-
1
-
-
0031444281
-
Resveratrol, a polyphenols compound found in frapes and wine, is an agonist for the estrogen receptor
-
Gehm, B. D.; McAndrews, J. M.; Chien, P. Y.; Jameson, J. L. Resveratrol, a polyphenols compound found in frapes and wine, is an agonist for the estrogen receptor. Proc. Natl. Acad. Sci. U.S.A. 1997, 25, 14138-14143.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.25
, pp. 14138-14143
-
-
Gehm, B.D.1
McAndrews, J.M.2
Chien, P.Y.3
Jameson, J.L.4
-
2
-
-
0032913414
-
Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells
-
DOI 10.1002/(SICI)1097-4652(199906)179:3<297::AID-JCP7>3.0.CO;2-P
-
Lu, R.; Serrero, G. Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells. J. Cell. Physiol. 1999, 179, 297-304. (Pubitemid 29203154)
-
(1999)
Journal of Cellular Physiology
, vol.179
, Issue.3
, pp. 297-304
-
-
Lu, R.1
Serrero, G.2
-
3
-
-
0031561513
-
Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
-
Jang, M.; Cai, L.; Udeani, G. O.; Slowing, K. V.; Thomas, C. F.; Beecher, C. W.; Fong, H. H.; Farnsworth, N. R.; Kinghorn, A. D.; Mehta, R. G.; Moon, R. C.; Pezzuto, J. M. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 1997, 275, 218-220. (Pubitemid 127696281)
-
(1997)
Science
, vol.275
, Issue.5297
, pp. 218-220
-
-
Jang, M.1
Cai, L.2
Udeani, G.O.3
Slowing, K.V.4
Thomas, C.F.5
Beecher, C.W.W.6
Fong, H.H.S.7
Farnsworth, N.R.8
Kinghorn, A.D.9
Mehta, R.G.10
Moon, R.C.11
Pezzuto, J.M.12
-
4
-
-
6344278438
-
Cardiovascular protective effects of resveratrol
-
Bradamante, S.; Barenghi, L.; Villa, A. Cardiovascular protective effects of resveratrol. Cardiovasc. Drug Rev. 2004, 22,169-188.
-
(2004)
Cardiovasc. Drug Rev.
, vol.22
, pp. 169-188
-
-
Bradamante, S.1
Barenghi, L.2
Villa, A.3
-
5
-
-
33845399894
-
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1
-
DOI 10.1016/j.cell.2006.11.013, PII S0092867406014280
-
Lagouge, M.; Argmann, C.; Gerhart-Hines, Z.; Meziane, H.; Lerin, C.; Daussin, F.; Messadeq, N.; Milne, J.; Lambert, P.; Elliott, P.; Geny, B.; Laakso, M.; Puigserver, P.; Auwerx, J. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-Iα. Cell 2006, 127, 1109-1122. (Pubitemid 44894520)
-
(2006)
Cell
, vol.127
, Issue.6
, pp. 1109-1122
-
-
Lagouge, M.1
Argmann, C.2
Gerhart-Hines, Z.3
Meziane, H.4
Lerin, C.5
Daussin, F.6
Messadeq, N.7
Milne, J.8
Lambert, P.9
Elliott, P.10
Geny, B.11
Laakso, M.12
Puigserver, P.13
Auwerx, J.14
-
6
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
Baur, J. A.; Pearson, K. J.; Price, N. L.; Jamieson, H. A.; Lerin, C.; Kalra, A.; Prabhu, V. V.; Allard, J. S.; Lopez-Lluch, G.; Lewis, K.; Pistell, P. J.; Poosala, S.; Becker, K. G.; Boss, O.; Gwinn, D.; Wang, M.; Ramaswamy, S.; Fishbein, K. W.; Spencer, R. G.; Lakatta, E. G.; Le Couteur, D.; Shaw, R. J.; Navas, P.; Puigserver, P.; Ingram, D. K.; de Cabo, R.; Sinclair, D. A. Resveratrol improves health and survival of mice on a high-calorie diet. Nature 2006, 444, 337-342.
