Screening and identification of small molecule compounds perturbing mitosis using time-dependent cellular response profiles

Analytical Chemistry

Volumn 82, Issue 15, 2010, Pages 6495-6503

  Ke, Ning ^a,b   Xi, Biao ^a,b   Ye, Peifang ^b   Xu, Wanhong ^b   Zheng, Min ^b,c   Mao, Long ^a   Wu, Meng Jou ^a   Zhu, Jenny ^a,b   Wu, Jieying ^b   Zhang, Wenfu ^a   Zhang, Jing ^a   Irelan, Jeff ^a   Wang, Xiaobo ^a   Xu, Xiao ^a,b   Abassi, Yama A ^a  

^a ACEA Biosciences ^*  (United States)

^b Hangzhou High Throughput Drug Screening Center   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; CELL MIGRATION; CELL RESPONSE; CELL-CYCLE PROGRESSION; CELLULAR PATHWAY; CELLULAR PROCESS; CELLULAR RESPONSE; CLUSTERING ANALYSIS; COMPOUND LIBRARIES; FUNCTION OF TIME; MITOTIC ARREST; SCREENING TOOL; SMALL MOLECULES; TIME RESOLUTION; TIME-DEPENDENT; TUBULIN POLYMERIZATION;

CELL DEATH;

MOLECULES;

SMALL INTERFERING RNA;

CHEMISTRY; CLUSTER ANALYSIS; CONFERENCE PAPER; DRUG EFFECT; GENE EXPRESSION REGULATION; HUMAN; METABOLISM; MITOSIS; MOLECULAR LIBRARY; RNA INTERFERENCE; TIME; TUMOR CELL LINE;

CELL LINE, TUMOR; CLUSTER ANALYSIS; GENE EXPRESSION REGULATION; HUMANS; MITOSIS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SMALL MOLECULE LIBRARIES; TIME FACTORS;

EID: 77955131576     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac1007877     Document Type: Conference Paper

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