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Volumn 5, Issue 7, 2010, Pages

Network-based relating pharmacological and genomic spaces for drug target identification

Author keywords

[No Author keywords available]

Indexed keywords

DRUG;

EID: 77955628292     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011764     Document Type: Article
Times cited : (245)

References (40)
  • 2
    • 0347473810 scopus 로고    scopus 로고
    • Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways
    • Parsons AB, Brost RL, Ding H, Li Z, Zhang C, et al. (2003) Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways. Nat Biotechnol 22: 62-69.
    • (2003) Nat Biotechnol , vol.22 , pp. 62-69
    • Parsons, A.B.1    Brost, R.L.2    Ding, H.3    Li, Z.4    Zhang, C.5
  • 4
    • 33749335282 scopus 로고    scopus 로고
    • The Connectivity Map: Using gene-expression signatures to connect small molecules, genes, and disease
    • Lamb J, Crawford ED, Peck D, Modell JW, Blat IC, et al. (2006) The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science 313: 1929-1935.
    • (2006) Science , vol.313 , pp. 1929-1935
    • Lamb, J.1    Crawford, E.D.2    Peck, D.3    Modell, J.W.4    Blat, I.C.5
  • 5
    • 47249146126 scopus 로고    scopus 로고
    • Drug target identification using side-effect similarity
    • Campillos M, Kuhn M, Gavin AC, Jensen LJ, Bork P (2008) Drug target identification using side-effect similarity. Science 321: 263-266.
    • (2008) Science , vol.321 , pp. 263-266
    • Campillos, M.1    Kuhn, M.2    Gavin, A.C.3    Jensen, L.J.4    Bork, P.5
  • 6
    • 33745391215 scopus 로고    scopus 로고
    • Prediction of biological targets for compounds using multiple-category Bayesian models trained on chemogenomics databases
    • Nidhi, Glick M, Davies JW, Jenkins JL (2006) Prediction of biological targets for compounds using multiple-category Bayesian models trained on chemogenomics databases. J Chem Inf Model 46: 1124-1133.
    • (2006) J Chem Inf Model , vol.46 , pp. 1124-1133
    • Nidhi, G.M.1    Davies, J.W.2    Jenkins, J.L.3
  • 7
    • 33646730764 scopus 로고    scopus 로고
    • Robust ligand-based modeling of the biological targets of known drugs
    • Cleves AE, Jain AN (2006) Robust ligand-based modeling of the biological targets of known drugs. J Med Chem 49: 2921-938.
    • (2006) J Med Chem , vol.49 , pp. 2921-2938
    • Cleves, A.E.1    Jain, A.N.2
  • 8
    • 58149116805 scopus 로고    scopus 로고
    • Ligand-target prediction using Winnow and naive Bayesian algorithms and the implications of overall performance statistics
    • Nigsch F, Bender A, Jenkins JL, Mitchell JB (2008) Ligand-target prediction using Winnow and naive Bayesian algorithms and the implications of overall performance statistics. J Chem Inf Model 48: 2313-2325.
    • (2008) J Chem Inf Model , vol.48 , pp. 2313-2325
    • Nigsch, F.1    Bender, A.2    Jenkins, J.L.3    Mitchell, J.B.4
  • 9
    • 33846155913 scopus 로고    scopus 로고
    • Structurebased maximal affinity model predicts small-molecule druggability
    • Cheng AC, Coleman RG, Smyth KT, Cao Q, Soulard P, et al. (2007) Structurebased maximal affinity model predicts small-molecule druggability. Nat Biotechnol 25: 71-75.
    • (2007) Nat Biotechnol , vol.25 , pp. 71-75
    • Cheng, A.C.1    Coleman, R.G.2    Smyth, K.T.3    Cao, Q.4    Soulard, P.5
  • 10
    • 67049100457 scopus 로고    scopus 로고
    • Drug discovery using chemical systems biology: Identification of the protein-ligand binding network to explain the side effects of CETP inhibitors
    • Xie L, Li J, Xie L, Bourne PE (2009) Drug discovery using chemical systems biology: identification of the protein-ligand binding network to explain the side effects of CETP inhibitors. PLoS Comput Biol 5: e1000387.
    • (2009) PLoS Comput Biol , vol.5
    • Xie, L.1    Li, J.2    Xie, L.3    Bourne, P.E.4
  • 11
    • 69849094133 scopus 로고    scopus 로고