-
(2006)
Nature
, vol.444
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
Jamieson, H.A.4
Lerin, C.5
Kalra, A.6
Prabhu, V.V.7
Allard, J.S.8
Lopez-Lluch, G.9
Lewis, K.10
Pistell, P.J.11
Poosala, S.12
Becker, K.G.13
Boss, O.14
Gwinn, D.15
Wang, M.16
Ramaswamy, S.17
Fishbein, K.W.18
Spencer, R.G.19
Lakatta, E.G.20
Le Couteur, D.21
Shaw, R.J.22
Navas, P.23
Puigserver, P.24
Ingram, D.K.25
De Cabo, R.26
Sinclair, D.A.27
more..
-
7
-
-
0037184675
-
Resveratrol protects against global cerebral ischemic injury in gerbils
-
Wang, Q.; Xu, J.; Rottinghaus, G. E.; Simonyi, A.; Lubahn, D.; Sun, G. Y.; Sun, A. Y. Resveratrol protects against global cerebral ischemic injury in gerbils. Brain Res. 2002, 955, 439-447.
-
(2002)
Brain Res.
, vol.955
, pp. 439-447
-
-
Wang, Q.1
Xu, J.2
Rottinghaus, G.E.3
Simonyi, A.4
Lubahn, D.5
Sun, G.Y.6
Sun, A.Y.7
-
8
-
-
18744416824
-
Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction
-
DOI 10.1126/science.1078986
-
Rogina, B.; Helfand, S. L.; Frankel, S. Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction. Science 2002, 298, 1745. (Pubitemid 35404109)
-
(2002)
Science
, vol.298
, Issue.5599
, pp. 1745
-
-
Rogina, B.1
Helfand, S.L.2
Frankel, S.3
-
9
-
-
0037312020
-
How does calorie restriction work?
-
DOI 10.1101/gad.1052903
-
Koubova, J.; Guarente, L. How does calorie restriction work? Genes 2003, 77, 313-321. (Pubitemid 36182188)
-
(2003)
Genes and Development
, vol.17
, Issue.3
, pp. 313-321
-
-
Koubova, J.1
Guarente, L.2
-
10
-
-
0037353433
-
Caloric restriction promotes genomic stability by induction of base excision repair and reversal of its age-related decline
-
Cabelof, D. C.; Yanamadala, S.; Raffoul, J. J.; Guo, Z.; Soofi, A.; Heydari, A. R. Caloric restriction promotes genomic stability by induction of base excision repair and reversal of its age-related decline. DNA Repair 2003, 2, 295-307.
-
(2003)
DNA Repair
, vol.2
, pp. 295-307
-
-
Cabelof, D.C.1
Yanamadala, S.2
Raffoul, J.J.3
Guo, Z.4
Soofi, A.5
Heydari, A.R.6
-
11
-
-
33746862126
-
Resveratrol inhibits insulin responses in a SirT1-independent pathway
-
DOI 10.1042/BJ20050977
-
Zhang, J. Resveratrol inhibits insulin responses in a SirTl-independent pathway. Biochem. J. 2006, 397, 519-527. (Pubitemid 44187510)
-
(2006)
Biochemical Journal
, vol.397
, Issue.3
, pp. 519-527
-
-
Zhang, J.1
-
12
-
-
3943071801
-
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
-
DOI 10.1038/nature02789
-
Wood, J. G.; Rogina, B.; Lavu, S.; Howitz, K.; Helfand, S. L.; Tatar, M.; Sinclair, D. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 2004, 430, 686-689. (Pubitemid 39061685)
-
(2004)
Nature
, vol.430
, Issue.7000
, pp. 686-689
-
-
Wood, J.G.1
Regina, B.2
Lavu, S.3
Hewitz, K.4
Helfand, S.L.5
Tatar, M.6
Sinclair, D.7
-
13
-
-
85047689953
-
5aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?
-
Corton, J. M.; Gillespie, J. G.; Hawley, S. A.; Hardie, D. G. 5aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells? Eur. J. Biochem. 1995, 229, 558-565.
-
(1995)
Eur. J. Biochem.
