.3    Chandakkar, P.4    Wu, Q.5
  • 64
    • 76449110705 scopus 로고    scopus 로고
    • Resveratrol modulates tumor cell proliferation and protein translation via SIRT1-dependent AMPK activation
    • Lin JN, Lin VC, Rau KM, Shieh PC, Kuo DH, et al. (2010) Resveratrol modulates tumor cell proliferation and protein translation via SIRT1-dependent AMPK activation. J Agric Food Chem 58: 1584-1592.
    • (2010) J Agric Food Chem , vol.58 , pp. 1584-1592
    • Lin, J.N.1    Lin, V.C.2    Rau, K.M.3    Shieh, P.C.4    Kuo, D.H.5
  • 65
    • 76249124608 scopus 로고    scopus 로고
    • Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation
    • Puissant A, Robert G, Fenouille N, Luciano F, Cassuto JP, et al. (2010) Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation. Cancer Res 70: 1042-1052.
    • (2010) Cancer Res , vol.70 , pp. 1042-1052
    • Puissant, A.1    Robert, G.2    Fenouille, N.3    Luciano, F.4    Cassuto, J.P.5
  • 66
    • 33746862126 scopus 로고    scopus 로고
    • Resveratrol inhibits insulin responses in a SirT1-independent pathway
    • Zhang J, (2006) Resveratrol inhibits insulin responses in a SirT1-independent pathway. Biochem J 397: 519-527.
    • (2006) Biochem J , vol.397 , pp. 519-527
    • Zhang, J.1
  • 68
    • 34447634894 scopus 로고    scopus 로고
    • Does resveratrol activate yeast Sir2 in vivo?
    • Kaeberlein M, Kennedy BK, (2007) Does resveratrol activate yeast Sir2 in vivo? Aging Cell 6: 415-416.
    • (2007) Aging Cell , vol.6 , pp. 415-416
    • Kaeberlein, M.1    Kennedy, B.K.2
  • 69
    • 70350524083 scopus 로고    scopus 로고
    • Resveratrol is not a direct activator of SIRT1 enzyme activity
    • Beher D, Wu J, Cumine S, Kim KW, Lu SC, et al. (2009) Resveratrol is not a direct activator of SIRT1 enzyme activity. Chem Biol Drug Des 74: 619-624.
    • (2009) Chem Biol Drug Des , vol.74 , pp. 619-624
    • Beher, D.1    Wu, J.2    Cumine, S.3    Kim, K.W.4    Lu, S.C.5
  • 70
    • 77950246109 scopus 로고    scopus 로고
    • SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1
    • Pacholec M, Bleasdale JE, Chrunyk B, Cunningham D, Flynn D, et al. (2010) SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1. J Biol Chem 285: 8340-8351.
    • (2010) J Biol Chem , vol.285 , pp. 8340-8351
    • Pacholec, M.1    Bleasdale, J.E.2    Chrunyk, B.3    Cunningham, D.4    Flynn, D.5
  • 71
    • 33645221885 scopus 로고    scopus 로고
    • Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage
    • Solomon JM, Pasupuleti R, Xu L, McDonagh T, Curtis R, et al. (2006) Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. Mol Cell Biol 26: 28-38.
    • (2006) Mol Cell Biol , vol.26 , pp. 28-38
    • Solomon, J.M.1    Pasupuleti, R.2    Xu, L.3    McDonagh, T.4    Curtis, R.5
  • 72
    • 67650563916 scopus 로고    scopus 로고
    • SirT1 is an inhibitor of proliferation and tumor formation in colon cancer
    • Kabra N, Li Z, Chen L, Li B, Zhang X, et al. (2009) SirT1 is an inhibitor of proliferation and tumor formation in colon cancer. J Biol Chem 284: 18210-18217.
    • (2009) J Biol Chem , vol.284 , pp. 18210-18217
    • Kabra, N.1    Li, Z.2    Chen, L.3    Li, B.4    Zhang, X.5
  • 73
    • 64049109876 scopus 로고    scopus 로고
    • STAT3 inhibition of gluconeogenesis is downregulated by SirT1
    • Nie Y, Erion DM, Yuan Z, Dietrich M, Shulman GI, et al. (2009) STAT3 inhibition of gluconeogenesis is downregulated by SirT1. Nat Cell Biol 11: 492-500.
    • (2009) Nat Cell Biol , vol.11 , pp. 492-500
    • Nie, Y.1    Erion, D.M.2    Yuan, Z.3    Dietrich, M.4    Shulman, G.I.5
  • 74
    • 78449241484 scopus 로고    scopus 로고
    • Resveratrol Inhibits mTOR Signaling by Promoting the Interaction between mTOR and DEPTOR
    • Liu M, Wilk SA, Wang A, Zhou L, Wang RH, et al. (2010) Resveratrol Inhibits mTOR Signaling by Promoting the Interaction between mTOR and DEPTOR. J Biol Chem 285: 36387-36394.
    • (2010) J Biol Chem , vol.285 , pp. 36387-36394
    • Liu, M.1    Wilk, S.A.2    Wang, A.3    Zhou, L.4    Wang, R.H.5
  • 75
    • 12344305214 scopus 로고    scopus 로고
    • eIF2 and the control of cell physiology
    • Proud CG, (2005) eIF2 and the control of cell physiology. Semin Cell Dev Biol 16: 3-12.
    • (2005) Semin Cell Dev Biol , vol.16 , pp. 3-12
    • Proud, C.G.1
  • 77
    • 0022460012 scopus 로고
    • Binding properties and biological potencies of insulin-like growth factors in L6 myoblasts
    • Ballard FJ, Read LC, Francis GL, Bagley CJ, Wallace JC, (1986) Binding properties and biological potencies of insulin-like growth factors in L6 myoblasts. Biochem J 233: 223-230.
    • (1986) Biochem J , vol.233 , pp. 223-230
    • Ballard, F.J.1    Read, L.C.2    Francis, G.L.3    Bagley, C.J.4    Wallace, J.C.5
  • 78
    • 0043166936 scopus 로고    scopus 로고
    • Measurement of protein synthesis and degradation in C2C2) myoblasts using extracts of muscle from hormone treated bovine
    • Montgomery JL, Harper WM Jr, Miller MF, Morrow KJ Jr, Blanton JR Jr, (2002) Measurement of protein synthesis and degradation in C2C2) myoblasts using extracts of muscle from hormone treated bovine. Methods Cell Sci 24: 123-129.
    • (2002) Methods Cell Sci , vol.24 , pp. 123-129
    • Montgomery, J.L.1    Harper Jr., W.M.2    Miller, M.F.3    Morrow Jr., K.J.4    Blanton Jr., J.R.5
  • 79
    • 31544463521 scopus 로고    scopus 로고
    • Rapamycin inhibits liver growth during refeeding in rats via control of ribosomal protein translation but not cap-dependent translation initiation
    • Anand P, Gruppuso PA, (2006) Rapamycin inhibits liver growth during refeeding in rats via control of ribosomal protein translation but not cap-dependent translation initiation. J Nutr 136: 27-33.
    • (2006) J Nutr , vol.136 , pp. 27-33
    • Anand, P.1    Gruppuso, P.A.2


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