    • Supervised prediction of drug-target interactions using bipartite local models
    • Bleakley K, Yamanishi Y (2009) Supervised prediction of drug-target interactions using bipartite local models. Bioinformatics 25: 2397-403
    • (2009) Bioinformatics , vol.25 , pp. 2397-2403
    • Bleakley, K.1    Yamanishi, Y.2
  • 15
    • 34548317031 scopus 로고    scopus 로고
    • Chemogenomic approaches to rational drug design
    • Rognan D (2007) Chemogenomic approaches to rational drug design. Br J Pharmacol 152: 38-52.
    • (2007) Br J Pharmacol , vol.152 , pp. 38-52
    • Rognan, D.1
  • 16
    • 37249026328 scopus 로고    scopus 로고
    • Integrating high-content screening and ligand-target prediction to identify mechanism of action
    • Young DW, Bender A, Hoyt J, McWhinnie E, Chirn GW, et al. (2008) Integrating high-content screening and ligand-target prediction to identify mechanism of action. Nat Chem Biol 4: 59-68.
    • (2008) Nat Chem Biol , vol.4 , pp. 59-68
    • Young, D.W.1    Bender, A.2    Hoyt, J.3    McWhinnie, E.4    Chirn, G.W.5
  • 17
    • 33748669610 scopus 로고    scopus 로고
    • Constructing biological networks through combined literature mining and microarray analysis: A LMMA approach
    • Li S, Wu LJ, Zhang ZQ (2006) Constructing biological networks through combined literature mining and microarray analysis: a LMMA approach. Bioinformatics 22: 2143-2150.
    • (2006) Bioinformatics , vol.22 , pp. 2143-2150
    • Li, S.1    Wu, L.J.2    Zhang, Z.Q.3
  • 19
    • 54249083832 scopus 로고    scopus 로고
    • Drug-therapy networks and the predictions of novel drug targets
    • Spiro Z, Kovacs IA, Csermely P (2008) Drug-therapy networks and the predictions of novel drug targets. J Biol 7: 20.
    • (2008) J Biol , vol.7 , pp. 20
    • Spiro, Z.1    Kovacs, I.A.2    Csermely, P.3
  • 20
    • 0038170311 scopus 로고    scopus 로고
    • Similarity metrics for ligands reflecting the similarity of the target proteins
    • Schuffenhauer A, Floersheim P, Acklin P, Jacoby E (2003) Similarity metrics for ligands reflecting the similarity of the target proteins. J Chem Inf Comput Sci 43: 391-405.
    • (2003) J Chem Inf Comput Sci , vol.43 , pp. 391-405
    • Schuffenhauer, A.1    Floersheim, P.2    Acklin, P.3    Jacoby, E.4
  • 22
    • 77955599721 scopus 로고    scopus 로고
    • The anatomical therapeutic chemical (atc) classification
    • The Anatomical Therapeutic Chemical (ATC) classification [http://www.whocc.no/atcddd/].
  • 23
    • 42349096647 scopus 로고    scopus 로고
    • A global view of drug-therapy interactions
    • Nacher JC, Schwartz JM (2008) A global view of drug-therapy interactions. BMC Pharmacol 8: 5.
    • (2008) BMC Pharmacol , vol.8 , pp. 5
    • Nacher, J.C.1    Schwartz, J.M.2
  • 24
    • 0005180705 scopus 로고    scopus 로고
    • An information-theoretic definition of similarity
    • Shavlik JW,Shavlik JW, eds., San Francisco, CA: Morgan Kaufmann
    • Lin D (1998) An information-theoretic definition of similarity. In: Shavlik JW,Shavlik JW, eds. ICML'98: Proceedings of the Fifteenth International Conference on Machine Learning. San Francisco, CA: Morgan Kaufmann. pp 296-304.
    • (1998) ICML'98: Proceedings of The Fifteenth International Conference on Machine Learning , pp. 296-304
    • Lin, D.1
  • 27
    • 0033861845 scopus 로고    scopus 로고
    • The multiplicity of serotonin receptors: Uselessly diverse molecules or an embarrassment of riches?
    • Roth BL, Kroeze WK, Patel S, Lopez E (2000) The Multiplicity of Serotonin Receptors: Uselessly diverse molecules or an embarrassment of riches? The Neuroscientist 6: 252-262.
    • (2000) The Neuroscientist , vol.6 , pp. 252-262
    • Roth, B.L.1    Kroeze, W.K.2    Patel, S.3    Lopez, E.4
  • 29
    • 0034251736 scopus 로고    scopus 로고
    • The antidepressant nefazodone: A review of its pharmacology, clinical efficacy, adverse effects, dosage, and administration