, vol.229
, pp. 558-565
-
-
Corton, J.M.1
Gillespie, J.G.2
Hawley, S.A.3
Hardie, D.G.4
-
14
-
-
0029561919
-
5′-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C a and native bovine protein phosphatase-2AC
-
Davies, S. P.; Helps, N. R.; Cohen, P. T.; Hardie, D. G. 5′-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C a and native bovine protein phosphatase-2AC. FEBS Lett. 1995, 377, 421-425.
-
(1995)
FEBS Lett.
, vol.377
, pp. 421-425
-
-
Davies, S.P.1
Helps, N.R.2
Cohen, P.T.3
Hardie, D.G.4
-
15
-
-
0029910018
-
Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase
-
Hawley, S. A.; Davison, M.; Woods, A.; Davies, S. P.; Beri, R. K.; Carling, D.; Hardie, D. G. Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase. J. Biol. Chem. 1996, 271, 27879-27887.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 27879-27887
-
-
Hawley, S.A.1
Davison, M.2
Woods, A.3
Davies, S.P.4
Beri, R.K.5
Carling, D.6
Hardie, D.G.7
-
16
-
-
0032973130
-
Dealing with energy demand: The AMP-activated protein kinase
-
DOI 10.1016/S0968-0004(98)01340-1, PII S0968000498013401
-
Kemp, B. E.; Mitchelhill, K. L; Stapleton, D.; Michell, B. J.; Chen, Z. P.; Witters, L. A. Dealing with energy demand: the AMP-activated protein kinase. Trends Biochem. Sci. 1999, 24, 22-25. (Pubitemid 29074459)
-
(1999)
Trends in Biochemical Sciences
, vol.24
, Issue.1
, pp. 22-25
-
-
Kemp, B.E.1
Mitchelhill, K.I.2
Stapleton, D.3
Michell, B.J.4
Chen, Z.-P.5
Witters, L.A.6
-
17
-
-
0034721874
-
In rat hepatocytes glucagon increases mammalian target of rapamycin phosphorylation on serine 2448 but antagonizes the phosphorylation of its downstream targets induced by insulin and amino acids
-
Mothe-Satney, I.; Gautier, N.; Hinault, C.; Lawrence, J. C., Jr.; Van Obberghen, E. In rat hepatocytes glucagon increases mammalian target of rapamycin phosphorylation on serine 2448 but antagonizes the phosphorylation of its downstream targets induced by insulin and amino acids. J. Biol. Chem. 2000, 275, 33836-33843.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33836-33843
-
-
Mothe-Satney, I.1
Gautier, N.2
Hinault, C.3
Lawrence Jr., J.C.4
Van Obberghen, E.5
-
18
-
-
0035498939
-
Hierarchical phosphorylation of the translation inhibitor 4E-BP1
-
Gingras, A. C.; Raught, B.; Gygi, S. P.; Niedzwiecka, A.; Miron, M.; Burley, S. K.; Polakiewicz, R. D.; Wyslouch-Cieszynska, A.; Aebersold, R.; Sonenberg, N. Hierarchical phosphorylation of the translation inhibitor 4E-BP1. Genes Dev. 2001, 15, 2852-2864. (Pubitemid 33042055)
-
(2001)
Genes and Development
, vol.15
, Issue.21
, pp. 2852-2864
-
-
Gingras, A.-C.1
Raught, B.2
Gygi, S.P.3
Niedzwiecka, A.4
Miron, M.5
Burley, S.K.6
Polakiewicz, R.D.7
Wyslouch-Cieszynska, A.8
Aebersold, R.9
Sonenberg, N.10
-
19
-
-
15044340650
-
Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4Ebinding proteins
-
Wang, X.; Beugnet, A.; Murakami, M.; Yamanaka, S.; Proud, C. G. Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4Ebinding proteins. Mol. Cell. Biol. 2005, 25, 2558-2572.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 2558-2572
-
-
Wang, X.1
Beugnet, A.2
Murakami, M.3
Yamanaka, S.4
Proud, C.G.5
-
20
-
-
33746637660
-
Current development of mTOR inhibitors as anticancer agents
-
DOI 10.1038/nrd2062, PII NRD2062
-
Faivre, S.; Kroemer, G.; Raymond, E. Current development of mTOR inhibitors as anticancer agents. Nat. Rev. Drug Discov. 2006, 5, 671-688. (Pubitemid 44151605)
