The development of label-free cellular assays for drug discovery

Expert Opinion on Drug Discovery

Volumn 6, Issue 12, 2011, Pages 1285-1298

  Fang, Ye ^a  

^a Science and Technology Division Corning Inc ^*  (United States)

Author keywords

Cell based assays; Dynamic mass redistribution; Electric biosensor; Impedance; Label free; Ligand directed functional selectivity; Molecular modes of action; Receptor; Resonant waveguide grating

Indexed keywords

CYCLIC AMP; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE KINASE; TYRPHOSTIN;

BIOSENSOR; CELL ASSAY; CELL HETEROGENEITY; DRUG DEVELOPMENT; DRUG INTERACTION; ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY; HIGH THROUGHPUT SCREENING; HYDRODYNAMICS; ILLUMINATION; IN VITRO STUDY; MOLECULAR MECHANICS; PHENOTYPE; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTEIN PHOSPHORYLATION; REPRODUCIBILITY; REVIEW; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION;

EID: 83455169708     PISSN: 17460441     EISSN: 1746045X     Source Type: Journal    
DOI: 10.1517/17460441.2012.642360     Document Type: Review

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