    • Khouzam HR (2000) The antidepressant nefazodone: A review of its pharmacology, clinical efficacy, adverse effects, dosage, and administration. J Psychosoc Nurs Ment Health Serv 38: 20-25.
    • (2000) J Psychosoc Nurs Ment Health Serv , vol.38 , pp. 20-25
    • Khouzam, H.R.1
  • 31
    • 3843145374 scopus 로고    scopus 로고
    • Estrogens and anti-estrogens: Key mediators of prostate carcinogenesis and new therapeutic candidates
    • Ho SM (2004) Estrogens and anti-estrogens: key mediators of prostate carcinogenesis and new therapeutic candidates. J Cell Biochem 91: 491-503.
    • (2004) J Cell Biochem , vol.91 , pp. 491-503
    • Ho, S.M.1
  • 32
    • 28044447607 scopus 로고    scopus 로고
    • The apoptotic action of estrogen following exhaustive antihormonal therapy: A new clinical treatment strategy
    • Jordan VC, Lewis JS, Osipo C, Cheng D (2005) The apoptotic action of estrogen following exhaustive antihormonal therapy: a new clinical treatment strategy. Breast 14: 624-630.
    • (2005) Breast , vol.14 , pp. 624-630
    • Jordan, V.C.1    Lewis, J.S.2    Osipo, C.3    Cheng, D.4
  • 33
    • 0346656618 scopus 로고    scopus 로고
    • Review of cetirizine hydrochloride for the treatment of allergic disorders
    • Portnoy JM, Dinakar C (2004) Review of cetirizine hydrochloride for the treatment of allergic disorders. Expert Opin Pharmacother 5: 125-135.
    • (2004) Expert Opin Pharmacother , vol.5 , pp. 125-135
    • Portnoy, J.M.1    Dinakar, C.2
  • 34
    • 33644907787 scopus 로고    scopus 로고
    • Repeated-dose effects of mequitazine, cetirizine and dexchlorpheniramine on driving and psychomotor performance
    • Theunissen EL, Vermeeren A, Ramaekers JG (2006) Repeated-dose effects of mequitazine, cetirizine and dexchlorpheniramine on driving and psychomotor performance. Br J Clin Pharmacol 61: 79-86.
    • (2006) Br J Clin Pharmacol , vol.61 , pp. 79-86
    • Theunissen, E.L.1    Vermeeren, A.2    Ramaekers, J.G.3
  • 36
    • 12244275244 scopus 로고    scopus 로고
    • Biological spectra analysis: Linking biological activity profiles to molecular structure
    • Fliri AF, Loging WT, Thadeio PF, Volkmann RA (2005) Biological spectra analysis: Linking biological activity profiles to molecular structure. Proc Natl Acad Sci 102: 261-266.
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 261-266
    • Fliri, A.F.1    Loging, W.T.2    Thadeio, P.F.3    Volkmann, R.A.4
  • 37
    • 54249155522 scopus 로고    scopus 로고
    • Network pharmacology: The next paradigm in drug discovery
    • Hopkins AL (2008) Network pharmacology: the next paradigm in drug discovery. Nat Chem Biol 4: 682-690.
    • (2008) Nat Chem Biol , vol.4 , pp. 682-690
    • Hopkins, A.L.1
  • 38
    • 75549090213 scopus 로고    scopus 로고
    • KEGG for representation and analysis of molecular networks involving diseases and drugs
    • Kanehisa M, Goto S, Furumichi M, Tanabe M, Hirakawa M (2010) KEGG for representation and analysis of molecular networks involving diseases and drugs. Nucleic Acids Res 38: D355-D360.
    • (2010) Nucleic Acids Res , vol.38
    • Kanehisa, M.1    Goto, S.2    Furumichi, M.3    Tanabe, M.4    Hirakawa, M.5
  • 39
    • 0002728955 scopus 로고
    • Implementation of nearest-neighbor searching in an online chemical structure search system
    • Willett P, Winterman V, Bawden D (1986) Implementation of nearest-neighbor searching in an online chemical structure search system. J Chem Inf Comput Sci 26: 36-41.
    • (1986) J Chem Inf Comput Sci , vol.26 , pp. 36-41
    • Willett, P.1    Winterman, V.2    Bawden, D.3
  • 40
    • 43249114206 scopus 로고    scopus 로고
    • Network-based global inference of human disease genes
    • Wu XB, Jiang R, Zhang MQ, Li S (2008) Network-based global inference of human disease genes. Mol Syst Biol 4: 189.
    • (2008) Mol Syst Biol , vol.4 , pp. 189
    • Wu, X.B.1    Jiang, R.2    Zhang, M.Q.3    Li, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.