-
(2006)
Nature Reviews Drug Discovery
, vol.5
, Issue.8
, pp. 671-688
-
-
Faivre, S.1
Kroemer, G.2
Raymond, E.3
-
21
-
-
34247844379
-
Resveratrol induces apoptosis in chemoresistant cancer cells via modulation of AMPK signaling pathway
-
DOI 10.1196/annals.1397.047, Signal Transduction Pathways, Part C: Cell Signaling in Health and Disease
-
Hwang, J. T.; Kwak, D. W.; Lin, S. K.; Kim, H. M.; Kim, Y. M.; Park, O. J. Resveratrol induces apoptosis in chemoresistant cancer cells via modulation of AMPK signaling pathway. Ann. N. Y. Acad. Sci. 2007, 1095, 441-448. (Pubitemid 47092474)
-
(2007)
Annals of the New York Academy of Sciences
, vol.1095
, pp. 441-448
-
-
Hwang, J.-T.1
Dong, W.K.2
Sun, K.L.3
Hye, M.K.4
Young, M.K.5
Ock, J.P.6
-
22
-
-
33745962138
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
Baur, J. A.; Pearson, K. J.; Price, N. L.; Jamieson, H. A.; Lerin, C.; Kalra, A.; Prabhu, V. V.; Allard, J. S.; Lopez-Lluch, G.; Lewis, K.; Pistell, P. J.; Poosala, S.; Becker, K. G.; Boss, O.; Gwinn, D.; Wang, M.; Ramaswamy, S.; Fishbein, K. W.; Spencer, R. G.; Lakatta, E. G.; Le Couteur, D.; Shaw, R. J.; Navas, P.; Puigserver, P.; Ingram, D. K.; de Cabo, R.; Sinclair, D. A. Resveratrol improves health and survival of mice on a high-calorie diet. Nat. Rev. Drug Discov. 2006, 5, 493-506.
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 493-506
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
Jamieson, H.A.4
Lerin, C.5
Kalra, A.6
Prabhu, V.V.7
Allard, J.S.8
Lopez-Lluch, G.9
Lewis, K.10
Pistell, P.J.11
Poosala, S.12
Becker, K.G.13
Boss, O.14
Gwinn, D.15
Wang, M.16
Ramaswamy, S.17
Fishbein, K.W.18
Spencer, R.G.19
Lakatta, E.G.20
Le Couteur, D.21
Shaw, R.J.22
Navas, P.23
Puigserver, P.24
Ingram, D.K.25
De Cabo, R.26
Sinclair, D.A.27
more..
-
23
-
-
23844558266
-
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine
-
Wallace, D. C. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu. Rev. Genet. 2005, 39, 359-407.
-
(2005)
Annu. Rev. Genet.
, vol.39
, pp. 359-407
-
-
Wallace, D.C.1
-
24
-
-
0043208912
-
Increased hepatic apoptosis during short-term caloric restriction is not associated with an enhancement in caspase levels
-
DOI 10.1016/S0531-5565(03)00091-3
-
Selman, C.; Kendaiah, S.; Gredilla, R.; Leeuwenburgh, C. Increased hepatic apoptosis during short-term caloric restriction is not associated with an enhancement in caspase levels. Exp. Gerontol. 2003, 38, 897-903. (Pubitemid 36952671)
-
(2003)
Experimental Gerontology
, vol.38
, Issue.8
, pp. 897-903
-
-
Selman, C.1
Kendaiah, S.2
Gredilla, R.3
Leeuwenburgh, C.4
-
25
-
-
1042289764
-
Apigenin induces apoptosis through proteasomal degradation of HER2/neu in HER2/neu-overexpressing breast cancer cells via the phosphatidylinositol 3-kinase/ Akt-dependent pathway
-
Way, T. D.; Kao, M. C.; Lin, J. K. Apigenin induces apoptosis through proteasomal degradation of HER2/neu in HER2/neu-overexpressing breast cancer cells via the phosphatidylinositol 3-kinase/ Akt-dependent pathway. J. Biol. Chem. 2004, 279, 4479-4489.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 4479-4489
-
-
Way, T.D.1
Kao, M.C.2
Lin, J.K.3
-
27
-
-
34547413569
-
Sirtuin functions in health and disease
-
Yamamoto, H.; Schoonjans, K.; Auwerx, J. Sirtuin functions in health and disease. Mol. Endocrinol. 2007, 21, 1745-1755.
