Dosage-dependent switch from G protein-coupled to G protein-independent signaling by a GPCR

EMBO Journal

Volumn 26, Issue 1, 2007, Pages 53-64

  Sun, Yutong ^a   Huang, Jianyun ^a   Xiang, Yang ^b   Bastepe, Murat ^c   Jüppner, Harald ^c   Kobilka, Brian K ^b   Zhang, J Jillian ^a   Huang, Xin Yun ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b STANFORD UNIVERSITY   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

G proteins; GPCR; MAPK; Src

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; FIBROBLAST; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; CRICETINAE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; GTP-BINDING PROTEINS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 33846245114     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601502     Document Type: Article

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