-
(2007)
Mol. Endocrinol.
, vol.21
, pp. 1745-1755
-
-
Yamamoto, H.1
Schoonjans, K.2
Auwerx, J.3
-
28
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
Howitz, K. T.; Bitterman, K. J.; Cohen, H. Y.; Lamming, D. W.; Lavu, S.; Wood, J. G.; Zipkin, R. E.; Chung, P.; Kisielewski, A.; Zhang, L. L.; Scherer, B.; Sinclair, D. A. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 2003, 425, 191-196.
-
(2003)
Nature
, vol.425
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
Lamming, D.W.4
Lavu, S.5
Wood, J.G.6
Zipkin, R.E.7
Chung, P.8
Kisielewski, A.9
Zhang, L.L.10
Scherer, B.11
Sinclair, D.A.12
-
29
-
-
33846583673
-
SIR2: Apotential target for calorie restriction mimetics
-
Chen, D.; Guarente, L. SIR2: apotential target for calorie restriction mimetics. Trends Mol. Med. 2007, 13, 64-71.
-
(2007)
Trends Mol. Med.
, vol.13
, pp. 64-71
-
-
Chen, D.1
Guarente, L.2
-
30
-
-
23044437445
-
2+/calmodulin-dependent protein kinase kinase-β acts upstream of AMP-activated protein kinase in mammalian cells
-
DOI 10.1016/j.cmet.2005.06.005, PII S1550413105001701
-
Woods, A.; Dickerson, K.; Heath, R.; Hong, S. P.; Momcilovic, M.; Johnstone, S. R.; Carlson, M.; Carling, D. Ca2+/calmodulin-dependent protein kinase kinase-β acts upstream of AMP-activated protein kinase in mammalian cells. Cell Metab. 2005, 2, 21-33. (Pubitemid 43239822)
-
(2005)
Cell Metabolism
, vol.2
, Issue.1
, pp. 21-33
-
-
Woods, A.1
Dickerson, K.2
Heath, R.3
Hong, S.-P.4
Momcilovic, M.5
Johnstone, S.R.6
Carlson, M.7
Carling, D.8
-
31
-
-
1542618348
-
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
-
Shaw, R. J.; Kosmatka, M.; Bardeesy, N.; Hurley, R. L.; Witters, L. A.; DePinho, R. A.; Cantley, L. C. The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 3329-3335.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 3329-3335
-
-
Shaw, R.J.1
Kosmatka, M.2
Bardeesy, N.3
Hurley, R.L.4
Witters, L.A.5
Depinho, R.A.6
Cantley, L.C.7
-
32
-
-
0032486268
-
Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism
-
DOI 10.1074/jbc.273.23.14484
-
Hara, K.; Yonezawa, K.; Weng, Q. P.; Kozlowski, M. T.; Belham, C.; Avruch, J. Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BPl through a common effector mechanism. J. Biol. Chem. 1998, 273, 14484-14494. (Pubitemid 28319170)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.23
, pp. 14484-14494
-
-
Hara, K.1
Yonezawa, K.2
Weng, Q.-P.3
Kozlowski, M.T.4
Belham, C.5
Avruch, J.6
-
33
-
-
2442648845
-
The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis
-
Ruggero, D.; Montanaro, L.; Ma, L.; Xu, W.; Londei, P.; CordonCardo, C.; Pandolfi, P. P. The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis. Nat. Med. 2004, 10, 484-486.
-
(2004)
Nat. Med.
, vol.10
, pp. 484-486
-
-
Ruggero, D.1
Montanaro, L.2
Ma, L.3
Xu, W.4
Londei, P.5
Cordoncardo, C.6
Pandolfi, P.P.7
-
34
-
-
1642586272
-
Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy
-
Wendel, H. G.; De Stanchina, E.; Fridman, J. S.; Malina, A.; Ray, S.; Kogan, S.; Cordon-Cardo, C.; Pelletier, J.; Lowe, S. W. Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy. Nature 2004, 428, 332-337.
-
(2004)
Nature
, vol.428
, pp. 332-337
-
-
Wendel, H.G.1
De Stanchina, E.2
Fridman, J.S.3
Malina, A.4
Ray, S.5
Kogan, S.6
Cordon-Cardo, C.7
Pelletier, J.8
Lowe, S.W.9
-
35
-
-
25844459070
-
Long-term estradiol deprivation in breast cancer cells up-regulates growth factor signaling and enhances estrogen sensitivity
-
DOI 10.1677/erc.1.01018, Growth Factor Signalling snd Therapeutic Resistance in Breast Cancer
-
Santen, R. J.; Song, R. X.; Zhang, Z.; Kumar, R.; Jeng, M. H.; Masamura, A.; Lawrence, J., Jr.; Berstein, L.; Yue, W. Long-term estradiol deprivation in breast cancer cells up-regulates growth factor signaling and enhances estrogen sensitivity. Endocr. Relat. Cancer 2005, 12 (Suppl. 1), S61-S73. (Pubitemid 41395414)
-
(2005)
Endocrine-Related Cancer
, vol.12
, Issue.SUPPL. 1
-
-
Santen, R.J.1
Song, R.X.2
Zhang, Z.3
Kumar, R.4
Jeng, M.-H.5
Masamura, A.6
Lawrence Jr., J.7
Berstein, L.8
Yue, W.9
-
36
-
-
12144255062
-
Combinations of endocrine and biological agents: Present status of therapeutic and presurgical investigations
-
Johnston, S. R. Combinations of endocrine and biological agents: present status of therapeutic and presurgical investigations. Clin. Cancer Res. 2005, 11, 889s-899s.
-
(2005)
Clin. Cancer Res.
, vol.11
-
-
Johnston, S.R.1
-
37
-
-
0035913903
-
SIRT1 functions as an NAD-dependent p53 deacetylase
-
DOI 10.1016/S0092-8674(01)00527-X
-
Vaziri, H.; Dessain, S. K.; Ng Eaton, E.; Imai, S. L; Frye, R. A.; Pandita, T. K.; Guarente, L.; Weinberg, R. A. hSIR2 (SIRTl) functions as an NAD-dependent p53 deacetylase. Cell 2001, 107, 149-159. (Pubitemid 33035942)
-
(2001)
Cell
, vol.107
, Issue.2
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Eaton, E.N.3
Imai, S.-I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
38
-
-
33644875954
-
Neuronal protection by sirtuins in Alzheimer's disease
-
Anekonda, T. S.; Reddy, P. H. Neuronal protection by sirtuins in Alzheimer's disease. J. Neurochem. 2006, 96, 305-313.
-
(2006)
J. Neurochem.
, vol.96
, pp. 305-313
-
-
Anekonda, T.S.1
Reddy, P.H.2
-
39
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
-
DOI 10.1038/nature03354
-
Rodgers, J. T.; Lerin, C.; Haas, W.; Gygi, S. P.; Spiegelman, B. M.; Puigserver, P. Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1. Nature 2005, 434, 113-118. (Pubitemid 40349395)
-
(2005)
Nature
, vol.434
, Issue.7029
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
40
-
-
3042681042
-
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
-
Picard, F.; Kurtev, M.; Chung, N.; Topark-Ngarm, A.; Senawong, T.; Machado De Oliveira, R.; Leid, M.; McBurney, M. W.; Guarente, L. Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ. Nature 2004, 429, 111-116.
-
(2004)
Nature
, vol.429
, pp. 111-116
-
-
Picard, F.1
Kurtev, M.2
Chung, N.3
Topark-Ngarm, A.4
Senawong, T.5
Machado De Oliveira, R.6
Leid, M.7
McBurney, M.W.8
Guarente, L.9
-
41
-
-
33244486764
-
Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic cells
-
Bordone, L.; Motta, M. C.; Picard, F.; Robinson, A.; Jhala, U. S.; Apfeld, J.; McDonagh, T.; Lemieux, M.; McBurney, M.; Szilvasi, A.; Easlon, E. J.; Lin, S. J.; Guarente, L. Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic cells. PLoS Biol. 2006, 4, e31.
-
(2006)
PLoS Biol.
, vol.4
-
-
Bordone, L.1
Motta, M.C.2
Picard, F.3
Robinson, A.4
Jhala, U.S.5
Apfeld, J.6
McDonagh, T.7
Lemieux, M.8
McBurney, M.9
Szilvasi, A.10
Easlon, E.J.11
Lin, S.J.12
Guarente, L.13
-
42
-
-
33750367457
-
Hormonal control of androgen receptor function through SIRTl
-
Fu, M.; Liu, M.; Sauve, A. A.; Jiao, X.; Zhang, X.; Wu, X.; Powell, M. J.; Yang, T.; Gu, W.; Avantaggiati, M. L.; Pattabiraman, N.; Pestell, T. G.; Wang, F.; Quong, A. A.; Wang, C.; Pestell, R. G. Hormonal control of androgen receptor function through SIRTl. Mol. Cell. Biol. 2006, 26, 8122-8135.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 8122-8135
-
-
Fu, M.1
Liu, M.2
Sauve, A.A.3
Jiao, X.4
Zhang, X.5
Wu, X.6
Powell, M.J.7
Yang, T.8
Gu, W.9
Avantaggiati, M.L.10
Pattabiraman, N.11
Pestell, T.G.12
Wang, F.13
Quong, A.A.14
Wang, C.15
Pestell, R.G.16
-
43
-
-
0034802887
-
The p65 (RelA) subunit of NF-KB interacts with the histone deacetylase (HDAC) corepressors HDACl and HDAC2 to negatively regulate gene expression
-
Ashburner, B. P.; Westerheide, S. D.; Baldwin, A. S., Jr. The p65 (RelA) subunit of NF-KB interacts with the histone deacetylase (HDAC) corepressors HDACl and HDAC2 to negatively regulate gene expression. Mol. Cell. Biol. 2001, 21, 7065-7077.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 7065-7077
-
-
Ashburner, B.P.1
Westerheide, S.D.2
Baldwin Jr., A.S.3
-
44
-
-
0037011056
-
Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-KB
-
Chen, L. F.; Mu, Y.; Greene, W. C. Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-KB. EMBO J. 2002, 21, 6539-6548.
-
(2002)
EMBO J.
, vol.21
, pp. 6539-6548
-
-
Chen, L.F.1
Mu, Y.2
Greene, W.C.3
-
45
-
-
0036203419
-
The phosphorylation status of nuclear NF-KB determines its association with CBP/p300 or HDAC-1
-
Zhong, H.; May, M. J.; Jimi, E.; Ghosh, S. The phosphorylation status of nuclear NF-KB determines its association with CBP/p300 or HDAC-1. Mol. Cell 2009, 9, 625-636.
-
(2009)
Mol. Cell
, vol.9
, pp. 625-636
-
-
Zhong, H.1
May, M.J.2
Jimi, E.3
Ghosh, S.4
-
46
-
-
3242719545
-
Modulation of NF-kB-dependent transcription and cell survival by the SIRTl deacetylase
-
Yeung, F.; Hoberg, J. E.; Ramsey, C. S.; Keller, M. D.; Jones, D. R.; Frye, R. A.; Mayo, M. W. Modulation of NF-kB-dependent transcription and cell survival by the SIRTl deacetylase. EMBO J. 2004, 23, 2369-2380.
-
(2004)
EMBO J.
, vol.23
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
Keller, M.D.4
Jones, D.R.5
Frye, R.A.6
Mayo, M.W.7
-
47
-
-
0344420303
-
Connecting LKBl and AMPK links metabolism with cancer
-
Moore, P. Connecting LKBl and AMPK links metabolism with cancer. J. Biol. 2003, 2, 24.
-
(2003)
J. Biol.
, vol.2
, pp. 24
-
-
Moore, P.1
|